• The Journal of the Korean dental association
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• v.57 no.3
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• pp.162-168
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• 2019

Composite resin restorations in posterior teeth are increasing due to the aesthetic needs of patients and the development of materials. This trend will accelerate in line with domestic insurance policies. However, resin composites generate stresses due to their contraction during the polymerization process. To reduce the polymerization shrinkage stress of resin composites, incremental layering technique has been recommended for decades. This technique reduces stress at the cavity wall interface and allows a more efficient light curing of the material. Bulk-fill resin composites have been designed to simplify the restorative technique because they can be placed into cavities in a single increment of 4-5mm. The simplification of the operative procedures is desirable in clinical daily practice. In this context, bulk-fill resin composites are an attractive alternative for posterior restorations. However, a clearer understanding of the clinical performance of this relatively new class of materials in comparison to conventional resin composites is required. Based on previous studies, the aim of the current review was to present the clinical criteria for the use of bulk-fill composites in direct restorations of posterior teeth.

• Geomechanics and Engineering
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• v.35 no.2
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• pp.135-147
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• 2023

Sand columns in clayey soil are considered one of the most economical and environmentally-friendly soil-improving techniques. It improves the shear strength parameters, reduces the settlement, and increases the bearing capacity of clayey soils. The aim of this paper is to study the effect of grain shape in sand columns on their performance in improving the mechanical properties of clayey soils. An intensive series of consolidated-drained triaxial tests were performed on clay specimens only and clay specimens with sand columns. The parameters examined during the experimental work were grain shape in sand columns (angular, rounded, sub-rounded) and effective confining pressure (50 kPa, 100 kPa, 200 kPa). The results indicated that there is a significant improvement in the deviatoric stress and stiffness values of specimens with sand columns. Improving deviatoric stress values in the use of angular sand grains was found to be higher than those in the use of sub-rounded and rounded sand grains. A 187%, 159%, and 153% increment in deviatoric stress values were observed for the sand columns with angular, sub-rounded, and rounded grain shapes, respectively. The specimens were observed to be more contractive as the sand column was installed, and as the angularity of grains in the sand column was increased. Sand column installation improves significantly the angle of internal friction, and the effective angle of internal friction increases as the angularity of the sand grains increases.

• Magazine of the Korea Concrete Institute
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• v.11 no.2
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• pp.77-84
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• 1999

Recently, it is increased the use of High-Strength Light-Weight Concrete(HLC) in the high-rise buildings and mega-structures. But there are a few research on the bond behavior of HLC, so it need to study about that. The present study was performed to investigate the bond characteristics of HLC. Major test variables include concrete compressive strength(f'c), concrete cover(c), bond length (${\ell}_{db}$), and bar diameter($d_b$). Test results indicate that the bond stress of HLC is increased with the increment of $\sqrt{f'_c}$ and concrete cover, bond stress is decreased with increment of bond length and bar diameter. And the final failure mode such as splitting or pullout failure is significantly affected by the concrete cover to bar diameter ratios(C/$d_b$). Test results were compared with ACI code and other proposed equations. The bond stress of HLC is higher than that of normal-strength normal-weight concrete, but lower than that of high-strength normal-weight concrte. Considering the present test results, modification factor(${\lambda}$= 1.3) of bond length in ACI 318-95 code for light-weight concrete is may have to be reviewed to apply to HLC.

• Journal of Ocean Engineering and Technology
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• v.13 no.3 s.33
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• pp.108-113
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• 1999

In this study, CT specimens were prepared from ASTM A516 Gr. 65 which was used for pressure vessel plates for moderate and lower temperature service. Fatigue crack growth test was carried out in the environment of low temperature of $10^{circ}C, -10^{circ}C, -30${circ}C\;and\;-50^{circ}C$ and in the range of stress ratio of R=0.05 and 0.3 by means of opening mode displacement. Based on these test results, the characteristics from temperature and stress ration were shown as follows. 1) As the stress ratio, R increased da/dN and ${Delta}K$ of 2nd stage gradually decreased. And as R decreased, the effect of temperature became greater and greater. 2) As the temperature descended, da/dN decreased on a certain ${Delta}K$, and ${Delta}K$ did in a same da/dN. And the stress ratio, R exerted greater influence at the lower temperature. 3) The fatigue crack growth constant, m increased at $10^{circ}C$ and $-10^{circ}C$, snd decreased at $-30^{circ}C$ and $-50^{circ}C$ following the increment of stress ratio R. And m increased along with the reduction of temperature greatly decreased at $-30^{circ}C$ to come close to two(2).

