Objectives The purpose of this study was to review and evaluate the clinical evidence of the efficacy and safety of treatment based on Sasang constitutional medicine (SCM) for post-stroke patients by systematic review and meta-analysis. Methods Randomized controlled trials (RCTs), published in 10 electronic databases up to December 2020, were searched. For the included studies, Cochrane's risk of bias assessment was performed to analyze the methodological quality. The strength of evidence was evaluated using the grading of recommendations assessment, development, and evaluation system based on the results of analyses. All review processes were performed by two independent researchers. Results Five RCTs were finally included. All included RCTs were conducted for one month on post-stroke patients in 60-80s, four studies on Tae-Eum patients and one study on So-Yang patients. Four types of constitution-specific herbal medicine (Chungpyesagan-tang, Cheongsimsanyak-tang, Yeoldahanso-tang, and Yangkyuksanhwa-tang) and constitution-specific acupuncture therapy were identified as interventions. More than half of the included studies were evaluated as low quality due to the high-risk of bias in selection, performance, and detection. The combination of constitution-specific herbal medicine, acupuncture, and conventional treatment was more effective in improving the patients' motor impairment, dysphagia, aphasia, and depression than conventional treatment alone. No serious adverse events by SCM treatment were reported. Conclusions SCM treatment may improve the sequelae of post-stroke patients safely in combination with conventional treatment. Since the quality of clinical evidence included in this study was low, higher quality clinical evidence obtained in well-designed clinical studies will be needed.
International Journal of Computer Science & Network Security
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v.22
no.7
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pp.91-102
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2022
With the evolution of wireless sensor network (WSN) technology, the routing policy has foremost importance in the Internet of Things (IoT). A systematic routing policy is one of the primary mechanics to make certain the precise and robust transmission of wireless sensor networks in an energy-efficient manner. In an IoT environment, WSN is utilized for controlling services concerning data like, data gathering, sensing and transmission. With the advantages of IoT potentialities, the traditional routing in a WSN are augmented with decision-making in an energy efficient manner to concur finer optimization. In this paper, we study how to combine IoT-based deep learning classifier with routing called, Kriging Regressive Deep Belief Neural Learning (KR-DBNL) to propose an efficient data packet routing to cope with scalability issues and therefore ensure robust data packet transmission. The KR-DBNL method includes four layers, namely input layer, two hidden layers and one output layer for performing data transmission between source and destination sensor node. Initially, the KR-DBNL method acquires the patient data from different location. Followed by which, the input layer transmits sensor nodes to first hidden layer where analysis of energy consumption, bandwidth consumption and light intensity are made using kriging regression function to perform classification. According to classified results, sensor nodes are classified into higher performance and lower performance sensor nodes. The higher performance sensor nodes are then transmitted to second hidden layer. Here high performance sensor nodes neighbouring sensor with higher signal strength and frequency are selected and sent to the output layer where the actual data packet transmission is performed. Experimental evaluation is carried out on factors such as energy consumption, packet delivery ratio, packet loss rate and end-to-end delay with respect to number of patient data packets and sensor nodes.
Background: In physical activity or labor, the human body is in a state of high intensity stress, and all parts or physiological functions of the body respond positively to maintain or balance the need for movement. The human body has many physiological changes in the process of movement, and fatigue is the external manifestation of various complex changes inside the human body. Fatigue is also a physiological mechanism of self-protection after the body reaches a certain level of activity, which can prevent the occurrence of life-threatening excessive functional failure. The generation of fatigue is a very complex process, and its mechanism has not been concluded yet. Therefore, it is an important work to search and screen the effective components of natural plants that have anti-fatigue effect and to explore their mechanism. Methods: This was a 8-week, randomized, double-blind, placebo-controlled clinical trial. A total of 110 subjects who passed physical examination were included according to the scheme design, and randomly divided into a test group which was given KRG and a placebo control group. The calculation is carried out according to the standard of sub-high-intensity exercise test. Results: There was no adverse effect on safety index of subjects after taking red ginseng capsule. After KRG treatment, subjective strength grade is significant lower than placebo treatment. Blood lactic acid content is significantly get lower after trial in KRG group, and significant lower than placebo group. Creatine phosphokinase(CK) content is significantly get lower after trial in KRG group, and significant lower than placebo group. Conclusion: According to the criterion in the test scheme, the result shows that KRG is helpful on relieving physical fatigue.
