• Title/Summary/Keyword: Sustained

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A Study of Acoustic Characteristics of Two Syllables Words and Sustained Vowel (병적음성에 대한 지속 모음 및 이음절어 발화시 나타나는 음향학적 차이에 대한 연구)

  • 채윤정;김범규;홍기환
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.11 no.1
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    • pp.104-112
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    • 2000
  • An evaluation of voice disorder has two methods. One is a perceptual analysis and the other is an acoustic analysis. All of these methods are just focused on sustained vowel. The analysis of conversational speech levels in voice disorder has not been achieved enough. The purpose of the present study is to compare two syllable words and sustained vowel in the vocal polyp patients and normal male speakers and to be applied on the vocal assessment and the voice therapy as a basic data. fifteen male patients with vocal polyp were the subject group. Fifteen healthy male were the control group for this study. The voices of the subject and control group, saved in MDVP of CSL were analyzed by its own analysis program. As a results, in subject group, the voice qualities between the vowel following lenis stop and the sustained vowel had no differences, and the voice qualities were different significantly between the vowel following heavily aspirated stop and the sustained vowel. In the control group the vowel fllowing stops and sustained vowel had also many differences in their voice quality, especially significant between the vowel following glottal stop and e sustained vowel.

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EMG Power Spectral Analysis on Masticatory Muscle Fatigue in Chronic Muscle Pain Patients (근전도 power spectrum을 이용한 만성근육동통 환자에 있어서의 저작근 피로에 관한 연구)

  • 이채훈;김영구;임형순
    • Journal of Oral Medicine and Pain
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    • v.22 no.1
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    • pp.145-155
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    • 1997
  • The purpose of this study was to compare differences in endurance time and EMG power spectral characteristics of the masticatory muscles during sustained isometric contraction between patients and controls. 15 CMD patients{8 women and 7 men, aged 15 to 38 years(24.1$\pm$7.5)}, and 15 healthy volunteers{8 women and 7 men, aged 15 to 30 years(24.7$\pm$3.4)} without past history or present symptoms of CMD were included in this study. Sustained isometric contractions of masticatory muscles were perfomeed as long as possible at 50% level of maximum voluntary contraction(MVC) of EMG activity via visual feedback, and the duration of sustained isometric contraction(endurance time) was examined. The author perfomed EMG power spectral analysis in the myoelectric signals of masseter and anterior temporal muscle during sustained isometric contraction in CMD patients with chronic muscle pain and healthy controls. The author came to following conclusions from the results. 1. The endurance time of the patient group was shorter than the control group in sustained isometric contraction of masticatory muscles(p<0.01). 2. MF values of masticatory muscles with sustained isometric contraction during endurance time were decreased following regression line in both groups(p<0.01, r>0.9). 3. The amount of MF shift to lower frequency range exhibited no significant differences between the patients and the control group in sustained isometric contraction during endurance time. 4. SMF to lower frequency range of the patient group was steeper than the control group in sustained isometric contraction during endurance time(p<0.05).

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Efficacy test of sustained-release somatotropin by implantation in steer, cow and barrow (비육우, 젖소 및 비육돈에서 이식형 소마토트로핀 지속성 제형의 유효성 시험 연구)

  • Kim, Nam Joong
    • Korean Journal of Veterinary Research
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    • v.51 no.1
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    • pp.1-6
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    • 2011
  • Sixteen steers were used to investigate the efficacy of the sustained-release implant of bovine somatotropin (bST) in improving growth and feed:gain ratio during 12 weeks. Administration of the 400 mg bST implant resulted in a 16.1% increase in growth rate, and this increase was significant (p<.05). The use of the sustained-release implant did not alter (p>.05) feed intake and feed:gain ratio. Thirty-four cows were used to investigate the efficacy of the sustained-release implant of bST in milk production during 4 weeks. Administration of the 200 mg bST implant resulted in an 8.7% increase in milk production, and this increase was significant (p<.05). Twenty-four barrows were used to investigate the efficacy of the sustained-release implant of porcine somatotropin (pST) in improving growth, feed:gain ratio and backfat thickness during 6 weeks. Administration of the 120 mg pST implant resulted in a 11.4% increase in feed:gain ratio and a 60% decrease in backfat thickness, and these results were significant (p<.05). But the use of the sustained-release implant did not alter (p>.05) growth rate and feed intake.

