• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7153-7158
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• 2014

Background: Non-Hodgkin's lymphoma (NHL) patients demonstrate multiple symptoms in diagnosis and treatment processes. This cross-sectional descriptive study aimed to determine the symptoms and symptom clusters in such patients receiving chemotherapy. Materials and Methods: The study was carried out on a total of 110 inpatients and outpatients receiving treatment in 7 hospitals in Ankara, Turkey. A questionnaire form and the Memorial Symptom Assessment Scale (MSAS) were applied. Percentages, means, t test, one way analysis of variance (ANOVA) and cluster analysis were used for statistical analyses. Results: The most prevalent symptoms in this study were lack of energy, hair loss and change in the way food tastes. The most severe symptoms were hair loss, change in the way food tastes and constipation. The top three most distressing symptoms were taste change, constipation and mouth sores. Seven symptom clusters were determined in this study. Conclusions: Findings of the study will provide an understanding of symptom experiences of Non-Hodgkin's lymphoma patients receiving chemotherapy and will guide determining appropriate nursing interventions. Receiving care of desired quality will contribute to increasing quality of life of affected individuals.

• 임상간호연구
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• 제14권1호
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• pp.61-70
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• 2008

Purpose: Women with gynecologic cancer often experience various physical and psychological symptoms relating to the cancer and its treatment. The purpose of this study was to identify symptom clusters. Method: A survey was conducted on 184 women with diagnoses of cervical, ovarian or endometrial cancer. Fifty symptoms were assessed for prevalence, severity and interference, and symptom clusters were identified. Cluster analysis was done using SPSS version 12.0. Results: Fatigue was identified as the most prevalent symptom (81.52%), lack of vaginal lubrication (2.26) as the most severe symptom, and lack of vaginal lubrication as the most interfering one (2.15). Identified six clusters were: Anorexia-pain cluster (loss of appetite, taste change, weight loss, appearance change, alopecia, weakness, pain), Fatigue cluster (lack of concentration, lack of memory, fatigue, dry mouth), Urinary-bowel distress cluster (urinary difficulty, constipation), Abdominal discomfort cluster (lower abdominal pain, abdominal pain, bloating), Emotional distress (sadness, anxiety-worry, nervousness, restlessness), and Menopausal cluster (sweating, hot flush, fever). Conclusion: The result of this study provides fundamental data to health care professionals in developing interventions for effective symptom management for women with gynecologic cancer by understanding identified 6 symptom clusters.

• 성인간호학회지
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• 제14권3호
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• pp.411-417
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• 2002

Purpose: This study was to investigate symptom occurrence related to the disease characteristics of patients with cancer. Method: A total of 301 patients with cancer participated in this study. The participants were recruited from University Hospitals located in Seoul, Wonju, Kwangju, Daegu, and Pusan. Data collection was performed by using a questionnaire on symptom occurrence. The obtained data was analyzed using SPSS computer program that included descriptive statistics, Pearson correlation, one-way ANOVA, and t-test. Result: The mean score of fatigue was the highest (3.24), followed by loss of appetite, lack of concentration, change in appearance, pain, insomnia, change in bowel pattern, nausea/vomiting, coughing, and dyspnea. Most symptoms were significantly correlated with each other. The level of symptom occurrence in patients with lung cancer or cervix cancer was significantly higher than the level in patients with stomach cancer. Patients receiving radiation therapy or a combined therapy of radiation therapy and chemotherapy experienced significantly higher level of symptom occurrence than those receiving chemotherapy only. Also, female patients experienced higher level of symptom occurrence than male patients did. Conclusion: The sites of cancer, types of treatment, and gender influence the level of symptom occurrence of patients with cancer. Thus, these variables should be considered when assessing and planing for symptom occurrence of patients with cancer.

