• Title/Summary/Keyword: Strength Of Evidence

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Effect of PVA Concentration on Strength and Cell Growth Behavior of PVA/gelatin Hydrogels for Wound Dressing

  • Kim, Soyeun;Lim, Hyunju;Kim, Sojeong;Lee, Deuk Yong
    • Journal of Biomedical Engineering Research
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    • v.41 no.1
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    • pp.1-7
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    • 2020
  • Polyvinyl alcohol (PVA)/gelatin hydrogels were prepared by repeating freezing/thawing three times to evaluate the influence of PVA concentration on the strength and the cell growth behavior of the PVA/gelatin hydrogels. The swelling rate of the PVA/gelatin hydrogels decreased with raising the PVA content from 6 wt% to 12 wt% due to the formation of 3-D network inside the hydrogel. No appreciable degradation of the hydrogels was detected. As the PVA content increased from 6 wt% to 12 wt%, the strength of the PVA/gelatin hydrogels increased drastically from 6.4±0.9 kPa to 46.6±9.0 kPa. The PVA/gelatin hydrogels did not show any evidence of causing cell lysis or toxicity, implying that the hydrogels are clinically safe and effective. Although the strength increased with increasing the PVA content, the PVA/gelatin hydrogels containing 8 wt% exhibited the fastest cell growth, which is highly suitable for wound dressing requiring fast healing regeneration.

Effects of a Muscle Strength Reinforcement Exercise Program for Older Adult Patients on Hemodialysis (노인 혈액투석 환자를 위한 근력강화 운동 프로그램의 효과)

  • Lee, Jena
    • Journal of Korean Gerontological Nursing
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    • v.20 no.3
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    • pp.204-216
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    • 2018
  • Purpose: The purpose of this study was to examine effects of a muscle strength reinforcement exercise program (MSREP) for older adult patients with hemodialysis (OAPHD) which was designed to improve health status and quality of life of these older adult patients. Methods: Participants were 40 patients with OAPHD: 20 in the experimental group and 20 in the control group. MSREP was conducted with the experimental group for 12 weeks at H geriatric hospital. An assessment was done to determine effects on physical performance, inflammation index, fatigue, muscle strength and quality of life. Short physical performance battery, C-Reactive Protein (CRP), visual analog scale for fatigue, object lifting' proposed by the Life Options Rehabilitation Advisory Council, sit-to-stand test, and quality of life index were used to gather data. Results: Between the 2 groups there was no significant difference in scores for physical performance, fatigue or quality of life. However, the 2 groups showed significant difference in CRP values and muscle power scores on post-test. Conclusion: Findings provide evidence for the potential utility of education for older adult patients with hemodialysis. Also, this program could allow these patients to increase muscle strength, and contribute to achieving better health conditions in OAPHD care.

Efficiency and accuracy of artificial intelligence in the radiographic detection of periodontal bone loss: A systematic review

  • Asmhan Tariq;Fatmah Bin Nakhi;Fatema Salah;Gabass Eltayeb;Ghada Jassem Abdulla;Noor Najim;Salma Ahmed Khedr;Sara Elkerdasy;Natheer Al-Rawi;Sausan Alkawas;Marwan Mohammed;Shishir Ram Shetty
    • Imaging Science in Dentistry
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    • v.53 no.3
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    • pp.193-198
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    • 2023
  • Purpose: Artificial intelligence (AI) is poised to play a major role in medical diagnostics. Periodontal disease is one of the most common oral diseases. The early diagnosis of periodontal disease is essential for effective treatment and a favorable prognosis. This study aimed to assess the effectiveness of AI in diagnosing periodontal bone loss through radiographic analysis. Materials and Methods: A literature search involving 5 databases (PubMed, ScienceDirect, Scopus, Health and Medical Collection, Dentistry and Oral Sciences) was carried out. A specific combination of keywords was used to obtain the articles. The PRISMA guidelines were used to filter eligible articles. The study design, sample size, type of AI software, and the results of each eligible study were analyzed. The CASP diagnostic study checklist was used to evaluate the evidence strength score. Results: Seven articles were eligible for review according to the PRISMA guidelines. Out of the 7 eligible studies, 4 had strong CASP evidence strength scores (7-8/9). The remaining studies had intermediate CASP evidence strength scores (3.5-6.5/9). The highest area under the curve among the reported studies was 94%, the highest F1 score was 91%, and the highest specificity and sensitivity were 98.1% and 94%, respectively. Conclusion: AI-based detection of periodontal bone loss using radiographs is an efficient method. However, more clinical studies need to be conducted before this method is introduced into routine dental practice.

