• Transactions of the Korean Society of Mechanical Engineers B
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• v.31 no.8
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• pp.702-710
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• 2007

Direct numerical simulation (DNS) is performed to investigate suppressed wake transition and occurrence of lock-on in the wake of a circular cylinder disturbed by sinusoidal perturbation at the Reynolds number of 220 (A-mode instability regime). The sinusoidal perturbation, of which the frequency is near twice the natural shedding frequency, is superimposed on the free stream velocity. It is shown that the wake transition behind the circular cylinder can be suppressed due to the perturbation of the free stream velocity. This change causes a jump in the Strouhal number from the value corresponding to A-mode instability regime to the value corresponding to retarded wake transition regime (extrapolated from laminar shedding regime) in the Strouhal-Reynolds number relationship. As a result, vortex shedding frequency is locked on the perturbation frequency depending not on the natural shedding frequency but on the modified shedding frequency.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.5
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• pp.291-297
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• 2010

The sleep homeostatic response significantly affects the state of anesthesia. In addition, sleep recovery may occur during anesthesia, either via a natural sleep-like process to occur or via a direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated for 2 hours with $ad$ $libitum$ sleep (Control), sleep deprivation (SD), and isoflurane anesthesia with delta-wave- predominant state (ISO-1) or burst suppression pattern-predominant state (ISO-2) with at least a 1-week interval. Electroencephalogram and electromyogram were recorded and sleep-wake architecture was evaluated for 4 hours after each treatment. In the post-treatment period, the duration of transition to slow-wave-sleep decreased but slow wave sleep (SWS) increased in the SD group, but no sleep stages were significantly changed in ISO-1 and ISO-2 groups compared to Control. Different levels of anesthesia did not significantly affect the post-anesthesia sleep responses, but the deep level of anesthesia significantly delayed the latency to sleep compared to Control. The present results indicate that a natural sleep-like process likely occurs during isoflurane anesthesia and that the post-anesthesia sleep response occurs irrespective to the level of anesthesia.