• 대한의용생체공학회:의공학회지
• /
• 제26권2호
• /
• pp.111-116
• /
• 2005

This study was designed to apply the stimulation system developed in our laboratory to investigate how the stimulation conditions affect the muscle contractile characteristics in the isometric condition as well as during the FES standing/walking. Four paraplegic and ten healthy subjects participated in this study, and their knee extensors were voluntary contracted or electrically stimulated to measure the muscle force and the fatigue index for different waveforms of the pulse train. We also investigated different combinations of the electrode positions during standing/walking. It was confirmed that continuous and high-frequency stimulation causes faster fatigue than intermittent and low-frequency stimulation. Fatigue resistance was higher around the optimal muscle length than at a stretched position in healthy subjects, whereas the opposite was observed in paralyzed subjects. The paired t-test results with the level of significance at 0.01 indicated that the sinusoidal waveform generated the largest torque among the four typical waveforms. Although statistically not very significant, the sinusoidal waveform also generated, in general, the highest fatigue resistance at an intensity level below the supramaximal stimulation. One of the paraplegic subject who participated in the standing/walking program can now stand up for 1 minute and 50 seconds with the knee extensors, and walk for about 5 minutes at the speed of 12m/sec.

• 한국통신학회논문지
• /
• 제41권7호
• /
• pp.809-815
• /
• 2016

본 논문은 줄기세포 재생 치료를 위해 사용되는 배지에 직류전압을 인가하여 배지에 반응되는 전기적인 저항 값, 전류 값 그리고 전압 값의 상태에 대해 분석하였다. 배지에 반응되는 전압은 줄기세포 분화 유도 과정에서 전기적인 자극에 연관되며 반응 전압 상태에 따라 분화의 상태에 대해 확인 할 수 있다. 배지의 반응 전압에서 전압변화 레벨이 적으면 줄기세포 자극 조건이 안정적이며 만일 전압 변화 레벨이 심하면 줄기세포 자극 조건이 불안정하여 줄기세포 분화 과정에서 상당한 손실을 따르게 될 수 있다. 본 연구는 줄기세포 재생 치료의 가능성을 위해 전기적인 자극 조건의 최적화 하는데 도움이 될 것으로 기대한다.

• 동력기계공학회지
• /
• 제14권4호
• /
• pp.29-36
• /
• 2010

인체에 음향진동장치에 의하여 자극을 가하였을 경우 영향을 고찰한다. 5명의 건강한 남자 대학생을 대상으로 하여, 3가지 형태의 음악을 음향과 진동자극의 신호원으로 사용해서 실험을 행하였다. 모든 피험자에 대하여, 자극 전, 음악자극, 진동자극, 자극 후로 나누어 뇌파를 측정하였다. 실험의 모든 피험자의 측정 데이터의 t-검정을 수행하여 유의성이 있는 데이터에 한하여 뇌파를 고찰하였다. 결과로서, 음악과 음향파와 진동자극이 뇌파에 미치는 영향은 음향진동장치에 따른 진동자극 형태, 피험자의 몸과 정신 상태에 따라 현저하게 달라질 수 있다는 것을 알 수 있다. 그리고 적절한 음악과 음향진동장치를 사용하여 특정의 뇌파 상태를 유도 할 수 있음을 확인하였다.

• 대한의용생체공학회:의공학회지
• /
• 제38권6호
• /
• pp.308-312
• /
• 2017

Skeletal muscle function plays a very important role in quality of life. However, skeletal muscle causes functional decline under aging or some diseases. Exercise and muscle training are good solutions to delay sarcopenia, but there are limitations to those who are uncomfortable in exercise. For this reason, alternative interventions for muscle sarcopenia are required, and many studies proved the increase of skeletal muscle mass by electrical stimulation. In conventional studies, however, mouse skeletal muscle cells have been mostly used in experiments to identify electrical stimulation conditions while human derived cells have not been frequently utilized in these studies. Stimulation used for rehabilitation has been uniformly treated without the consideration of aging. In addition, many studies have been used with conventional petri dish usually requiring many numbers of cells, which is not appropriate for rare. Moreover, they are not usually condition uniformity of electrical field. In this study, we have developed an electrical stimulation device which consumes a small amount of cells and can form a uniform electrical field. With the system, we analyzed the skeletal muscle differentiation and Myotube thickness depending on the electrical stimulation condition.

• 한국운동역학회지
• /
• 제26권1호
• /
• pp.93-99
• /
• 2016

Objective: The purpose of this study was to investigate the effect of transcutaneous electrical nerve stimulation (TENS) treatment on maximum voluntary force (MVF) production. Methods: Ten healthy, young subjects (5 males and 5 females) participated in the study. MVF was recorded after a fifteen minute session of TENS stimulation under two conditions: low frequency (4 Hz) at maximum tolerable level and high frequency (110 Hz) at maximum tolerable level. TENS was provided simultaneously via self-adhesive electrodes placed on the finger pads of the index, middle, ring and little fingers. MVF was also recorded in a baseline condition with no TENS treatment. Data were collected in three different sessions on three consecutive days at the sametime of the day. Results: Results from the study show that on an average, MVF increasesby 25% for the index, middle and little fingers for TENS treatment with 4 Hz frequency as compared to the baseline condition. However, the 110 Hz condition did not result in a significantly different MVF than the baseline condition during individual finger pressing tasks. In addition, while producing MVF with all the four finger stogether, MVF was 30% higher for the 4 Hz conditionin comparison to the baseline condition, and 15% higher for the 110 Hz condition in comparison to the baseline condition respectively. Conclusion: The results suggest that stimulation ofafferent fibers onthe glabrous skinwith TENS could have a net facilitatory effect on the maximum motoroutput.

