• 약학회지
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• 제59권6호
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• pp.251-258
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• 2015

Aim of the present study was to investigate whether methanol extract from the leaves of Staphylea bumalda could be used to suppress lipopolysaccharide (LPS)-induced inflammatory responses in murine macrophage cell lines, Raw 264.7 cells. The extract reduced nitric oxide (NO), cyclooxigenase-2 (COX-2) and pro-inflammatory cytokines production from LPS-stimulated Raw 264.7 cells. These inhibitory effects were associated with decreases in the phosphorylation of MAP kinases and the activity of $NF{\kappa}B$ signal pathways. Our results indicate that Staphylea bumalda significantly inhibits the inflammatory activity of activated macrophages, suggesting that Staphylea bumalda could be a potential candidate for the treatment of inflammatory disease.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.86-86
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• 2020

The leaves of Staphylea bumalda (S. bumalda) as a deciduous tree distributed in Korea, China and Japan are used to treat respiratory diseases or inflammation. However, there is no scientific research on the immune-enhancing activity of S. bumalda leaves. Thus, in this study, we investigated the effect of water extracts from S. bumalda leaves (SBL) on the macrophage activity using mouse macrophage cells, RAW264.7. SBL increased production of immunomodulators such as NO, iNOS, IL-1β, IL-6, TNF-α and MCP-1 in RAW264.7 cells and activated phagocytic activity of RAW264.7 cells. Inhibition of TLR2 and TLR4 blocked SBL-mediated production of immunomodulators in RAW264.7 cells. In addition, SBL-mediated production of immunomodulators was attenuated by JNK inhibition in RAW264.7 cells. SBL increased JNK phosphorylation, while Inhibition of TLR2 and TLR4 blocked SBL-mediated JNK phosphorylation in RAW264.7 cells. These results are thought to be evidence that SBL activates JNK through stimulation of TLR2 and TLR4 in macrophage to induce the production of immunomodulators. In LPS-stimulated RAW264.7 cells, SBL inhibited over-production of immunomodulators. Summarizing the results, SBL showed immunostimulatory activity under normal conditions and immunosuppressive activity under LPS-induced excessive immune response conditions.

• Natural Product Sciences
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• 제10권4호
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• pp.173-176
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• 2004

Six compounds were isolated from the BuOH soluble fraction of the leaves of Staphylea bumalda. On the basis of spectral data, they were identified as atragalin (1), $2-methyl-5,\;7-dihydroxy-chromone-7-O-{\beta}-D-glucopyranoside$ (2), isoquercitrin (3), nicotiflorin (4), kaempferol 3-neohesperidoside (5), kaempferol $3-O-[{\alpha}-rhamno-pyranosyl-(1\;{\to}\;4)-rhamnopyranosyl-(1\;{\to}\;6)-{\beta}-D-glucopyranoside]$ (6), respectively.

• The Korean Journal of Ecology
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• 제17권4호
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• pp.471-484
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• 1994

The forest vegetation types and their structural characteristics in Mt. $Mud\v{u}ng$ were investigated by classification method and ordination method. The forest was classified into 7 communities by ristic composition table: Quercus monogolica community, Q. serrata community, Q.acutissima community, Q.variabilis community, Q.dentata community, Pinus densiflora community and Frainus mandshurica community. Considering the moisture gradient, two kinds of distributuin pattern were shown as follows; F. mandshurica, Q. acturissima, Platycarya strobilacea and Staphylea bumalda were distribute at moist habitats, while Q. monogolica, P. densiflora and Q.variabilis at dry habitats. In continuum analysis, each population occupied different distribution area but it was continuously overlapped. On the successional trends of tree species, it is postulated that Q. mongolica species might dominate the altitudinal zone over 700m.

• 한국조경학회지
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• 제21권1호
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• pp.139-148
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• 1993

The present experiments have been conducted to find out the plant's growth environments habitate, mode of life, characteristic of photosynthesis, habit of growth and propagation. The results of this study are as follows: 1. Sambucus williamsii var. Coreana distributes around all sides of native site without having any relation to altitude, inclination and direction. 2. In the native site, Robinia pseudo - acacia and its neighboring species were Prunus yedoensis, Acer pseudo-sieboldianum, Lindera obtusiloba and Staphylea bumalda. From 21 to 41 types of species were located in the vegetation of the quadrat area. 3. According to the variation of leaf temperature with the result of the change of net photosynthetic rate, the optimum temperature for growth is $25^{\circ}C$. 4. The rooted rate of vegetative propagation was the highest at 100ppm IBA plot and the lowest at 200ppm BA plot. 5. The rooted rates of Sambucus williamsii var. coreana in perlite 50% bed, vermiculite bed and peatmoss 50%+sand 50% bed are higher than others.

