• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2271-2275
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• 2016

Background: The value of 5-aminolevulinic acid (ALA) in fluorescence detection of peritoneal metastases and the underlying mechanisms were evaluated in patients with peritoneal surface malignancies. Materials and Methods: Oral 5-ALA was administered at a concentration of 20 mg/kg body weight with 50 ml of water 2 hours prior to surgery (n=115). The diagnostic value of 5-ALA based fluorescence production was evaluated following white light inspection during prior to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Then, peptide transporter PEPT1 (ALA influx transporter) and ATP-binding cassette transporter ABCG2 (porphyrin efflux transporter) gene expression was determined with quantitative real time (qRT)-PCR and pathological diagnoses confirmed for all tissue samples. Results: The 5-ALA based photodynamic detection rate was 17% for appendiceal mucinous neoplasms, 54% for colorectal cancers, 33% for gastric cancers, 67% for diffuse malign peritoneal mesotheliomas, and 89% for epithelial ovarian cancer of peritoneal metastases. 5-ALA was detected in all cases of peritoneal metastases originating from cholangiocarcinomas whereas it was not able to detect any in granulosa cell and gastrointestinal stromal tumor cases. Furthermore, PEPT1 was overexpressed whereas ABCG2 expression was downregulated in tumors detected with fluorescence. Conclusions: 5-ALA provided 100% specificity and high sensitivity to detect peritoneal metastases in subgroups of patients with peritoneal surface mailgnancies. ALA influx transporter PEPT1 and porphyrin efflux transporter ABCG2 genes are important in tumor specific 5-ALA induced fluorescence in vivo. Further studies should clarify diagnostic utility of 5-ALA in peritoneal surface malignancies.

• 한국철도학회논문집
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• 제17권4호
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• pp.289-296
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• 2014

본 연구는 철도여행인솔자 288명을 대상으로 이들의 감정노동을 내면행동과 표면행동으로 구분하고, 감정노동이 고객지향성에 미치는 영향과 감정노동과 고객지향성 사이에서 조직지원인식의 조절효과를 실증분석 하였다. 분석결과를 요약하면, 우선, 철도 여행인솔자의 내면행동은 고객지향성에 유의한 정(+)의 영향을 미쳤으며, 표면행동은 유의한 부(-)의 영향을 미치는 것으로 나타났다. 둘째, 철도여행인솔자의 조직지원인식은 내면행동과 고객지향성과의 관계에서는 유의한 조절효과를 보이지 않았으나, 표면행동과 고객지향성과의 관계에서는 유의한 조절효과를 보이는 것으로 나타났다. 결론적으로 본 연구는 철도여행인솔자의 고객지향성을 높이기 위해서는 그들의 감정관리와 조직적 차원의 지원이 중요함을 시사하고 있다.

• 한국산업정보학회논문지
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• 제20권4호
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• pp.89-102
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• 2015

본 연구는 중국 백화점 판매원들이 판매과정에서 경험하게 되는 감정노동이 감정소모를 매개로 직무성과와 이직의도에 미치는 영향을 분석하는데 목적이 있다. 이를 위해 일상적 감정노동의 강도가 높은 백화점 판매사원 225명을 대상으로 설문조사를 수행하여 자료를 수집하였고, 구조방정식모형을 활용하여 수집된 자료를 분석하였다. 연구결과, 첫째, 표면행위는 감정소모에 긍정적인 영향을 미치는 것으로 나타났지만, 내면행위는 유의한 영향을 미치지 않는 것으로 나타났다. 둘째, 감정소모는 직무만족에 부정적인 영향을 미치는 반면, 이직의도에는 긍정적인 영향을 미치는 것으로 나타났다. 셋째, 지각된 조직지원은 내면행위가 감정소모에 미치는 정의 관계를 조절하는 것으로 나타났다. 이러한 검증결과를 기반으로 본 연구가 제시하는 이론적 시사점과 실무적 시사점을 논의하였다.

