• Journal of Magnetics
• /
• 제16권4호
• /
• pp.413-416
• /
• 2011

An array of FeCo nanotubes has been successfully fabricated in the pores of porous anodic aluminum oxide (AAO) templates by wetting templates method. The morphology and structure of the nanotube array were characterized by scanning electron microscopy, transmission electron microscopy and x-ray diffraction. The average diameter of the nanotubes was about 200 nm, and the length was more than 10 ${\mu}m$. Vibrating sample magnetometer and superconducting quantum interference device were used to investigate the magnetic properties of the nanotube array. Interaction between the nanotubes has been found to be demagnetizing as expected and the switching field distribution is broad.

• Journal of Photoscience
• /
• 제12권1호
• /
• pp.25-32
• /
• 2005

Binding of N-Alkyl phenothiazines (NAP) to bovine serum albumin (BSA) was studied by spectroscopic methods.It was found that the phenothiazine ring common to all drugs makes major contribution to interaction. However, the nature of alkylamino group at position 10 influences the protein binding significantly. Stern-Volmer plots indicated the presence of static component in the quenching mechanism. The high magnitude of rate constant of quenching indicated that the process of energy transfer occurs by intermolecular interaction and thus the drug-binding site is in close proximity to tryptophan residues of BSA. Binding studies in presence of hydrophobic probe, 8-anilino-1-naphthalein-sulphonic acid showed that there is hydrophobic interaction between drug and the probe and they do not share common sites in BSA. Thermodynamic parameters obtained from data at different temperatures showed that the binding of NAP to BSA predominantly involve hydrophobic forces. The effects of some cations and anions common ions were investigated on NAP-BSA interactions. The CD spectrum of BSA in presence of drug showedthat binding of drug leads to change in the helicity of the protein.

• Journal of information and communication convergence engineering
• /
• 제14권1호
• /
• pp.40-44
• /
• 2016

The device coupling between the stacked top/bottom field-effect transistors (FETs) in two types of monolithic 3D inverter (M3INV) with/without a metal layer in the bottom tier is investigated, and then the regime of the thickness T_ILD and dielectric constant ε_r of the inter-layer distance (ILD), the doping concentration N_d (N_a), and length L_g of the channel, and the side-wall length L_SW where the stacked FETs are coupled are studied. When N_d (N_a) < 10¹⁶ cm^-3 and L_SW < 20 nm, the threshold voltage shift of the top FET varies almost constantly by the gate voltage of the bottom FET, but when N_d (N_a) > 10¹⁶ cm^-3 or L_SW > 20 nm, the shift decreases and increases, respectively. M3INVs with T_ILD ≥ 50 nm and ε_r ≤ 3.9 can neglect the interaction between the stacked FETs, but when T_ILD or ε_r do not meet the above conditions, the interaction must be taken into consideration.

• 한국자기학회지
• /
• 제5권5호
• /
• pp.437-441
• /
• 1995

In order to consider the change of the magnetic anisotropy energy by the Al or Ga substitution for Fe, spin reorientation temperature $T_{SR}$ and Curie temperature $T_{c}$ in $R_{2}Fe_{17-x}M_{x}$ (R=Er, Tm, M=Al, Ga) have been studied both experimentally and theoretically. As a result, $T_{SR}$ and $T_{c}$ for $R_{2}Fe_{17-x}M_{x}$ shift toward higher temperature side with x ($0{\leq}x{\leq}2.0$). The ${\Delta}T_{c}$ the difference of the $T_{c}'s$ between $Er_{2}Fe_{17-x}Al_{x}$ and $Tm_{2}Fe_{17-x}Al_{x}$, is always about 10 K independent of Al-content. But in the case of Ga substitution, the ${\Delta}T_{c}$ increases with Ga-content ; especially, the ${\Delta}T_{c}$ for x=2.0 is 43 K. This value of the ${\Delta}T_{c}$ is not explained by only the difference of the de Gennes fator G between $Er^{3+}$ and $Tm^{3+}$, but it is thought that the values of $J_{ErFe}$ and $J_{TmFe}$ themselves are not equal. ($J_{AB}$ : the exchange interaction between A and B.)

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 2012년도 춘계학술대회 논문집
• /
• pp.897-898
• /
• 2012

• 한국생물정보학회:학술대회논문집
• /
• 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
• /
• pp.77-85
• /
• 2004

A significant portion (about 8% in human genome) of mammalian mRNA sequences contains AU(Adenine and Uracil) rich elements or AREs at their 3' untranslated regions (UTR). These mRNA sequences are usually stable. ARE motifs are assorted into three classes. The importance of AREs in biology is that they make certain mRNA unstable. We analyzed the occurrences of AREs and Alu, and propose a possible mechanism on how human mRNA could acquire and keep A REs at its 3' UTR originated from Alu repeats. Interspersed in the human genome, Alu repeats occupy 5% of the 3' UTR of mRNA sequences. Alu has poly-adenine (poly-A) regions at the end that lead to poly -thymine (poly-T) regions at the end of its complementary Alu. It has been discovered that AREs are present at the poly -T regions. In the all ARE's classes, 27-40% of ARE repeats were found in the poly -T region of Alu with mismatch allowed within 10% of ARE's length from the 3' UTRs of the NCBI's reference m RNA sequence database. We report that Alu, which has been reported as a junk DNA element, is a source of AREs. We found that one third of AREs were derived from the poly -T regions of the complementary Alu.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2008년도 춘계 학술발표회 제20권1호
• /
• pp.257-260
• /
• 2008

