• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.9 no.6
• /
• pp.1806-1810
• /
• 2008

Thirty five AD patients were treated with Phellinus linteus grown in germinated brown rice(PB) p.o., at 6, 9, and 12 g/day to the patients with their body weight for 12 weeks. A significant reduction in mean severity scores and mean symptom scores was observed after PB treatment. The mean SCORAD indices pre and post PB treatment were $31.28{\pm}10.01$ and $22.39{\pm}15.59$ (p<0.05), respectively. And the mean symptom score of pruritus assessment decreased from $7.37{\pm}1.33$ to $4.6{\pm}2.34$ (p<0.05) after PB treatment. These results suggest that PB shows alleviation of atopic dermatitis symptoms.

• Journal of Yeungnam Medical Science
• /
• v.39 no.3
• /
• pp.181-189
• /
• 2022

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative condition characterized by loss of motor neurons, resulting in motor weakness of the limbs and/or bulbar muscles. Pain is a prevalent but neglected symptom of ALS, and it has a significant negative impact on the quality of life of patients and their caregivers. This review outlines the epidemiology, clinical characteristics, underlying mechanisms, and management strategies of pain in ALS to improve clinical practice and patient outcomes related to pain. Pain is a prevalent symptom among patients with ALS, with a variable reported prevalence. It may occur at any stage of the disease and can involve any part of the body without a specific pattern. Primary pain includes neuropathic pain and pain from spasticity or cramps, while secondary pain is mainly nociceptive, occurring with the progression of muscle weakness and atrophy, prolonged immobility causing degenerative changes in joints and connective tissue, and long-term home mechanical ventilation. Prior to treatment, the exact patterns and causes of pain must first be identified, and the treatment should be tailored to each patient. Treatment options can be classified into pharmacological treatments, including nonsteroidal anti-inflammatory drugs, antiepileptic drugs, drugs for cramps or spasticity, and opioid; and nonpharmacological treatments, including positioning, splints, joint injections, and physical therapy. The development of standardized and specific assessment tools for pain-specific to ALS is required, as are further studies on treatments to reduce pain, diminish suffering, and improve the quality of life of patients with ALS.

• Mood & Emotion
• /
• v.10 no.1
• /
• pp.31-36
• /
• 2012

Objectives : The aim of this study was to investigate the relationship between depressive symptom, spiritual well-being and state hope in early adults and middle aged patients with depression. Methods : A total of 180 outpatient were surveyed with Beck Depression Inventory (BDI), Functional Assessment of Chronic Illness Therapy-Spiritual Well-being Scale (FACIT-Sp) and The State Hope Scale (SHS). Mean scores of BDI, FACIT-Sp and SHS were compared between two groups of different age. Correlation analysis and multiple linear regression analyses were performed to identify the effect of BDI and FACIT on SHS according to age. Results : Mean scores of SHS and FACIT were higher significantly in middle aged group than early adults group, while BDI was not different between two groups. And early adults and middle aged patient's state hope showed a significantly negative correlation with spiritual well-being. In regression analysis, the effect of BDI, FACIT on SHS were significant in both groups and the regression model explained 42% of the variance of state hope in early adults group and 26% in middle aged group, respectively. Conclusion : These findings suggest that in depressive symptom and low state hope relationship, spirituality is important protective factor in both aged adult outpatients with depression.

• Journal of Korean Academy of Nursing
• /
• v.45 no.4
• /
• pp.604-612
• /
• 2015

Purpose: The purpose of this study was to investigate the levels of physical symptoms, anxiety, depression, and quality of life (QOL) during chemotherapy for colorectal cancer patients in South Korea and to identify factors influencing their QOL. Methods: Data were collected from 144 colorectal cancer patients receiving chemotherapy during 2012 at one general hospital located in Seoul. Physical symptoms were measured by the M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module, and anxiety and depression were measured by the Hospital Anxiety Depression Scale. QOL was measured by the Functional Assessment of Cancer Therapy-Colorectal. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, $Scheff{\acute{e}}$ post hoc test, Pearson correlation and stepwise multiple regression. Results: Mean age of the participants was 56.6 and most of them were not employed. In terms of cancer stage, 38.2% were in stage 3, followed by stage 4 (34.7%). The most frequent symptom was lack of appetite, followed by sleep disturbance and fatigue. The mean score for anxiety was 5.40 with a prevalence of 23% and that of depression 8.85 with a prevalence of 64.6%. The mean score for quality of life was 81.93 out of 136 and 75.3% of the variance in QOL was explained by depression, symptoms, anxiety, treatment place, and occupational status. Depression was the strongest predictive factor. Conclusion: Oncology professionals need to pay special attention to relieving depression as well as physical symptoms to improve QOL during chemotherapy for colorectal cancer patients.