• 한국농림기상학회지
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• 제6권3호
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• pp.183-189
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• 2004

저장 기간이 서로 다른 종자들을 대상으로 저장 기간에 따른 종자 특성 및 발아특성 변화를 조사하고, 적정 저장 기간 및 저장 조건을 찾고자 실시하였다. 물푸레나무, 산초나무 및 고추나무의 종자는 -18$^{\circ}C$에서 1년, 3년, 10년간 저장된 것을 이용하였으며, 수종별 종자 및 발아 특성과 유묘의 생장 및 생리적 특성을 조사하였다. 3개 수종의 종자 및 발아 특성은 저장 기간 및 수종별 차이를 뚜렷하게 보여주었다. 물푸레나무와 고추나무 종자의 수분함량은 저장기간이 길어지면서 감소하는 경향을 나타냈다. 또한 종자의 무게도 저장기간이 길어지면서 감소하였는데, 특히 산초나무의 10년간 저장 종자의 생중량 감소가 뚜렷하였으며, 충실율도 10년간 저장 후 크게 낮아졌다. 저장기간은 물푸레나무 및 고추나무 종자의 수분함량 또는 고추나무 종자의 생중량과 부의 상관(r=-0.822, p<0.01)을 나타냈다. 3년 이상 저장된 산초나무 종자의 발아율은 15% 이하로 감소하였으며, 3년간 저장된 고추나무 종자의 발아율은 10.1% 이하로 급격히 하락하였다. 또한 평균발아소요일수는 종자 저장기간이 길어지면서 증가하였는데, 10년간 저장된 물푸레나무, 산초나무 및 고추나무 종자의 평균발아소요일수는 11.9일, 5.7일, 9.7일씩 각각 증가하였다. 물푸레나무와 고추나무 종자의 평균발아소요일수는 수분함량과 부의상관을 보여주었으며, 저장기간과는 정의 상관을 보였다. 그러나 종자의 저장기간에 따른 유묘의 생장 및 활력 차이는 일정한 경향을 나타내지 않았다.

• 농약과학회지
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• 제7권4호
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• pp.248-257
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• 2003

본 연구의 목적은 국내의 자생식물 중 살초활성이 있는 식물 종을 선발하는데 있다. 국내의 자생식물 73과(科) 200종(種) 시료로부터 MeOH 조추출물을 얻은 다음 24-well plate에서 유채 (Brassica napus L.) 에 대한 살초효과를 검정하였다. 실험에 사용한 200종 식물 중 6종 식물 - 고추나무 (Staphylea bumalda), 등나무(Wistaria floribunda), 산마늘(Allium victorialis), 소리쟁이(Rumex crispus), 이팝나무(Chionanthus retusa), 참느릅 나무 (Ulmus parvifolia)는 높은 살초활성을 나타내었고 ($GR_{50}$ 값, < $1,000{\mu}g\;g^{-1}$), 17종 식물 - 갈퀴덩굴(Galium spurium), 느티나무(Zelkova serrata), 능소화(Campsis gradiflora), 두충(Eucommia ulmoides), 마가목(Sorbus commixta.), 물참대(Deutzia glabrata), 박태기나무(Cercis chinensis), 산오리(Alnus hirsuta), 산초나무(Zanthoxylum schinifolium), 상수리나무(Quercus acutissima), 아까시나무(Robinia pseudoacacia), 주엽나무(Gleditsia japonica), 죽단화(Kerria japonica), 쥐똥나무(Ligustrum obtusifolium), 측백나무(Thuja orientalis), 편백(Chamaecyparis obtusa), 할미꽃(Pulsatilla koreana)은 중정도의 살초활성을 나타내었으나($GR_{50}$ 값, $1,000-2,000{\mu}g\;g^{-1}$), 나머지 177종 식물은 살초활성을 나타내지 않았다. 높은 살초활성을 나타낸 식물로부터 분리되는 천연활성물질들은 향후 새로운 제초제 개발을 위한 모화합물 제공, 상호대립억제 작용성을 갖는 작물 품종 개발 혹은 개량에의 활용, 그리고 친환경 유기농업용 잡초방제에의 활용이 기대된다.

