• Title/Summary/Keyword: Substance Abuse

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The Effect of Health Promotion Behavior on Emotional Happiness

  • Lee, Byunghyun;Kim, Jungae
    • International Journal of Advanced Culture Technology
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    • v.7 no.1
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    • pp.20-27
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    • 2019
  • This study was designed to examine the affect health promotion behavior to emotional happiness for 20-30's in Korea through cross-sectional descriptive research. There were a total of 279 people who participated in this study, 198(71.0%) were males and 81(29.0%) were females. The data collection period was from December 1 to 15, 2018. The tools used to measure health promotion behaviors were HPB (Health Promotion Behavior) developed by Walker et al., and emotional happiness was PANAS (Positive and Negative Affect Scale) by Developed by Watson et al., All data was analyzed using SPSS 18.0 program. As a result of analysis, 62 (49.6%) were solving interpersonal problems and stress relief while drinking, and the people who ate twice a day were most frequent. In conclusion, health promotion behaviors have a strong correlation with emotional happiness. Based on the above results, it was suggested that the program of happiness for lining in the 20-30s age groups should strengthen the contents of health responsibility, guidance of substance abuse, formation of social relations and self actualization.

The Factors Related to Substance Use among Korean Adolescents: Focusing on Sexual Experiences and Risky Sexual Behaviors (한국 청소년의 약물사용 관련요인: 성경험과 위험 성행동을 중심으로)

  • Park, Min Hee;Jeon, Hae Ok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.5
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    • pp.3333-3343
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    • 2015
  • The purpose of this study is to investigate factors related to substance use focusing on the sexual experiences and risky sexual behaviors among Korean adolescents. This study conducted with a secondary data analysis using the Seventh Korea Youth Risk Behavior Web-based Survey 2011 in South Korea. The study participants selected 75,643 Korean adolescents who were recruited anonymously through national web-based survey. Data were analyzed using descriptive statistics, rao-Scott ${\chi}^2$, and logistic regressions considering complex samples. Results indicated that substance use was significantly associated with sexual experiences such as sexual intercourse with the opposite sex (adjusted OR=5.691; 95% CI=4.223-7.670), sexual intercourse with the same sex (adjusted OR=21.180; 95% CI=14.704-30.507) and risky sexual behaviors such as sexual assaults (adjusted OR=9.936; 95% CI=7.217-13.680), date rape (adjusted OR=16.979; 95% CI=11.648-24.751), sexual intercourse after drinking (adjusted OR=6.564; 95% CI=3.986-10.810), unexpected pregnancies (adjusted OR=18.628; 95% CI=8.476-40.936), and sexually transmitted diseases (adjusted OR=21.872; 95% CI=13.920-34.367) in Korean adolescents. Findings of this study show that adolescents who use substances are more likely to engage in risky sexual behaviors. Therefore, intervention program should be designed to consider both substance use and sexual problems and to include the effective approaches at the family and school level.

ADOLESCENT VIOLENCE TOWARD PARENTS (청소년의 부모폭행에 대한 연구)

  • Chun, Ryo-Sook;Min, Sung-Kil;Oh, Kang-Sup;Lee, Si-Hyung;Lee, Ho-Bun
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.8 no.2
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    • pp.199-206
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    • 1997
  • Object:The purpose of this study was to investigate frequency and risk factor of violence toward parents seen in adolescents. We also want to apply this data toward developing a prevention program for adolescent violence. Method:A total of 1,345 students from 5 middle schools in Seoul, participated in this study:675 males, 670 females. We administered self-reporting questionnaire including violence toward parents, exposure to violence, family history of alcoholism, substance abuse of adolescetnt and dermographic data etc. Result:The frequency of boys’ violence toward parent was 2.8%, which was significantly higher than girls’(p<0.001). The frequency of violence toward the father was higher than the mother. The risk factors for violence toward parents were sex, parental alcohol problem, adolescent alcohol-smoking-drug problem, exposure to violence at home in the last year and exposure to violence in the life(p<0.0001). The grade, punishment, socioeconomic status, educational level of parent were not significantly related to violence toward parents. Conclusion:These suggest that adolescent violence toward parents is not rare problem any more and preventive intervention is needed for high-risk groups, that is related with experience domestic violence, substance abuse, alcoholic parent.