• Journal of Oriental Neuropsychiatry
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• v.28 no.3
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• pp.183-194
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• 2017

Objectives: Chijasitang (CJST) has been prescribed for patients with anxiety disorder, and is believed to treat insomnia. The present study was carried out to investigate whether Fructus Gardeniae, Fermented Semen Sojae Preparatum and CJST have beneficial effects on treating anti-stress. Methods: The mice were divided into the following groups: normal, control, positive control, and experimental. Then, the experimental groups were further divided into the Fructus Gardeniae group (FG), the Fermented Semen Sojae Preparatum group (FS), the Chijasitang water extract group (CJSTW), and the Chijasitang 30% ethanol extract group (CJSTE). In the positive control group, a single dose of imipramine ($500{\mu}g/g$) was applied to the mice. In the experimental groups, each single dose of FG, FS, CJSTW and CJSTE ($50{\mu}g/g$) was applied to the mice. After one hour, the mice in all groups except the normal group were exposed to immobilization stress. Their body weights, phagocytosis, nitric oxide in macrophage, corticosterone, and adrenocorticotropic hormone (ACTH) were observed. Results: Fructus Gardeniae, Fermented Semen Sojae Preparatum and Chijasitang prevented weight loss and suppressed the decrease of phagocytosis in the mice after their exposure to immobilization-stress. Although they did not influence the amount of NO, they suppressed the increment of ACTH and corticosterone in the immobilization-stressed mice. Conclusions: According to the results of this study, they suggest that Fructus Gardeniae, Fermented Semen Sojae Preparatum and Chi-Ja-Si-Tang all have some anti-stress effects.

• Journal of the Korean GEO-environmental Society
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• v.11 no.4
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• pp.19-24
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• 2010

Generally, slope behavior is analyzed by 2-dimensional creep model. Creep behavior shows the deformation variation as time goes by without stress increment. Convention 2-dimensional creep analysis does not have the term of stress variation, it means creep analysis could not figure out the relationship of shear strength variation according to the stress variation and displacement. The slope weight and shear strength is directly related and interlocked to the safety variation and displacement of slope, therefore, this phenomenon could be treated and analyzed as combining the hysteresis and creep, the iteration of this process will result in the slope safety. Furthermore, the combined analysis will be the slope analysis considering shear stress, displacement and shear strength with time variation. In real case, because the variation of shear stress and strength happen at the same time, they should be changed into safety factor which is function of them. This paper shows the 3-dimensional variation of unit weight of soil with hybrid analysis considering creep and hysteresis on the seepage and drainage of rainfall, futhermore variations of shear stress and strength which make the safety factor change.

• Journal of Power System Engineering
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• v.3 no.2
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• pp.51-56
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• 1999

Fatigue crack propagation rates and characteristics of the SA516-70 steel which is used for the low temperature pressure vessels, were studied in the room temperature of $10^{\circ}C$ and low temperature ranges of $-10^{\circ}C,\;-30^{\circ}C,\;-50^{\circ}C,\;and\;-70^{\circ}C$ with stress ratio of R=0.05. The obtained experimental results are as follows; 1) In the logarithmic relationship between the fatigue crack propagation rate(da/dN) and stress intensity factor K, the linear relationship was obtained up to da/dN > $8{\times}10^3$ mm/cycle in the same of room temperature, but in low temperature case, the relationship was extended to the range of low crack propagation rate. 2) The lower limit stress intensity factor of SA516-70 ${\Delta}K_{th}\;was\;23MPa\sqrt{m}$ and in the case of low temperature $-50^{\circ}C\;and\;-70^{\circ}C$, the crack propagation rate da/dN which showed a linear relation, reached rapidly to the ${\Delta}K_{th}$. As the results, the crack propagation rates of $-50^{\circ}C\;and\;-70^{\circ}C$ were lower than that of room temperature and according to the testing temperature the rates were decreased rapidly to the ${\Delta}K_{th}$. 3) On the relationship between the stress intensity factor ${\Delta}K$ and the track propagation cycle, the stress intensity factors of low cycle region was rapidly increased at low temperature, but ${\Delta}K$ was increased rapidly at room temperature of high cycle. 4) On the relationship between the fatigue crack propagation rate and cycle, the fatigue crack propagation rate showed higher gradient in the room temperature than the low temperature due to the increment in ductility at low temperature.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2000.10a
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• pp.240-245
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• 2000

