• Analytical Science and Technology
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• v.18 no.4
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• pp.362-367
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• 2005

The human mitochondrial genome (mtDNA) has been an important tool in the field of forensic investigations. Within the entire mtDNA molecule, the non-coding control region which is approximately 1,100 bp including hypervariable region I and II (HV1 and HV2) is widely studied because it is highly polymorphic and useful for human identification purposes. In this study, 360 unrelated Koreans were analyzed in HV1. The number of polymorphic sites and genetic lineage were 124 and 210, respectively. The most prevalent substitution was C-T and 75.8% of DNA showed C-T substitution at 16223. There were 20 kinds of polymorphism between 16180 and 16193 including insertion and deletion. The most frequent haplotype was [16223T, 16362C] representing 5%. Approximately 25.9% of DNA showed the same haplotype in at least two samples. The gene diversity was calculated to 0.996 and the probability of two unrelated perosons having the same haplotype was determined to 0.7%.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.28 no.3
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• pp.533-543
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• 2018

In this paper, we propose an MILP-based method for Optimal Probability of Bit-based Differential Characteristic in SP(Substitution-permutation) ciphers based on Automatic Differential Characteristic Searching Method of Sasaki, et al. In [13], they used input/output variables and probability variables seperatably, but we simplify searching procedure by putting them(variables) together into linear inequalities. Also, In order to decrease the more linear inequalities, we choose Espresso algorithm among that used by Sasaki, et al(Quine-McCluskey algorithm & Espresso algorithm). Moreover, we apply our method to GIFT-64, GIFT-128, SKINNY-64, and we obtained results in the GIFT(Active S-boxs : 6, Probabilities : $2^{-11.415}$) compared with the existing one.(Active S-boxs : 5, Probabilities : unknown). In case of SKINNY-64, we can't find better result, but can find same result compared with the existing one.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.12C
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• pp.280-291
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• 2001

LL (Leased Line service) is a facility-based service as a traditional business data service, but new competition services, such as FR (Frame Relay), VPN (Virtual Private Network), and ATM (Asynchronous Transfer Mode), are value-added services. Because of different service classifications, it is hard to gather necessary data for the service providers to plan their market strategies and regulations and policies are also applied asymmetrically to each service provider. Therefore an appropriate market classification is required for the business data services. After various methods of market classification are reviewed, the Hendry model is selected in this paper to analyze substitution-degree among brands or among services. Since the structure of virtual competitions is required for the Hendry model to be applied to data service market, the market is analyzed first by the well-known Porter's model. By the analysis of Porter's model, two virtual competition structures are set up - one is for the competitions among leased line service providers, and the other is for the competitions among business data services such as LL, FR, VPN and ATM. After the Hendry model is applied to each competition structure, it is confirmed that 7 LL service providers do not compete directly, but 2 sub-markets exist for the LL service provisions. However, it is shown that 4 business data services compete directly. Using the Switching Probability Matrix from Hendry model, future market shares of LL service providers and market shares of business data services are forecasted. These empirical results are helpful for service providers to set competitive strategies with the minimization of cannibalization effect and they can easily and efficiently predict their market demands.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.34 no.5
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• pp.293-300
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• 2021

In this study, the microstructure and thermal conductivity correlation was investigated for concrete materials used in concrete thermal energy storage (CTES) among real-time energy storage devices. Graphite was used as admixture to increase the thermal conductivity performance of the CTES. Concrete specimens of 10% and 15% substitution of cement by mass with graphite, as well as ordinary portland cement (OPC) specimens were prepared, and the microstructural changes and effects on thermal conductivity were analyzed. Porosities of OPC and concrete with graphite were compared using micro-CT, and the microstructural characteristics were quantified using probability functions. Three-dimensional virtual specimens were constructed for thermal analysis, to confirm the effect of microstructural characteristics on thermal conductivity, and the results were compared with the measured conductivity obtained using the hot-disc method. To identify thermal conductivity of graphite for thermal analysis, solid phase conductivity was inversely determined based on simulation and experimental results, and the effect of graphite on thermal conductivity was analyzed.

• Pediatric Infection and Vaccine
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• v.7 no.1
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• pp.83-93
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• 2000

Purpose : Urabe AM-9 strain was known to be associated with increased aseptic meningitis. The reason for high incidence of vaccine-associated meningitis was known that nucleotide(nt) substituted form G to A at position 1081 of the hemagglutinin-neuraminidase(HN) gene and therefore, glutamic acid changed to lysine at amino acid 335. We assessed by comparing nt sequence of the HN gene form Urabe AM-9 strain with wild strain and documented the correlation between nt substitution and vaccine-associated meningitis. Methods : Two lots of Urabe AM-9 vaccine distributed in Korea and mumps wild strains isolated from 1998 through 1999 were analysed. Analysis was made by nt sequencing following amplification of HN gene by RT-PCR. Results : Nucleotide substitution at position 343, 1476, 1570 was not found in both Urabe AM-9 vaccines and wild strains. But analysis of vaccine strains and wild strains isolated from patients revealed substitution from G to A at nt 1081 of the HN gene. Therefore, it encodes lysine instead of glutamic acid at amino acid 335. There was no mixture from of G and A at nt 1081. Nt at 1470 of one lot of Urabe AM-9 vaccines changed from C to A after Vero cell passage. Nt at 1727 of vaccines and wild strains was substituted A to G, so it encodes glycine instead of aspartic acid. Conclusion : Nucleotide analysis of HN gene revealed that nt 1081 of Urabe AM-9 vaccines and wild strains had wild type AAA($Lys^{335}$) instead of variant type GAA($Glu^{335}$). The results of this study suggest that there was a probability of vaccine-associated meningitis due to Urabe AM-9 in Korea before. But incidence of actual side effect was not evaluated because there was no reporting system in Korea.

