• 제목/요약/키워드: Stimulus

검색결과 1,744건 처리시간 0.028초

전정기 기능 향상을 위한 회전과 구르기 훈련 프로그램의 개발 및 검증 (Development and Verification of Treatment Programs by Turn and Roll Types to Improve the Function of Vestibular System)

  • 박양선;강성호;임영태
    • 한국운동역학회지
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    • 제22권2호
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    • pp.209-217
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    • 2012
  • The purpose of this study was to develop a turn-type treatment program which applies the principle of spotting and a roll-type treatment program that induces off-vertical axis. 29 collegiate students volunteered for this study. 12-week treatment programs were applied to both 15 students for turn-type treatment group and 14 students for roll-type treatment group. As an analytic tool, eye camera was employed to verify the treatment programs for a stimulus upon a turn, recovery after a stimulus upon a turn, and nystagmus that affects a vestibular system. Two-way ANOVA with repeated measures was applied to see the significant differences between the treatment groups, and between the test periods. For Post-Hoc Test, paired t-test was used to within the group and independent t-test was used to between the groups. The results indicated that roll-type treatment training has maximized a stimulus on nystagmyus during the stimulus by a roll. Turn-type treatment training has maximized a stimulus on nystagmyus right after a stimulus by a roll and significantly decreased the intensity of nystagmyus during the recovery. Both turn and roll type treatments have reduced the recovery time which from nystagmyus to a normal status. Roll-type treatment has showed a much shorter recovery time for nystagmyus than the roll-type treatment has. Based on the results of treatment programs developed in this study, we expect the treatment programs can be applied to treat dizziness and to improve the function of vestibular system as a rehabilitation tool.

Hyperosmotic Stimulus Down-regulates $1{\alpha}$, 25-dihydroxyvitamin $D_3$-induced Osteoclastogenesis by Suppressing the RANKL Expression in a Co-culture System

  • Tian, Yu-Shun;Jeong, Hyun-Joo;Lee, Sang-Do;Kong, Seok-Heui;Ohk, Seung-Ho;Yoo, Yun-Jung;Seo, Jeong-Taeg;Shin, Dong-Min;Sohn, Byung-Wha;Lee, Syng-Ill
    • The Korean Journal of Physiology and Pharmacology
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    • 제14권3호
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    • pp.169-176
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    • 2010
  • The hyperosmotic stimulus is regarded as a mechanical factor for bone remodeling. However, whether the hyperosmotic stimulus affects $1{\alpha}$, 25-dihydroxyvitamin $D_3$ ($1{\alpha},25(OH)_2D_3$)-induced osteoclastogenesis is not clear. In the present study, the effect of the hyperosmotic stimulus on $1{\alpha},25(OH)_2D_3$-induced osteoclastogenesis was investigated in an osteoblast-preosteoclast co-culture system. Serial doses of sucrose were applied as a mechanical force. These hyperosmotic stimuli significantly evoked a reduced number of $1{\alpha},25(OH)_2D_3$-induced tartrate-resistant acid phosphatase-positive multinucleated cells and $1{\alpha},25(OH)_2D_3$-induced bone-resorbing pit area in a co-culture system. In osteoblastic cells, receptor activator of nuclear factor ${\kappa}B$ ligand (RANKL) and Runx2 expressions were down-regulated in response to $1{\alpha},25(OH)_2D_3$. Knockdown of Runx2 inhibited $1{\alpha},25(OH)_2D_3$-induced RANKL expression in osteoblastic cells. Finally, the hyperosmotic stimulus induced the overexpression of TonEBP in osteoblastic cells. These results suggest that hyperosmolarity leads to the down-regulation of $1{\alpha},25(OH)_2D_3$-induced osteoclastogenesis, suppressing Runx2 and RANKL expression due to the TonEBP overexpression in osteoblastic cells.

