• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 추계학술대회 논문집
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• pp.679-686
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• 2008

There has been an increasing demand of introducing innovative public transport modes meriting high flexibilities of a bus mode along with on-time accuracy and quality environment-friendliness of a rail mode, as it is considered to significantly contribute to reducing huge social expenditures on the traffic congestion and environmental pollution agenda, and to be an alternative solution to better the urban transport problems. In order to comply with the need, Seoul Municipal Government has recently decided to build up GRT system of a new concept in Nangok area in Seoul, the first in its kind in Korea. The concession has been awarded to Seoul Metro. This thesis will study and benchmark similar systems abroad under operation, and further review necessary requirements overall which would secure full readiness for the operation of Nangok GRT system.

• 농촌계획
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• 제20권1호
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• pp.147-159
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• 2014

This study aims to draw up a basic plan to construct an agricultural theme park in a farming city as a way of establishing its regional identity represented by "Three Whites". Sangju, Kyongsangbuk-do which is the subject area of the study has been well-known for "Three Whites (rice, silkworm cocoon and dried persimmon)." The purpose of the study is to take a closer look at the folk life and culture of Sangju and develop tourism resources to promote regional development and competitiveness of the city. This study was conducted in several phases in consideration of the characteristics of plan and design, on the basis of the theoretical review of agricultural tourism. In the first phase, planning conditions were analyzed as per development objectives. In the second phase, strategies and concepts were established for the theme park, based on which development methods were decided by phase and facility. Then, a preliminary review was conducted on functions and facilities to introduce to the theme park. In the third phase, a comprehensive plan was drawn up, which includes basic plans for respective parts. In consideration of the characteristics of the study, construction was not looked at in detail. The total size of land subject to the study is approx. $97,960m^2$, which was divided into four separate zones--Sambaek Cultural Experience Zone, Natural Observation & Experience Zone, Agricultural Life Experience Zone and other facilities zone--in order to connect facilities, functions and experience with the physical characteristics of the city, and separate space planning was conducted for each zone. The outcome of the study carries significance as an example of alternative tourism which considers regional characteristics, develops local resources and makes use of obsolete rural facilities, in what is called the eco-friendly development where nature and eco-system, landscape and culture, and recreation and leisure come together as one.

• IMMUNE NETWORK
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• 제4권1호
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• pp.1-6
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• 2004

Transplantation would be the only way to cure the end-stage organ failure involving heart, lung, liver, kidney and pancreas. The replacement of the parts of the body damaged to lose its function or lost to trauma must be a dream of human-being. Human history is replete with chimeras, from sphinxes to mermaids, making one wonder if the ancients might actually have dreamed of what now is called 'xenotransplantation'. In the 20th century, the transplantation of organs and tissues to cure disease has become a clinical reality. The development in the fields of surgical techniques, physiology and immunology attributed to the successful transplantation in human. In the center of the successful transplantation lies the progress in understanding the cellular and molecular biology of immune system which led to the development of immunosuppressive drugs and the invention of the concept of immunological tolerance. The mandatory side effects of immunosuppressive drugs including infection and cancer forced us to search alternative approaches along with the development of new immunosuppressive agents. Among the alternative approaches, the induction of a state of immunologic tolerance would be the most promising and the most generic applicability as a future therapy. Recent reports documenting long-term graft survival without immunosuppression suggest that tolerance-based therapies may become a clinical reality. Last year, we saw the epoch making success of overcoming hyperacute rejection in porcine to primate xenotransplantation which will lead porcine to human xenotransplantation to clinical reality. In this review, I dare to summarize the development of transplantation immunology from the perspective of history.

• 대한한의학회지
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• 제28권3호통권71호
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• pp.116-125
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• 2007

Objective : To overview the protocols of clinical acupuncture research on cancer in the USA. Methods : Using 'acupuncture' and 'cancer' as keyword search terms in Clinical Trials. gov, 28 clinical studies were found. Three studies by non-American institutions were excluded and 25 studies were analyzed. Analytic parameters were cancer condition, primary outcome, research institution, study design, and acupuncture intervention. Results : Breast cancer was the most frequent single condition in the searched protocols. Pain and quality of life were the primary outcomes in many studies. Memorial Sloan-Kettering Cancer Centerin New York has performed the largest number of acupuncture cancer studies. The majority of studies were randomized controlled trials with active controls or placebo/sham controls. Total enrollment varied between the range of 10 and 700 subjects and ages of these subjects were at least above 18 years old (except one protocol). Most protocols had strict exclusion criteria for acupuncture needling such as bleeding disorders, infection, heart disorder, and central nervous system disorder. Conclusions : Clinical acupuncture studies for cancer patients have focused on pain, quality of life, and side effects induced by anti-cancer therapies. Re-evaluation and cautions for strict exclusion criteria in foreign countries are required to perform multi-national acupuncture trials.

• 한국ITS학회 논문지
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• 제10권5호
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• pp.60-70
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• 2011

전기버스를 대상으로 교통-전력-시설 통합 정보통신 네트워크 통신방식을 선정하기 위하여 최신기술 동향과 정확성, 안정성, 경제성의 선정요인을 기준으로 차량위치검지 및 무선통신방식을 GPS, CDMA, WLAN 방식으로 설계한다. 또한, 효율적인 연계를 위하여 대안별 주요 특징을 검토하고, 방안별 기술적 난이도와 정책적 행정적 난이도 및 비용타당성의 선정요인을 기준으로 Spoke & Hub 연계방식, 즉, 교통융합충전센터와 교통센터, 스마트 그리드센터를 각각 연계토록 연계방안을 수립한다.