• 한국조경학회지
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• 제15권2호
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• pp.67-78
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• 1987

This study was executed to measure the user\`s impact natural environment in National Park Campsite. Therefore, we choose Mt. Chiak National Park and the campsite in the district of Temple Ku-Ryong as a model of analysis, which is made by ecological approach, the number of the user has influence on the environment near the campsite. The result are as follows : 1. The more the number of users becomes, the more Na, Ca, Mg ion concentration and pH in the soil increase and the less K ion becomes. 2. Litter and humus depth, litter coverage, herb coverage, soil hardness, the surface of the ground layer and tree species numbers, density and coverage of lower layer shows a sensitive reaction to the number of the users. 3. The research shows that the tolerant trees against campsite impact are Lespedeza maximowiczii, Zanthoxylum schinifolium Staphylea bumalda, Smilax sieboldii, Quercus aliena, Euonymus oxyphyllus, Weigela subsessilis and Securinega suffruticosa, and the sensitive trees are Stephanandra incisa, Rubus trichocarpa, Rubus crataegifolius, Rhododendron mucronulatum, Styrax obassia, Acer palmatum, Lindera obtusiloba, Rhododendron suhlippenbachii, Rhus japonica and Callicarpa japonica. 4. The high density of the users made the simplication of a vegetation structure. So, as the number of the user increase the species showed severe heterogeniety between the heavy-use and nonuse site. 5. As considering the landscape management about campsite and surrounding area on the way of analysis of national landscape aspect and succession sere according to ecological aspect, it may be desirable that Pinus densiflora forest be conserved as Pinus densiflora landscape and mixed forest produce natural scenery with succession sere.

• 한국조경학회지
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• 제21권4호
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• pp.83-99
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• 1994

To compare basic information and to inspect impacts situations between 1987 and 1992, this study was executed in Chongnung valley of Mt. Puk'an. And to provide basic informations through the change of plant species diversity, some methods were applied and analyzed such as the degree of environmental impacts and belt-transect method. The results were summarized as follows; 1. In order to find environmental impacts by visitor, the degree of environmental impacts class that was proposed by Kwon(1991) was implicated. In 4 sites, total area of over impact class 2 is 86,692$m^2$ and area of impacts class 4-6 that is impossible to recover naturally is 36,856$m^2$. Totally, the impacted area was profounded qualitatively and quantitatively against 1987's. 2. In the vegetation change by visitor's impacts, species diversity was rapidly decreased as nearer the campsite and trail. And in the basal area and coverage, lower layer species was sensitively changed. Trampling-resistent species is as following; Robinia pseudoacacia, Lespedeza cyrtobotrya, Staphylea bumalda, Clerdendron trichotomum, Stephanandra incisa, Rubus crataegifolius, Lespedeza maximowiczii, Weigela subsessilis, Rosa multiflora, Zanthoxylum schinifolium, Lindera obtusiloba, Callicarpa japonica, Sorbus alnifolia, Symplocos mongolica and so on. In the results of soil hardness test, that was decreased as far away from campsite and trail. 3. In the 4 sites selected in Chongnung valley of Puk'ansan Natioal Park, management plans was largely divided 4 category, such as trail improvement, facilities setting, ecotone vegetation establishment, and vegetation rehabilitation. And a suggestion was provided to each site.

• Journal of Forest and Environmental Science
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• 제16권1호
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• pp.69-81
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• 2000

본 연구는 오대산 국립공원내 월정사지역에 분포하고 있는 전나무림의 식생구조를 분석하여 이 지역 전나무림의 관리에 대한 기초자료를 제공하기 위하여 수행되었다. 그 결과 전나무림의 층위구조는 교목층(2종류), 아교목층(20종류), 관목층(46종류) 그리고 초본층(87종류)으로 구성되어있었다. 조사지역에 출현한 전체식물의 중요치는 전나무가 34.09%로 가장 높게 나타났고, 당단풍(23.07%), 청시닥나무(14.44%), 고광나무(10.72%), 오리방풀(8.49%), 복자기 (7.80%), 고추나무(7.65%), 산거울(6.79%), 방아풀(5.76%), 고로쇠나무 (5.47%), 개다래(5.4%)의 순으로 나타났다. 특히, 전나무의 치수가 전혀 없어 앞으로 아교목층과 관목층을 형성하고 있는 단풍나무류, 참나무류, 피나무류 등의 경쟁에 의하여 천이가 있을 것으로 사료된다.