뇌의 좌반구와 우반구의 작용에 미치는 음의 서로 다른 영향 (Different Effects of Sound Stimuli on Performing Left-and Right-Hemispheric Tasks)

  • 강성훈;安藤四一;차일환
    • 한국음향학회지
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    • 제6권2호
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    • pp.5-14
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    • 1987
  • 소음과 음악이 정신작업에 어떠한 영향을 미치는가를 검토하기 위해, 국민학생을 대상으로 소음그룹과 음악그룹으로 나누어 좌반구작업으로서 수의 가산데스트를, 우반구작업으로서 그림의 패턴찾기 테스트를 실시하였다. 그 결과소음과 음악의 작업에 미치는 영향은 매우 달랐다. 음악그룹의 피험자가 가산작업을 한 경우의 작업량은 평균 작업량보다 다 적은 주기를 나타내는 경향이 있다. 이것은 좌반구에서 가제작업과 음악처리간의 간섭때문이다. 한편, 소음하에서의 의 가산작업은 소음과 가산작업이 좌우 다른 반구에서 처리되므로 소음의 영향은 나타나지 않았다. 소음하의 패턴 찾기 테스트에서는 피험자가 작업중에 동요를 나타내는 경향을 보였다. 의미없는 소음은 우반구에서 처리되기 때문에 이것은 우반구에서의 간섭효과로 실명할 수 있다.

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완전삽입형 인공망막 구현을 위한 인공망막모듈 개발 (Development of Retinal Prosthesis Module for Fully Implantable Retinal Prosthesis)

  • 이강욱;카이호 요시유키;후쿠시마 타카후미;타나까 테츠;고야나기 미쯔마사
    • 대한의용생체공학회:의공학회지
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    • 제31권4호
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    • pp.292-301
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    • 2010
  • To restore visual sensation of blind patients, we have proposed a fully implantable retinal prosthesis comprising an three dimensionally (3D) stacked retinal chip for transforming optical signal to electrical signal, a flexible cable with stimulus electrode array for stimulating retina cells, and coupling coils for power transmission. The 3D stacked retinal chip is consisted of several LSI chips such as photodetector, signal processing circuit, and stimulus current generator. They are vertically stacked and electrically connected using 3D integration technology. Our retinal prosthesis has a small size and lightweight with high resolution, therefore it could increase the patients` quality of life (QOL). For realizing the fully implantable retinal prosthesis, we developed a retinal prosthesis module comprising a retinal prosthesis chip and a flexible cable with stimulus electrode array for generating optimal stimulus current. In this study, we used a 2D retinal chip as a prototype retinal prosthesis chip. We fabricated the polymide-based flexible cable of $20{\mu}m$ thickness where 16 channels Pt stimulus electrode array was formed in the cable. Pt electrode has an impedance of $9.9k{\Omega}$ at 400Hz frequency. The retinal prosthesis chip was mounted on the flexible cable by an epoxy and electrically connected by Au wire. The retinal prosthesis chip was cappted by a silicone to pretect from corrosive environments in an eyeball. Then, the fabricated retinal prosthesis module was implanted into an eyeball of a rabbit. We successfully recorded electrically evoked potential (EEP) elicited from the rabbit brain by the current stimulation supplied from the implanted retinal prosthesis module. EEP amplitude was increased linearly with illumination intensity and irradiation time of incident light. The retinal prosthesis chip was well functioned after implanting into the eyeball of the rabbit.