• 대한기계학회논문집B
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• 제33권5호
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• pp.299-310
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• 2009

Fuel cells are expected to be promising future power sources in both aspects of thermal efficiency and environmental friendliness. Accordingly, worldwide research and development efforts have been enormously increasing recently in various applications such as power plants, transportation and portable power sources. Among others, high temperature fuel cells, such as solid oxide fuel cells and molten carbonate fuel cells, are suitable for electric power plants. Moreover, their high operating temperature is quite appropriate to construct further advanced integrated systems. This paper reviews recent literatures on research and development of integrated power generation systems based on high temperature fuel cells. Research and development efforts are summarized in the area of fuel cell/ gas turbine hybrid systems, application of carbon capture technology to fuel cell systems, integration of coal gasification with fuel cells, and the use of alternative fuels.

• 경영과정보연구
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• 제3권
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• pp.257-285
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• 1999

Korea Postal Service(KPS) nowadays lies in competitive environment with alternative business such as door-to-door delivery service. Customers began to complain about postal service quality and ask the government to reform a public firm through management innovation. But, Korea Postal Service has not met the break-even point between it's revenue and expenditure because the service is under the government system and cannot independently make major decisions on products, pricing, services, personnel management, financial policies and etc. The objective of this study is to provide marketing planners and practitioners with some guidelines when they establish marketing strategies and to help marketers on theories and practical instructions about postal service marketing when they interact with customers. I. A field survey on both customer satisfaction and internal staff satisfaction was conducted to get some ideas for the marketing strategy planning. II. Practical guidelines and instructions were made for marketers to communicate with customers in various areas such as pricing, product, service demand, marketing channel, promotion, and etc. III. Some suggestions on marketing policies for planners and mangers in the marketing strategy were described including personnel resource as well as physical resource. IV. Special issues on small packet market and direct mail market were discussed and some alternative solutions were proposed. V. Database marketing strategy was emphasized to get new business opportunities such as direct mail, and to provide differential services to customers as much as their contribution into the profitability for KPS. VI. Cyber Post Office should be constructed on Internet to provide new services which are combined with physical material flow and information technologies.

• 통상정보연구
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• 제14권2호
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• pp.81-119
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• 2012

본 연구에서는 유통경로 상의 지배구조 유형이 기업성과에 미치는 영향에 대해 실증적으로 검증해 보았다. 수출유통의 성과를 극대화 하기위한 일반적 전략대안은 수직적 통합에 의한 성과관리이다. 그러나 수출유통에 있어서 소유구조에 의한 수직적 통합은 용이하지 않은 경우가 대부분이다. 본 연구의 결과, 소유구조 이외에도 다양한 관계전략으로 유통성과 관리가 가능하다는 것을 알 수 있었다. 본 연구의 전략적 시사점으로, 수출유통경로결정에 있어서, 소유구조이외에도 거래관계구조 상의 정보교류, 협력관계, 신뢰관계 확립 등을 통하여 유통경로의 수직적 통합과 같은 수준의 성과를 이루어 낼 수 있다는 것을 제시할 수 있다.

• BMB Reports
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• 제55권1호
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• pp.39-47
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• 2022

Adoptive cell transfer (ACT), a form of cell-based immunotherapy that eliminates cancer by restoring and strengthening the body's immune system, has revolutionized cancer treatment. ACT entails intravenous transfer of either tumor-resident or peripheral blood-modified immune cells into cancer patients to mediate anti-tumor response. Although these immune cells control and eradicate cancer via enhanced cytotoxicity against specific tumor antigens, several side effects have been frequently reported in clinical trials. Recently, exosomes, potential cell-free therapeutics, have emerged as an alternative to cell-based immunotherapies, due to their higher stability under same storage condition, lower risk of GvHD and CRS, and higher resistance to immunosuppressive tumor microenvironment. Exosomes, which are nano-sized lipid vesicles, are secreted by living cells, including immune cells. Exosomes contain proteins, lipids, and nucleic acids, and the functional role of each exosome is determined by the specific cargo derived from parental cells. Exosomes derived from cytotoxic effectors including T cells and NK cells exert anti-tumor effects via proteins such as granzyme B and FasL. In this mini-review, we describe the current understanding of the ACT and immune cell-derived exosomes and discuss the limitations of ACT and the opportunities for immune cell-derived exosomes as immune therapies.

• 대한조선학회논문집
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• 제61권3호
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• pp.185-199
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• 2024

Global warming impacts every corner of human life. Maritime transportation and shipbuilding industries are no exception. Recent counteraction in maritime industries is accelerating to meet the zero emission by 2050. Various alternative energy sources have been studied, and recent developments in Europe show that the windship, as a proven technology, can be an attractive candidate to solve the problem. In this paper, as the alternative transportation option, to infer the performances of modern windships, the non-dimensional ratios of past tall ships and windships are studied and reviewed. In addition, the ratios are compared to estimate the position of current and future windships under consideration. It is found that regarding the ratio distributions, the current windships being planned can be either wind-assisted propulsion ships or less fully functional windships than the past tall ships.