• Clinical and Experimental Pediatrics
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• v.52 no.9
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• pp.1035-1037
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• 2009

Patent ductus arteriosus (PDA) is a common congenital heart defect. All PDAs, regardless of size or degree of symptoms, require occlusion. Transcatheter PDA occlusion features fewer complications than trans-thoracic closure. It is also more cost-effective and has an excellent occlusion rate. Therefore, transcatheter PDA occlusion is accepted as the standard treatment option for PDA. However, tubular-type PDAs are difficult to close with ordinary detachable coils or the Amplatzer Duct Occluder; thus, these lesions remain a challenge for transcatheter closure. We attempted to occlude a tubular-type PDA by using an oversized Amplatzer Vascular Plug, which allowed intraluminal packing of the ductus. By using this treatment method, PDA occlusion was achieved safely with an excellent final outcome. We suggest that this approach may be a good option for transcatheter closure of a tubular-type PDA.

• Clinical and Experimental Pediatrics
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• v.53 no.12
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• pp.1012-1017
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• 2010

Purpose: Transcatheter closure has become an effective therapy in most patients with patent ductus arteriosus (PDA). However, there are difficulties in transcatheter closure of PDA in small children. We reviewed clinical outcomes of transcatheter closure of PDA in children weighing less than 10 kg in a single center. Methods: Between January 2003 and December 2009, 314 patients with PDA underwent transcatheter closure in our institute. Among them, 115 weighed less than 10 kg. All of these patients underwent transcatheter closure of PDA using either COOK Detachable $Coil^{(R)}$, PFM Nit-$Occlud^{(R)}$, or Amplatzer duct $occluder^{(R)}$. A retrospective review of the treatment results and complications was performed. Results: The mean age of patients was $9.1{\pm}5.9$ months (median, 8 months), and mean weight was $7.6{\pm}1.8kg$ (median, 7.8 kg). The mean diameter of PDA was $3.2{\pm}1.4mm$ (median, 3 mm). Complete occlusion occurred in 113 patients (98%). One patient was sent to surgery because of a failed attempt at device closure, and another patient had a small residual shunt after device placement. The average mean length of hospital stay was $3.0{\pm}3.3$ days, and mean follow-up duration was $21.0{\pm}19.6$ months. There were no major complications in any of the patients. Conclusion: Transcatheter closure of PDA is considered safe and efficacious in infants weighing less than 10 kg. With sufficient experience and further effort, transcatheter closure of PDA can be accepted as the gold standard of treatment for this group of patients.

• Biomedical Science Letters
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• v.15 no.1
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• pp.17-23
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• 2009

The prevalence of patent foramen ovale (PFO) in healthy persons was estimated as about $10{\sim}25%$ and was up to 40% in patients with stroke. Transesophageal echocardiography (TEE) was considered to be the most sensitive method to detect PFO and was used as the gold standard. Transcranial doppler sonography (TCD) of the middle cerebral artery (MCA) during a contrast (saline bubble) injection has recently been proposed as an alternative detecting method for PFO. In this study, we would like to know the difference between TCD value and TEE value in subjects with cryptogenic ischemic stroke. We performed TCD and TEE tests to detect PFO on 64 patients (30 women and 34 men, mean age was 59.4 years) with cryptogenic ischemic stroke. PFO prevalence through TCD was 45.3% (29 of 64 patients) and the prevalence through TEE was 34.4% (22 of 64 patients). There was no statistical significance between PFO test and TCD test (P=0.206). But TCD had a sensitivity of 90.9% (20 of 22 patients), specificity of 78.6% (33 of 42 patients), positive predictive value of 69.0% (20 of 29 patients), and negative predictive value of 94.3% (33 of 35 patients). We concluded that TCD was a highly sensitive method for detecting a right-left shunt. Therefore, the non-invasive TCD test is a method more effective than the anti-invasive TEE test in the cost and evaluation of the existence or nonexistence of right to left shunt in addition to the screening method of the cerebrovascular disorder. Considering these points, TCD test could be recommended for patients with cryptogenic ischemic stroke as a useful and convenient method for screening of the existence or nonexistence of a right to left shunt caused by PFO.

• Advanced Industrial SCIence
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• v.2 no.4
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• pp.36-43
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• 2023

Native plants thrive naturally in specific areas without human intervention, offering significant potential as genetic resources and biotechnological assets across multiple sectors. To harness this potential, our focus was on analyzing domestic patents related to native plants, investigating their uses, effectiveness, active components, and extraction methods. Using the Korea Forest Service's National Standard Plant List, we gathered data from 988 patents on native plants and 430 patents on the use of native plant seeds. This comprehensive patent analysis aimed to reveal research patterns, technology levels, and emerging trends. The goal is to identify research trends, current technology levels, and provide insights for future patent applications involving native plants.