운전자 정보전달을 위한 차량용 햅틱시트 연구 (Study on Vehicle Haptic-Seat for the Information Transfer to Driver)

  • 오승용;김경태;유창호;한갑수;권대규
    • 재활복지공학회논문지
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    • 제8권1호
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    • pp.1-7
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    • 2014
  • 본 연구에서는 기존의 시/청각 방식의 운전정보 전달체계의 한계를 극복하고 더불어 교통약자들의 운전 수행에 도움이 되는 자동차용 햅틱시트 기술을 개발하고자 하였다. 이를 위해 동전형 모터 30개를 사용한 진동자극용 시트커버형 시제품과 모터드라이버모듈을 제작하였고 촉각이상이 없는 젊은 남녀 10명을 대상으로 6자유도 모션베이스 상에 구축된 가상운전 시뮬레이터를 사용하여 가상운전상황에서의 시트진동자극에 대한 실험을 진행하였다. 모터의 동작전압(1.5V, 2.5V, 3.5V)에 따라 세기가 가변되는 30개소의 진동자극의 위치별 인지율을 측정하여 분석하였다. 피험자들은 2.5V,3.5V로 동작하는 30개소의 모터 진동자극을 모두 인지하였고 최저작동전압인 1.5V에서도 일정수준 이상의 인지율을 보여주는 결과를 얻었으며 이 결과는 차량 내에서의 시트를 통한 진동자극의 운전정보 유용성을 보여주는 것으로 사료된다.

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CATV 홈쇼핑에서의 충동구매 자극 요인과 구매 경험과의 관련성 (The Relationship between Impulsive Buying Stimulus and Buying Experience in Cable TV Home Shopping)

  • 서미정;김혜선
    • 대한가정학회지
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    • 제42권3호
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    • pp.105-118
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    • 2004
  • Cable TV Home Shopping is one of the popular distribution channels in modem society because of purchasing convenience and saving in shopping time. However, in spite of these advantages, there are some problems because of marketing strategies of many Cable TV shopping companies which stimulate impulse purchases. This study is aimed to find the relationship between buying experience and reaction to impulsive buying stimulus. This study can give a valuable insight in consumer education regarding impulsive purchase behavior in Cable TV home shopping. Study results can also give useful information on the direction of consumer campaign and consumer protection policies. The data was collected by using a questionnaire and the final 496 cases were analyzed by SPSS Win 10.0 program. The major finding were that: 1. Younger, more educated and unmarried consumers tend to response more to impulsive purchasing stimulus. 2. consumers with higher response to impulsive purchasing stimulus had more buying experience, higher shopping frequencies and spent more money in Cable TV home shopping than consumers with lower response. These study results showed that there are some relationship between impulse purchasing stimulus and buying experience in Cable TV home shopping. Therefore, Cable TV Home Shopping companies should provide correct information to the consumers, so they can make resonable decisions. And the consumers should also try to restrain themselves from purchasing impulsively. A law that will regulate all false or exaggerated ads should be provided. To reach righteous and beneficial home shopping culture for both consumer and companies, all these means should be cooperated.

시각적 공간자극에 나타난 뇌파반응의 자극 정도와 만족도 변화특성 - 할로겐 조명과 벽의 영향을 중심으로 - (The Change Characteristic of the Stimulation and Satisfaction of the Brain Wave Reaction to the Visual Stimulation in the Space - Focus on the Influence of the Halogen and Wall -)

  • 서지은
    • 한국실내디자인학회논문집
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    • 제24권5호
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    • pp.99-107
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    • 2015
  • The purpose of this study is to analyze the change of visual stimulus of users to the space through the experiment of EEG and the satisfaction of users depends on the lighting. To do that, the results measured with EEG experiment focusing on Beta ${\beta}$ were compared to each other to figure out difference in the changes of the activation of human brain on lighting's situation as the lighting off and on in the same space. The difference in the results was verified according to the characteristic of users which classified with 4 types of the spatial sensitivities. The results of this study are as following. Firstly, the spacial sensitivity of user is to communicate well with the different senses with stimulus through interaction among the elements. At this time, the brain plays a major role in build the spacial sensitivity of users as the place to make form. Secondly, there are the differences in the activation of brain depends on lighting situation even in the same space. The stimulus into the brain became generally stronger in images with lighting on than off. Especially, the response in the occipital lobe which connected with the visual center turn out strongly in the image of 'modern natural'. Because the visual stimulus interact well with the bright color, the reflectional texture and the rough texture painted the dark color. Thirdly, the satisfaction of users changed with lighting in the space. But we could know that the satisfaction of users isn't be related to the visual stimulus through the results of this study. Finally, there isn't the difference in the activation degree of brain according to the characteristic which are preference of users into 4 types of the spatial sensitivity through the results came from ANCOVA(analysis of covariance) with SPSS Program 22.