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Differentially Expressed Genes in Period 2-Overexpressing Mice Striatum May Underlie Their Lower Sensitivity to Methamphetamine Addiction-Like Behavior

  • Sayson, Leandro Val;Kim, Mikyung;Jeon, Se Jin;Custodio, Raly James Perez;Lee, Hyun Jun;Ortiz, Darlene Mae;Cheong, Jae Hoon;Kim, Hee Jin
    • Biomolecules & Therapeutics
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    • v.30 no.3
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    • pp.238-245
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    • 2022
  • Previous reports have demonstrated that genetic mechanisms greatly mediate responses to drugs of abuse, including methamphetamine (METH). The circadian gene Period 2 (Per2) has been previously associated with differential responses towards METH in mice. While the behavioral consequences of eliminating Per2 have been illustrated previously, Per2 overexpression has not yet been comprehensively described; although, Per2-overexpressing (Per2 OE) mice previously showed reduced sensitivity towards METH-induced addiction-like behaviors. To further elucidate this distinct behavior of Per2 OE mice to METH, we identified possible candidate biomarkers by determining striatal differentially expressed genes (DEGs) in both drug-naïve and METH-treated Per2 OE mice relative to wild-type (WT), through RNA sequencing. Of the several DEGs in drug naïve Per2 OE mice, we identified six genes that were altered after repeated METH treatment in WT mice, but not in Per2 OE mice. These results, validated by quantitative real-time polymerase chain reaction, could suggest that the identified DEGs might underlie the previously reported weaker METH-induced responses of Per2 OE mice compared to WT. Gene network analysis also revealed that Asic3, Hba-a1, and Rnf17 are possibly associated with Per2 through physical interactions and predicted correlations, and might potentially participate in addiction. Inhibiting the functional protein of Asic3 prior to METH administration resulted in the partial reduction of METH-induced conditioned place preference in WT mice, supporting a possible involvement of Asic3 in METH-induced reward. Although encouraging further investigations, our findings suggest that these DEGs, including Asic3, may play significant roles in the lower sensitivity of Per2 OE mice to METH.

The Survey of Adolescent Drug abuse in Seoul (청소년 약물남용 실태에 관한 연구 -서울지역을중심으로-)

  • 김소야자;현명선;성경미;공성숙
    • Journal of Korean Academy of Nursing
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    • v.23 no.3
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    • pp.487-503
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    • 1993
  • This study was designed to investigate the situation of adolescent drug use in Seoul, and to com-pare this with the 1991 survey in order to better understand the present situation. The subject for this study were 1000 students in High School and Middle School. The data were collected during the period from september 1, 1992 to December 30, 1992. The guestionnaire developed by Kim So Ya Ja (1991) to survey adolescent drug use was used. The data was analyzed using descriptive statistics, 1-test and ANOVA with the SPSS program. The results of this study can be summarized as follows 1. Prevalence of Substance use : Antihistamines were used by 0.3% of adolescent, Sedatives 0.6%, Stimulants 8.1%, Hallucinogens 0.9%, Inhalants 3.2%, Narcotics 1.7%, and Analgetics 154.3%. 2. Trend in substance use compared to the 1991 surbey : Alcohol use increased from 52.8% to 63.7% and narcotics from 0.6% to 1.7%, while Smeking, Analgetics, Antihistamines, Sedatives, and Inhalants showed a decrease. 3. Smoking and Alcohol use : Twenty five percent of school adolescent had experienced cigarette smoking and 63.7% of school adolescent had experienced alcohol use. 4. Motives for drug use : The highest was avoidence of sleep at 49.4% and the next highest was adventure seeking at 27.7%. As to feeling after drug use, 34.3% felt apathy, 22.8% had feelings of sleepiness and unconsciousness. 5. Places were dreg were purchased : The most frequent was the drug store (78.3%) and 84.4% of the respondents answered that drug purchase was easy and 86.7% that drug use was mainly at home. 6. Related Variables : There was a statistically significent high score for drug and alcohol use by adolescents whose fathers used drugs. (PC.05) In conclusion, adolescents in Seoul showed in decrease in the tendency to use drugs compared to the 1991 survey, however drugs which are habit-forming and lead to dependency are still being abused. Therefore, counter-plans and preventive stratiges are important.

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Forensic analysis of toxic substances in fatalities with suspected companion animal cruelty (반려동물 학대 의심 폐사축에 대한 중독물질검사 연구)

  • JeongWoo Kang;Ah-Young Kim;Hyun Young Chae;Hanae Lim;Suncheun Kim;Bok-Kyung Ku;Kyunghyun Lee
    • Korean Journal of Veterinary Research
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    • v.63 no.3
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    • pp.21.1-21.6
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    • 2023
  • The increasing prevalence of toxic substance-exposure in pets in South Korea endangers the health and safety of numerous companion animals, and has become a cause for concern. Notably, the annual incidence of forensic analysis in pets has increased by more than 150% in South Korea, mainly in populous regions such as Seoul, Incheon, and Gyeonggi. In response to this growing issue, veterinary forensic examinations were conducted on 549 dogs and cats from 2019 to 2022. This study revealed the presence of various toxic substances, including pesticides, insecticides, and drugs such as analgesics, anesthetics, antidepressants, and muscle relaxants, in pets. Among the 38 different toxins identified in pets, coumatetralyl, methomyl, terbufos, and buprofezin were the most frequently detected. In this study, toxic substances for pets were identified based on the "toxic agent list for humans," developed by the National Forensic Services, because no list of toxic agents for animals currently exists and data regarding potentially toxic substances for dogs and cats is limited. This is one of the limitations of this study, and necessitates the establishment of a toxic agent list for animals. Continued monitoring and research is also recommended to reveal the incidence, causes, and solutions of toxicity in animals.