• Korean Journal of Poultry Science
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• v.11 no.2
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• pp.109-114
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• 1984

The experiment was made to study the effect of levels of metabolizable energy of basal diets on apparent metabolizable energy (AME) and true metabolizable energy (TME) values of corn and soybean meals. The test materials, corn and soybean meals, were substituted with basal diet at 50% and 30%, respectively. The excreta of fed md unfed birds were collected for 30 hours. The results obtained were as follows; 1. The AME values of corn were not significantly different among treatments (P＞0.05) except for 2400 Kcal/13% treatment, The AME values of soybean meals differed significantly between 2,400 Kcal/13% and 2,800 Kcal/15% or 3,000 Kcal/16%, but were not different between 2,400 Kcal/13% and 2,600 Kcal/14 % (probability at 5% level). 2. The energy levels of basal diets did not affect the AME values of corn and soybean meals (P＞0.05) except 2,400 Kcal/13% treatment. This fact indicates that it is not necessary to change energy levels of basal diet according to test materials. 3. That the values of standard error of soybean meals were higher than those of corn was resulted from its low level of substitution with basal diet. 4. The TME values of corn showed significant differences (P＜0.05) between 2,400Kcal/13% treatment and other treatments but those of soybean meals were not different among all treatments (P＞0.05). 5. The reason that the AME values of corn and soybean meals and the TME values of corn reduced significantly in 2,400 Kcal/13% could be explained by the effect of interaction among ingredients in the diet.

• Journal of Korean Society of Forest Science
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• v.88 no.1
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• pp.117-123
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• 1999

Consumer surplus is to be a value concerning a time horizon. Especially it is very important how long time horizon would be chosen in contingent market. This study aimed to provide causes of difference recreation benefits through discount rate in many aspects. The data were collected by personal interviews with visitors in Songnisan National Park. The respondents answered yes or no, dichotomous choice, on recreation benefits according to a chosen time horizon, one year or five years. The probit model was used in the analysis. In order to avoid the truncation bias of upper bound, the median was chosen as the recreation benefits of visitor. As the result, the value was evaluated to be 16,569 Won for one year and 27,111 Won for five years. The discount rate is estimated 153% annually to coincide different recreation benefits. The reasons of the high discount rate were to be interpreted as following five types : (1)uncertainty of future consumption (2)increasing of probability of the substitution owing to increasing of time horizon (3)recognization of different time horizons (4) effect by the price ratio of goods and utility function (5) overestimation of the recreation benefits owing to a basic premium of payment vehicle.

• The Korean Journal of Financial Management
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• v.21 no.2
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• pp.99-123
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• 2004

We focus in this study on incremental financing decisions and estimate a logit model for the probability a firm will choose a private placement over a public bond issue. We hypothesize that information asymmetry, financial risk, agent cost, and proprietary information may affect a firm's choice between public debt and private placements. We find that as the size of firm increases, the probability of choosing a private placement declines significantly. The age of the firm, however, is not a significant factor affecting the firm's choice between public and privately-placed bond. The coefficients on the firm's leverage and non-investment grade dummy are significantly positive, meaning firms with high financial risk and credit risk select private placements. The findings regarding agency-related variables, PER and Tobin's Q, are somewhat complex. We find significant evidence that firms with high PER prefer private placements to public bonds, suggesting that borrowers with options to engage in asset substitution or underinvestment are more likely to choose private placements. The coefficient of Tobin's Q is negative, but not significant, which weakly support the hold-up hypothesis. When we construct an interaction term on the Tobin's Q with a non-investment rating dummy, however, the Tobin's Q interaction term becomes positive and significant. Thus, high Tobin's Q firms with a speculative rating are significantly more likely to choose a private placement, regardless of the potential hold-up problems. The ratio of R&D to sales, proxy for proprietary information, is positively significant. This result can be interpreted as evidence in favor of a role for proprietary information in the debt sourcing decision process for these firms.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.3
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• pp.47-56
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• 2020

In this study, three levels of W/B(Water to Binder) ratio (0.37, 0.42, 0.47) and substitution ratio of GGBFS (Ground Granulated Blast Furnace Slag) rate (0 %, 30 %, 50 %) were considered to perform RCPT (Rapid Chloride Diffusion Test) at the 1,095 aged day. Accelerated chloride diffusion coefficient and passed charge of each concrete mixture were assessed according to Tang's method and ASTM C 1202, and improving behaviors of durability performance with increasing aged days are analyzed based on the test results of previous aged days from the preceding study. As the age of concrete increases, the passed charge and diffusion coefficient have been significantly reduced, and especially the concrete specimens containing GGBFS showed a significantly more reduction than OPC(Ordinary Portland Cement) concrete specimen by latent hydraulic activity. In the case of OPC concrete's results of passed charge, at the 1,095 days, two of them were still in the "Moderate" class. So, if only OPC is used as the binder of concrete, the resistance performance for chloride attack is weak. In this study, the time-parameters (m) were derived based on the results of the accelerated chloride diffusion coefficient, and the deterministic and probabilistic analysis for service life were performed by assuming the design variable as a probability function. For probabilistic service life analysis, durability failure probabilities were calculated using Monte Carlo Simulation (MCS) to evaluate service life. The service life of probabilistic method were lower than that of deterministic method, since the target value of PDF (Probability of Durability Failure) was set very low at 10 %. If the target value of PDF suitable for the purpose of using structure can be set and proper variability can be considered for each design variable, it is believed that more economical durability design can be made.