• Journal of Digital Convergence
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• v.18 no.8
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• pp.85-95
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• 2020

It is a newly defined concept of digital sex crimes as the sex crime pattern in Korea is integrated with digital technology. After examining the current status and response of digital sex crimes in Korea, legal and institutional gaps are identified.It is also aimed at drawing up appropriate responses to domestic situations compared to cases in major foreign countries. This study adopted the mode of literature research.It used related data from government agencies, various statistics and survey data, seminar data organized by the National Assembly office, women's organizations, and research reports. The ultimate goal is to derive the problem situation by analyzing the current system.The results of this study are to discuss digital sex crimes that are being expanded and reproduced by the development of digital media. It also points out that the legal vacuum caused by the law's failure to keep up with the law needs to be continued.Our conclusion is that we should actively accept best practices from abroad. In addition, it is necessary to create a community value in which all members of society become "monitors" in the recognition that they may be perpetrators or victims.

• Korean Journal of Clinical Pharmacy
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• v.9 no.2
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• pp.81-87
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• 1999

췌장이식의 성공률은 지난 10년 동안 상당히 상승되었다. International Pancreas Transplant Registry에 따르면 1995년 이래 미국에서만 매년 1,000건 이상의 췌장이식이 실시되고 있다. 장기이식후 나타나는 급성 거부반응은 이식 후 6개월 이내에 가장 높은 빈도수로 나타난다. 췌장이식환자에서는 신장을 이식한 것보다 두배나 높은 거부반응을 나타나며 이로 인한 입원율의 증가 항림프제(antilyinphocyte) 사용과 감염의 증가로 이환율이 높다. 더구나 Cyclosporine (CsA)을 기초로 한 면역억제제요법의 사용은 높은 급성 거부반응률(acute graft rejection)을 초래하여 이식한 장기의 조직손실이 문제가 되고 있다. 새로운 면역억제제인 Tacrolimus (FK506)의 사용은 이식환자에서의 거부반응을 감소시켜 생존율을 증가시키는 것으로 알려져 있다. Tacrolimus는 neutral macrolide로 cyclic peptide인 CsA과는 화학 구조는 매우 다르나 비슷한 면역억제 효과를 보인다. 하지만 Tacrolimus의 사용시 신경독성, 신독성, 특히 고혈당증의 발생률이 높아 일부 이식센터에서는 장기 이식 후에 사용하기를 꺼리기도 한다. 하지만 여러 연구논문에서 간과 신장 이식 후 급성 거부반응 예방에 Tacrolimus는 CsA에 비해 이점이 있는 결과를 발표하였다. 결과적으로, 현재 췌장이식 후 Tacrolimus를 기초로 한 면역억제의 효과에 대한 연구가 활발히 진행중이다. 따라서 본 연구에서는 1994-1996년 사이에 Tacrolimus 또는 CsA를 기초로 한 면역억제요법을 투여 받은 췌장이식환자 101명을 후향적으로 조사하여 Tacrolimus (n=54)와 CsA(n=57)의 급성 거부반응 예방 효과와 신부전 발생률을 비교하였다. 모든 환자는 항림프구 약물, Azathioprine, Prednisone을 이식 후 면역억제제로 투여 받았다 기준선으로부터 $20\%$ 이상의 혈청 creatinine의 상승이 있는 환자에서는 급성 신부전으로 정의하였고 신장생검법으로 거부반응을 진단하였다 Matched-pair analysis에 따르면 췌장이식환자의 6개월 생존율은 CsA군에서 $97\%$, Tacrolimus군에서 $96\%$로 별다른 차이가 없었으며 (p=0.57), 6개월간의 이식한 췌장의 보존율은 CsA군에서는 $88\%, Tacrolimus에서 $91\%$. 유의한 차이는 없었다(p=0.29). 췌장이식 후 6개월 동안 Tacrolimus의 사용은 생검으로 증명되는(biopsy-proven) 급성 거부반응의 발생빈도는 CsA보다 유의하게 낮았을 뿐만 아니라 (p<0.05) 거부반응 증상의 심각도 또한 감소시켰다 (p=0.03). 급성거부반응 발생빈도의 감소로 Tacrolimus군에서 antilymphocyte 치료가 유의하게 줄어들었다(p=0.01). CsA군에서 Tacrolimus보다 신부전의 발생률이 높았으나 통계학적 차이는 없었다. 췌장이식후의 최적의 면역억제요법의 결정하기 위해서는 향후 Tacrolimus와 CsA을 비교하는 전향적 무작위 연구가 필요하다.