Yang, Hee Chul;Chung, Seung Hyun;Yoo, Ji Sung;Park, Boram;Kim, Moon Soo;Lee, Jong Mog
Journal of Chest Surgery
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v.55
no.2
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pp.108-117
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2022
Background: The efficacy of telemedicine among cancer survivors is uncertain. The Smart After-Care Program (SAP), which is an interactive, smartphone-based remote health monitoring system, was developed to help patients manage their health after leaving the hospital. This study was designed to evaluate the efficacy of our remote health care program for lung cancer patients. Methods: We enrolled 50 patients with lung cancer. Self-monitoring devices were supplied to all patients, who were instructed to enter their daily vital signs and subjective symptoms to the Smart After-Care app. The app also provided information about rehabilitation exercises and a healthy diet for lung cancer patients. All patients received health counseling via telephone once a week and visited an outpatient clinic during weeks 6 and 12 to assess satisfaction with the SAP and changes in quality of life and physical performance. Results: Overall satisfaction with the SAP was very high (very good, 61.9%; good, 26.2%). In the multivariate analysis to identify factors affecting satisfaction, the distance between the patient's residence and the hospital was the only significant independent factor (p=0.013). Quality of life improved along all functional scales (p<0.05). Muscle strength significantly improved in the lower limbs (p=0.012). Two-minute walk distance also significantly improved (p=0.028). Conclusion: This study demonstrated that the SAP was acceptable for and supportive of patients with reduced pulmonary function after lung cancer treatment. The SAP was found to be particularly useful for patients living far from the hospital.
BACKGROUND/OBJECTIVES: Various sodium reduction policies have been implemented. However, there are limitations in the aspect of actual field applicability and efficiency. For effective sodium reduction, cooperation with the field is required and consumer preference must be considered. Thus, this study aimed to develop a low-sodium burger considering field applicability and consumer preference. MATERIALS/METHODS: Focus group interviews and in-depth interviews on the sodium reduction measures were conducted with nine professionals in related fields to discuss practical methods for sodium reduction from September 7 to 21, 2018. By reflecting the interview results, a burger using a low-sodium sauce was developed, and preference analysis for sodium in the burger sauces and finished products was performed. The consumer preference for low-sodium burgers was evaluated on 51 college students on November 12, 2018. RESULTS: The results of the professional interview showed that it is desirable to practice sodium reduction gradually, and by reflecting this, the burger sauce was prepared by adjusting the ratio of refined salt to 15%, 30%, and 50%. The sodium content of the burger using low-sodium sauce was 399 mg/100 g in the control group, 362 mg/100 g in the H1 group, and 351.5 mg/100 g in the H2 group, showing a 9.3-11.9% decrease in sodium in the H1 and H2 groups. The preference evaluation on the low-sodium burgers showed a higher preference for burgers with 9.3-11.9% sodium reduction, which did not affect the overall taste. CONCLUSIONS: This study examined the potential for sodium reduction in the franchise foodservice industry. An approximate 10% sodium reduction resulted in an increase in consumer preference without affecting the strength of the taste. Thus, if applied gradually, sodium reduction at practical levels could increase the consumer preference without changing the taste or quality and could be applied in the franchise foodservice industry.
Since the dredging reclaimed land consisting of soft ground is very weak in support, the difficult and complex factors should be considered in the design to calculate accurate bearing capacity of soft ground. Recently, various reinforcement construction methods of soft ground have been designed for dredged landfills, but the stabilities are predicted by calculating conventional Meyerhof (1974) equation for trafficability in soft ground. Conventional equations increase economic costs by underestimating bearing capacity of weak ground in order to ensure constructive safety, so a modified equation has been proposed from the literature. The paper attempts to experiment and compute important factors, such as stitching fiber and seam tensile strength of geotextiles, that are not theoretically considered and can be identified in the field. In addition, The evaluation of the bearing capacity of the modified equation is verified to be stable for trafficability through the plate bearing test performed on site.
