• 보건행정학회지
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• 제24권4호
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• pp.389-395
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• 2014

Background: Family planning is widely practiced today to resolve the over-growing population and overcome obstacles that thwart socio-economic growth. While Ghana was the first country in Africa to implement family planning program, its birthrate is still twice as much as world average due to weak infrastructure and strategic plans to enforce the policy. Thus, there is a need to objectively verify the factors that affect family planning of fertile women of Ghana. Methods: Total of 630 self-administered questionnaires were distributed from April 8 to 17 of 2013 to collect data. Six-hundred eighteen questionnaires were analyzed, excluding the 12 incomplete questionnaires. Collected data were analyzed using PASW SPSS ver. 18, and logistic regression analysis was performed to verify the factors that affect practice of family planning. Results: Satisfaction with health and medical facilities, experience with family planning education and awareness of birth control methods significantly affected practice of family planning. Based on analysis using odds ratio, enforcement rate of family planning increased by 4.574 times when the subjects were satisfied with health and medical facilities, by 3.920 times when received family planning education, and by 3.284 times when they were aware of birth control methods. Conclusion: By adopting family planning education program, government should be able to change fertile women's perception of family planning. A strategic plan is necessary in order to increase access to medical facilities, improve service satisfaction, and induce women to enforce family planning voluntarily.

• 기술혁신연구
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• 제24권2호
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• pp.143-175
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• 2016

본 연구는 기업 혁신 산업 특성이 기업의 전유전략에 미치는 영향을 특허와 영업비밀의 상대적 선호를 중심을 '한국기업혁신조사' 2005, 2010, 2014년 자료를 통해 분석하였다. 분석결과 벤처기업, 고기술산업에 속한 기업, 정부의 연구개발 자금지원을 받은 기업, 제품혁신 수행기업과 연구개발 지출이 높은 기업에서 특허를 영업비밀보다 상대적으로 선호하는 것으로 나타났다. 그러나 기업규모와 연구개발 협력여부는 통계적으로 유의한 영향을 미치지 않았다. 이는 산업별 특성을 고려한 전유제도 정책이 보다 효과적일 수 있다는 것을 보여준다. 높은 시장집중도를 가진 산업에 속한 기업들은 영업비밀을 선호하는 것으로 나타났으며, 이러한 특성은 소기업과 벤처기업에서 명확히 나타났다. 이는 선도기업의 전략적 특허출원의 증가가 소기업과 벤처기업의 특허활동을 제약할 수 있다는 것을 의미한다. 과도한 전략적 특허의 증가는 궁극적으로 소규모 기업들의 기술활동을 저해할 가능성이 있기 때문에 불필요한 전략적 특허의 남용을 방지할 수 있는 정책적 노력이 필요할 것이다.

• 대한한의학회지
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• 제37권3호
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• pp.97-111
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• 2016

Objectives: This study aims to investigate the policy status of traditional medicine standardization between Korea and China as well as to derive a strategic development plan for Korean medicine standardization. Methods: The existing national plans and preceding studies on traditional medicine standardization in Korea and China were reviewed, and scope of the study was categorized as having three main aspects: infrastructure; standard development and standardization activities; and application and diffusion. Results: Nine development plans for Korean medicine standardization derived under the study were as follows: With regard to infrastructure of standardization, 1) standardization plan of Korean medicine shall be established based on involvement of multi-government ministries. 2) It shall be set with a consistent cooperation process among standardization-related organizations, as well as 3) encourage the industry to participate in standardization activities. To activate standards development, 4) launching the R&D-standardization-industrialization linked project, 5) supporting Korean medicine society and the mirror committee for motivation, and 6) planning the international joint research for development of standard and expanding standardization activities are recommended. In the aspect of application, there is a need for 7) expanding certification systems for the industry and 8) evaluation and feedback on the life-cycle of standardization. Lastly, 9) educational programs for training experts of standardization shall be developed and implemented. Conclusions: In order to invigorate standardization activities for Korean medicine, enhancement of planning and evaluation capacity, ensuring the strategic development of standards, broadening boundaries of international standardization activities, and training professionals are required.