• 대한의용생체공학회:학술대회논문집
• /
• 대한의용생체공학회 1992년도 춘계학술대회
• /
• pp.198-202
• /
• 1992

In this paper, we have performed an experiment to obtain an optimized electric stimulation condition on the tip or a ringer skin. The desired parameters for stimulation of the finger tip skin are waveforms, frequency, stimulation intensity, duty cycle. As a result, when the finger skin was stimulated with monophasic, biphasic, and differntial phasic, the most appropriate condition was 200 to 250[Hz] in frequency, 10 to 25[%] in duty cycle. Burst type pulse was more sensitive effect than that of continuous pulse methode.

• 한국정밀공학회지
• /
• 제24권1호
• /
• pp.101-109
• /
• 2007

In situations of spatio-temporal perception about visuo-auditory stimulus, researches propose optimal integration hypothesis that perceptual process is optimized to the interaction of the senses for the precision of perception. So, when the visual information considered generally dominant over any other sense is ambiguous, the information of the other sense like auditory stimulus influences the perceptual process in interaction with visual information. Thus, we performed two different experiments to certain the conditions of the interacting senses and influence of the condition. We consider the interaction of the visuo-auditory stimulation in the free space, the color of visual stimulus and sex difference of testee with normal people. In first experiment, 12 participants were asked to judge the change in the frequency of audio-visual stimulation using a visual flicker and auditory flutter stimulation in the free space. When auditory temporal cues were presented, the change in the frequency of the visual stimulation was associated with a perceived change in the frequency of the auditory stimulation as the results of the previous studies using headphone. In second experiment, 30 male and 30 female were asked to judge the change in the frequency of audio-visual stimulation using a color of visual flicker and auditory flutter stimulation. In the color condition using red and green. Both male and female testees showed same perceptual tendency. male and female testees showed same perceptual tendency however, in case of female, the standard deviation is larger than that of male. This results implies that audio-visual asymmetry effects are influenced by the cues of visual and auditory information, such as the orientation between auditory and visual stimulus, the color of visual stimulus.

• 한국산학기술학회논문지
• /
• 제16권5호
• /
• pp.3579-3586
• /
• 2015

본 논문은 온도 $25[^{\circ}C]$, 상대습도 50[RH%], 조도 1,000[lux] 및 기류 속도 0.02[m/sec]의 동일한 조건의 항온 항습실에서 감각자극에 노출되기 전, 쟈스민 향기 및 RED 조명의 단일감각자극, 쟈스민 향기와 RED 조명을 동시에 노출시킨 다감각 자극 변화에 따른 EEG, 학습능력, HRV 및 진동이미지를 측정하여 쾌적성, 집중력, 신체적 및 심리적 안정의 변화를 분석하였다. 연구결과 쟈스민 향기와 RED 조명의 다감각자극에서 상대 $S{\alpha}$파, SEF50, $SMR/{\theta}$ 및 SDNN이 향상되었고, 비대칭지수 $A_2$, 스트레스지수, 피로도 및 HRT는 감소하였다. 또한, 진동이미지의 긴장/불안과 스트레스는 감소하였다. 따라서 쟈스민 향기와 RED 조명의 다감각자극이 쾌적성, 작업능률의 생산성 및 주의집중력과 같은 뉴로에너지를 향상시키기 위하여 효과적인 것을 알 수 있었다.

• Korean Journal of Acupuncture
• /
• 제39권3호
• /
• pp.91-96
• /
• 2022

Objectives : The purpose of this study was to characterize the stimulation intensity in acupuncture manipulation techniques for tonification and sedation therapy. Methods : To describe the level of stimulation used in acupuncture manipulation techniques for tonification and sedation therapy, we reviewed the acupuncture manipulation techniques described in classical medical textbooks. Results : Based on the patients' conditions and pattern identification, acupuncture manipulation strategies for tonification and sedation therapy were chosen. For example, the excess condition was treated with sedative therapy, and the deficiency condition was treated with tonification therapy. For tonification therapy, weak to modest stimulation was applied in acupuncture manipulation techniques, whereas intense stimulation was applied for sedative therapy. Even though the intensity of acupuncture stimulation was chosen based on the clinical examination, deqi sensation is a crucial component of acupuncture treatment, and during acupuncture practice, the practitioner should choose the right intensity of acupuncture stimulation based on deqi response in each patient. Conclusions : We concluded that the tonifying and sedative effects of acupuncture treatment are related to the stimulation intensity of acupuncture manipulation techniques. For individualized medicine, the right amount of acupuncture stimulation should be administered based on the patients' conditions and responses, such as deqi responses.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2008년도 추계학술대회A
• /
• pp.1690-1691
• /
• 2008

Micro cell stimulation device is interested in many researchers because it has several advantages such as saving time and reagents. We introduce new micro-bioreactor using micro bead and conduct cell stimulation experiments to verify effective time because cell have operated by cell-cycle (G1, S, G2, and M phase). Micro-bioreactor was made by soft lithography and CAPE (calf pulmonary artery endothelial cell) was cultured in PDMS (polydimethylsiloxane) micro device for 12 hour and cell starvation process was performed for 24 hours. Micro glass beads were rolled only by slating device every hour during 15 hour because of minimizing other stimulation force like flow and pressure. The result represents that cells under exposed under micro bead stimulation show higher growth rate than normal condition and earlier and later stimulation time are more effective.