• 대한통합의학회지
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• 제10권1호
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• pp.27-38
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• 2022

Purpose : This study is aimed to develop and validate the clinical practice education program and clinical competence scale of occupational therapy student. Methods : The development of the clinical practice education program used the delphi technique method, which had a total of five steps. Based on the occupational therapist's job analysis, the first stage assessed the importance of 21 experts, and the second stage examined the importance of 19 new specialists to derive constitutive factors. In the third stage, in-depth interviews were conducted with three experts based on the derived factors, and in the fourth stage, the final clinical practice education program was derived. In the final stage, the details of the clinical training program were drawn up based on the themes and were reviewed by two experts. Structured and unstructured interviews were conducted with 43 job experts. Results : The expert survey through the delphi technique was conducted three times, and content analysis and descriptive statistics were conducted to examine the distribution of responses. The final 11 educational program topics and contents were derived. Topics are confirmation of client information, evaluation and intervention, cognitive therapy, spinal cord injury, brain injury, musculoskeletal disorders, pediatric occupational therapy, interventions in activities of daily living, driving rehabilitation, vocational rehabilitation, occupational therapy assessment tool, safety training and management. Conclusion : The clinical practice education program reduce the difference between school education and clinical education of occupational therapy student. Occupational therapy helps college student understand occupational therapy practices and improve the quality of clinical education. Through more research and supplementation of clinical practice education programs in the future, it is suggested that clinical practice education be successfully operated in various practice institutions and used as basic data for designing and evaluating useful educational models.

• 한국구조물진단유지관리공학회 논문집
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• 제19권2호
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• pp.143-150
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• 2015

현재 국내 모듈러 구조물은 저층의 단독주택 및 군 병영생활관에 한정되어 있는 실정이며, 적층식 모듈러 구조물에 대한 표준화된 구조설계 방법이 없으므로 구조물의 시공과정에서 모듈의 양중이나 운송 시 발생되는 관성력, 양중 시 구조물에 대한 풍하중의 영향, 모듈의 적층 설치 시 충격력 등에 대한 검토가 일반적으로 이루어지고 있지 않다. 따라서 본 연구에서는 대상 모듈러 시스템에 대한 단계별 시공방법을 살펴보고, 각 시공단계에 대한 구조해석 시 경계조건 및 하중 작용위치를 결정하였다. 또한 모듈의 양중 및 차량운반 시 각각의 속도에 따른 관성력을 산정하였으며 모듈의 적층설치 작업 시 양중속도에 따른 충격하중과 양중에 의한 설치작업 시 순간풍속에 의한 풍하중을 산정하였다. 제안된 방법을 토대로 대상 모듈러 시스템에서 양중 시와 운송 시, 설치 시 등 시공단계별 하중크기 결정조건을 변화시켜 구조검토를 수행하였으며 구조적으로 안전성이 확보되는 시공조건을 도출하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.4103-4107
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• 2015

Background: Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide. Transarterial chemoembolisation (TACE) is the standardized therapy for intermediate stage HCC. However, the prognosis for HCC patients treated by TACE greatly varies. Thus, there is a critical need for finding biomarkers to predict the prognosis of HCC patients. The amino acid transporter-2 (ASCT2) is involved in tumorigenesis and progression of many malignancies. This study aimed to evaluate the predictive role of two single nuclear polymorphisms (SNPs, rs3826793 and rs2070246) in the ASCT2 gene in HCC patients treated by TACE. Materials and Methods: Two functional SNPs (rs3826793 and rs2070246) in the ASCT2 gene were selected and genotyped using the Sequenom iPLEX genotyping system in a cohort of 448 unresectable Chinese HCC patients treated by TACE. Univariate and multivariate Cox proportional hazards models and Kaplan-Meier curves were used for the prognosis analyses. Results: There was no significant association between two SNPs (rs3826793 and rs2070246) in the ASCT2 gene and overall survival of TACE treated HCC patients. However, we demonstrated that patients with early stage HCC carrying T genotype in rs2070246 showed better OS than those carrying CC genotype (P=0.023). Conclusions: We demonstrated that patients with early stage HCC carrying T genotype in rs2070246 showed better OS than those carrying CC genotype.

• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2895-2899
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• 2016

Background: Increasing breast cancer (BC) incidence rates have been reported from India; causal factors for this increased incidence are not understood and diagnosis is mostly in advanced stages. Trivandrum exhibits the highest BC incidence rates in India. This study aimed to estimate trends in incidence by age from 2005-2014, to predict rates through 2020 and to assess the stage at diagnosis of BC in Trivandrum. Materials and Methods: BC cases were obtained from the Population Based Cancer Registry, Trivandrum. Distribution of stage at diagnosis and incidence rates of BC [Age-specific (ASpR), crude (CR) and age-standardized (ASR)] are described and employed with a joinpoint regression model to estimate average annual percent changes (AAPC) and a Bayesian model to estimate predictive rates. Results: BC accounts for 31% (2681/8737) of all female cancers in Trivandrum. Thirty-five percent (944/2681) are <50 years of age and only 9% present with stage I disease. Average age increased from 53 to 56.4 years (p=0.0001), CR (per $10^5$ women) increased from 39 (ASR: 35.2) to 55.4 (ASR: 43.4), AAPC for CR was 5.0 (p=0.001) and ASR was 3.1 (p=0.001). Rates increased from 50 years. Predicted ASpR is 174 in 50-59 years, 231 in > 60 years and overall CR is 80 (ASR: 57) for 2019-20. Conclusions: BC, mostly diagnosed in advanced stages, is rising rapidly in South India with large increases likely in the future; particularly among post-menopausal women. This increase might be due to aging and/or changes in lifestyle factors. Reasons for the increased incidence and late stage diagnosis need to be studied.