• 생물정신의학
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• 제2권1호
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• pp.91-99
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• 1995

A on-off study was designed to evaluate the effects of addition of transdermal esrtradiol to tricyclic antidepressants on depression level, vasomotor symptom(hot flush), sexual functions and hormonal status, plasma 5-hydroxyindoleascetic acid(5-HIAA) level in postmenopausal women with depression. Plasma level of estradiol, progesterone, LH, FSH, prolactin and 5-HIAA was measured by Time-resolved fluoroimmunoassay and HPLC(High Performance Liquid Chromatography). To asses their symptoms, the BDI(Beck Depression Inventory) and modified symptom scale, extracted from women's health questionnaire were used. Depression score, sexual function score were decreased by the last 4-weeks of addition of transdermal estradiol to antidepressant treatment, not Significant, but vasomotor symptom (hot flushes) score was decreased significantly(p<0.05) by the last 4-weeks of the given treatment. Thus, during addition of transdermal estradiol to antidepressants treatment, only vasomotor symptom(hot flushes) was improved significantly, but depression level was not changed in postmenopausal women with depression. Plasma FSH, estradiol and prolactin level was not changed in postmenopausal women with depression. Plasma FSH, estradiol and prolactin levels were increased by the last 4-weeks of the treatment. There were not significant correlations between clinical symptoms and plasma hormonal status and 5-HIAA level in baseline. After the last 4-weeks of transdermal estradiol treatment, the change of depression score was correlated significantly with change of serum prolactin and 5-HIAA level and the change of vasomotor symptom score was correlated significantly with the change of plasma prolactin level.

• 사상체질의학회지
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• 제13권3호
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• pp.114-117
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• 2001

1. Object: The primary purpose of this case study is to report that a Tae-Yin-In patients with sweaty scrotum and dysuria was treated with 'Chung sim youn ja tang' and then his symptom decreased 2. Subject: A male obese patient with sweaty scrotum and dysuria that visit Kirin oriental hospital to be treated for obesity 3. Method: The patient was to have a very low calory diet and to exercise for an hour daily and to take a Herb-medicine, 'Chung sim youn ja tang'. Change of his subjective symptom, sweaty scrotum and dysuria, was measured by VAS(Visual Analog Scale) 4. Result: A Tae-Yin-In patients with sweaty scrotum and dysuria was treated with 'Chung sim youn ja tang' and Change of his subjective symptom, sweaty scrotum and dysuria, was measured by VAS(Visual Analog Scale) then his symptom decreased. 5. Conclusion: 'Chung sim youn ja tang' may have an effect on Treatment of sweaty scrotum and dysuria. Further study is needed how to conclud 'disease pattern of constitution' accroding with co-symptom.

• 성인간호학회지
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• 제17권2호
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• pp.248-258
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• 2005

Purpose: The purpose of this study is to examine the factors influencing symptom experience in patients with liver cirrhosis(LC). Method: A descriptive correlational study design was used. A convenience sample of 129 subjects was recruited from the gastroenterology department at two university hospitals in Seoul, Korea. Symptom experience in LC was measured with the instrument developed by the researcher based on Theory of Unpleasant Symptoms(Lenz et al, 1995) and the Child-Pugh Score, the Korean version of Profile of Mood States, and the Family Support Questionnaire were used to identify the factors influencing symptom experience. Results: The mean score of symptom experience was relatively low(M=41.67, SD= 24.71). Among individual symptoms, fatigue had the highest score in all dimensions. Fatigue, abdominal distension and/or peripheral edema, muscle cramps, dry mouth, and change in appearance were explored as symptoms needing management. In the regression analysis, symptom experience was found to be influenced significantly by anxiety/depression($R^2=.418$, p=.000) and the severity of LC(Child-Pugh Score)($R^2=.125$, p=.000). These variables explained 54.3% of the variance in symptom experience(F=63.607. p=.000). Conclusion: It suggests that nurses need to take into consideration psychological factor as well as physiological factor in symptom management for patients with LC.

• 한국보건간호학회지
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• 제35권1호
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• pp.120-134
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• 2021

Purpose: The reproductive health of women in early adulthood can affect pregnancy, childbirth, and menopause in later life. Menstrual symptoms not only affect daily life, but are also a reflection of a woman's reproductive health. This study was conducted to explore the factors affecting menstrual symptoms among university students. Methods: The general characteristics, life style, menstrual characteristics, stress, and menstrual symptom of 177 female students were assessed through an online survey at one university. An independent sample t-test, one-way variance analysis, correlation analysis, and multiple regression analysis were performed using the SPSS 22.0 program. Results: The menstrual symptom score was 91.68±32.11 points, and the score of 'mood change' was the highest. Stress (��=.38, p<.001), amount of menstruation (��=.20, p=.001), menarche age (��=-.18, p=.003), health problems (��=.16, p=.010), and age (��=.15, p=.016) were found to have a significant effect on menstrual symptom, and the explanatory power of the regression model was 40%. Conclusion: This study investigated the degree and influencing factors of menstrual symptom using the Korean Menstrual Symptom Scale (KMSS) developed for Korean university students. Among the factors influencing menstrual symptom, stress appeared to play a significant role. Stress management, observation of menstrual characteristics, and general health care are necessary to maintain a woman's reproductive health.