최근 초고층 건물 건설의 증가로 인해 많이 사용되고 있는 고강도 콘크리트가 화재 시 폭렬 현상으로 인해 내화성 문제가 대두되고 있다. 이에 본 연구는 화재 피해를 입은 폴리프로필렌 섬유(PP섬유) 혼입 고강도 RC 기둥의 비재하 가열 실험을 거친 시험체의 냉각 후 재하 실험을 통해 부재의 성능을 평가하였다. 화해 후 폭렬이 저감된 기둥의 성능 평가는 단면 손실이 없어 외관상 평가가 힘들기 때문에 잔존 내력을 추정하고 설계 단계에서 화해에 의한 성능 저하를 고려할 수 있는 기반을 만드는 것이 중요하다. 이에 범용 유한요소 해석프로그램인 DIANA(Displacement Analyzer)를 사용하여 부재를 해석하였고, 실제와 거동과 유사한 해석을 위해 온도 곡선은 재하 가열 실험의 온도 분표를 이용하여 단면 모델링에 적용하였다. 화재 노출 시간, 콘크리트 압축강도, 단면 치수를 변수로 적용하여 해석으로 도출된 화재 피해를 입은 고강도 RC 기둥의 P-M 상관곡선을 통해 잔존 성능을 평가하여 설계에 이용하도록 제시하였다.

• Journal of Photoscience
• /
• 제12권3호
• /
• pp.113-117
• /
• 2005

Spectroscopic investigations on the interaction of gabapentin (GBP) with bovine serum albumin (BSA) were reported. The association constant of GBP-BSA system was determined at different temperatures (298, 302, 306 and 311 K) based on the fluorescence quenching results. The GBP was found to quench the fluorescence of BSA through static mechanism. Thermodynamic parameters, the standard enthalpy change, $({\Delta}H^o)$ and the standard entropy change $({\Delta}S^o)$ were observed to be $-9.61{\pm}0.008\;kJ\;mol^{-1}$ and $3.58{\pm}0.011\;Jmol^{-1}K{-1}$ respectively. These indicated that the hydrophobic and electrostatic forces played a role in the interaction of GBP with BSA. The negative value of ${\Delta}G^o$ revealed that the binding reaction is spontaneous. The circular dichroism studies indicated the conformational changes in BSA upon interaction with GBP. The effect of some metal ions on the binding constant was also investigated.

• 생명과학회지
• /
• 제22권9호
• /
• pp.1159-1165
• /
• 2012

${\gamma}$-Aminobutyric acid (GABA)는 신경세포 밖으로 분비된 후 GABA 수송체들(GATs)에 의하여 다시 신경세포 안으로 재흡수 된다. 그러나, GABA 수송체들이 어떻게 연접전막의 위치에 안정적으로 존재하는지 또한 어떤 단백질과 결합하여 조절을 받는지는 알려져 있지 않다. 본 연구에서 효모 two-hybrid system을 이용하여 betaine-${\gamma}$-aminobutyric acid transporter 1 (BGT-1/mGAT2)의 C-말단과 특이적으로 결합하는 Munc-18-interacting (Mint) 단백질을 분리하였다. BGT-1/mGAT2의 C-말단에 존재하는 "T-H-L" 아미노산배열은 Mint2와의 결합에 필수적으로 관여하였다. Mint2은 BGT-1/mGAT2와는 결합하지만, 다른 종류의 GAT와는 결합하지 않았다. 또한 HEK-293T 세포에 Mint2와 BGT-1/mGAT2을 동시에 발현시켜 면역침강한 결과 두 단백질은 같이 면역침강하였으며, 두 단백질은 세포 내에서 세포막 부위에 같이 존재함도 확인하였다. 이러한 결과들은 Mint2가 BGT-1/mGAT2와 결합하여 BGT-1/mGAT2을 조절하는 역할을 함을 시사한다.

• Steel and Composite Structures
• /
• 제8권2호
• /
• pp.145-158
• /
• 2008

In slender sections there is a substantial post-buckling strength provided after the formation of local buckling waves. These waves happened due to normal stresses or shear stresses or both. In this study, a numerical investigation of the behavior of slender I-section beams in combined pure bending and shear has been described. The studied cases were assumed to be prevented from lateral torsional buckling. To achieve this aim, a finite element model that simulates the geometric and material nonlinear nature of the problem has been developed. Moreover, the initial geometric imperfections were included in the model. Different flange and web width-thickness ratios as well as web panel aspect ratios have been considered to draw complete set of interaction diagrams. Results reflect the interaction behavior between flange and web in resisting the combined action of moments and shear. In addition, the web panel aspect ratio will not significantly affect the combined ultimate shear-bending strength as well as the post local buckling strength gained by the section. Results are compared with that predicted by both the Eurocode 3 and the American Iron and Steel specifications, AISI-2001. Finally, an empirical interaction equation has been proposed.