• 스마트미디어저널
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• 제11권7호
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• pp.19-27
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• 2022

인공지능 소프트웨어 시장은 2020년부터 2025년까지 6배 규모로 성장할 것으로 예상된다. 그러나 소프트웨어의 개발 절차가 표준화 되어 있지 않고 비용 산정 기준이 없다. 이에 따라 인공지능 소프트웨어 개발 업체마다 각자의 개발 절차에 따른 투입 공수를 산정하고 이를 개발비용의 근거로 제시하고 있으나 개발업체마다 상이한 개발 절차와 소요 공수의 규모 때문에 품질과 비용에 대한 불신이 커지고 있다. 본 연구에서는 대량의 데이터로 학습을 진행하고 알고리즘을 도출하여 적용하는 인공지능 기반 소프트웨어의 개발단계를 정의하고 개발업체들을 대상으로 개발단계별 소요 공수에 대한 설문을 진행하여 소요 공수를 수집하였다. 수집된 개발단계별 소요 공수간의 상관분석과 회귀분석을 실시하여 개발단계별 소요 공수 예측 모형을 도출하였으며, 모형을 실험한 결과, 수집된 소요 공수 대비 92%의 정확도를 보였다. 본 연구에서 제안한 소요 공수 예측 모형은 공수와 비용을 추정하는데 간단하게 활용할 수 있는 도구가 될 것으로 기대된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제38권4호
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• pp.212-220
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• 2012

Objectives: Fluorine-18 fluorodeoxyglucose positron emission tomography ($^{18}F$-FDG PET) is a non-invasive diagnostic tool for many human cancers wherein glucose uptake transporter-1 (GLUT-1) acts as a main transporter in the uptake of $^{18}F$-FDG in cancer cells. Increased expression of glucose transporter-1 has been reported in many human cancers. In this study, we investigated the correlation between $^{18}F$-FDG accumulation and expression of GLUT-1 in oral cancer. Materials and Methods: We evaluated 42 patients diagnosed with oral squamous cell carcinoma (OSCC) and malignant salivary gland tumor as confirmed by histology. 42 patients underwent pre-operative $^{18}F$-FDG PET, with the maximum standardized uptake value ($SUV_{max}$) measured in each case. Immunohistochemical staining was done for each histological specimen, and results were evaluated post-operatively according to the percentage (%) of positive area, intensity, and staining score. Results: For OSCC, $SUV_{max}$ significantly increased as T stage of tumor classification increased. For malignant salivary gland tumor, $SUV_{max}$ significantly increased as T stage of tumor classification increased. For OSCC, GLUT-1 was expressed in all 36 cases. GLUT-1 staining score (GSS) increased as T stage of tumor classification increased, with the difference statistically significant. For malignant salivary gland tumor, GLUT-1 expression was observed in all 6 cases; average GSS was significantly higher in patients with cervical lymph node metastasis than that in patients without cervical lymph node metastasis. Average GSS was higher in OSCC ($11.11{\pm}1.75$) than in malignant salivary gland tumor ($5.33{\pm}3.50$). No statistically significant correlation between GSS and $SUV_{max}$ was observed in OSCC or in malignant salivary gland tumor. Conclusion: We found no statistically significant correlation between GSS and $SUV_{max}$ in OSCC or in malignant salivary gland tumor. Studies on the various uses of GLUT during $^{18}F$-FDG uptake and SUV and GLUT as tumor prognosis factor need to be conducted through further investigation with large samples.

• 한국건설관리학회논문집
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• 제17권4호
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• pp.3-11
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• 2016

