• Journal of Korean Neurosurgical Society
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• v.62 no.2
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• pp.183-192
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• 2019

Objective : The objective of this study was to analyze patient-specific blood flow in ruptured aneurysms using obtained non-Newtonian viscosity and to observe associated hemodynamic features and morphological effects. Methods : Five patients with acute subarachnoid hemorrhage caused by ruptured posterior communicating artery aneurysms were included in the study. Patients' blood samples were measured immediately after enrollment. Computational fluid dynamics (CFD) was conducted to evaluate viscosity distributions and wall shear stress (WSS) distributions using a patient-specific geometric model and shear-thinning viscosity properties. Results : Substantial viscosity change was found at the dome of the aneurysms studied when applying non-Newtonian blood viscosity measured at peak-systole and end-diastole. The maximal WSS of the non-Newtonian model on an aneurysm at peak-systole was approximately 16% lower compared to Newtonian fluid, and most of the hemodynamic features of Newtonian flow at the aneurysms were higher, except for minimal WSS value. However, the differences between the Newtonian and non-Newtonian flow were not statistically significant. Rupture point of an aneurysm showed low WSS regardless of Newtonian or non-Newtonian CFD analyses. Conclusion : By using measured non-Newtonian viscosity and geometry on patient-specific CFD analysis, morphologic differences in hemodynamic features, such as changes in whole blood viscosity and WSS, were observed. Therefore, measured non-Newtonian viscosity might be possibly useful to obtain patient-specific hemodynamic and morphologic result.

• Composites Research
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• v.35 no.6
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• pp.425-430
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• 2022

In this study, the mechanical properties of the pressure vessel composite exposed to the thermal environment were evaluated to establish the standard for high temperature static pressure test of the pressure vessel for hydrogen bus. As the tensile strength of the composite material approaches the glass transition temperature of the epoxy resin, the strength decreases due to the deterioration of the epoxy resin. In addition, it was confirmed that the tensile strength increased again due to the post-curing of the epoxy resin during long-term exposure. Therefore, the accelerated stress rupture test conditions of the pressure vessel for the hydrogen bus should be set based on the epoxy resin properties of the carbon fiber composite material.

• Journal of the Korean Geotechnical Society
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• v.25 no.2
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• pp.5-15
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• 2009

The conventional reinforced earth retaining wall has the connector system to fix the reinforcement and block. However, this system defect may cause the crack of block and the rupture of reinforcement due to the stress concentration near the face of reinforced earth retaining wall. Hence, the new connector system which was able to allow the settlement of reinforcement was developed in this study and a test was carried out in the study area which is divided into the conventional reinforced earth retaining wall and reinforced Earth Retaining Wall driving the settlement. As the results of field monitoring in situ, the ratio of tensile force calculated at maximum value on contiguous portion of front block showed that the settlement type decreased the stress concentration near the face of front block greater than the conventional type.

• Journal of Korean Foot and Ankle Society
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• v.26 no.1
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• pp.16-21
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• 2022

When an ankle lateral malleolar fracture is accompanied by a deltoid ligament rupture without a medial malleolar fracture, such an injury is called a bimalleolar equivalent fracture. This means that even if there is no bony injury on the medial side, there may be functional instability of the ankle joint due to damage to the deltoid ligament. Manual or gravity external rotational stress radiography is used to differentiate an ankle bimalleolar equivalent fracture from an isolated lateral malleolar fracture. If the medial joint gap is widened on the stress radiography, the deltoid ligament injury can be diagnosed, and surgical treatment for fibula fractures is recommended. After open reduction of the fibula fracture (with syndesmotic fixation if needed), a decision on the repair of the deltoid ligament is taken depending on the surgeons' preference and intraoperative findings. The deltoid ligament repair is performed by inserting a suture anchor (or anchors) in the medial malleolus and fixing the deep and superficial deltoid ligaments to the medial malleolus. The only randomized study to evaluate the utility of deltoid ligament sutures in ankle fractures did not support the deltoid ligament suture, but the study itself had many limitations. An appropriately powered, randomized, controlled trial of the deltoid ligament repair with both patient-reported outcome and radiographic outcome evaluation is needed in the future.

