• Journal of Audiology & Otology
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• 제24권1호
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• pp.24-28
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• 2020

Background and Objectives: Systemic steroid therapy (SST) and intratympanic steroid injection (ISI) have been the treatment of choice for sudden sensorineural hearing loss (SSNHL). We studied the effect of ISI administered at different intervals on hearing outcomes in patients with SSNHL. Subjects and Methods: We performed a retrospective study of 427 patients diagnosed with SSNHL at Bundang Jesaeng Hospital, of whom 51 patients with SSNHL who received SST and four ISIs were included in this study. Patients were treated with four ISIs either every day for 4 days (group 1) or at intervals (mean duration of interval: 2.21 days) (group 2). Hearing outcomes were evaluated using the pure-tone test before the injection and 14 days, 1 month, and 3 months after the final injection. Recovery rates were classified based on Siegel's criteria. Results: The amount of improvement was 27.67 dB (±20.45) in group 1 and 32.79 dB (±21.42) in group 2. However, there were no significant differences between the two groups (p= 0.714). The recovery rates based on Siegel's criteria were 18/27 (66.7%) and 16/24 (66.7%) in groups 1 and 2, respectively, with no significant difference (p=1.000). Considering only complete recoveries in hearing recovery, the recovery rates were 15/27 (55.6%) and 14/24 (58.3%) in groups 1 and 2, respectively, with no significant difference (p=0.842). Conclusions: There were no significant differences in hearing outcomes or recovery rates after ISI administration every day or at intervals of 2-3 days.

• 한방비만학회지
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• 제9권2호
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• pp.47-56
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• 2009

Objectives The purpose of this study was to investigate the progress of weight and waist circumference(WC) through oriental obesity treatment and clarify the correlation between weight loss and WC change. Methods The subjects were treated from January 2007 to September 2009 in J Oriental Medical Center. Herbal medicine, electroacupuncture, oriental obesity physiotherapy were performed for a month. We checked the change of weight and WC at every treatment. We classified the WC into upper, middle, lower parts specifically and measured them individually. Measurements were analyzed by using one-way repeated measures ANOVA and we also investigated correlation between weight loss and WC change. Results (1) During the first and second treatment sessions, the weight loss was the highest, $0.96{\pm}0.86\;kg$($1.46{\pm}1.32\;%$) and during the 5th and 6th treatment sessions, the lowest $0.37{\pm}0.616\;kg$. The final weight loss was $3.71{\pm}1.476\;kg$($5.51{\pm}2.12\;%$). (2) After 8 treatment sessions, the reductions of upper, middle and lower WC were $3.59{\pm}2.26\;%$, $5.93{\pm}2.75\;%$, $5.51{\pm}3.22\;%$, respectively. As the patients received more treatment, there was a progressive decline in the variation of weight and middle WC. However, the decline rate of upper and middle WC fluctuated during the treatments, forming a W-shaped curve. (3) Analysis of the correlation between the weight loss and WC change shows that the reduction of middle WC was most closely associated with the weight loss. Conclusions This study indicated that the rate of weight loss and WC reduction showed stagnation during the 5th and 6th treatment sessions, and the reduction of middle WC was most closely associated with the weight loss. Since the progress of weight and WC change is an important field of research on obesity, further systemic studies would be needed for the foundation of a clinical guideline.

• Clinical and Experimental Pediatrics
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• 제49권12호
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• pp.1301-1307
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• 2006