• Research in Community and Public Health Nursing
• /
• v.19 no.3
• /
• pp.378-387
• /
• 2008

Purpose: The purposes of this study were to investigate factors related to the depression of the elderly dwelling in a big city, and to explore the influence of physical health, cognitive symptom and nutritional status on the elders' depression. Methods: After the approval of the Institutional Review Board (IRB) and obtaining the participants' consent form, a face to face and private interview was conducted with each participant from Mar, 2007 to Aug, 2007 by trained graduate level students. A total of 201 elders aged over 65 years participated in the study. The questionnaire consisted of K GDS, PHQ 15 and Nutritional Screening Initiative (NSI). Collected data were analyzed with the SPSS 13.0 program, which was used for frequency, percentage, mean, standard deviation, Pearson correlation coefficients, and multiple regression. Results: The major findings of this study were as follows. 1) 28.4% of the subjects belonged to the depression group, 78.1% had one or more diseases, 85.6% had experienced somatic symptoms, and 49.7% belonged to the nutritional risk group. 2) Older age, lower educational level, more pocket money a larger number of diseases, more severe cognitive symptoms and poorer nutritional status were significantly related to a higher depression score. 3) Significant factors influencing depression were nutritional status, cognitive symptoms and the number of diseases, which explained 38.1% of the variance of elderly depression, and nutritional status was the most influencing factor. Conclusion: The finding of this study gives useful information for developing assessment tools and interventions for elders' depression.

• The Journal of Korean Medicine
• /
• v.25 no.1
• /
• pp.198-204
• /
• 2004

Backgrounds & Methods : Asthma is considered to be chronic inflammatory disease characterized by airway hyperresponsiveness and pulmonary eosinophilia. Recently, there has been many researches about asthma. IBS(Irritable Bowel Syndrome), PUD(peptic Ulcer disease) and GERD(gastroesophageal reflux disease) are the most common diseases of the gastrointestinal tract. Recent studies suggest that IBS, PUD and GERD are associated with bronchial hyper-responsiveness and bronchial asthma might be more prevalent in IBS and GERD patients than in control subjects. In addition, there are many comments about the interrelationship between the gastrointestinal problem and asthma in the oriental medical books. Actually, many oriental medical doctors don$^{\circ}$Øt consider the gastrointestinal condition when they deal with the asthmatic patients these days. So, we assessed the prevalence of gastrointestinal symptoms and histories in a cohort of patients with asthmatic symptoms. We evaluated 128 outpatients with asthmatic symptoms(60 males and 68 females, aged 13-75). All subjects enrolled completed the GSRS(Gastrointestinal Symptom Rating Scale). GSRS is an interview based rating scale consisting of 15 items for assessment of gastrointestinal symptoms in IBS and PUD developed by Jan Svedlund. Results : The limit of total score of GSRS in asthmatic patients is zero to 30. The number of patients with no GI symptoms is 66(51.5%). The number of patients with GSRS>5 is 62(48.4%), GSRS>10 is 24(18.8%), GSRS>15 is 8(6.25%). The number of patients with history of gastritis is 54(42.2%), gastric ulcer is 13(10.2%), gastroptosis is 8(6.25%), IBS is 6(4.68%), others is 6(4.68%). Conclusions : This study suggests that patients with bronchial asthma have an significant prevalence of gastrointestinal symptoms. Additional studies are needed to find the mechanism of the association between gastrointestinal symptoms and asthma.

• Journal of the Ergonomics Society of Korea
• /
• v.32 no.6
• /
• pp.495-501
• /
• 2013

Objective: The purpose of this study was to survey of the subjective health status of the elderly farmer. Background: With increase of aged population, the health of the elderly farmer has become main concerns of the elderly in the rural community. For the effects of the factors related to quality of life, subjective health condition showed the largest influence. Method: The survey was conducted by 326 elderly farmers aged 50 and older in rural areas through structured questionnaires. Survey questionnaire consisted items of general characteristics, health-related life habits, levels of stress(SF-PWI), symptom of musculoskeletal diseases and general level of health(SF-36). For the data analysis, SPSS 19.0K was used, and analysis was conducted by using frequency, percentage, mean, and standard deviation. For the symptom prevalence of musculoskeletal disorders and comparison of average level of health, chi-square test and t-test were used. Results: The results of the study are as follows. It was shown that the symptom prevalence of musculoskeletal disorders had a significant difference in gender (p<0.01). Frequency analysis on presence of musculoskeletal symptoms in each part of body showed that leg/knee region was 28.1%, back region was 26.6%, shoulder region was 18.0%, arm/elbow region was 11.9%, hand/wrist region was 8.2% and neck region was 7.2%. According to comparison of average level of health, a social functioning were the highest as score 87.3, followed by mental health(65.6) and role limitation-emotional(65.5). Conclusion: Health promotion program for the elderly and female in the rural are needed. Application: The survey of the subjective health status of the elderly should be used for planning factors to make a health improvement plan in elderly farmer.