최근 국내 기업의 해외 플랜트 수주는 꾸준히 증가하는 추세이며, 2014년 상반기의 수주액은 전년도 대비 93% 이상 크게 증가되었다. 또한, 2015년 3사분기가 지난 현재, 해외 플랜트 수주액은 이미 2,498억 달러를 넘어섰다고 조사된 만큼 플랜트 산업에 대한 관심이 증가되고 있다. 플랜트 프로젝트의 생애주기 중 시공 이전 단계의 건설 사업관리(CM)는 사업 초기 단계에 내재된 불확실성을 보완하고, 합리적인 의사결정을 지원한다는 측면에서 그 역할의 중요성이 대두되고 있다. 그 중에서도 사업 기획 단계의 사업 발굴 및 사업 참여방안 검토 업무는 향후 사업의 성공과 실패를 좌우할 수 있는 큰 영향력을 가진 중요한 업무이지만, 의사결정을 위한 각 분야 간의 빈번한 협의, 그리고 이에 따른 계속된 수정, 변경 등과 비효율적인 반복 작업이 문제가 되고 있다. 따라서 이를 효과적으로 수용할 수 있는 업무 프로세스의 변화가 필요하게 되었고, 본 논문에서는 플랜트 프로젝트 기획 단계의 '사업 발굴 및 사업 참여방안 검토'를 대상으로 주요 업무 항목을 도출하고 전문가 자문을 활용한 델파이 분석을 통해 표준화된 업무 프로세스를 정립하였다. 본 논문의 결과는 우리나라 EPC 기업이 해외시장에서 기획 분야의 기술 경쟁력을 확보하고 업무 효율성을 제고할 수 있는 기반을 마련하는 데에 활용될 수 있을 것으로 기대된다.

• 대한치과보철학회지
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• 제41권3호
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• pp.271-287
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• 2003

Statement of problem: Resonance frequency analysis (RFA) has been increasingly served as a non-invasive and objective method for clinical monitoring of implant stability. Many clinical studies must be required for standardized baseline data using RFA. Purpose: This study was performed to evaluate RFA value changes in two stage surgery group and one stage surgery group in patients. Material and method: Forty-seven mandibles in consecutively implant installed patients were selected for this study and 141 fixtures were installed. Ninety-three fixtures were double threaded, machined surface design ($Br{\aa}anemark^{(R)}$ MK III, Nobel Biocare AB, Goteborg, Sweden) and 48 fixtures were root form, threaded, HA-coated surface one ($Replace^{TM}$, Steri-Oss/Nobel Biocare AB, USA). Among those, each 10 fixture was installed in one stage group patients. ISQ values were measured using $Osstell^{TM}$ (Integration Diagnostics Ltd. Sweden) during fixture installation, at healing abutment connection and in the loading period for two stage surgery group patients and during at each 4, 6, 8, 10, 12week and in the loading phase for one stage surgery group patients and evaluated the changes according to the time and fixture type. Results: In two stage surgery group, mean and SO of ISQ values of machined surface implants were $76.85{\pm}3.74,\;75.76{\pm}5.04,\;75.73{\pm}4.41$ and those of HA-coated surface implant were $75.05{\pm}6.23,\;77.58{\pm}5.23,\;78.32{\pm}4.29$ during fixtures installation, at healing abutment connection and in the loading period, respectively. In one-stage surgery group, the ISQ values of machined surface and HA-coated surface implants decreased until 4 or 6 week and maintained at plateau for 1-3 week and increased to the loading period. Conclusions: Machined and HA-coated surface implants showed minimal ISQ changes with time if they were installed at the sites showing at least intact cortical plate and good bone qualities. And HA-coated implants had a tendency to show somewhat increased ISQ values with time.

• 성인간호학회지
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• 제21권6호
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• pp.666-677
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• 2009

Purpose: This study was to test a theoretical model examining the relationships among social support, illness demands, marital adjustment, family coping and family functioning in couples more than three years after breast cancer diagnosis. Methods: A causal modeling methodology was used to test the specified relationships in the recursive theoretical model. A total of 60 couples with breast cancer were recruited from January to April 2005. Five standardized questionnaires were used to measure the theoretical concepts: social support (ISSB), illness demands (DOII), marital adjustment (DAS), family coping (F-COPES), and family functioning (FACESII). Results: Path analysis results from the wives and the husbands revealed different patterns. Three hypotheses were supported in the wife model as predicted: social support and family coping, family coping and family functioning, and social support and marital adjustment (trend). Five hypotheses were supported in the husband model as predicted: social support and illness demands, also social support and marital adjustment, illness demands and marital adjustment, marital adjustment and family coping, and family coping and family functioning. Conclusion: This study provides valuable information for developing various interventions with social support for improving family functioning of breast cancer couples in the middle adaption stage (more than three years after diagnosis).

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.2606-2611
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• 2003

Comprehensive study on the control system design for a RTP process has been conducted. The purpose of the control system is to maintain maximum temperature uniformity across the silicon wafer achieving precise tracking for various reference trajectories. The study has been carried out in two stages: thermal balance modeling on the basis of a semi-empirical radiation model, and optimal iterative learning controller design on the basis of a linear state space model. First, we found through steady state radiation modeling that the fourth power of wafer temperatures, lamp powers, and the fourth power of chamber wall temperature are related by an emissivity-independent linear equation. Next, for control of the MIMO system, a state space modeland LQG-based two-stage batch control technique was derived and employed to reduce the heavy computational demand in the original two-stage batch control technique. By accommodating the first result, a linear state space model for the controller design was identified between the lamp powers and the fourth power of wafer temperatures as inputs and outputs, respectively. The control system was applied to an experimental RTP equipment. As a consequence, great uniformity improvement could be attained over the entire time horizon compared to the original multi-loop PID control. In addition, controller implementation was standardized and facilitated by completely eliminating the tedious and lengthy control tuning trial.