• Korean Journal of Materials Research
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• v.24 no.10
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• pp.526-531
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• 2014

Thermal shock resistance property has recently been considered to be one of the most important basic properties, in the same way that the transverse-rupture property is important for sintered hard materials such as ceramics, cemented carbides, and cermets. Attempts were made to evaluate the thermal shock resistance property of 10 vol% TaC added Ti(C,N)-Ni cermets using the infrared radiation heating method. The method uses a thin circular disk that is heated by infrared rays in the central area with a constant heat flux. The technique makes it possible to evaluate the thermal shock strength (Tss) and thermal shock fracture toughness (Tsf) directly from the electric powder charge and the time of fracture, despite the fact that Tss and Tsf consist of the thermal properties of the material tested. Tsf can be measured for a specimen with an edge notch, while Tss cannot be measured for specimens without such a notch. It was thought, however, that Tsf might depend on the radius of curvature of the edge notch. Using the Tsf data, Tss was calculated using a consideration of the stress concentration. The thermal shock resistance property of 10 vol% TaC added Ti(C,N)-Ni cermet increased with increases in the content of nitrogen and Ni. As a result, it was considered that Tss could be applied to an evaluation of the thermal shock resistance of cermets.

• BMB Reports
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• v.48 no.6
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• pp.303-312
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• 2015

Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is an essential protein in the "programmed", or "regulated" necrosis cell death pathway that is activated in response to death receptor ligands and other types of cellular stress. Programmed necrotic cell death is distinguished from its apoptotic counterpart in that it is not characterized by the activation of caspases; unlike apoptosis, programmed necrosis results in plasma membrane rupture, thus spilling the contents of the cell and triggering the activation of the immune system and inflammation. Here we discuss findings, including our own recent data, which show that RIP3 protein expression is absent in many cancer cell lines. The recent data suggests that the lack of RIP3 expression in a majority of these deficient cell lines is due to methylation-dependent silencing, which limits the responses of these cells to pro-necrotic stimuli. Importantly, RIP3 expression may be restored in many cancer cells through the use of hypomethylating agents, such as decitabine. The potential implications of loss of RIP3 expression in cancer are explored, along with possible consequences for chemotherapeutic response. [BMB Reports 2015; 48(6): 303-312]

• Journal of computational fluids engineering
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• v.16 no.4
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• pp.64-71
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• 2011

Cerebral aneurysm mostly occurs at a bifurcation of the circle of Willis. When the cerebral aneurysm is ruptured, a disease like subarachnoid hemorrhage and stroke is caused and this can be even deadly for patients. Generally it is known that causes of the intracranial aneurysm are a congenital deformity of the artery and pressure or shear stress from the blood flow. A blood flow pattern and the geometry of the blood vessel are important factors for the aneurysm formation. Research for several hemodynamic indices has been performed and these indices can be used for the prediction of aneurysm initiation and rupture. Therefore, the numerical analysis was performed for hemodynamic characteristics of the blood flow through the cerebral artery applying the various bifurcation angle and flow rate ratio. We analyze the flow characteristics using indices from the results of the numerical simulation. In addition, to investigate the flow pattern in the aneurysm according to the bifurcation angle and the flow rate ratio, we performed the numerical simulation on the supposition that the aneurysm occurs.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.6
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• pp.669-676
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• 2014

A three-way catalyst substrate for domestic passenger car satisfies the design criteria for exhaust gas exchange and pressure drop but does not have satisfactory thermal fatigue performance. Prefracture faults in this three-way catalyst substrate has often been discovered in vehicle repair or vehicle inspection facilities. This paper presents a thermal fatigue performance estimation method for a three-way catalyst substrate using a probabilistic strength reduction factor model. This method is superior to the thermal fatigue performance estimation method for a three-way catalyst substrate that uses a deterministic strength model.

• Journal of the Korean Ceramic Society
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• v.52 no.1
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• pp.23-27
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• 2015

Recently, the use of ion-exchange strengthened glass has increased sharply, as it is now used as the cover glass for smart phone devices. Therefore, many researchers are focusing on methods that can be used to strengthen ion-exchange glass. However, research on how the improved strength can be maintained under thermal environment of device manufacturing is still insufficient. We tested the degradation of the characteristics of ion-exchange soda-lime glass samples, including their surface compressive stress characteristics, the depth of the ion-exchange layer (DOL), flexural strength, hardness, and modulus of rupture (MOR) values. Degradation of the characteristics of the ion-exchange glass samples occurred when they were heat-treated at a temperature that exceeded $350^{\circ}C$.

• Journal of Ocean Engineering and Technology
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• v.12 no.2 s.28
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• pp.65-70
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• 1998

In this report, the creep properties and creep life estimation by Larson-Miller Parameter(LMP) Method for 2.25Cr1Mo steel to be used as power plant tubes or other components were presented at the high temperatures of 500, 550, and $600^{\circ}C$. It was confirmed experimentally and quantitatively that a creep life estimation equation at such various high temperatures was well derived by LMP and could be used very effectively within the creep life of 10$^3$ hours, but very unreliable and even dangerous for design in a long term of creep life such as 10$^4$ or $10^5$ hours.