• Journal of Gastric Cancer
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• v.20 no.4
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• pp.385-394
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• 2020

Purpose: Patients with gastric cancer who receive neoadjuvant therapy are staged before treatment (cStage) and after treatment (ypStage). We aimed to compare the prognostic reliability of cStage and ypStage, alone and in combination. Materials and Methods: Data for all patients who received neoadjuvant therapy followed by surgery for gastric adenocarcinoma from 2004 to 2015 were extracted from the National Cancer Database. Kaplan-Meier (KM)curves were used to model overall survival based on cStage alone, ypStage alone, cStage stratified by ypStage, and ypStage stratified by cStage. P-values were generated to summarize the differences in KM curves. The discriminatory power of survival prediction was examined using Harrell's C-statistics. Results: We included 8,977 patients in the analysis. As expected, increasing cStage and ypStage were associated with worse survival. The discriminatory prognostic power provided by cStage was poor (C-statistic 0.548), while that provided by ypStage was moderate (C-statistic 0.634). Within each cStage, the addition of ypStage information significantly altered the prognosis (P<0.0001 within cStages I-IV). However, for each ypStage, the addition of cStage information generally did not alter the prognosis (P=0.2874, 0.027, 0.061, 0.049, and 0.007 within ypStages 0-IV, respectively). The discriminatory prognostic power provided by the combination of cStage and ypStage was similar to that of ypStage alone (C-statistic 0.636 vs. 0.634). Conclusions: The cStage is unreliable for prognosis, and ypStage is moderately reliable. Combining cStage and ypStage does not improve the discriminatory prognostic power provided by ypStage alone. A ypStage-based prognosis is minimally affected by the initial cStage.

• The Journal of Fisheries Business Administration
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• v.51 no.2
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• pp.1-13
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• 2020

The purpose of this study is to analyze consumer preference for fish farm HACCP certification using conjoint analysis. This study used raw flatfish product to evaluate the fish farm HACCP. In this study, 500 consumers were surveyed using panel survey and stratified sampling. In the recognition analysis, the farm HACCP certification system was found to be highly recognized by consumers. It can be seen that the brand assets accumulated by existing food and agricultural HACCP certification were transfered to the fish farm HACCP and absorbed. Consumers perceived fish farm HACCP certification as similar one with existing food and agricultural HACCP. Conjoint analysis evaluated three levels factors. The attributes and levels evaluated were : price(25,800 won, 28,400 won, 31,000 won), certification(fish farm HACCP, seafood traceability, and non certified), and origin(domestic, JEJU, and WANDO). The important levels were in order of price(40.8%), certification(30.2%) and origin(29.0%). We found that consumers give higher utility to fish farm HACCP certification compared with non certified and seafood traceability certification. Market simulation results showed that the fish farm HACCP product has 12%p higher market share than non certified products. Seafood traceability certification showed 4.6%p higher market share than non certified products.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.2033-2036
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• 2013

Many studies have suggested that the XRCC1 Arg280His gene polymorphism might be involved in the development of hepatocellular carcinoma (HCC). However, the results have been inconsistent. In this study, the authors performed a meta-analysis to assess the association between XRCC1 Arg280His and HCC susceptibility. Published literature from PubMed, EMBASE and CNKI Data was searched. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using fixed- or random-effects models when appropriate. Begg's test was used to measure publication bias. A total of 7 case-control studies covering 1,448 HCC cases and 1,544 controls were included. No significant variation in HCC risk was detected in any of the genetic models overall. In the stratified analysis, four studies with sample sizes over 300 produced similar results. The corresponding pooled ORs were not substantially altered after the exclusion of three studies deviating from Hardy-Weinberg equilibrium in the control group, which indicated reliability for our meta-analysis results.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3483-3488
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• 2012

