• Bulletin of the Korean Chemical Society
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• 제33권1호
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• pp.149-152
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• 2012

The (S)-(+)-decursin and its analogues are reported as potent inhibitors of melanin production in B16 murine melanoma cells. In order to understand the factors responsible for potency as well as inhibition of potency of (S)-(+)-decursin and its analogues, three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were performed. Since receptor structures are not available, a pharmacophore model was constructed. Using PHASE, we generated 3 different models and selected the seven-site model, which returned excellent statistical values ($r^2$ = 0.9127, $Q^2$ = 0.6878, Pearson-R = 0.9014). Using the generated pharmacophore model, we screened a natural products library and obtained 4'-epi-decursin as the most related compound. 4'-epidecursin is similar to (S)-(+)-decursin, but shows additional interaction possibilities with tyrosinase. The study thus sheds some light on possibility of developing more potent tyrosinase inhibitors.

• Smart Structures and Systems
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• 제4권5호
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• pp.605-628
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• 2008

In bridge structures, damage may induce an additional deflection which may naturally contain essential information about the damage. However, inverse mapping from the damage-induced deflection to the actual damage location and severity is generally complex, particularly for statically indeterminate systems. In this paper, a new load concept, called the positive-bending-inspection-load (PBIL) is proposed to construct a simple inverse mapping from the damage-induced deflection to the actual damage location. A PBIL for an inspection region is defined as a load or a system of loads which guarantees the bending moment to be positive in the inspection region. From the theoretical investigations, it was proven that the damage-induced chord-wise deflection (DI-CD) has the maximum value with the abrupt change in its slope at the damage location under a PBIL. Hence, a novel damage localization method is proposed based on the DI-CD under a PBIL. The procedure may be summarized as: (1) identification of the modal flexibility matrices from acceleration measurements, (2) design for a PBIL for an inspection region of interest in a structure, (3) calculation of the chord-wise deflections for the PBIL using the modal flexibility matrices, and (4) damage localization by finding the location with the maximum DI-CD with the abrupt change in its slope within the inspection region. Procedures from (2)-(4) can be repeated for several inspection regions to cover the whole structure complementarily. Numerical verification studies were carried out on a simply supported beam and a three-span continuous beam model. Experimental verification study was also carried out on a two-span continuous beam structure with a steel box-girder. It was found that the proposed method can identify the damage existence and damage location for small damage cases with narrow cuts at the bottom flange.

• 한국전자거래학회지
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• 제10권4호
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• pp.35-52
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• 2005

IT기술의 발전으로 e비즈니스가 확대됨에 따라 외부 기업과의 협업이 강조되고 있다. 일반적으로 협업에 대한 연구는 비즈니스적, 기술적 표준을 어떻게 설정하는가에 대한 방법론을 중심으로 다루어지고 있다. 하지만 현실적으로 시장 환경에서 협업은 기업의 힘에 의해 결정된다. 이러한 시각에서 본 연구는 기업이 힘의 균형을 이루고 있을 때, 효과적으로 동등한 수준의 협업을 이끌어 낼 수 있는 방안을 살펴보고 이를 적용한 사례를 소개하고자 한다.

• 한국측량학회지
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• 제39권5호
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• pp.297-311
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• 2021

Around the world, there is an increasing interest in Digital Twin cities. Although geospatial data is critical for building a digital twin city, currently-established spatial data cannot be used directly for its implementation. Integration of geospatial data is vital in order to construct and simulate the virtual space. Existing studies for data integration have focused on data transformation. The conversion method is fundamental and convenient, but the information loss during this process remains a limitation. With this, standardization of the data model is an approach to solve the integration problem while hurdling conversion limitations. However, the standardization within indoor space data models is still insufficient compared to 3D building and city models. Therefore, in this study, we present a comparative analysis of data models commonly used in indoor space modeling as a basis for establishing a generic indoor space feature model. By comparing five models of IFC (Industry Foundation Classes), CityGML (City Geographic Markup Language), AIIM (ArcGIS Indoors Information Model), IMDF (Indoor Mapping Data Format), and OmniClass, we identify essential elements for modeling indoor space and the feature classes commonly included in the models. The proposed generic model can serve as a basis for developing further indoor feature models through specifying minimum required structure and feature classes.

• 한국지진공학회논문집
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• 제8권2호
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• pp.19-25
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• 2004

일반적으로 운동방정식을 풀기 위해 많이 이용되는 선형근사모델은 계산이 용이한 반면에 큰 변형상태에서는 그 오차가 커지는 단점이 있다. 따라서 엄밀한 구조물의 응답해석을 위해서는 물성과 기하에 대한 비선형성을 고려해야 한다. 또한, 강과 같이 연성이 큰 재료는 소성 변형을 일으키면서 소산되는 에너지의 대부분이 열로 변하게 되며, 이 열은 열역학 제1 법칙과 2 법칙에 따라 다른 부분으로 전달된다. 이렇게 전달된 열은 온도를 상승시켜 재료의 강도를 약화시키는 역할을 하며, 이것이 다시 구조물의 응답에 영향을 미친다. 본 논문에서는 지진 등의 큰 하중을 받거나 화재로 인한 열 하중을 받는 강구조물의 비선형 대 변형 현상을 적절히 해석할 수 있는 열-탄소성 물성모델을 제안하고 3차원 유한요소해석을 수행하려다.