• 한국정보통신학회논문지
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• 제12권2호
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• pp.276-281
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• 2008

본 논문에서는 SVM(Support Vector Machine)을 이용하여 공칭 시스템의 동특성을 갖는 슬라이딩 평면 설계기법을 제안한다. 전형적인 슬라이딩 모드에서 슬라이딩 평면의 차수는 시스템의 차수보다 낮은 차수를 갖기 때문에 슬라이딩 평면은 $H_{\infty}$ 제어기의 동특성을 가질 수 없다. 그러므로 이 문제를 해결하기 위해서는 추가적인 상태들이 정의되어야 한다. 본 논문에서는 추가적인 상태를 정의하지 않고 SVM을 이용하여 공칭 시스템의 동특성을 가질 수 있는 슬라이딩 평면의 설계기법을 제안한다. 이 설계기법은 먼저 $H_{\infty}$ 제어기에 의해서 제어되는 공칭시스템의 상태들 간에 SVM을 이용하여 그 관계를 정립하며. 이를 바탕으로 새로운 슬라이딩 평면을 설계하며 이 평면은 $H_{\infty}$ 제어 시스템 특성을 가진다. 그 결과 파라미터 불확실성이 존재하더라도 제안된 제어기는 $H_{\infty}$ 제어기에 의해서 제어되는 공칭 시스템의 동특성을 가질 수 있다.

• 한국전문물리치료학회지
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• 제19권1호
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• pp.28-36
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• 2012

This study used an unstable platform to change the support surface type and position of both lower limbs in order to determine changes in weight distribution and muscle including the vastus medialis, tibialis anterior, lateral hamstring, and lateral gastrocnemius of both lower limbs were evaluated during knee joint flexing and extending in a semi-squat movement in 32 hemiplegic patients. The support surface conditions applied to the lower limbs were divided into four categories: condition 1 had a stable platform for both lower limbs; condition 2 had an unstable platform for the non-hemiplegic side and a stable platform for the hemiplegic side; condition 3 had a stable platform for the non-hemiplegic side and an unstable platform for the hemiplegic side; and condition 4 had an unstable platform for both sides. The normalized EMG activity levels of muscles and weight bearing ratio of both sides in the four surface conditions were compared using repeated measures ANOVA. A significant increase was found in the weight support distribution for the hemiplegic side in flexing and extending sessions in condition 2 compared to the other conditions (p<.05). A statistically significant decrease in significant decrease in asymmetrical weight bearing in flexing and extending sessions was observed for condition 2 compared to the other conditions (p<.05). A similar significant decrease was found in differences in muscular activity for both lower limbs in condition 2 (p<.05). The muscular activity of the hemiplegic side, based on the support surface for each muscle showed a significantly greater increase in condition 2 (p<.05). An unstable platform for the non-hemiplegic side and a stable platform for the hemiplegic side therefore increased symmetry in terms of the weight support distribution rate and muscle activity of lower limbs in hemiplegic patients. The problem of postural control due to asymmetry in hemiplegic patients should be further studied with the aim of developing continuous effects of functional training based on the type and position of the support surfaces and functional improvement.

• 대한기계학회논문집A
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• 제33권2호
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• pp.114-126
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• 2009

In this paper, a versatile multi-criteria optimization concept for fatigue life prediction is introduced. Multi-criteria decision making in engineering design refers to obtaining a preferred optimal solution in the context of conflicting design objectives. Compromise decision support problems are used to model engineering decisions involving multiple trade-offs. These methods typically rely on a summation of weighted attributes to accomplish trade-offs among competing objectives. This paper gives an interpretation of the decision parameters as governing both the relative importance of the attributes and the degree of compensation between them. The approach utilizes a response surface model, the compromise decision support problem, which is a multi-objective formulation based on goal programming. Examples illustrate the concepts and demonstrate their applicability.

