• 제목/요약/키워드: Statistical Model Validation

검색결과 261건 처리시간 0.024초

중규모 종합병원 대상 카바페넴 내성 장내세균속균종(Carbapenem-resistant Enterobacteriaceae) 획득위험 예측모형의 외적타당도 평가 (External Validation of Carbapenem-Resistant Enterobacteriaceae Acquisition Risk Prediction Model in a Medium Sized Hospital)

  • 서수민;정인숙
    • 대한간호학회지
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    • 제50권4호
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    • pp.621-630
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    • 2020
  • Purpose: This study was aimed to evaluate the external validity of a carbapenem-resistant Enterobacteriaceae (CRE) acquisition risk prediction model (the CREP-model) in a medium-sized hospital. Methods: This retrospective cohort study included 613 patients (CRE group: 69, no-CRE group: 544) admitted to the intensive care units of a 453-beds secondary referral general hospital from March 1, 2017 to September 30, 2019 in South Korea. The performance of the CREP-model was analyzed with calibration, discrimination, and clinical usefulness. Results: The results showed that those higher in age had lower presence of multidrug resistant organisms (MDROs), cephalosporin use ≥ 15 days, Acute Physiology and Chronic Health Evaluation II (APACHE II) score ≥ 21 points, and lower CRE acquisition rates than those of CREP-model development subjects. The calibration-in-the-large was 0.12 (95% CI: - 0.16~0.39), while the calibration slope was 0.87 (95% CI: 0.63~1.12), and the concordance statistic was .71 (95% CI: .63~.78). At the predicted risk of .10, the sensitivity, specificity, and correct classification rates were 43.5%, 84.2%, and 79.6%, respectively. The net true positive according to the CREP-model were 3 per 100 subjects. After adjusting the predictors' cutting points, the concordance statistic increased to .84 (95% CI: .79~.89), and the sensitivity and net true positive was improved to 75.4%. and 6 per 100 subjects, respectively. Conclusion: The CREP-model's discrimination and clinical usefulness are low in a medium sized general hospital but are improved after adjusting for the predictors. Therefore, we suggest that institutions should only use the CREP-model after assessing the distribution of the predictors and adjusting their cutting points.

An approach for simultaneous determination for geographical origins of Korean Panax ginseng by UPLC-QTOF/MS coupled with OPLS-DA models

  • Song, Hyuk-Hwan;Kim, Doo-Young;Woo, Soyeun;Lee, Hyeong-Kyu;Oh, Sei-Ryang
    • Journal of Ginseng Research
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    • 제37권3호
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    • pp.341-348
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    • 2013
  • Identification of the origins of Panax ginseng has been issued in Korea scientifically and economically. We describe a metabolomics approach used for discrimination and prediction of ginseng roots from different origins in Korea. The fresh ginseng roots from six ginseng cooperative associations (Gangwon, Gaeseong, Punggi, Chungbuk, Jeonbuk, and Anseong) were analyzed by UPLC-MS-based approach combined with orthogonal projections to latent structure-discriminant analysis multivariate analysis. The ginsengs from Gangwon and Gaeseong were easily differentiated. We further analyzed the metabolomics results in subgroups. Punggi, Chungbuk, Jeonbuk, and Anseong ginseng could be easily differentiated by the first two orthogonal components. As a validation of the discrimination model, we performed blind prediction tests of sample origins using an external test set. Our model predicted their geographical origins as 99.7% probability. The robust discriminatory power and statistical validity of our method suggest its general applicability for determining the origins of P. ginseng samples.

Modeling the Natural Occurrence of Selected Dipterocarp Genera in Sarawak, Borneo

  • Teo, Stephen;Phua, Mui-How
    • Journal of Forest and Environmental Science
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    • 제28권3호
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    • pp.170-178
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    • 2012
  • Dipterocarps or Dipterocarpaceae is a commercially important timber producing and dominant keystone tree family in the rain forests of Borneo. Borneo's landscape is changing at an unprecedented rate in recent years which affects this important biodiversity. This paper attempts to model the natural occurrence (distribution including those areas with natural forests before being converted to other land uses as opposed to current distribution) of dipterocarp species in Sarawak which is important for forest biodiversity conservation and management. Local modeling method of Inverse Distance Weighting was compared with commonly used statistical method (Binary Logistic Regression) to build the best natural distribution models for three genera (12 species) of dipterocarps. Database of species occurrence data and pseudoabsence data were constructed and divided into two halves for model building and validation. For logistic regression modeling, climatic, topographical and edaphic parameters were used. Proxy variables were used to represent the parameters which were highly (p>0.75) correlated to avoid over-fitting. The results show that Inverse Distance Weighting produced the best and consistent prediction with an average accuracy of over 80%. This study demonstrates that local interpolation method can be used for the modeling of natural distribution of dipterocarp species. The Inverse Distance Weighted was proven a better method and the possible reasons are discussed.