목 적 : 신생아기의 청력 소실은 그 빈도가 높으며 조기 발견 및 조기 치료가 예후를 결정하는데 중요하다. 신생아 집중치료실에 입원했던 신생아들은 일반 신생아에 비해 청력 소실의 빈도가 더 높은 것으로 알려지고 있다. 이에 저자들은 신생아 집중치료실에 입원했던 신생아를 대상으로 청력 소실의 발생 빈도와 위험 인자 및 청력 소실의 양상을 조사하기 위해 이 연구를 시행하였다. 방 법 : 2002년 7월부터 2005년 6월까지 3년간 경북대학교병원 신생아 집중치료실에 입원한 환아를 대상으로 ABR 검사를 시행하여 이들의 청력 소실 정도와 이와 관련된 임상 소견을 조사하고 추적 관찰을 시행하였다. 결 과 : 연구 기간 동안 ABR 검사를 받은 환아는 474명으로 총 입원아의 54.0%였고, 검사를 받은 신생아의 13.5%인 64명이 ABR 검사에 이상 소견을 보였다. 이들 64명의 귀 128례의 청력 소실의 양상은 편측 정상이 37례(28.9%)이고 경증, 중등도, 중증 및 초중증 청력 소실이 각각 43례(33.6%), 36례(28.1%), 2례(1.6%) 및 10례(7.8%)로 중증 이상의 청력 소실 빈도는 9.5%였다. 미숙아, 저출생 체중아 및 극소 저출생 체중아, 신생아 가사, 두부 안면 기형 및 amikacin의 15일 이상 사용이 ABR 비정상군에서 유의하게 많았다(P<0.05). 고빌리루빈혈증 환아에서 최고 빌리루빈 수치, 광선치료의 기간과 교환수혈의 시행 여부 모두 ABR 정상군과 비정상군 사이에 유의한 차이를 보이지 않았다. ABR 비정상군 중 15명에서 생후 $8.8{\pm}4.4$개월에 시행한 추적 ABR 검사는 80.0%에서 호전 혹은 정상화되었다. 결 론 : 신생아 집중치료실에 입원했던 신생아는 청력 소실의 위험이 높으므로 이에 대한 체계적이고 효과적인 청력 평가와 관리가 필요하다.

• Journal of Korean Dental Science
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• 제9권2호
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• pp.81-89
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• 2016

Necrotizing periodontal diseases, especially acute necrotizing ulcerative gingivitis (ANUG), it should be noted, occur abruptly and progress rapidly, eventually causing severe soft-tissue and alveolar bone loss. This report presents the cases of two ANUG patients and provides a brief treatment protocol for easy and effective clinical management. After proper diagnosis, sequential treatment with cessation of mechanical brushing, along with a prescription of systemic antibiotics and chlorhexidine as a mouth rinse, scaling, root planing, and supportive periodontal therapy, was utilized. In all cases discussed in this report, there was marked improvement in a few days. ANUG, though an uncommon disease, can be efficiently managed with proper diagnosis and immediate treatment.

• 대한한방부인과학회지
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• 제29권3호
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• pp.91-99
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• 2016

Objectives: The purpose of this study is to report the effect of Korean medical treatment on a patient with atopic eruption of pregnancyMethods: Patient who diagnosed by atopic eruption of pregnancy was enrolled in this study. She received Korean medicine therapies such as herbal medicine, acupuncture and external application. Sopungchungyoung-tangs and Seungmahwangryeon-tangs were prescribed according to the patient’s constitution which was pungyeol. The severity of symptom was evaluated by the severity SCORing for Atopic Dermatitis index (SCORAD index).Results: Subjective symptom such as Systemic pruritus, sleep loss, and Dermatitis lesions was reduced by Korean medicine therapies.Conclusions: The present study suggests that Korean medicine therapies have a effect on atopic eruption of pregnancy.

• 대한족부족관절학회지
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• 제16권2호
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• pp.79-86
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• 2012

Calcaneal fractures account for 2% of all fractures and approximately 60 to 70% of tarsal fractures. These fractures typically are the result of high-energy injury, such as a motor vehicle accident or a fall from a height. The potential for disabling malunion following intrarticular displaced calcaneal fracture is high, regardless of treatment. Fracture displacement typically results in loss of hindfoot height, varus and widening of the hindfoot, with possible subfibular impingement and irritation of the peroneal tendon and/or sural nerve. Frequently, subtalar joint develops posttraumatic arthritis. In symptomatic patients with calcaneal malunion, systemic evaluation is required to determine the source of pain. Nonsurgical treatment, such as activity and shoe modification, bracing, orthoses, and injection, is effective in many patients. Surgical treatment may involve simple ostectomy, subtalar arthrodesis with or without distraction, or corrective calcaneal osteotomy. A high rate of successful arthrodesis and of patient satisfaction has been reported with surgical manamgent.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 춘계학술대회 논문집
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• pp.146-149
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• 2002