• 한방안이비인후피부과학회지
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• 제28권3호
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• pp.161-172
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• 2015

Objective: The purpose of this study is to report the effectiveness of Sihochunggan-tang gagambang in the four patients with eczema ongroin, inner thigh.Methods: This case study was conducted for four groin, inner thigh eczema patients who have visited Korean Medicine Clinic. Sihochunggan-tang gagambang was prescribed to all four patients and evaluated the symptom change through photographs and two assessment methods. The assessment methods are Atopic Dermatitis Severity Index(ADSI) and Visual Analogue Scale(VAS). ADSI was used to evaluate the objective symptom change and VAS was used to evaluate the subjective symptom change.Results & Conclusion: The ADSI and VAS were decreased compared to the first in all four patients in our study. And most symptoms of four patients were improved. As a result of examining ADSI, VAS scores and photographs, Sihochunggan-tang gagambang can be effective on the groin, inner thigh eczema in four cases in our study.

• 한국노년학
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• 제29권4호
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• pp.1611-1628
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• 2009

건강상태와 심리사회적 요인이 우울증상과 밀접한 관련이 있다는 것은 기존연구를 통하여 널리 알려진 사실이다. 하지만 기존의 종단데이터 부족과 분석방법의 한계로 이러한 변수들과 우울증상 궤적과의 관계에 대해서는 알려진 바가 많지 않다. 이러한 기존 연구의 한계를 염두에 두고, 본 연구는 건강상태 및 심리사회적 요인과 우울증상의 궤적간의 관계를 살펴보는 것을 주 목적으로 한다. 본 연구는 전국 대표샘플인 한국복지패널데이터 1, 2, 3차 자료를 이용하여 60세 이상의 노인들(N=4,919)의 우울궤적 예측요인을 잠재성장모형을 이용하여 분석하였다. 사회경제적 변수를 통제한 상태에서 건강변수와 심리사회적 변수들이 우울궤적에 미치는 영향은 기존연구와 유사한 점도 있지만 다른 점도 있는 것으로 나타났다. 구체적으로 건강변수는 우울증상의 수준에는 영향을 미치지만 우울증상의 변화속도에는 영향을 미치지 않는 것으로 나타났다. 반면 심리사회적 변수는 기존 연구와 동일하게 모두 우울수준에 영향을 미치지만, 기존 연구와는 다르게 변수에 따라서 우울증상의 변화속도에 미치는 영향은 상이한 것으로 나타났다. 즉, 자아존중감과 가족관계 변수는 우울증상 변화속도에 긍정적 영향을 미치는 반면, 사회적 관계는 우울증상 변화속도에 부정적 영향을 미치는 것으로 나타났다. 이러한 연구결과를 토대로 실천 및 향후 연구를 위한 함의를 논의하였다.

• 여성건강간호학회지
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• 제24권4호
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• pp.414-422
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• 2018

Purpose: To develop Korean Menstrual Symptom Scale (KMSS) for university students and test its reliability and validity. Methods: The scale was developed by intensive literature review, development of preliminary items, verification of content validity, development of secondary items, verification of construct validity, and extraction of final items. Thirty-nine items were constructed. Data for validity and reliability testing were collected with a questionnaire survey from 391 university students. Data were analyzed with descriptive statistics, factor analysis, and reliability coefficients (Cronbach's ${\alpha}$) with the SPSS program. Results: There were 37 final items which were sorted into six factors: 'negative affection (8 items)', 'change of activity level (7 items)', 'physical symptom (9 items)', 'mood change (9 items)', 'change in concentration level (4 items)', and 'body water retention (5 items)'. The cumulative percent of variance was 63.3%. Regarding the reliability of the scale, its Cronbach's ${\alpha}$ was 0.96. Cronbach's ${\alpha}$ values for these factors ranged from 0.75 to 0.91. Conclusion: The KMSS demonstrated acceptable validity and reliability. Repeated research is needed to measure menstrual symptom experienced by women of variable ages.