• The Journal of Churna Manual Medicine for Spine and Nerves
• /
• v.4 no.1
• /
• pp.65-73
• /
• 2009

Objectives : The propose of this study is to analyze characteristics with sex, age, motivation, symptom, Impression, treatment effect about temporomandibular disorder patients. Method : We performed a retrospective study of 52 patients who visited the Jaseng Hospital of Oriental Medicine, from August 2008 to October 2008. Result : Women occupied the most part. And 27 persons in the 20th are the most distribution of age. The majority of patients occured the symptom for no reason. In the distribution of symptoms, TMD pain(88.46%), Click sound(82.69%), neck pain(52.92%), headache(38.46%), lumbago(21.15%) happened. In the impression through radiological diagnoses, The majority of patients diagnosed Straightening of cervical lordotic curvature. Oriental medical treatment showed a very valuable effect on improvement of TMD symptom. Conclusion : The results showed a valuable treatment effect of temporotandibular disorders on Oriental medical treatment. Therefore this work have the necessity of continuous study and observation and will help us to understand the features of patients who visiting the TMD clinic of Jaseng Hospital of Oriental medicine.

• Quality Improvement in Health Care
• /
• v.5 no.1
• /
• pp.120-127
• /
• 1998

Background : This study is to identify preoperative patient characteristics associated with a lack of improvement on one or more measures peri operatively, postoperative 3-4 months, and postoperative 12 months. Methods : For the assessment, prospective study was performed with 92 patients who had undergone either one eye or both eye cataract surgery by 3 ophthalmologists practicing at a university hospital. The criteria of improvement were (1) Snellen visual acuity, (2) a cataract-related symptom score(possible range: 0, 0 of 6 symptoms present or bothersome, to 18, all 6 symptoms very bothersome), and (3) VF-14 score - a measure of functional impairment in patient with cataract - (possible range: 0, inability to perform any of the applicable activities, to 100, no difficulty in performing any of the applicable activities). Results : Although 14 patients (15.2%) failed to improve on one or more of the outcome measures assessed, no one failed to improve on all three measures. Both eyes of surgery than one eye, preoperative cataract symptom score of 1-4, 5 or higher than 0 were associated independently with the increased likelihood of improvement (odds ratio 8.95, 7.16, 8.87 respectively). And the preoperative level of Snellen visual acuity was not associated with the likelihood of improvement Conclusion : We conclude that specific preoperative characteristics (both eyes, cataract symptom score) are independent predictors of patient outcome after cataract surgery.

• Journal of Oral Medicine and Pain
• /
• v.44 no.1
• /
• pp.16-24
• /
• 2019

Purpose: The purpose of this study was to assess the association of personality characteristics with temporomandibular disorders (TMDs). Methods: Four hundred and fifty one college students in Gyeonggi-do completed the revised version of the Minnesota Multiphasic Personality Inventory (MMPI-2) and a questionnaire and collected data were analyzed by IBM SPSS Statistics ver. 25.0 software (IBM Co., Armonk, NY, USA). Results: Mean values of the number of positive answers of TMD symptoms were significantly higher in higher scorers on hypochondriasis (Hs), depression (D), paranoia (Pa) (Hs>60, D>64, Pa>59) (p<0.01). Higher scorers on Hs, hysteria (Hy), schizophrenia (Sc), Pa, psychasthenia (Pt) (Hy>64, Sc>64, Pt>64) exhibited significantly higher mean values of the number of positive answers of contributing factors for TMD (p<0.01, p<0.001). Low scorers on social introversion ($Si{\leq}44$) exhibited significantly lower mean value of the number of positive answers of contributing factors for TMD than high or moderate scorers on Si (Si>64, 45-64) (p<0.01, p<0.05). The percentage of subjects who responded that they had at least one TMD symptom was significantly higher in higher scorers on Hs, Pt, D (p<0.05, p<0.01). The significantly higher percentage of higher scorers on D, Pa reported at least one contributing factor for TMD (p<0.05). The percentage of subjects who responded that they had at least one TMD symptom or one contributing factor for TMD was significantly different among three groups divided by T-score on Si (p<0.01, p<0.05). T-scores of Hs, D, Hy, Pt and Sc showed significant correlation with the numbers of TMD symptoms and contributing factors for TMD, respectively (p<0.001). A correlation was found between T-score of Pd and the number of TMD symptoms (p<0.001). T-score of Si correlated to the number of contributing factors for TMD (p<0.001). Conclusions: Most clinical scales of MMPI-2 were found to be related to TMD. Psychological assessment including MMPI-2 may play a role in predicting treatment outcome and planning treatment of TMD.