• Journal of electromagnetic engineering and science
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• 제2권1호
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• pp.11-15
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• 2002

In this paper, we have proposed the new configuration of wideband antenna using CPW fred lines. The proposed antenna has CPW feed lines and U-slot to achieve wade bandwidth with good impedance matching. The use of CPW feed line can decrease the number of substrates. It is compared with the conventional antenna find by a microstrip fled line. The parameters of CPW fred lines were studied by using the quasi-static approximation which is based on the conformal mapping method. The analysis of CPW discontinuities such as the tapered-step structure and the open ended gap were studied by using the quasi-static approximation which is based on the boundary element method. Also, the equivalent circuit model of multi-layer antenna were proposed using the cavity model. Experiment results of the proposed antenna 7how wide-bandwidth characteristics and good radiation patterns in passband.

• Spatial Information Research
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• 제3권1호
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• pp.65-80
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• 1995

GIS는 지난 몇 십년간 컴퓨터 하드웨어 처리기술 발달과 가격인하로 인해 급속히 발달해 왔다. 그러나 GIS는 지도제작산업이나 시설물 관리와 같은 단순한 정보처리 면에서는 탁월한 기능을 보였으나 분석능력면에서는 아직도 미약한 상태이고 또 한편으로는 현실세계의 복잡성을 제대로 반영하지 못한다는 비판을 받고 있다. 본 연구에서는 첫째 통계분석을 이용한 주택가 분석모델을 GIS에 연계시켰으며, 둘째 다핵구조적 도시특성과 GIS를 이용한 도로망에 따른 거리계산등 현실세계의 복잡성을 주택가 분석모델에 반영하였으며, 셋째 서로 다른 분석단위(센서스 트랙과 블럭 그룹) 데이타 사용에 따른 주택가격모델의 다양성을 검증해 보았다.

• 한국언어정보학회지:언어와정보
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• 제2권1호
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• pp.1-41
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• 1998

Evaluation of multilingual translation fundamentally involves measurement of meaning equivalences between the formally mapped discourses/texts of SL(source language) and TL(target language) both represented by a metalanguage called IL(interlingua). Unlike a usaal uni-directional MT(machine translation) model(e.g.:SL $\rightarrow$ analysis $\rightarrow$ transfer $\rightarrow$ generation $\rightarrow$ TL), a bi-directional(by 'negotiation') model(i.e.: SL $\rightarrow$ IL/S $\leftrightarrow$ IL $\leftrightarrow$ IL/T \leftarrow TL) is proposed here for the purpose of evaluating multilingual, not merely bilingual, translation. The IL, as conceived of in this study, is an English-based predicate logic represented in the framework of MRS(minimal recursion semantics), an MT-oriented off-shoot of HPSG(Head-driven Phrase Structure Grammar). In addition, a list of semantic and pragmatic checkpoints are set up, some being optional depending on the kind and use of the translation, so sa to have the evaluation of translation fine-grained by computing matching or mismatching of such checkpoints.

• 한국멀티미디어학회논문지
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• 제24권2호
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• pp.186-198
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• 2021

Security control using surveillance cameras is established when people observe all surveillance videos directly. However, this task is labor-intensive and it is difficult to detect all abnormal situations. In this paper, we propose a deep neural network model, called AT-Net, that automatically detects abnormal situations in the surveillance video, and introduces an automatic video surveillance system developed based on this network model. In particular, AT-Net alleviates the ambiguity of existing abnormal situation detection methods by mapping features representing relationships between people and objects in surveillance video to the new tensor structure based on sparse coding. Through experiments on actual surveillance videos, AT-Net achieved an F1-score of about 89%, and improved abnormal situation detection performance by more than 25% compared to existing methods.

• 한국정보통신학회논문지
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• 제11권5호
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• pp.991-996
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• 2007

최근 3차원 디스플레이 기술로서 유망한 집적 영상 기술을 이용하여 3차원 물체에 대한 컴퓨터 재생 방식이 활발히 연구되고 있다. 이 방식은 집적 영상 기술로 픽업되는 요소 영상을 가상의 핀홀 배열 모델을 이용하여 컴퓨터적으로 특정한 거리의 재생 평면에 확대 중첩함으로서 3차원 영상을 효과적으로 재생하는 방식이다. 그러나 많은 수의 요소 영상은 일반적으로 사각형의 구조를 가지기 때문에 확대 중첩될 경우에 재생 영상에서 격자 구조의 밝기 불균일 문제로 인한 해상도를 떨어뜨리는 문제가 존재하였다. 본 논문에서는 이러한 문제점을 극복하기 위해서 원형 매핑 모델에 기초한 컴퓨터 집적 영상 재생 방식을 제안한다. 제안하는 방식은 기존의 방식에서 발생하는 3차원 재생 영상에서의 불균일 문제를 극복할 수 있으며 3차원 영상의 해상도를 개선할 수 있다. 제안된 방식의 유용함을 보이기 위해서 컴퓨터적 모의 실험과 광학적 실험을 수행하고 그 결과를 보고한다.