Fatigue crack propagation rates and characteristics of the SA516-60 steel which is used for the low temperature pressure vessels, were studied in the room temperature of $25^{\circ}C$ and low temperature ranges of $10^{\circ}C,\; -10^{\circ}C,\; -30^{\circ}C,\; -50^{\circ}C, \;and\; -70^{\circ}C4 with stress ratio of R=0.05. The obtained experimental results are as follows; 1) In the logarithmic relationship between the fatigue crack propagation rate(da/dN) and stress intensity factor K, the linear relationship was obtained up to da/dN 〉$8\times10^{-3}$/mm/cycle in the same of room temperature, but in low temperature case, the relationship was extended to the range of crack propagation rate. 2) The lower limit stress intensity factor of SA516-60 $\DeltaK_{th}$ was 15.8MPa and in the case of low temperature $-50^{\circ}C\; and\; -70^{\circ}C$, the crack propagation rate da/dN which showed a linear relation, reached rapidly to the $\DeltaK_{th}$/. As the results, the crack propagation rates of $-50^{\circ}C\; and\; -70^{\circ}C$ were lower than that of room temperature and according to the testing temperature the rates were decreased rapidly to the $\DeltaK_{th}$/. 3) On the relationship between the stress intensity factor $\DeltaK$ and the crack propagation cycle, the stress intensity factors of low cycle region was rapidly increased at low temperature, but $\DeltaK$ was increased rapidly at room temperature of high cycle. 4) On the relationship between the fatigue crack propagation rate and cycle, the fatigue crack propagation rate showed higher gradient in the room temperature than the low temperature due to the increment in ductility at low temperature.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5343-5348
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• 2015

Promoter hypermethylation of the runt-related transcription factor 3 (RUNX3) gene is associated with increased risk of hepatocellular carcinoma (HCC). Oxidative stress plays a vital role in both carcinogenesis and progression of HCC. However, whether oxidative stress and RUNX3 hypermethylation in HCC have a cause-and-effect relationship is not known. In this study, plasma protein carbonyl and total antioxidant capacity (TAC) in patients with hepatitis B virus (HBV)-associated HCC (n=60) and age-matched healthy subjects (n=80) was determined. RUNX3 methylation in peripheral blood mononuclear cells (PBMC) of subjects was measured by methylation-specific PCR. Effect of reactive oxygen species (ROS) on induction of RUNX3 hypermethylation in HCC cells was investigated. Plasma protein carbonyl content was significantly higher, whereas plasma TAC was significantly lower, in HCC patients than healthy controls. Based on logistic regression, increased plasma protein carbonyl and decreased plasma TAC were independently associated with increased risk for HCC. PBMC RUNX3 methylation in the patient group was significantly greater than in the healthy group. RUNX3 methylation in hydrogen peroxide ($H_2O_2$)-treated HepG2 cells was significantly higher than in untreated control cells. In conclusion, increase in oxidative stress in Thai patients with HBV-associated HCC was demonstrated. This oxidative increment was independently associated with an increased risk for HCC development. RUNX3 in PBMC was found to be hypermethylated in the HCC patients. In vitro, RUNX3 hypermethylation was experimentally induced by $H_2O_2$. Our findings suggest that oxidative stress is a cause of RUNX3 promoter hypermethylation in HCC cells.

• Journal of Yeungnam Medical Science
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• v.20 no.1
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• pp.36-44
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• 2003

Background: To evaluate the efficacy of EMG biofeedback and pelvic floor electrical stimulation in the stress urinary incontinence patients by Kontinence HMT2000. Materials and Methods: A group of 14 patients with stress urinary incontinence were treated with combined biofeedback and intravaginal electrical stimulation during 12 sessions from 2 weeks to 6 weeks. Results: At immediate post treatment, subjective cure rate was 28% and improvement rate was 57% and failure rate was 15%. Thus the overall success rate for this treatment was 85%. The result of 3 months after treatment showed cure rate 14% and improvement rate was 43%. Intravaginal pressure increased by an average of 11.9 cmH2O. Increased vaginal pressure was found in 93% of the patients and more than 50% increment of intravaginal pressure was 71%. Conclusions: Combined biofeedback and pelvic floor electrical stimulation by use of Kontinence HMT2000 is effective for the patients who have good compliance, relative low degree stress urinary incontinence. In order to attain good results, a well structured program that teaches specific muscle exercise and the patients should be followed by regular interval reinforcement treatment.