• Journal of the Korea Concrete Institute
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• v.17 no.6 s.90
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• pp.955-962
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• 2005

Still no accurate theory exists for predicting ultimate shear strength of deep reinforced concrete beams because of the structural and material non-linearity after cracking. Currently, the load capacity assesment is performed for the upper structure of the bridges and containing non-reliability in the applications and results. The purpose in this study is to evaluate analytically the complex shear behaviors and normal strength for the reinforced concrete deep beams and to offer the accuracy load capacity assesment method based on the reliability theories. This paper presents a method for the load capacity assesment of reinforcement concrete deep beams using nonlinear finite element analysis. A computer program named RCAHEST (Reinforced Concrete Analysis in Higher Evaluation System Technology), for the analysis of reinforced concrete structures was used. Material non-linearity is taken Into account by comprising tensile, compressive and shear models of cracked concrete and a model of reinforcing steel. From the results, determine the reliability index for the failure base on the Euro Code. Then, calculate additional reduction coefficient to satisfy the goals from the reliability analysis. The proposed numerical method for the load capacity assesment of reinforced concrete deep beams is verified by comparison with the others methods.

• Journal of the Korea Concrete Institute
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• v.24 no.2
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• pp.147-156
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• 2012

In recent years, many high-rise buildings have been constructed in irregular structural system with inclined columns, which may have effect on the structural behavior of beam-column joints. Since the external load leads to shear and flexural forces on the inclined columns in different way from those on the conventional vertical columns, failure mode, resistant strength, and ductility capacity of the inclined column-beam joints may be different than those of the perpendicular beam-column joints. In this study, six RC inclined beam-column joint specimens were tested. The main parameter of the specimens was the angle between axes of the column and beam (90, 67.5, and 45 degree). Test results indicated that the structural behavior of conventional perpendicular beam-column joint was different to that of the inclined beam-column joints, due to different loading conditions between inclined and perpendicular beam-column joints. Both upper and lower columns of perpendicular beam-column joints were subjected to compressive force, while the upper and lower columns of the inclined beam-column joints were subjected to tensile and compressive forces, respectively.

• Sleep Medicine and Psychophysiology
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• v.14 no.1
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• pp.49-53
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• 2007

Mitochondrial myopathy is characterized by variable clinical manifestations from mild limb weakness to fatal respiratory failure and central nervous system sequela. But it is a rare event that sleep disordered breathing become a clue of diagnosis for mitochondrial myopathy. We report a case of a 21 year-old man who was diagnosed as mitochondrial myopathy during the investigation for the possible cause of chronic hypoventilation syndrome. Before being admitted to our hospital, he was suspected as having sleep apnea syndrome in another hospital. We re-evaluated the history, physical examination, laboratoy findings and polysomnography in detail. Severe hypoxemia was noted during REM sleep on nocturnal polysomnography and the diagnosis of mitochondrial myopathy was made by muscle biopsy in rectus abdominis muscle. We treated him with bilevel positive airway pressure therapy during sleep and it could reverse the hypoxemia during REM sleep. He could be discharged with improved condition and is being well with the use of this ventilatory assistance.

• Journal of the Korea Concrete Institute
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• v.29 no.1
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• pp.43-51
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• 2017

As per current seismic design codes, diagonally reinforced coupling beams are restricted to coupling beams having aspect ratio below 4. However, a grouped diagonally reinforcement detail makes distribution of steel bars in the beam much harder, furthermore it may result in poor construction quality. This paper describes the experimental results of concrete coupling beam reinforced with high-strength steel bars (SD500 & SD600 grades). In order to improve workability for fabricating coupling beams, a headed large diameter steel bar was used in this study. Two full-scale coupling beams were fabricated and tested with variables of reinforcement details and aspect ratio. To reflect real behavior characteristic of the beam coupling shear walls, a rigid steel frame system with linked joints was set on the reaction floor. As a test result, it was noted that cracking and yielding of reinforcement were initially progressed at the coupling beam-to-shear wall joint, and were progressed to the mid-span of the coupling beam, based on the steel strain and failure modes. It was found that the coupling beams have sufficient deformation capacity for drift ratio of shear wall corresponding to the design displacement in FEMA 450-1. In this study, the headed horizontal steel bar was also efficient for coupling beams to exhibit shear performance required by seismic design codes. For detailed design for coupling beam reinforced with high-strength steel, however, research about the effect of variable aspect ratios on the structural behavior of coupling beam is suggested.

