• 제목/요약/키워드: Suchong virus

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흰넓적다리붉은쥐 유래 한타바이러스 분리 및 분자생물학적 특성 비교 (Isolation of Apodemus peninsulae-borne Hantavirus and Comparison of Molecular Biological Characteristics)

  • 송기준;윤형선;고은영;정기모;박광숙;이용주;송진원;백락주
    • 대한바이러스학회지
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    • 제30권1호
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    • pp.19-28
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    • 2000
  • Two distinct hantaviruses have been isolated from Apodemus agrarius in 1976 and Rattus norvegicus in 1980 in Korea. Since our serosurveys conducted in 1994, a genetically distinct hantavirus from Apodemus peninsulae has been investigated. To isolate hantavirus from Apen insulae captured in Korea, the lung homogenate of seropositive Apeninsulae inoculated Vero E6 cells. Viral antigen was detected in a progressively higher percentage of cells with subsequent passage after 80 days postinoculation. The new isolate from seropositive Apodemus peninsulae was designated Suchong virus after Suchong valley located in northeastern region of South Korea. Comparing with hantaan virus 76-118 strain, Suchong virus-1, 2, 3 and 4 showed the similarity of $71.0{\sim}91.8%$ at nucleotide and $90.9{\sim}94.8%$ at amino acid sequences in 231 nucleotides region of M segment, and the similarity of $75.1{\sim}81.0%$ at nucleotide and $97.5{\sim}100%$ at amino acid sequences in 237 nucleotides of S segment.

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