• Journal of Digestive Cancer Research
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• 제5권1호
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• pp.44-49
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• 2017

Background: 최근 제안된 조기위암에 대한 미세침습 치료법은 내시경점막하박리술(endoscopic submucosal dissection, ESD)혹은 종양 부위를 전층 절제(endoscopic full-thickness gastric resection, EFTGR)을 통해 위 절제를 최소화하고 동시에 복강경을 통해 감시림프절 절제(sentinel lymph node dissection, SLND)를 시행함으로써 그 가능성을 제시했었고, 이들을 각각 ESN (endoscopic submucosal dissection with laparoscopic sentinel lymph node dissection), Hybrid-NOTES (endoscopic full-thickness gastric resection with laparoscopic sentinel lymph node dissection)라고 명명하였다. 본 고에서는 림프절 전이 위험성이 높은 조기위암에 대해 이 두 치료법을 시행받은 환자들의 장기 추적 결과를 평가하고자 한다. Methods: 이 후향적 연구는 2009년 1월부터 2013년 5월 중에 ESN 혹은 Hybrid-NOTES를 시행받은 환자들이 포함되었다. Results: 총 42명의 환자들이 연구에 포함되었고, ESN 21명, Hybrid-NOTES 21명이 각각 등록되었다. ESN을 시행받은 21명 중 4명, Hybrid-NOTES를 시행받은 5명은 이 미세침습수술 후 추가 수술을 받아야 했다. 아직까지 이 수술 후 사망 환자는 없지만 ESN을 시행받은 1명의 환자에서 림프절 전이가 발견되어 항암치료를 받고 있다. Conclusion: 조기위암의 미세침습 수술인 ESN 혹은 Hybrid-NOTES는 좋은 장기 추적 결과를 보여주었다. 이 방법들은 향후 림프절 전이 위험성이 높은 조기위암에서 ESD와 gastrectomy 사이에 속한 환자들에게 좋은 치료법이 될 수 있을 거라고 생각된다.

• 대한소화기학회지
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• 제72권6호
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• pp.322-324
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• 2018

• Clinical Endoscopy
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• 제56권6호
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• pp.738-740
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• 2023

• 대한구순구개열학회지
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• 제15권1호
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• pp.39-50
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• 2012

A submucous cleft palate(SMCP) is characterized by a midline deficiency or lack with/without incorrect positioning of muscular tissues in the soft palate, and by a bony defect in the midline or the center of the hard palate. Velopharyngeal incompetence(VPI) related to this SMCP has been managed by various surgical and prosthetic techniques. Because the individual diagnosis and treatment of SMCP patients was not easy to the speech pathologist and to the maxillofacial reconstructive surgeons, and for the better understanding and for the ideal approaches to the SMCP patients, we reviewed several recent articles about grading system in the SMCP caused by VPI, and summarized in this review article.

• Journal of Chest Surgery
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• 제38권8호
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• pp.589-593
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• 2005

식도에 발생하는 신경초종은 매우 드문 질환으로 알려져 있으며, 술 전 대부분 식도 점막하종양으로 진단된다 확진은 술 후 시행되는 면역조직화학 검사에 의해 내려진다. 본원에서는 3개월 동안의 연하곤란을 주소로 내원한 63세 여자 환자와, 2개월간의 간헐적인 연하곤란을 주소로 내원한 39세의 여성에서 발생한 식도 점막하 종양을 우측개흉술을 통한 식도 절제술 및 종양 적출술을 각각 시행하여 제거하였다. 술 후 면역조직화학 검사 결과 2예 모두 S-100양성으로 나타나 식도의 양성 신경초종으로 확진되었다.

• Journal of Yeungnam Medical Science
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• 제33권1호
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• pp.21-24
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• 2016

Esophageal schwannoma is a very rare submucosal tumor. We report successful management of esophageal schwannoma in a 41-year-old man who complained of progressively worsening dysphagia. A huge submucosal tumor was found via endoscopy and a chest computed tomography scan. Esophagectomy was performed with no post-operative complications. Post-operative immunohistochemistry staining showed a positive result for S-100 and negative results for c-kit and CD34. The post-operative mild dysphagia persisted, and the follow-up endoscopic findings revealed anastomosis site stenosis. Approximately 2 months later, we performed endoscopic balloon dilatation. We report herein a case of esophageal schwannoma with reviews.

• Journal of Yeungnam Medical Science
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• 제30권2호
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• pp.132-135
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• 2013

Gastric lipoma is a typical benign submucosal tumor that is usually asymptomatic and is generally detected incidentally when performing gastroscopy. However, depending on its size and location, an atypical gastrointestinal lipoma can cause abdominal pain, diarrhea, constipation, intestinal obstruction, intussuception and life-threatening gastrointestinal bleeding. We report herein a case of gastric lipoma with bleeding in a 43-year-old man. The gastroscopy showed a $4{\times}4$ cm ulcero-fungating submucosal mass at the anterior wall of the gastric antrum. Laparoscopic gastric wedge resection was performed and the lesion was diagnosed as gastric lipoma.

• Radiation Oncology Journal
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• 제2권1호
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• pp.25-32
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• 1984

The pathological changes of stomach of the rat following 1,000 rad and 1,800 rad single exposure by Cobalt-60 has been made with 50 experimental rats. The dose of 1,000 rad and 1,800 rad single exposure were equivalent of biologic effect of 2,500 rad in 2 1/2 weeks and 6,000 rad in 6 weeks. Following single exposure, the groups of rat were terminated in 1, 2, 4, 8, 12 weeks intervals and the stomach were fixed to formalin solution immediatly after dissection. The pathological changes were as follows : 1. Following 1,000 rad single exposure, the stomach show only mild to moderate submucosal edema in 4,8,12 weeks group. 1 and 2 weeks group show no changes. 2. Following 1,800 rad single exposure, $32\%(8/25)$ of rats were dead by radiation effect and all other groups of stomach revealed variable pathological changes such as submucosal edema, squamous dysplasia, squamous papilloma as well as squamous cell carcinoma. 3. Optimal tolerance dose to the stomach was $4,500\~5,000$rad when irradiation given by supervoltage. The entire stomach was included within the irradiation field, the dose to the stomach should not exceed 6,000 rad. 4. In conclusion, the radiation injury to the stomach were more direct radiation effects to the gastric mucosa rather than secondary changes of radiation injured vessels.

• Journal of Chest Surgery
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• 제39권11호
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• pp.875-878
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• 2006

39세 남자 환자가 건강검진에서 발견된 식도 점막하 종양을 주소로 내원하였다. 술 전 검사에서 평활근종으로 추정되어 눈종양적출술로 완전 절제를 시행하였다. 술 후 조직, 면역조직화학염색 등의 병리학적 진단으로 얼기형 신경집종으로 확진되었다. 얼기형 신경집종은 얼기형 또는 다결절 형태를 가지며 신경집종의 한 변형으로 매우 드물다. 본 논문은 식도에 드물게 생기는 얼기형 신경집종의 증례로, 다수의 관련된 논문과 함께 치험을 보고하는 바이다.

• 대한기관식도과학회지
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• 제19권1호
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• pp.15-18
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• 2013

Esophageal foreign body is common condition for visit emergency room, and most of them were successfully removed with endoscopy. However, in case of esophageal foreign body impaction, it can be difficult to localize the foreign body. We report a 29-year old man with esophageal foreign body impaction. We successfully localized and removed the esophageal submucosal foreign body using rigid endoscopy under C-arm guidance, avoiding more invasive procedure. The patient was followed up without any complication.