Genetic Parameter Estimates for Ultrasonic Meat Qualities in Hanwoo Cows

  • Lee, D.H.;Choudhary, V.;Lee, G.H.
    • Asian-Australasian Journal of Animal Sciences
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    • 제19권4호
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    • pp.468-474
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    • 2006
  • Real time ultrasound data was generated on 10,596 live Hanwoo cows to study genetic variation on ultrasonic beef quality traits and to assess the best model to estimate genetic parameters on these traits. Pedigree stacking and data validation was done using the SAS statistical software and the genetic parameter estimates were obtained by EM-REML algorithm. Out of the five different multi-trait mixed animal models constructed, the optimal model included fixed effects of herd, year-season-appraisal, body condition score, linear and quadratic covariates for chest girth, the linear covariate effect of age and the random animal and residual effect of the five models studied. The heritability of longissimus muscle area (LMA), $12^{th}$ rib measurement of back fat thickness (BF) and marbling score (MS) was 0.11, 0.17 and 0.15, respectively. Genetic correlation of LMA vs. BF, LMA vs. MS and BF vs. MS was -0.15, 0.06 and 0.61, respectively. The results showed presence of genetic variation in these ultrasonic beef quality traits in Hanwoo cows and suggest that the selection of Hanwoo cows may be possible by performing ultrasonic scans on live animals, which will ultimately be helpful in reducing the generation interval and the cost of selection procedure.

Visibility of Electric Distribution Utility Performance to Manage Loss and Reliability Indices

  • Honarmand, Mohammad-Esmaeil;Ghazizadeh, Mohammad-Sadegh;Kermanshah, Ali;Haghifam, Mahmoud-Reza
    • Journal of Electrical Engineering and Technology
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    • 제12권5호
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    • pp.1764-1776
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    • 2017
  • To achieve economic stability, distribution Company as an economic institution should be managed by various processes. In this way, knowledge of different processes is the first step. Furthermore, expectations, outputs, requirement data, and sub-processes should be extracted and determined. Accordingly, to assign the performance responsibility of each process, the decision-making points must be introduced and, the deviation or change in set-points should be investigated into processes. Also, the performance of processes could be monitored by introducing of the sub-indictors. In this study, a practical method is presented for monitoring of reliability and power loss indices from viewpoint components' supply chain into the distribution network. At first, the visibility model of the supply chain is illustrated by focus group and the sub-indicators are extracted for each process of this chain. Then, validation and verification of the sub-indicators are accomplished by the Delphi method and, an information dashboard is presented by confirmed the sub-indicators and statistics methods. Finally, the proposed method is investigated by real data in a typical network and the results are analyzed.

간호사의 스트레스 측정도구 개발 (Development of a Scale for Measuring Nurses' Stress)

  • 강윤희;이경미;허유진
    • 임상간호연구
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    • 제30권1호
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    • pp.11-23
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    • 2024
  • Purpose: This study developed a scale of nurses' stress and examined the validity and reliability of the scale. Methods: The scale was developed according to DeVellis' scale development procedure. Based on the Nursing Work Environment Stress model and the results of focus group interviews, 43 preliminary items were generated. A survey was conducted with 208 clinical nurses to test the psychometric properties of the scale. Both exploratory factor analysis and confirmatory factor analysis were employed to figure out and confirm the scale's theoretical structure statistically. In addition, content, convergent, and discriminative validity were evaluated and Cronbach's α was calculated to test internal reliability. Results: The final scale consisted of 19 items and verified four-factor structures. The structure of the scale was confirmed using confirmatory factor analysis, and it showed moderate correlations with the Copenhagen Burnout Inventory and Korean Nurses Occupational Stress Scale. Cronbach's α was .87. Conclusion: A scale of nurses' stress to nursing work was developed to embrace a wide range of nurses' psychological responses to nursing work based on the theoretical model.

Variable Density Yield Model for Irrigated Plantations of Dalbergia sissoo Grown Under Hot Arid Conditions in India

  • Tewari, Vindhya Prasad
    • Journal of Forest and Environmental Science
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    • 제28권4호
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    • pp.205-211
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    • 2012
  • Yield tables are a frequently used data base for regional timber resource forecasting. A normal yield table is based on two independent variables, age and site (species constant), and applies to fully stocked (or normal) stands while empirical yield tables are based on average rather than fully stocked stands. Normal and empirical yield tables essentially have many limitations. The limitations of normal and empirical yield tables led to the development of variable density yield tables. Mathematical models for estimating timber yields are usually developed by fitting a suitable equation to observed data. The model is then used to predict yields for conditions resembling those of the original data set. It may be accurate for the specific conditions, but of unproven accuracy or even entirely useless in other circumstances. Thus, these models tend to be specific rather than general and require validation before applying to other areas. Dalbergia sissoo forms a major portion of irrigated plantations in the hot desert of India and is an important timber tree species where stem wood is primarily used as timber. Variable density yield model is not available for this species which is very crucial in long-term planning for managing the plantations on a sustained basis. Thus, the objective of this study was to develop variable density yield model based on the data collected from 30 sample plots of D. sissoo laid out in IGNP area of Rajasthan State (India) and measured annually for 5 years. The best approximating model was selected based on the fit statistics among the models tested in the study. The model develop was evaluated based on quantitative and qualitative statistical criteria which showed that the model is statistically sound in prediction. The model can be safely applied on D. sissooo plantations in the study area or areas having similar conditions.