Due to the scarcity of extortionate experimental data, fatigue failure of the reinforced concrete (RC) element might be achieved economically adopting nonlinear finite element (FE) analysis as an alternative approach. However, conventional implicit dynamic analysis is expensive, quasi-static method overlooks interaction effects and inertia, direct cyclic analysis computes stabilized responses. Apart from this, explicit dynamic analysis may provide a numerical operating system for factual long-term responses. The study explores the fatigue behavior based on a simplified explicit dynamic solution employing nonlinear time domain analysis. Among fourteen RC beams, one beam is selected to validate under static loading, one under fatigue with the experimental study and other twelve to check the detail fatigue behavior. The SWOT (Strength, Weakness, Opportunities, Threats) analysis has been carried out to pinpoint the detail scenario in the adoption of numerical approach as an alternative to the experimental study. Excellent agreement of FE and experimental results is seen. The 3D nonlinear RC beam model at service fatigue limits is truthful to be used as an expedient contrivance to envisage the precise fatigue behavior. The simplified analysis approach for RC beam under fatigue offers savings in computation to predict responses providing acceptable accuracy rather than the complicated laboratory investigation. At higher frequency, the flexural failure occurs a bit earlier gradually compared to the repeated loading case of lower frequency. The deflection increases by 6%-10% at the end of first cycle for beams with increasing frequency of cyclic loading. However, at the end of fatigue loading, greater deflection occur earlier for higher load range because of more rapid stiffness degradation. For higher frequency, a slight boost in concrete compressive strains at an initial stage of loading has been seen indicating somewhat stepper increment. Stiffness degradation in larger loading cycle at same duration escalates the upsurge of the rate of strain in case of higher frequency.
Journal of the Korean Recycled Construction Resources Institute
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v.10
no.4
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pp.420-427
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2022
The present study evaluated the physical, mechanical and thermal properties of the foam glass aggregate and insulation foundation with this, in order to promote the use of insulated foundations using domestically produced foamed glass aggregates. As a result of the evaluation, the compacted foam glass aggregate showed at the same level as overseas products in terms of unit volume mass, particle size and other characteristics, and a compressive strength of 40.6 N/cm2, which was superior to the existing organic insulation materials such as XPS. And the thermal conductivity of the foam glass aggregate was 0.84 W/mK, and the thermal transmittance of the specimen simulating the insulation foundation was 0.37 W/mK, so the thermal conductivity of the foam glass aggregate was estimated to be 0.80 W/mK. With these results, it was found that it is possible to use the insulation foundation with re-producted foam glass aggregate by crushing the waste from the process of producing foam glass products.
Chae-Ik, Lim;Se-Ho, Park;Won-Woo, Kim;Jae-Heum, Moon;Seung-Tae, Lee
Journal of the Korean Recycled Construction Resources Institute
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v.10
no.4
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pp.489-497
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2022
In this study, the fluidity, mechanical properties and microstructure of cement pastes with carbon nanotube (CNT) were experimentally investigated. The 6 types of cement paste mixes with different PCE:CNT and w/b had been manufactured, and several tests including flow, compressive strength, absorption and water porosity were performed on cement pastes with or without CNT.Additionally, microstructural observations such as x-ray diffraction (XRD) and scanning electron microscopy (SEM) were carried out to examine hydrates formed in cement paste with CNT. As a result, it was found that the performance of cement pastes with CNT was better compared to that of control cement paste (OPC) due to both of hydration acceleration effect and filling effect. Furthermore, the SEM images clearly showed that CNT can bridge cracks formed in cement matrix. Conclusively, it is believed that the CNT, if mixed appropriately, could be an option as nono-materials to improve performance of concrete structures.
To obtain the dynamic mechanical properties, fracture modes, energy and brittleness characteristics of Furong Baijiao coal rock, the dynamic impact compression tests under 0, 4, 8 and 12 MPa confining pressure were carried out using the split Hopkinson pressure bar. The results show that failure mode of coal rock in uniaxial state is axial splitting failure, while it is mainly compression-shear failure with tensile failure in triaxial state. With strain rate and confining pressure increasing, compressive strength and peak strain increase, average fragmentation increases and fractal dimension decreases. Based on energy dissipation theory, the dissipated energy density of coal rock increases gradually with growing confining pressure, but it has little correlation with strain rate. Considering progressive destruction process of coal rock, damage variable was defined as the ratio of dissipated energy density to total absorbed energy density. The maximum damage rate was obtained by deriving damage variable to reflect its maximum failure severity, then a brittleness index BD was established based on the maximum damage rate. BD value declined gradually as confining pressure and strain rate increase, indicating the decrease of brittleness and destruction degree. When confining pressure rises to 12 MPa, brittleness index and average fragmentation gradually stabilize, which shows confining pressure growing cannot cause continuous damage. Finally, integrating dynamic deformation and destruction process of coal rock and according to its final failure characteristics under different confining pressures, BD value is used to classify the brittleness into four grades.
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