It is reported that the mechanical properties of vertebral trabecular bone depend on the density and the mass of bones. Osteoporosis is a systemic skeletal disease caused by low bone mass and microstructure deterioration of trabecular bone. Silva and Gibson (1997) studied the treatment of age-related bone loss using drug therapy. Vertebroplasty is a minimally invasive surgery for the treatment of osteoporosis vertebrae. This procedure includes puncturing vertebrae and filling with Polymethylmethacrylate (PMMA). However, the relative effect of drug therapy and bone cement for osteoporosis treatment is not reported yet. In this study, several 2D models of human vertebral trabecular bone are analyzed by finite element method. The mechanical behaviors of the vertebral trabecular bone treated by the drug therapy and the bone cement are compared. This study shows that bone cement treatment is more effective strategy than drug therapy to prevent the degradation of bone strength.

• 한국임상수의학회지
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• 제35권5호
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• pp.243-246
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• 2018

A 2-day-old Thoroughbred foal weighing 58 kg was admitted to the Equine Hospital of Korea Racing Authority (KRA) Jeju Stud Farm with clinical signs including loss of suckling behavior and barking. Neonatal encephalopathy (NE) was diagnosed based on history and typical clinical signs of NE. The foal seemed to recover in 5 days of intensive care and treatment but then was complicated with the septic arthritis of left hock joint on the $6^{th}$ day of admission. A course of aggressive systemic antimicrobial therapy with joint lavage for 8 days was conducted and the foal was fully recovered and discharged. The follow up on the patient after 2 years revealed that the patient achieved a great success as a racehorse without any unexpected sequel. This report describes a course of NE complicated with septic arthritis in a foal and the clinical outcome of the intensive care and treatment in detail. To our knowledge, this is the first report which describes NE complicated with septic arthritis in a foal in Republic of Korea.

• Journal of Trauma and Injury
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• 제33권2호
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• pp.112-118
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• 2020

In trauma patients, coagulopathy and abnormal increases or decreases in cell counts are frequently observed, and are associated with high mortality and morbidity in the acute phase of trauma. Because major trauma is often life-threatening, and hematologic abnormalities are multi-factorial and transient, major blood loss is usually suspected to be the primary cause of these abnormalities, and much time and cost may be spent attempting to identify a focus of hemorrhage that might or might not actually exist. Persistent abnormalities in the complete blood count, however, require clinical suspicion of other hematologic diseases to minimize improper transfusions and to improve outcomes, including mortality. Physicians at trauma centers should be familiar with the clinical characteristics of hematologic diseases and should consider these diseases in trauma patients. In this report, we present cases of two hematologic disorders found in trauma patients: autoimmune hemolytic anemia induced by systemic lupus erythematosus and myelodysplastic syndrome.

• Journal of Ginseng Research
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• 제16권1호
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• pp.13-17
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• 1992

The present experiments were performed to investigate the effects of the ginseng total saponin on the development of physical dependence on morphine via intracerebroventricular (i.c.v) route. Morphine (10 $\mu\textrm{g}$/${mu}ell$/hr) was continuously infused via osmotic minipumps into lateral cerebral ventricle of male Sprague Dawley rats for 7 days. Concurrent ginseng total saponin (100, 200 $\mu\textrm{g}$/10${mu}ell$/hr) was infused intraperitoneally (i.p) via osmotic pumps for 7 days. Treatment with ginseng total saponin (200$\mu\textrm{g}$/10${mu}ell$/hr) significantly diminished jumping, teeth chattering, hypothermia and weight loss precipitated by naloxone, compared with those animals received only morphine infusion. These results suggest that ginseng total saponin has central effect on the inhibition of physical dependence on morphine, as systemic ginseng total saponin inhibits the development of physical dependence in rats infused with morphine intracerebroventricularly.