급성심근경색증 환자의 진료 질 평가를 위한 병원별 사망률 예측 모형 개발 (Development of a Model for Comparing Risk-adjusted Mortality Rates of Acute Myocardial Infarction Patients)

  • 박형근;안형식
    • 한국의료질향상학회지
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    • 제10권2호
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    • pp.216-231
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    • 2003
  • Objectives: To develop a model that predicts a death probability of acute myocardial infarction(AMI) patient, and to evaluate a performance of hospital services using the developed model. Methods: Medical records of 861 AMI patients in 7 general hospitals during 1996 and 1997 were reviewed by two trained nurses. Variables studied were risk factors which were measured in terms of severity measures. A risk model was developed by using the logistic regression, and its performance was evaluated using cross-validation and bootstrap techniques. The statistical prediction capability of the model was assessed by using c-statistic, $R^2$ as well as Hosmer-Lemeshow statistic. The model performance was also evaluated using severity-adjusted mortalities of hospitals. Results: Variables included in the model building are age, sex, ejection fraction, systolic BP, congestive heart failure at admission, cardiac arrest, EKG ischemia, arrhythmia, left anterior descending artery occlusion, verbal response within 48 hours after admission, acute neurological change within 48 hours after admission, and 3 interaction terms. The c statistics and $R^2$ were 0.887 and 0.2676. The Hosmer-Lemeshow statistic was 6.3355 (p-value=0.6067). Among 7 hospitals evaluated by the model, two hospitals showed significantly higher mortality rates, while other two hospitals had significantly lower mortality rates, than the average mortality rate of all hospitals. The remaining hospitals did not show any significant difference. Conclusion: The comparison of the qualities of hospital service using risk-adjusted mortality rates indicated significant difference among them. We therefore conclude that risk-adjusted mortality rate of AMI patients can be used as an indicator for evaluating hospital performance in Korea.

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데이터마이닝 기법을 활용한 맞춤형 고혈압 사후관리 모형 개발 (A Development of a Tailored Follow up Management Model Using the Data Mining Technique on Hypertension)

  • 박일수;용왕식;김유미;강성홍;한준태
    • 응용통계연구
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    • 제21권4호
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    • pp.639-647
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    • 2008
  • 본 연구는 국민건강보험공단의 건강검진데이터, 자격 및 보험료 그리고 진료비 데이터를 활용하여 고혈압 관리를 위한 맞춤형 고혈압 사후관리모형(고혈압 진료예측모형 및 고혈압 진료순응도세분화모형)을 개발하고자 하였다. 모형 개발에는 데이터마이닝의 로지스틱 회귀모형, 의사결정나무 그리고 앙상블 모형을 활용하였다. 고혈압 진료예측모형에서는 3가지 모형 중 로지스틱 회귀모형이 가장 우수한 모형으로 채택되었으며, 고혈압 진료순응도세분화모형은 의사결정나무모형을 통해 개발되었다. 본 연구는 전국 규모의 수년간 축적된 자료를 데이터마이닝을 활용함으로써 고혈압의 진료 및 진료순응도에 이르는 고혈압 사후관리 프로세스 전반에 걸친 결과를 도출함으로써 우리나라 고혈압 사후관리체계 구축에 기여할 것으로 사료된다.

파장별 회체가스중합모델을 이용한 대향류 화염에서의 복사 흡수 예측에 관한 연구 (A Study on the Prediction of Self-absorption in Opposed Flames Using WSGGM-Based Spectral Model)

  • 김욱중
    • 대한기계학회논문집B
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    • 제25권4호
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    • pp.600-609
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    • 2001
  • WSGGM based low-resolution spectral model for calculating radiation transfer in combustion gases is applied to estimate self-absorption of radiation energy in one-dimensional opposed flow flames. Development of such a model is necessary in order to enable detailed chemistry-radiation interaction calculations including self-absorption. Database of band model parameters which can be applied to various one-dimensional opposed flow diffusion and partially premixed flames is created. For the validation of the model and database, low resolution spectral intensities at fuel exit side are calculated and compared with the results of a narrow band model with those based on the Curtis-Godson approximation. Good agreements have been found between them. The resulting radiation model is coupled to the OPPDIF code to calculate the self-absorption of radiant energy and compared with the results of an optically thin calculation and the results of a discrete ordinates method in conjunction with the statistical narrow band model. Significant self-absorption of radiation is found for the flames considered here particularly for the fuel side of the reacting zone. However, the self-absorption does not have significant effects on the flame structure in this case. Even in the case of the low velocity diffusion flame and the partially premixed flame of low equivalence ratio, the effects of self-absorption of radiation on the flame temperature and production of minor species are not significant.