• 한국세라믹학회지
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• 제29권6호
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• pp.496-504
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• 1992

Alumina tubes suitable for the support of gas separation membranes have been prepared by the slipcasting technique. These supports have the average pore size of 0.1 ${\mu}{\textrm}{m}$ within the narrow distribution. The sol-gel dipcoating process of nanoparticulate sols is very sensitive to microstructure of the support, and the coating on the inside surface of the tube is found to be more successful than on the outside surface. Nanoparticulate silica sols (0.82 mol/ι) have been synthesized by an interfacial hydrolysis reaction between TEOS and high alkaline water. When coating an alumina tube with these sols, the minimum limits of the particle size and the aging time required for forming the coated gel layer at the given pH are provided. It is optimum to coat the support with less concentrated sols stabilized through aging for the appropriate time (more than 22 days) at the lower pH (pH 2.0) for producing a reproducible crack free thin film coating in composite membranes.

• 한국중재학회지:중재연구
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• 제28권2호
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• pp.179-200
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• 2018

The purpose of this study is to investigate the effects of service training and arbitration support on superstore workers' work performance. The conclusion could be summarized as follows. First, as a result of Hypothesis 1 that service training and arbitration support for superstore workers would significantly affect the factor of workers' emotional labor, when surface acting of emotion and frequency of expressing emotions were the dependent variable, only arbitration support was positively correlated. When emotional diversity was the dependent variable, there was a significantly positive relationship with service training. Second, for Hypothesis 2 that service training and arbitration support for superstore workers would significantly influence the workers' job satisfaction, it was found that only organizational support was significantly positive when wage satisfaction was the dependent variable. When job satisfaction was the dependent variable, service training and arbitration support were significantly correlated positively. Third, for Hypothesis 3 that service training and arbitration support for superstore workers would significantly affect the service delivery level when service responsiveness was the dependent variable, service training and arbitration support were significantly positive. When service expertise was the dependent variable, there was also a significantly positive relationship with service training and arbitration. On the other hand, all the three independent variables-service training, organizational support, and arbitration support-showed a significantly positive relationship when the willingness and effort of service was the dependent variable.

• The Journal of Korean Physical Therapy
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• 제26권2호
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• pp.97-103
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• 2014

Purpose: The aim of this study was to clarify the gender difference during standing balance in accordance with recruitment of abdominal muscles against sudden support surface translation. Methods: Twenty healthy males (n = 10, $26.50{\pm}3.54$ years, $170.60{\pm}6.30cm$, $72.80{\pm}5.69kg$) and females (n = 10, $24.40{\pm}2.63$ years, $163.00{\pm}4.97cm$, $52.10{\pm}4.41kg$) participated in the study. Each subject performed standing balance task on a platform, which moved in the anterior and posterior direction, with a total of 18 trials in three abdominal conditions (resting, hollowing, and bracing). We analyzed angular displacement of thoracic and lumbar spine and linear displacement of center of mass for evaluatione of spinal stability and standing balance, respectively. Results: Angular displacement of thoracic and lumbar spine and linear displacement of center of mass did not differ significantly between female and male in all conditions. Conclusion: Our results indicate that the ability to maintain spinal stability and standing balance were similar between male and female regardless of the abdominal contractile conditions and the direction of support surface translation.

• 대한의용생체공학회:의공학회지
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• 제30권6호
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• pp.495-502
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• 2009

This paper investigated the effects of dynamic postural control for maintaining upright standing on a support surface during continuous sinusoidal horizontal translation in anterior-posterior direction. 15 healthy young subjects participated in this experiment. The analysis of body movement was analyzed using Ariel Performance Analysis System. Motion pattern was analyzed by seven markers on subject's body. Position of markers were head, chest, hip, right knee, left knee, right ankle and left ankle. Seven different frequencies of support surface were employed ; 0.1, 0.25, 0.5, 0.75, 1, 1.5 and 2Hz at 2cm of moving path of motionbase. The experiments were performed dynamic postural reponses at the condition of eye open. The results showed that median frequency of the knee, ankle were increased in all frequency bands. Following the frequency of perturbation increased, postural control strategy was changed from ankle strategy to combined strategy. The experiment results could be applied to the dynamic postural training for the elderly and the rehabilitation training for the patients to improving the ability of postural control.