• Journal of the Korean Geotechnical Society
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• v.32 no.11
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• pp.43-50
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• 2016

A reinforcement is required to ensure the structural safety in case of railway embankment excavation under railway load. A large diameter soil nailing with concrete wall is applied as the reinforcement method instead of the conventional soil nailing system. In this study, a series of 3 dimensional numerical analyses are performed to investigate the optimum reinforcement considering 15 different conditions based on the length, lateral spacing, diameter, and inclination of the reinforcement. The interface between soil nail and perimetric grout is considered by means of cohesion, stiffness and perimeter of the grout. 0.3 m of reinforcement diameter is assessed as the most appropriate based on the economical viewpoint though ground displacement decreases with the increase of diameter, however the difference of displacement is negligible between 0.4 m and 0.3 m of diameter. Surface settlement, lateral displacement of wall, and stress of reinforcement are calculated and economic viewpoint to reinforce embankment considered. Consequently, the optimum reinforcement conditions considering those factors are evaluated as 3 m in length, 0.3 m in diameter, 1.5 m in lateral spacing, and 10 degree of inclination angle in the case of 3 m of excavation depth. Additionally, inclined potential failure surface occurs with approximately 60 degrees from the end of nails and the surface settlement and wall lateral displacement are restrained successfully by the large diameter soil nailing, based on the result of shear strain rate.

• The Journal of the Acoustical Society of Korea
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• v.36 no.1
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• pp.30-38
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• 2017

In this paper, we propose an underwater acoustic sensor fault detection method for passive sonar systems. In general, a passive sonar system displays processed results of array signals obtained from tens of the acoustic sensors as a two-dimensional image such as displays for broadband or narrowband analysis. Since detection result display in the operation software is to display the accumulated result through the array signal processing, it is difficult to determine the possibility where signal may be contaminated by the fault or failure of a single channel sensor. In this paper, accordingly, we propose a detection method based on the analysis of RMSCR (Root Mean Square Crossing-Rate), and the processing techniques for the faulty sensors are analyzed. In order to evaluate the performance of the proposed method, the precision of detecting fault sensors is measured by using signals acquired from real array being operated in several coastal areas. Besides, we compare performance of fault processing techniques. From the experiments, it is shown that the proposed method works well in underwater environments with high average RMS, and mute (set to zero) shows the best performance with regard to fault processing techniques.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.27 no.6
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• pp.615-624
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• 2014

It has been well known the sloshing pressure has complex shape and various patterns. The pattern of sloshing pressure is variously characterized by the pressure amplitude, duration time and skewness. The structural response induced by the sloshing pressure is also affected by the pattern of sloshing pressure and the type of structural members. In order to understand the structural response by the perspective view of categorized pattern, it is more efficient to make simple sloshing pressure pattern than to reflect the complex pressure history. In this study, the sloshing pressures obtained by the small scale model test are simplified with respect to their duration and skewness. Dynamic analyses of Mark-III LNG CCS are then parametrically performed with the consideration of various types of sloshing impact. Meanwhile, the failure pressures given the duration and skewness are investigated after parametric calculations are conducted to investigate the effect of pressure parameters on the structural response.

• Clinical and Experimental Reproductive Medicine
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• v.25 no.1
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• pp.35-41
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• 1998

This study was carried out to investigate the development rates of human embryos co-cultured with cumulus cells to each blastocyst stage. Human zygotes were co-cultured on cumulus cell monolayer in YS medium supplemented with 20% hFF. On day 2, if patient had four or more "good" embryos (regular blastomeres without fragmentation), embryos were further cultured for 72hrs. Blastocysts on day 5 were classified into early blastocyst (ErB), early expanding blastocyst (EEB), middle expanding Blastocyst (MEB), and expanded blastocyst (EdB) on the basis of their morphological aspects of trophectoderm cells and blastocoele. Subsequently, maximum 3 of best blastocysts were transferred in 486 cycles. The results in this study were as follows: Patients who had four or more "good" embryos on day 2 were 498 persons, but patients whose embryos could not be transferred due to failure in development to the blastocyst stage on day 5 were 12 persons (2.4%). The development rate of embryos to the blastocyst stage was 58.2% (2,885/4,957) on day 5, and the rates that developed to the ErB, EEB, MEB, and EdB stage were 15.0% (743/4,957), 14.9% (739/4,957), 14.4% (714/ 4,957), and 13.9% (689/4,957), respectively. Total 1366 blastocysts were transferred in 486 cycles (mean number=2.81). The implantation rate and the ongoing implantation rate obtained by observing the number of G-sac and FHB were 29.9% (409/1,366) and 22.5% (308/1,366), respectively. The clinical pregnancy rate was 51.2% (249/486), and the ongoing pregnancy rate' was 39.1% (190/486). Among women showing ongoing pregnancy, women with singleton were 50% (95/190), women with twin were 37.9% (72/190), and women with triplet were 12.1% (23/190). Although triplet pregnancy rate in this study was high such as 12.1%, because many blastocysts with high viability were produced in our co-culture system using cumulus cells on day 5, we really believe that a multiple pregnancy except twin should not occur by selecting good embryos for maximum two blastocyst transfer. These results demonstrate that autologous cumulus cells may be used for the production of blastocysts with high developmental competence, and the use of autologous cumulus cells to be collected easily, and to be treated conveniently at OPU must be an effective means for obtaining high implantation and pregnancy rate.