• Clinical and Experimental Pediatrics
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• 제65권3호
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• pp.142-149
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• 2022

Background: Individuals with Down syndrome present with several impairments such as hypotonia, ligament laxity, decreased muscle strength, insufficient muscular cocontraction, inadequate postural control, and disturbed proprioception. These factors are responsible for the developmental challenges faced by children with Down syndrome. These individuals also present with balance dysfunctions. Purpose: This systematic review aims to describe the motor dysfunction and balance impairments in children and adolescents with Down syndrome. Methods: We searched the Scopus, ScienceDirect, MEDLINE, Wiley, and EBSCO databases for observational studies evaluating the motor abilities and balance performance in individuals with Down syndrome. The review was registered on PROSPERO. Results: A total of 1,096 articles were retrieved; after careful screening and scrutinizing against the inclusion and exclusion criteria, 10 articles were included in the review. Overall, the children and adolescents with Down syndrome showed delays and dysfunction in performing various activities such as sitting, pulling to stand, standing, and walking. They also presented with compensatory mechanisms to maintain their equilibrium in static and dynamic activities. Conclusion: The motor development of children with Down syndrome is significantly delayed due to structural differences in the brain. These individuals have inefficient compensatory strategies like increasing step width, increasing frequency of mediolateral center of pressure displacement, decreasing anteroposterior displacement, increasing trunk stiffness, and increasing posterior trunk displacement to maintain equilibrium. Down syndrome presents with interindividual variations; therefore, a thorough evaluation is required before a structured intervention is developed to improve motor and balance dysfunction.

• Current Photovoltaic Research
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• 제10권2호
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• pp.56-61
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• 2022

Recently, the expansion of the domestic solar market due to the promotion of eco-friendly and alternative energy-related policies is promising, and it is expected to lead the high-efficiency/high-power module market based on M10 or larger cells to reduce LCOE, 540-560W, M12 based on M10 cells Compared to the existing technology with an output of 650-700W based on cells, it is necessary to secure competitiveness through the development of modules with 600W based on M10 cells and 750W based on M12 cells. For the development of high efficiency/high-power n-type bifacial, it is necessary to secure a lightweight technology and structure due to the increase in weight of the glass to glass module according to the large area of the module. Since the mechanical strength characteristics according to the large area and high weight of the module are very important, design values such as a frame of a new structure that can withstand the mechanical load of the Mechanical Load Test and the location of the mounting hole are required. In this study, a structural analysis design model was introduced to secure mechanical reliability according to the enlargement of the module area, and the design model was verified through the mechanical load test of the actual product. It can be used as a design model to secure the mechanical reliability required for PV modules by variables such as module area, frame shape, and the location and quantity of mounting holes of the structural analysis model verified. A relationship of output drop can be obtained.

• 한국구조물진단유지관리공학회 논문집
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• 제27권1호
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• pp.86-94
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• 2023

본 연구에서는 강재 슬릿댐퍼를 대상으로 하여 면외 변형을 구속할 수 있는 보완상세를 제시하고, 제안상세 적용 유무와 댐퍼의 형상비를 변수로 하여 일정진폭 가력실험을 수행하였다. 실험결과에 따라 제안상세가 적용된 슬릿댐퍼의 반복이력은 설정된 변수 범위에서 모두 안정적인 방추형의 이력거동을 나타내었으며 종국거동까지 댐퍼의 면외변형은 관찰되지 않았다. 누적변형각 분석을 통해 제안상세가 적용된 댐퍼 시스템은 대조군에 비해 월등히 큰 소성변형능력을 확보할 수 있음을 확인하였다. 이러한 구조적 효과(구속패널효과)는 슬릿댐퍼의 형상비가 작을수록 크게 나타났다. 관련 국외기준을 참고하여 제안상세 적용유무에 따른 슬릿댐퍼의 피로곡선을 작성하고 예측곡선 제시를 위한 매개변수를 도출하였다. 본 연구의 결과를 토대로 향 후 다양한 종류의 제진장치의 구조성능에 대한 정량적인 비교가 가능할 것으로 판단된다.