Health Education Program Development for Infants, Toddlers and Preschool Children (영유아보건생활 교육프로그램 개발에 관한 연구)

  • Lee Ja-Hyung;Kim Il-Ok
    • Journal of Korean Academy of Nursing
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    • v.35 no.2
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    • pp.262-269
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    • 2005
  • Purpose: The purpose of this study was to develop a health education program for child care workers of infants, toddlers and preschoolers to improve their care ability. The program provided child care teachers and children with information on how to take care of their health. Method: This program development was based on a systematic design of instruction by Dick & Carey(1996). The process included a review of literature, setting an instructional goal, getting advice from various experts, designing instruction and instructional medias, designing formative evaluation, revising the program and making a summative evaluations. Result: The products of this program were the 'Teachers Guide Book & CD-ROM.' The guide book included health education programs for infants, toddlers and preschoolers. The infant program included a basic baby care program for teachers. The toddlers and preschoolers program included basic health promotion, dental health, nutrition management, communicable disease prevention, substance abuse prevention and a safety program. Conclusion: These programs provided a systematic content of health education for children and their teachers, and useful data which can be applied to child care centers.

In vitro Metabolism of Methallylescaline in Human Hepatocytes Using Liquid Chromatography-High Resolution Mass Spectrometry

  • Kim, Sunjoo;Kim, Ju-Hyun;Kim, Dong Kyun;Lee, Jaesin;In, Sangwhan;Lee, Hye Suk
    • Mass Spectrometry Letters
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    • v.9 no.3
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    • pp.86-90
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    • 2018
  • Methallylescaline, 2-(3,5-dimethoxy-4-[(2-methylprop-2-en-1-yl)oxy]phenyl)ethanamine, is a new psychoactive substance with potent agonist of 5-HT receptor, but there is little information on its pharmacological effect, metabolism, and toxicity. It is necessary to characterize the metabolic profiling of methallylescaline in human hepatocytes using liquid chromatography-high resolution mass spectrometry. Methallylescaline was metabolized to three hydroxy-methallylescaline (M1-M3) and dihydroxy-methallylescaline (M4) via hydroxylation in human hepatocytes. CYP2D6, CYP2J2, CYP1A2, and CYP3A4 enzymes were responsible for the metabolism of methallylescaline. The metabolites as well as methallylescaline would be used for monitoring the abuse of methallylescaline.

Tobacco Use, Beliefs and Risk Awareness in University Students from 24 Low, Middle and Emerging Economy Countries

  • Peltzer, Karl;Pengpid, Supa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.10033-10038
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    • 2014
  • The aim of this study was to determine the prevalence of tobacco use, beliefs and risk awareness and psychosocial correlates of tobacco use among university students in 24 low, middle and emerging economy countries. Using anonymous questionnaires, data were collected from 16953 undergraduate university students (mean age 20.9, SD=2.9) from 25 universities in 24 countries across Asia, Africa and the Americas. Results indicate that overall 13.3% of the university students were current tobacco users, 22.4% for men and 6.6% for women, ranging from 3.8% in Singapore to 32.5% in Cameroon. The risk awareness of the smoking lung cancer link was 83.6%, while the risk awareness of the smoking heart disease link was 46.5%. Multivariate logistic regression found that older age, male gender, having a wealthy family background, living in a low income country, residing off campus on their own, poor beliefs in the importance not to smoke, awareness of the smoking heart disease link, hit by a sexual partner, depressive symptoms, and substance use (binge drinking and illicit drug use) were associated with current tobacco use.

Infrequent Hemorrhagic Complications Following Surgical Drainage of Chronic Subdural Hematomas

  • Rusconi, Angelo;Sangiorgi, Simone;Bifone, Lidia;Balbi, Sergio
    • Journal of Korean Neurosurgical Society
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    • v.57 no.5
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    • pp.379-385
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    • 2015
  • Chronic subdural hematomas mainly occur amongst elderly people and usually develop after minor head injuries. In younger patients, subdural collections may be related to hypertension, coagulopathies, vascular abnormalities, and substance abuse. Different techniques can be used for the surgical treatment of symptomatic chronic subdural hematomas : single or double burr-hole evacuation, with or without subdural drainage, twist-drill craniostomies and classical craniotomies. Failure of the brain to re-expand, pneumocephalus, incomplete evacuation, and recurrence of the fluid collection are common complications following these procedures. Acute subdural hematomas may also occur. Rarely reported hemorrhagic complications include subarachnoid, intracerebral, intraventricular, and remote cerebellar hemorrhages. The causes of such uncommon complications are difficult to explain and remain poorly understood. Overdrainage and intracranial hypotension, rapid brain decompression and shift of the intracranial contents, cerebrospinal fluid loss, vascular dysregulation and impairment of venous outflow are the main mechanisms discussed in the literature. In this article we report three cases of different post-operative intracranial bleeding and review the related literature.