A Systematic Review on the Treatment of Post-Stroke Patients Based on Sasang Constitutional Medicine (사상의학적 중풍 후유증 치료에 대한 체계적 문헌 고찰)

  • Oh, Hyunjoo;Lee, Jeongyun;Lee, Hyeri;Lee, Junhee
    • Journal of Sasang Constitutional Medicine
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    • v.34 no.2
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    • pp.48-64
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    • 2022
  • Objectives The purpose of this study was to review and evaluate the clinical evidence of the efficacy and safety of treatment based on Sasang constitutional medicine (SCM) for post-stroke patients by systematic review and meta-analysis. Methods Randomized controlled trials (RCTs), published in 10 electronic databases up to December 2020, were searched. For the included studies, Cochrane's risk of bias assessment was performed to analyze the methodological quality. The strength of evidence was evaluated using the grading of recommendations assessment, development, and evaluation system based on the results of analyses. All review processes were performed by two independent researchers. Results Five RCTs were finally included. All included RCTs were conducted for one month on post-stroke patients in 60-80s, four studies on Tae-Eum patients and one study on So-Yang patients. Four types of constitution-specific herbal medicine (Chungpyesagan-tang, Cheongsimsanyak-tang, Yeoldahanso-tang, and Yangkyuksanhwa-tang) and constitution-specific acupuncture therapy were identified as interventions. More than half of the included studies were evaluated as low quality due to the high-risk of bias in selection, performance, and detection. The combination of constitution-specific herbal medicine, acupuncture, and conventional treatment was more effective in improving the patients' motor impairment, dysphagia, aphasia, and depression than conventional treatment alone. No serious adverse events by SCM treatment were reported. Conclusions SCM treatment may improve the sequelae of post-stroke patients safely in combination with conventional treatment. Since the quality of clinical evidence included in this study was low, higher quality clinical evidence obtained in well-designed clinical studies will be needed.

How the Strength of Parent Brand Associations Influences the User Acceptance of Extended brand: Internet of Things Perspective (사용자의 확장브랜드 수용과 모브랜드의 영향력: 사물인터넷을 중심으로)

  • Lim, Hyun A;Kwon, Hyuk-Jun;Choi, Jaewon
    • The Journal of Society for e-Business Studies
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    • v.23 no.2
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    • pp.49-65
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    • 2018
  • The purpose of the research is to identify the effects of brand evidence, brand personality and negative factors on extended brand trust and customer purchase intention in IoT (Internet of Things) service. Negative factors include scarcity marketing and privacy concern. To achieve this objective, we analyzed the 269 respondents who had used Xiaomi products at least more than once. The results of this study are as follows: First, it was found that core service, self-image congruence of brand evidence and brand personality has a positive influence on extended brand trust. But, perceived price of brand evidence is not related to extended brand trust. Secondly, Scarcity marketing influenced extended brand trust. But, Privacy concern is not related to extended brand trust. Consumers did not realize privacy because of technological innovation of IoT. Thus, the research has a different significance from antecedent research.

