• 기본간호학회지
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• 제8권3호
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• pp.324-333
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• 2001

Purpose: A quasi-experimental study was conducted to identify the effects on Self-efficacy, Fatigue, Coping Skills and Self-care Activities by Korean patients following a Systemic Lupus Erythematosus Self-Management (SLESM) Course. Methods : A two group pre-test and post-test design was used. The participants in the study were forty-one people with Systemic Lupus Erythematosis of which 21 subjects were assigned to the experimental group and 20 to the control group The experimental group received six weekly 2-hour group sessions, while the control group did not receive any intervention Outcome measures included self-efficacy, fatigue, coping skills and self-care activities. Baseline demographic and clinical variables did not differ between the two groups. Results : Patients who Participated in the self-management course showed significant decrease in fatigue (p= .038), improvement in self-efficacy (P= .001) and coping skills (p= ,048), increase in self-care activities (p= .003), and in the number of types of self-care activities(P= .048). Conclusion: Self-efficacy, coping skills and self-care activities improved and fatigue was reduced following the SLESM course. This study showed that a SLESM course is a good nursing intervention that can be offered in community settings.

• BMB Reports
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• 제39권3호
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• pp.229-239
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• 2006

Sj$\"{o}$gren's syndrome (SS) is an autoimmune disorder that affects the salivary glands, leading to xerostomia, and the lacrimal glands, resulting in xerophthalmia. Secondary SS is associated with other autoimmune disorders such as systemic rheumatic diseases and systemic lupus erythematosis (SLE), which can affect multiple organs, including the epidermis. Recent studies have demonstrated that green tea polyphenols (GTPs) possess both anti-inflammatory and anti-apoptotic properties in normal human cells. Epidemiological evidence has indicated that, in comparison to the United States, the incidence of SS, clinical xerostomia and lupus is considerably lower in China and Japan, the two leading green tea-consuming countries. Thus, GTPs might be responsible, in part, for geographical differences in the incidence of xerostomia by reducing the initiation or severity of SS and lupus. Consistent with this, molecular, cellular and animal studies indicate that GTPs could provide protective effects against autoimmune reactions in salivary glands and skin. Therefore, salivary tissues and epidermal keratinocytes could be primary targets for novel therapies using GTPs. This review article evaluates the currently available research data on GTPs, focusing on their potential application in the treatment of the oral manifestations of SS and skin manifestations of SLE.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제29권6호
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• pp.548-553
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• 2007

본 과에서는 우측 악하부의 부종 및 동통을 주소로 내원한 환자를 초기에 우측 악하부 및 협부 농양으로 진단하고 절개 및 배농술을 시행하였으나 증상의 호전이 없고 고열과 림프절 비대가 지속적으로 관찰되었다. 이에 저자 등은 비대된 임프절의 적출술과 다양한 검사를 통하여 괴사성 림프절염을 조직학적으로 확인하고 최종적으로 Kikuchi Fujimoto Disease로 확진하였다. Kikuchi-Fujimoto Disease는 임파선 비대와 고열이 동반되는 원인 불명의 괴사성 임파선염으로 특징지워지는 질환으로서, 적출생검을 통해 증상이 사라지는 경우가 많으므로 상기와 같은 증상이 동반된 환자의 경우 악성 림프종이나 전신성 홍반성 루푸스등의 여러 질환과의 감별진단을 통하여 정확한 치료를 시행하는 것이 추천된다.