Power Spectal Analysis of Masticatory Muscles during Sustained Isometric Contraction and Recovery at Various Contraction Times (저작근의 등척성 수축시간 변화에 따른 Power Spectrum 분석에 관한 연구)

  • Wook Kim;Heung-Sang Lee;Young-Ku Kim
    • Journal of Oral Medicine and Pain
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    • v.20 no.2
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    • pp.269-281
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    • 1995
  • To study the characteristics of EMG power spectrum of masticatory muscles during sustained isometric contraction and recovery at various contraction times, the author analysed the EMG signals of anterior temporal and masseter muscles before, during, and after sustained isometric contraction at 50% level of maximum voluntary contraction (MVC) for 15,30,60 seconds. Twelve normal subjects were included in this study. The author came to following conclusions from the results. 1. MMF of anterior temporal muscle in the contraction period was significantly higher than that of masseter muscle during sustained isometric contraction regardless of isometric contraction times (p<0.05). 2. MMF in the contraction period decreased as the contraction time increased during sustained isometric contraction in both temporal and masseter muscles(p<0.05). 3. SMF in the contraction period increased as the contraction tie increased during sustained isometric contraction in both temporal and masseter muscles(p<0.01). 4. MMF in the first part of recovery period (20 seconds) decreased as the contraction time increased during sustained isometric contraction(p<0.05). However, MMF in the later parts of recovery period (20-120 seconds) showed no significant differences. 5. MMF of anterior temporl muscle in the recovery period was significantly higher than that of masseter muscle after sustained isometric contraction regardless of isometric contraction times (p<0.05). 6. The recovery rate of MF reached 100% in 100 seconds after the isometric contraction regardless of isometric contraction times.

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The Formulation and Dissolution Properties of Oral Sustained Release Sulindac Delivery System (설린닥의 경구용 지속성 제제설계 및 용출특성)

  • Rhee, Gye-Ju;Park, Sun-Hee;Suh, Sung-Su;Whang, Sung-Joo
    • YAKHAK HOEJI
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    • v.41 no.1
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    • pp.48-59
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    • 1997
  • Sustained release matrix tablets, pellets, and coated pellets for the delivery of sulindac were prepared using cellulose derivatives at various ratios, and evaluated for the dis solution pattern. The release of sulindac, from matrix tablets prepared with low viscosity HPMC was relatively fast, and especially the tablets made of Metolose SM released all of sulindac within 1 hr. The release of drug from tablets made of other HPMC derivatives were retarded in the order of the following: Pharmacoat 645>Pharmacoat 606>Pharrnacoat 606+HPC-L>HPC-L. The most sustained release pattern was observed with the preparation of high viscous polymer. Metolose 90 SH. While release of sulindac, from matrix type pellet containing 10mg/cap of Metolose 90 SH or 60 SH was completed within 1 hr, a prolonged release formulation (30% in 1 hr) was obtained by the inclusion of EC. Pellets coated with HPMC showed a fast release pattern (${\geq}$ 80% within 2 hrs), whereas pellets coated with HPMC and EC (molar ratio 1 : 1) showed a sustained release pattern (${\geq}$ 80% in 12 hrs), vath the release from EC pellets being the most sustained. Fast (naked) and slow release pellets coated with EC, Metolose 60SH 50cps and propylene glycol. and enteric pellets coated with HPMCP 55 and Myvacet$^{\circledR}$ were prepared, and combined at various ratios for the assessment of dissolution pattern. The result indicates the possibility that the development of 24 hr sustained release delivery systems containing sulindac for oral administration could be achieved by means of combining sustained and fast release pellets at a proper portion.

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Effect of Some Design Factors in the Front Panel on the Characteristics of a Plasma Display

  • Kim, Beong-Ju;Moon, Chelo-Hee
    • Journal of Information Display
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    • v.9 no.3
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    • pp.28-32
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    • 2008
  • Low sustained voltage $(V_s)$ and high luminous efficiency (lumen/Watts) are required for the enhanced performance of an AC PDP. Both are not realized in the same condition, however, because luminous efficiency decreases when the sustained voltage is lowered in most cases. In this study, the three design factors in the front panel of a PDP, i.e., the thickness and position of the bus electrode and the thickness of the dielectric layer, were chosen to investigate how they affect the sustained voltage and the luminous efficiency, and to find a way to optimize them. Two values were given to each of the three design factors, and experiments were done via full factorial design, i.e., with a total of eight conditions, using a 3-in.diagonal test panel. The changes in the sustained voltage and the luminous characteristics were explained in connection with the discharge characteristics of the PDP cells.