Objective: Several studies have demonstrated associations between the TERT rs2736098 single nucleotide polymorphisms (SNPs) and susceptibility to cancer development. However, there are conflicting results. A systematic meta-analysis was therefore performed to establish the cancer risk associated with the polymorphism. Methods: In this meta-analysis, a total of 6 case-control studies, including 5,567 cases and 6,191 controls, were included. Crude odds ratios with 95% confidence intervals were used to assess the strength of associations in several genetic models. Results: Our results showed no association reaching the level of statistical significance for overall risk. Interestingly, in the stratified analyses (subdivided by ethnicity), significantly increased risks were found in the Asian subgroup which indicates the TERT rs2736098 polymorphism may have controversial involvement in cancer susceptibility. Conclusions: Overall, this meta-analysis indicates that the TERT rs2736098 polymorphism may have little involvement in cancer susceptibility.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.3169-3173
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• 2013

Background: Findings from previous published studies regarding the association of the XRCC3 Thr241Met polymorphism with glioma susceptibility have often been conflicting. Therefore, a meta-analysis including all available publications was carried out to make a more precise estimation of the potential relationship. Methods: By searching the electronic databases of Pubmed and Embase (up to April 1st, 2013), a total of nine case-control studies with 3,752 cases and 4,849 controls could be identified for inclusion in the current meta-analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess the strength of the association. Results: This meta-analysis showed the XRCC3 Thr241Met polymorphism to be significantly associated with decreased glioma risk in the allelic model (Met allele vs. Thr allele: OR= 0.708, 95%CI= 0.631-0.795). Moreover, we also observed a statistically significant association between the XRCC3 Thr241Met polymorphism and reduced glioma risk in analyses stratified by ethnicity (Asian) and source of controls (hospital based) in the allelic model. Conclusions: Current evidence suggests that the XRCC3 Thr241Met polymorphism may be a risk factor for glioma development, especially in Asians.

• Journal of the Korean Society of Clothing and Textiles
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• v.17 no.2
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• pp.281-289
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• 1993

Concept of the comfort and fitness becomes a major concern in the basic function of the ready-made clothes. Accordingly a more sophiscated classification of the human morphological characteristics is strongly required for the effective clothing construction. This research was performed to classify and characterize Korean adult males anthropometrically. Sample size was 1290 subjects and their age range was from 19 to 54 years old. Sampling was carried out by the stratified sampling method. Data were collected by the direct anthropometric measurement. 75 variables in total were applied to classify the bodytypes. Data were analyzed by the multivariate method, especially factor and cluster analysis. The high factor loading items extracted by factor analysis were based to determine the variables of the cluster analysis for the similar bodytypes respectively. In the part of the trunk, 19 variables from the data were applied to classify the bodytypes of trunk by Ward's minimum variance method. The groups forming a cluster were subdivided into 5 sets by cross-tabulation extracted by the hierarchical culster analysis. Type 3 and 4 in trunk were composed of the majority of 55.6% of the subjects. The Korean adult males had relatively well-balanced bodytypes in trunk.

• Journal of Mechanical Science and Technology
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• v.17 no.9
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• pp.1380-1387
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• 2003

When a cold HPSI (High pressure Safety Injection) fluid associated with an overcooling transient, such as SGTR (Steam Generator Tube Rupture), MSLB (Main Steam Line Break) etc., enters the cold legs of a stagnated primary coolant loop, thermal stratification phenomena will arise due to incomplete mixing. If the stratified flow enters the downcomer of the reactor pressure vessel, severe thermal stresses are created in a radiation embrittled vessel wall by local overcooling. As general thermal-hydraulic system analysis codes cannot properly predict the thermal stratification phenomena, RG 1.154 requires that a detailed thermal-mixing analysis of PTS (pressurized Thermal Shock) evaluation be performed. Also. previous PTS studies have assumed that the thermal stratification phenomena generated in the stagnated loop side of a partially stagnated primary coolant loop are neutralized in the vessel downcomer by the strong flow from the unstagnated loop. On the basis of these reasons, this paper focuses on the development of a 3-dimensional thermal-mixing analysis model using PHOENICS code which can be applied to both partial and total loop stagnated cases. In addition, this paper verifies the fact that, for partial loop stagnated cases, the cold plume generated in the vessel downcomer due to the thermal stratification phenomena of the stagnated loop is almost neutralized by the strong flow of the unstagnated loop but is not fully eliminated.