• 품질경영학회지
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• 제44권2호
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• pp.389-408
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• 2016

Purpose: This study was designed to analyze the behavioral change of knowledge structures and the trends of research topics in the quality management field. Methods: The network structure and knowledge structure of the words were visualized in map form using co-word analysis, cluster analysis and strategic diagram. Results: Summarizing the research results obtained in this study are as follows. First, the word network derived from co-occurrence matrix had 106 nodes and 5,314 links and its density was analyzed to 0.95. Average betweenness centrality of word network was 2.37. In addition, average closeness centrality and average eigenvector centrality of word network were 0.01. Second, by applying optimal criteria of cluster decision and K-means algorithm to word co-occurrence matrix, 106 words were grouped into seven clusters such as standard & efficiency, product design, reliability, control chart, quality model, 6 sigma, and service quality. Conclusion: According to the results of strategic diagram analysis over time, the traditional research topics of quality management field related to reliability, 6 sigma, control chart topics in the third quadrant were revealed to be declined for their study importance. Research topics related to product design and customer satisfaction were found to be an important research topic over analysis periods. Research topic related to management innovation was emerging state and the scope of research topics related to process model was extended to research topics with system performance. Research topic related to service quality located in the first quadrant was analyzed as the key research topic.

• 디지털융복합연구
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• 제16권2호
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• pp.27-36
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• 2018

재무적 IT 투자 효과 측정 방법들은 기업의 요구를 충족시킬 수 없었다. 그러므로, IT 투자에 대한 종합적이고 비 재무적 성과측정 모형에 대한 많은 요구가 있었다. 본 연구에서는, 이러한 요구에 부응하기 위해 기업의 업무 프로세스에 기반 한 IT 성과측정 모형을 제시하고 있다. 본 연구에서 제시된 모형은 기업의 IT목표와 전략적 조정을 측정변수로 사용하여 기업의 성과측정 모형을 제시한다. 국내 125개 기업을 IT에 대한 목표에 따라 다음과 같이 네 개의 그룹으로 분류하여 데이터를 수집하였다: "무 중심", "운영 중심", "시장 중심", "이중 중심". 분석결과를 통해서 우리는 IT에 대한 더 높은 집중(중심)을 갖고 있는 기업일수록 보다 더 높은 IT 투자 성과를 인지하고, 또한 이는 IT에 대한 기업 목표의 정도가 IT 투자의 성과를 측정하기 위한 척도가 된다는 것을 알 수 있었다.

• Nutrition Research and Practice
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• 제15권5호
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• pp.579-590
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• 2021

BACKGROUND/OBJECTIVES: Petasites japonicus Maxim (P. japonicus) has been used as an edible and medicinal plant and contains many bioactive compounds. The purpose of this study is to investigate the effect of P. japonicus on osteogenesis. MATERIALS/METHODS: The leaves and stems of P. japonicus were separated and extracted with hot water or ethanol, respectively. The total phenolic compound and total polyphenol contents of each extract were measured, and alkaline phosphatase (ALP) activity of each extract was evaluated to determine their effect on bone metabolism. To investigate the effect on osteoblast differentiation of the aqueous extract of P. japonicus leaves (AL), which produced the highest ALP activity among the tested extracts, collagen content was measured using the Sirius Red staining method, mineralization using the Alizarin Red S staining method, and osteocalcin production through enzyme-linked immunosorbent assay analysis. Also, real-time reverse transcription polymerase chain reaction was performed to investigate the mRNA expression levels of Runt-related transcriptional factor 2 (Runx2) and Osterix. RESULTS: Among the 4 P. japonicus extracts, AL had the highest values in all of the following measures: total phenolic compounds, total polyphenols, and ALP activity, which is a major biomarker of osteoblast differentiation. The AL-treated MC3T3-E1 cells showed significant increases in induced osteoblast differentiation, collagen synthesis, mineralization, and osteocalcin production. In addition, mRNA expressions of Runx2 and Osterix, transcription factors that regulate osteoblast differentiation, were significantly increased. CONCLUSIONS: These results suggest that AL can regulate osteoblasts differentiation, at least in part through Runx2 and Osterix. Therefore, it is highly likely that P. japonicus will be useful as an alternate therapeutic for the prevention and treatment of osteoporosis.