Release Characteristics of Terbutaline Sulfate Sustained-Release Beads In Vitro (서방성 Terbutaline sulfate bead의 방출특성)

  • Kim, Ki Man;Kim, Young Il;Hong, Soon Uk
    • Korean Journal of Clinical Pharmacy
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    • v.1 no.1
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    • pp.23-30
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    • 1991
  • The sustained-release beads containing terbutaline sulfate (TBS) were prepared by rotogranulation method. The drug was dusted on the non-pareil seeds in a CF-granulator. The sustained-release beads were obtained by coating the active beads with ethylcellulose or $Eudragits^{(R)}$, using in any case the same granulator employed for active beads preparation. The release characteristics of sustained-release beads were examined in vitro by rotating basket method applied to $Bricanyl^{(R)}$ durules which is a sustained-release TBS matrix tablet. The release of terbutaline from the beads in vitro was first-order, and the release rate was dependent on both the coat weight ratio and membrane hydrophilicity. Both surfaces of the beads before and after dissolution were smooth. The drug release pattern from the beads could be thought the diffusion through the polymer membrane. The release rate and the surface of the beads stored for 3 years at room temperature were the same with those of the initial beads.

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Application of chitosan resin formulae as a sustained-releasing form adjuvant (키토산 resin formulae의 서방효과(sustained-releasing effect) 보조제로서의 활용)

  • Kim, Sang-Uk;Kang, Mun-Il;Lee, Jae-Il;Kim, Tae-Jung
    • Korean Journal of Veterinary Service
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    • v.33 no.2
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    • pp.173-176
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    • 2010
  • Here, we report the suitability of using a resin-type chitosan formulae as a sustained-releasing form adjuvant in comparison with commercially well-known Freund's adjuvants. To induce the immunological responses, N-terminal region of Pasteurella multocida toxin was used as an antigen, which was found to be protective immunogen against P. multocida infection. Mice immunized with chitosan resin formulae showed statistically significant antibody induction (P<0.001) as much as that of Freund’s adjuvants. As a result, the resin-type sustained-releasing form chitosan formulae is thought to be a good candidate for a new type adjuvant.

GLR Charts for Simultaneously Monitoring a Sustained Shift and a Linear Drift in the Process Mean

  • Choi, Mi Lim;Lee, Jaeheon
    • Communications for Statistical Applications and Methods
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    • v.21 no.1
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    • pp.69-80
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    • 2014
  • This paper considers the problem of monitoring the mean of a normally distributed process variable when the objective is to effectively detect both a sustained shift and a linear drift. The design and application of a generalized likelihood ratio (GLR) chart for simultaneously monitoring a sustained shift and a linear drift are evaluated. The GLR chart has the advantage that when we design this chart, we do not need to specify the size of the parameter change. The performance of the GLR chart is compared with that of other control charts, such as the standard cumulative sum (CUSUM) charts and the cumulative score (CUSCORE) charts. And we compare the proposed GLR chart with the GLR charts designed for monitoring only a sustained shift and for monitoring only a linear drift. Finally, we also compare the proposed GLR chart with the chart combinations. We show that the proposed GLR chart has better overall performance for a wide range of shift sizes and drift rates relative to other control charts, when a special cause produces a sustained shift and/or a linear drift in the process mean.

A matrix-typed, sustained-releasing agent comprising agrochemical and the sustained-releasing product analysis for the preparation (매트릭스형의 서방성(Sustained-Releasing) 수분 인지방출 농약제제 및 그 제조를 위한 서방성 방출분석)

  • Park, Hae-Jun;Kim, Sung Ho;Kim, Hwa Jung
    • Analytical Science and Technology
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    • v.20 no.2
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    • pp.176-182
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    • 2007
  • The present study relates to a matrix-typed, sustained-releasing agent comprising agrochemical effective ingredients being capable of recognizing a content of moisture, and a preparation method thereof. The curdlan solution added to acid was formed matrix which has unique network structure. The matrix treated by heat lost water solubility. The network structure of matrix was opened in the aquatic condition but closed again in dry condition. Therefore, in the sustained-releasing formulation system, an agrochemical effective ingredient was released from the formulation only in the aquatic condition. Use of the composition according to the product can control a manifesting time of effects of agrochemicals and can provide agrochemicals with reduced harmful damages.