• Journal of the Korean Society of Clothing and Textiles
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• v.16 no.4 s.44
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• pp.393-403
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• 1992

This Study intended to provide positioning strategies of brand Image for ladies' ready to wear by analysing the perceptual dimensions of working women. The subjects were devided into two groups according to the fashion involvement, and in each group, a positioning map was composed by use of multidimensional scaling. 251 subjects of this study were gathered into stratified sample groups from working women in Seoul, being subdivided according to their each occupation and age. The data were analysed by frequency, percentage, average, $x^{2}-test$, 1-test, Factor Analysis, cronbach's $\alpha$. Also, KYST, PROFIT, PREFMAP for multidimensional scaling were used. The results were as follows. 1. Two groups were identified according to degree of fashion involvement: high-involvement group, and low-involvement group. 2. From the analysis of the similarity of brand image, high involvement group percieved greater difference in brand image than low involvement group. 3. From the analysis of the evaluation of brand attributes, the evaluations in self expression, fashionability, design, sales promotion activity, sociality, quality, fit showed differences bet-ween high involvement group and low involvement group. 4. From the analysis of the preference of brand image, the distribution of preference and ideal point were different between high involvement group and low involvement group.

• Journal of Digital Convergence
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• v.15 no.11
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• pp.567-579
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• 2017

The purpose of this study was conducted to clarify physical activity university students on time perspective in leisure constraints and leisure flow. To achieve this purpose, subjects of this study were sampled 295 Physical Activity University Students participant using purposeful sampling method for 2 months from May to June of 2017. Using questionnaires stratified cluster random sampling in university students in D city and C city. The analysis method was used t-test, one-way ANOVA, multiple regression analysis, correlation analysis methods in order to solve problems of the study. According to the study Result, First, studies show that female have high levels of leisure constraints than males. Males have higher levels of leisure flow than females. The first grader show high level of individual constraints and past negation were also high. In the series of majors, natural affiliates and humanities are high in the past negation, present destiny, the service major currently high in pleasure and of leisure, autotelic experience of leisure flow. In the rhythmic type of Activity type, the past negation, present destiny and leisure constraints are highly likely to be higher. In the competitive have shown that is high. Second, leisure constraints on students' participation in physical activities have been found to have negative influence on their students. Third, leisure flow have shown that they have a positive effect on past affirmation and present pleasure.

• Korean Journal of Environmental Biology
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• v.30 no.3
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• pp.219-230
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• 2012

We surveyed 23 sites of Jinhae Bay in spring and summer 2010 in order to study the correlation between the variation of environmental factors, including salinity, temperature, and nutrients and the characteristics of phytoplankton community structures in summer stratification. Phytoplankton biomass was high in the surface water in summer; however, it was very low in the bottom water. The results showed a negative correlation between chlorophyll a (chl. a) and nutrients (silicate, nitrate, nitrite, ammonium, and phosphate) or nutrients ratio in summer; however, there was mostly a positive correlation between chl. a and these nutrients in spring. This inconsistent correlation between spring and summer was attributed to the phytoplankton community, because a diverse phytoplankton community has different nutrient uptake abilities. In addition, the results of CCA (canonical correspondence analysis) showed a negative correlation between phosphate and dominant species, including Chaetoceros spp., Skeletonema costatum-like spp., and Pseudo-nitzschia delicatissima in summer, but a strong positive correlation between DIN (dissolved inorganic nitrogen) and the dominant species, including Cryptomonas spp. and Pseudo-nitzschia multistriata in spring. Consistently, the dominant algal species in summer showed a relatively smaller size cells compared with those in spring, suggested that it may have related with the low nutrient levels at surface layer due to strong stratified water column of summer.