• Nutrition Research and Practice
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• 제17권2호
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• pp.206-217
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• 2023

BACKGROUND/OBJECTIVES: The immunomodulatory effect of Platycodon grandiflorum (PG) has been reported, but studies on its mechanism are still lacking. This study was undertaken to confirm whether the hydrolyzed and fermented PG extract (HFPGE) obtained by adding hydrolysis and fermentation to the extraction process has an immune-enhancing effect in the in vivo system. MATERIALS/METHODS: Five-week-old BALB/c mice were divided into 4 groups: normal control group (NOR), control group (CON), 150 mg/kg body weight (BW)/day HFPGE-treated group (T150), and 300 mg/kg BW/day HFPGE-treated group (T300). The mice were administered HFPGE for 4 weeks and intraperitoneally injected with cyclophosphamide (CPA, 80 mg/kg BW/day) on day 6, 7, and 8, respectively, to induce immunosuppression. The levels of immunoglobulins (Igs) and cytokines were measured in the serum. In splenocytes, proliferation and cytokine levels were measured. RESULTS: Serum IgA, IgG, and IgM levels were observed to decrease after CPA treatment, which was recovered by HFPGE administration. The levels of serum interleukin (IL)-12, tumor necrosis factor (TNF)-α, IL-8, and transforming growth factor (TGF)-β were also decreased after exposure to CPA but increased after HFPGE administration. Decreased splenocyte proliferation was seen in CPA-treated mice, but was observed to increase in the T150 and T300 groups as compared to the NOR group. Compared to the CON group, splenocyte proliferation stimulated with concanavalin A (ConA) or lipopolysaccharide (LPS) in the HFPGE-treated groups was significantly increased. The cytokines secreted by ConA-stimulated splenocytes (IL-2, IL-12, interferon-γ, TNF-α) were increased in the T150 and T300 groups, and cytokines secreted by LPS-stimulated splenocytes (IL-4, IL-8, TGF-β) were also increased by HFPGE administration. CONCLUSION: These results suggest that HFPGE stimulates the immunity in immunosuppressed conditions, thereby enhancing the immune response. Therefore, it is expected that HFPGE has the potential to be used as functional food and medicine for immune recovery in various immunocompromised situations.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2003년도 추계학술대회 논문집
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• pp.1231-1232
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• 2003

This paper reports results of a recent survey of 184 Information Technology(IT) development practitioners and 90 User Interface (UI)/usability practitioners. This survey covered a broad range of issues including the respondents' profile, current development environment, usability and user-centered design (UCD) adoption issues in development, overall assessment of usability/UCD in Korea, and the most widely used methods and techniques. The results of this study are expected to provide an empirical basis for usability and UCD planning, training, adoption and execution in IT industry of Korea.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 하계학술대회 논문집 A
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• pp.572-574
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• 2003

The congestion management is a key task for enhancing the effectiveness of transmission pricing mechanism in a competitive electricity market. In this paper, the zonal method of congestion management is analyzed quantitatively using equilibrium concept, and compared with the nodal pricing method. It is shown that the generation firm uses different strategies in the two methods, and the overall performance of zonal congestion management depends on the determination of zones.

• 한국경영과학회지
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• 제34권3호
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• pp.29-41
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• 2009

The purpose of this paper is to develop a new classification method for predicting consumer choice based on genetic algorithm, and to validate Its prediction power over existing methods. To serve this purpose, we propose a hybrid model, and discuss Its methodological characteristics in comparison with other existing classification methods. Also, we conduct a series of experiments employing survey data of consumer choices of MP3 players to assess the prediction power of the model. The results show that the suggested model in this paper is statistically superior to the existing methods such as logistic regression model, artificial neural network model and decision tree model in terms of prediction accuracy. The model is also shown to have an advantage of providing several strategic information of practical use for consumer choice.