시각 피질의 발화 특성 추출을 위한 포아송 모델의 부공간 해석 (Subspace analysis of Poisson Model to extract Firing Characteristics in Visual Cortex)

  • 이영석
    • 한국정보전자통신기술학회논문지
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    • 제15권1호
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    • pp.1-7
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    • 2022
  • 인간의 시각 피질을 구성하고 있는 시각 뉴런은 모든 시각적 자극에 반응하는 것이 아니라 특정한 조건을 갖춘 시각적 자극에 반응한다는 것이 생리학적 실험을 통하여 밝혀졌다. 본 연구에서는 이와 같은 생리학적 실험을 해석하기 위하여 랜덤한 이득을 갖는 선형 필터를 포함하는 뉴런의 발화 특성을 시뮬레이션하고 설명할 수 있는 모델을 제안하였고 또한 제안한 모델의 선형 필터의 출력이 전체 자극 데이터의 부공간을 형성하고 있음을 실험을 통하여 증명하였다. 구현된 모델의 타당성을 검증하기 위하여 서로 다른 4개의 시각적 자극 데이터들로부터 임의로 추출한 2개의 화소에 대한 값의 분포를 관찰하였다. 전체 자극 데이터와 스파이크 발화 자극 데이터의 분포로부터 중심 좌표 값 즉, 가장 많은 값이 분포하는 좌표 값을 추출하여 두 분포 사이의 차이를 확인할 수 있었고 구현된 모델이 전형적인 LNP 모델과 동일하게 전체 자극 데이터가 전체 집합일 경우 스파이크를 발생시키는 자극 데이터가 전체 자극 데이터의 부공간 임을 실험을 통하여 증명하였다. 본 연구는 시각적 자극에 대한 스파이크의 발생기전과 관련된 기초 연구로 활용할 수 있다.

Can Narrow Band Chirp Stimulus Shake the Throne of 500 Hz Tone Burst Stimulus for Cervical Vestibular Myogenic Potentials?

  • Ocal, F Ceyda Akin;Karacayli, Ceren;Coban, Volkan Kenan;Satar, Bulent
    • Journal of Audiology & Otology
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    • 제25권2호
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    • pp.98-103
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    • 2021
  • Background and Objectives: The aim of the study was to compare effects of tone-burst (TB) and narrow-band (NB) Claus Elberling (CE)-chirp stimuli on amplitude, latency and interaural asymmetry ratio (IAR) of cervical vestibular evoked myogenic potentials (cVEMP) in healthy individuals. Subjects and Methods: The study included 50 healthy volunteers. cVEMP procedure was carried out using 500 Hz TB and NB-CE-chirp stimulus (360-720 Hz, up-chirp) in random order. cVEMP were recorded at 100 dB nHL. For each ear and each stimulus, P1 latency, N1 latency and P1N1 amplitude were measured. IAR was also calculated. Results: Mean age was 26.66±9.48 years. cVEMP's in response to both TB and NB CE-chirp stimuli were obtained in all subjects. No statistically significant difference in P1 latency, N1 latency, and P1N1 amplitude was found between the right and left ears for both TB and NB CE-chirp stimuli (p>0.05). In both sides, P1 and N1 latencies were significantly shorter in NB CE-chirp stimulation compared to TB stimulation (p=0.000). In both sides, no statistically significant difference was found in P1N1 amplitude between two types of stimuli (p>0.05). Conclusions: The chirp stimulus produces robust but earlier cVEMP than TB does. This largest series study on NB chirp cVEMP shows that NB chirp is a good and new reliable alternative.