MOLECULAR BASIS OF LUBRICATION

  • Hsu, S.M.
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 2002.10b
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    • pp.49-50
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    • 2002
  • Rapid advancements in analytical instrumentations and techniques in the last several decades offer an unprecedented opportunity to analyze the complex chemistry and probe the surfaces for chemical evidence. Recent developments in nanotechnology provide further ability to examine phenomena and mechanisms at the nanometer level. As a result of these advances, our understanding of the complex lubrication system has improved significantly. This paper will attempt to provide a molecular basis of how lubricant and additives function in lubrication.

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A New Type of NPI Licensing Context: Evidence from French Subjunctive and NE Expletif

  • Choi, Yoon-Hee
    • Proceedings of the Korean Society for Language and Information Conference
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    • 2007.11a
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    • pp.115-125
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    • 2007
  • The purpose of this paper is to propose a new type of NPI licensing context through French subjunctive and ne expletif. The distribution of NPIs on previous studies does not exactly correspond to negative function types. French subjunctive and ne expletif are good guidelines for reclassifying NPI licensing context. My classification is by a hierarchy of strength in negative force: overtly negative proposition > negative entailment > negative implicature. A new type of NPI licensing context is: (i) I-domain for negative implicature (ⅱ) E-domain for negative entailment and (ⅲ) overt negation.

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Evaluation of dam strength by finite element analysis

  • Papaleontiou, Chryssis G.;Tassoulas, John L.
    • Earthquakes and Structures
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    • v.3 no.3_4
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    • pp.457-471
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    • 2012
  • Current code procedures for stress and stability analysis of new and existing concrete-gravity dams are primarily based on conventional methods of analysis. Such methods can be applied in a straightforward manner but there has been evidence that they may be inaccurate or, possibly, not conservative. This paper presents finite element modeling and analysis procedures and makes recommendations for local failure criteria at the dam-rock interface aimed at predicting more accurately the behavior of dams under hydraulic and anchoring loads.

Acidity Effect on the Catalytic Properties for Phenol Isopropylation

  • Yu, Jeong Hwan;Lee, Cheol Wi;Wang, Bo;Park, Sang On
    • Bulletin of the Korean Chemical Society
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    • v.22 no.3
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    • pp.263-266
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    • 2001
  • Isopropylation of phenol with 2-propanol has been carried out over Na-exchanged ZSM-5 zeolites to determine the effect of catalyst acidity on phenol conversion and product selectivity. The acid type and strength of the catalyst such as Lewis, weak and strong Bronsted acid sites are measured by pyridine adsorbed XPS and the catalytic properties are interpreted in terms of the acid properties. The active site and mechanism for the reaction are suggested based on evidence of study from the reactant adsorbed FT-IR.

Effects of High Energy Radiation on the Mechanical properties of Carbon Fiber/Dpoxy Composites (고에너지 방사선이 탄소섬유/에폭시 복합재료의 기계적 물성에 미치는 영향)

  • 박종신
    • The Korean Journal of Rheology
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    • v.3 no.1
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    • pp.22-29
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    • 1991
  • In an effort to predict the long term durability of carbon fiber/epoxy composites in a space environ-ment interlaminar shear strength (ILSS) of the composites was measured as a function of 0.5 MeV electron radiation dosage. For the ILSS measurements a notch method (ASTM D3846) was used with and without side-supports. the supports were used to prevent peeling or bending during the test. The ILSS of both T300/ 5209 longitudinal composite system increases monotonically with radiation when the test is corried out without the support the ILSS of the composites increases initially but then decreases with further radiation. It is also observed that the ILSS of the unsupported case is much lower than that of the supported case. Measurement of epoxy modulus shows that the elastic modulus increases monotonically with radiation. But the breaking strength of the epoxy decreases with radiation. Electron Spectroscopy for Chemcal Analysis shows that the oxygen contents at both the pure epoxy surface and the composite fracture surface increase with radiation dose resulting in the increase of polarity at the interfacial region. This may be a supporting evidence for the increase in the ILSS of the composites.

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