• Advances in materials Research
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• 제11권4호
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• pp.375-390
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• 2022

Carbon Fiber Reinforced Polymer (CFRP) composite provides outstanding mechanical capabilities and is therefore popular in the automotive and aerospace industries. Drilling is a common final production technique for composite laminates however, drilling high-strength composite laminates is extremely complex and challenging. The delamination of composites during the drilling at the entry and exit of the hole has a severe impact on the results of the holes surface and the material properties. The major goal of this research is to investigate contemporary industry solutions for drilling CFRP composites: enhanced edge geometries of cutting tools. This study examined the occurrence of delamination at the entry and exit of the hole during the drilling. For each of the 80°, 90°, and 118°point angle uncoated Brad point, Dagger, and Twist solid carbide drills, Taguchi design of experiments were undertaken. Cutting parameters included three variable cutting speeds (100-125-150 m/min) and feed rates (0.1-0.2-0.3 mm/rev). Brad point drills induced less delamination than dagger and twist drills, according to the research, and the best cutting parameters were found to be a combination of maximum cutting speed, minimum feed rate, and low drill point angle (V:150 m/min, f: 0.1 mm/rev, θ: 80°). The feed rate was determined to be the most efficient factor in preventing hole entry and exit delamination using analysis of variance (ANOVA). Regression analysis was used to create first-degree mathematical models for each cutting tool's entrance and exit delamination components. The results of optimization, mathematical modelling, and experimental tests are thought to be reasonably coherent based on the information obtained.

• Journal of Genetic Medicine
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• 제19권2호
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• pp.63-75
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• 2022

Purpose: Osteoporosis is a common calcium and metabolic skeletal disease which is characterized by decreased bone mass, microarchitectural deterioration of bone tissue and impaired bone strength, thereby leading to enhanced risk of bone fragility. In this study, we aimed to identify novel genes for susceptibility to osteoporosis and/or bone density. Materials and Methods: To identify differentially expressed genes (DEGs) between control and osteoporosis-induced cells, annealing control primer-based differential display reverse-transcription polymerase chain reaction (RT-PCR) was carried out in pre-osteoblast MC3T3-E1 cells. Expression levels of the identified DEGs were evaluated by quantitative RT-PCR. Association studies for the quantitative bone density analysis and osteoporosis case-control analysis of single nucleotide polymorphism (SNPs) were performed in Korean women (3,570 subjects) from the Korean Association REsource (KARE) study cohort. Results: Comparison analysis of expression levels of the identified DEGs by quantitative RT-PCR found seven genes, Anxa6, Col5a1, Col6a2, Eno1, Myof, Nfib, and Scara5, that showed significantly different expression between the dexamethason-treated and untreated MC3T3-E1 cells and between the ovariectomized osteoporosis-induced mice and sham mice. Association studies revealed that there was a significant association between the SNPs in the five genes, ANXA6, COL5A1, ENO1, MYOF, and SCARA5, and bone density and/or osteoporosis. Conclusion: Using a whole-genome comparative expression analysis, gene expression evaluation analysis, and association analysis, we found five genes that were significantly associated with bone density and/or osteoporosis. Notably, the association P-values of the SNPs in the ANXA6 and COL5A1 genes were below the Bonferroni-corrected significance level.

• Design & Manufacturing
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• 제16권4호
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• pp.24-33
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• 2022

Fiber-reinforced plastics(FRPs) have excellent specific stiffness and strength, so they are usually used as automotive parts that require high rigidity and lightweight instead of metal. However, it is difficult to predict the mechanical properties of injection molded parts due to the fiber orientation and breakage of FRPs. In this paper, the fiber orientation characteristics and mechanical properties of injection molded specimens were evaluated in order to fabricate automotive transmission side covers with FRPs and design a rib structure for improvement of their rigidity. The test molds were designed and manufactured to confirm the fiber orientation characteristics of each position of the injection molded standard plate-shaped specimens, and the tensile properties of the specimens were evaluated according to the injection molding conditions and directions of specimens. A gusset-rib structure was designed to improve the additional structural rigidity of the target products, and a proper rib structure was selected through the flexural tests of the rib-structured specimens. Based on the evaluation of fiber orientation and mechanical characteristics, the optimization analyses of gate location were performed to minimize the warpage of target products. Also, the deformation analyses against the internal pressure of target product were performed to confirm the rigidity improvement by gusset-rib structure. As a result, it could be confirmed that the deformation was reduced by 27~37% compared to the previous model, when the gusset-rib structure was applied to the joining part of the target products.

• 멤브레인
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• 제32권6호
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• pp.496-513
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• 2022

본 연구에서는 음이온 교환막 수전해 시스템에 적용가능성을 확인하고자 상용 음이온 교환막인 FAA-3-50, Neosepta-ASE, Sustainion grade T, Fujifilm type 10의 관련 물성을 평가하였다. 음이온교환막을 이용하는 특성상 음이온교환기의 확인을 위하여 SEM/EDX를 이용하여 상용막의 모폴로지와 표면의 원소를 분석하여 상용막이 포함하고 있는 작용기의 분포를 확인하였다. 또한, UTM과 TGA를 이용하여 기계적 강도 및 열분해온도를 측정하여 수전해의 구동조건을 만족하는지 확인하였다. 음이온 교환막으로서의 성능을 파악하기 위하여 중요한 특성인 이온교환용량과 이온전도도를 측정하였으며, 알칼리 환경에서 구동되기 때문에 각각의 상용막의 내알칼리성을 확인하기 위한 내구성 테스트를 진행하여 비교하였다. 최종적으로 막-전극 접합체를 제조하여 수전해 single cell test를 진행하여 60℃, 70℃, 80℃의 온도 조건에서 cell 성능을 확인하였고 장기 cell test로 다른 온도에서 20 cycle 측정하여 수전해 성능을 비교하여 상용막의 음이온 교환막 수전해에 적용가능성을 비교하여 확인하였다.

• 한국지진공학회논문집
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• 제27권5호
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• pp.203-211
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• 2023

For fast-built and safe precast concrete (PC) construction, the dry mechanical splicing method is a critical technique that enables a self-sustaining system (SSS) during construction with no temporary support and minimizes onsite jobs. However, due to limited experimental evidence, traditional wet splicing methods are still dominantly adopted in the domestic precast industry. For PC beam-column connections, the current design code requires achieving emulative connection performances and corresponding structural integrity to be comparable with typical reinforced concrete (RC) systems with monolithic connections. To this end, this study conducted the standard material tests on mechanical splices to check their satisfactory performance as the Type 2 mechanical splice specified in the ACI 318 code. Two PC beam-column connection specimens with dry mechanical splices and an RC control specimen as the special moment frame were subsequently fabricated and tested under lateral reversed cyclic loadings. Test results showed that the seismic performances of all the PC specimens were fully comparable to the RC specimen in terms of strength, stiffness, energy dissipation, drift capacity, and failure mode, and their hysteresis responses showed a mitigated pinching effect compared to the control RC specimen. The seismic performances of the PC and RC specimens were evaluated quantitatively based on the ACI 374 report, and it appeared that all the test specimens fully satisfied the seismic performance criteria as a code-compliant special moment frame system.

• 대한의용생체공학회:의공학회지
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• 제44권4호
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• pp.284-292
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• 2023

This study attempted to observe muscle activity and muscle fatigue among isotonic exercise of Biceps Brachii and Deltoidus Medius, which correspond to upper limb muscles, using metronome. For the experiment, 13 adult men participated to evaluate biosignals (ECG, EMG). For quantitative evaluation, 1RM and MVIC test were carried out and a constant pace isotonic excise session was conducted. Five sets of exercise were performed, and each set proceeded to the failure point while the speed condition (30bpm) was assigned. As a result of the experiment, muscle activity in both muscles was significantly reduced in fifth set compared to first set. Muscle fatigue has been confirmed to occur at a significant level within the set, but there was only a significant difference in both muscles in the first and second sets between sets. This is similar to the results of previous studies that gives the same rest time(2min), but further research is needed to see if the conditions for the number of repetitions are affected. Based on the recent increase of interest in muscle strength exercise, this study was conducted to observe the results by varying the conditions of common exercise.

• 한국지진공학회논문집
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• 제27권3호
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• pp.147-155
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• 2023

This study aims to present a method to evaluate the relative risk of failure due to liquefaction of domestic small to medium-sized earthfill dams with a height of less than 15 m, which has little information on geotechnical properties. Based on the results of previous researches, a series of methods and procedures for estimating the probability of dam failure due to liquefaction, which calculates the probability of liquefaction occurrence of the dam body, the amount of settlement at the dam crest according to the estimation of the residual strength of the dam after liquefaction, the overtopping depth determined from the amount of settlement at the dam crest, and the probability of failure of the dam due to overtopping was explicitly presented. To this end, representative properties essential for estimating the probability of failure due to the liquefaction of small to medium-sized earthfill dams were presented. Since it is almost impossible to directly determine these representative properties for each of the target dams because it is almost impossible to obtain geotechnical property information, they were estimated and determined from the results of field and laboratory tests conducted on existing small to medium-sized earthfill dams in previous researches. The method and procedure presented in this study were applied to 12 earthfill dams on a trial basis, and the liquefaction failure probability was calculated. The analysis of the calculation results confirmed that the representative properties were reasonable and that the overall evaluation procedure and method were effective.