• Knowledge Management Research
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• v.19 no.2
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• pp.1-19
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• 2018

This study aims to identify the causal relationship among public technology transfer, technological performance, and research and development (R&D) productivity. Using the impulse-response function(IRF) of a panel vector autoregressive model (panel VAR), this study suggests the results of how long the factors such as technological performance (patent), public technology transfer, and R&D productivity takes and lasts if a one-unit shock of standard deviation occurs. As a result, first, the increase of public technology transfer activities has no power to increase the technology performance but improve the R&D productivity. If the public institute increases its technology transfer activities by one unit, the R&D productivity will increase within five years. Second, the impact of increasing technological performance on improvement of public technology transfer and R&D productivity is an insignificant. Third, the effect of R&D productivity on the public technology transfer creates a substantial reaction after a current time. Considering the structural relationships among public technology transfer, technological performance, and R&D productivity, if policy makers intend to construct the active R&D circumstance, technology suppliers should be motivated to run the active R&D mechanism because they achieve gains.

• Journal of Korean Society for Quality Management
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• v.48 no.1
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• pp.227-239
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• 2020

Purpose: The purpose of this study is to introduce the improving attorney system. It was confirmed by document writing that the staff in the field in Korea had the most difficulty in the Quality circle activities. The reform improving attorney is a quality expert at the Quality Secretariat and assists them in their documentation. Methods: Just as a patent attorney helps to get a patent, an improving attorney system helps document the improvement results of the field Quality circle and even standardizes the company. The process of introducing an improving attorney includes the declaration of an improving attorney are 11 levels of work. Results: An improving attorney was conducted in 600 organizations for 18 months. As a result of the comparison of the number of cases before and after the introduction of the improving attorney, the number of solution problem was lowered to 9 before 2016 and 8 in 2017, but after the introduction, it increased exponentially to 181 in 2018 and 162 in August 2019. In 2016 and 2017, only one standard was registered, but 64 standards were registered in 2018 and 71 in 2019. Conclusion: In this case, the improving attorney system was found to be helpful in activating the Quality circle. It is expected to revitalize Korea's Quality circle by spreading the improving attorney system to many companies.

• Proceedings of the Korean Society of Computer Information Conference
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• 2022.07a
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• pp.541-544
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• 2022

재난안전분야 연구 및 기술개발을 위한 현황분석 및 동향파악을 위해 연구개발활동의 주요 성과물인 특허정보의 활용은 매우 중요하다. 본 논문에서는 재난안전분야 국내 특허문헌을 대상으로 산업분야별 현황 및 특성을 분석하였다. 분석연구를 위해 재난안전분야 키워드를 포함하고 표준산업분류 매핑이 가능한 국내 특허정보를 식별하여 데이터셋으로 사용하였다. 분석 결과, 표준산업분류 체계의 산업분야 레벨별 특허 분포 현황 및 출원기관 분포 현황과 산업분야별 핵심 키워드가 자세히 파악되었다. 연구결과는 국가 재난대응을 위한 지능형 위기경보 체계 등을 개발하기 위한 정보 자원으로 활용이 기대되며, 향후 논문, 보고서를 통합한 포괄적인 재난안전분야 문헌 분석 연구가 필요하다.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.57 no.3
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• pp.253-261
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• 2024

This study investigated the digital color profiles corresponding to different maturity stages and levels of brown croaker Miichthys miiuy specimens collected from the Southern Sea of South Korea. Maturity stages were determined using photomicrographs of ovarian developmental phases, which were compared with digital color values. Brown croaker specimens ranged from 24 to 81 cm in standard length; mature ovaries were predominantly observed in specimens that exceed 40 cm in length. Monthly ovary color values were primarily concentrated in the 1st and 4th quadrants, with both a^* and b^* values falling within a range of ±15 centered on the origin. Similarly, the testes color values were predominantly situated in the 4th quadrant, with a^* and b^* values ranging from -5 to 15 and 10 to 14, respectively. While the color values of the mature and spawning stages overlapped within a narrow range, distinguishing between them required both the color value and monthly color value distribution to be considered. Thus, this study underscores the efficacy of digital color measurements for assessing brown croaker gonad maturity, and provides more quantitative insights compared to subjective visual assessments by humans.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2012.10a
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• pp.487-490
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• 2012

Under the situation of the world becoming a unified global economy, our country should make efforts to get standard patents as well as to take out essential patents in order to maintain the competitiveness against advanced country. In recent years, R&D related standardization is very important. Besides, R&D planning considering standardization becomes more important than ever before. Therefore, this treatise is designed to lay infrastructure on promoting international standardization through suggesting a effective standardization planning framework based on R&D planning and analyzing cases regarding R&D planning and standardization planning.

• Journal of Engineering Education Research
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• v.21 no.6
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• pp.81-89
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• 2018

Patents have been recognized as a core knowledge asset which are closely related with company's technological competitiveness. However, only a small portion of patents are actually contributing to the profit of the company. In addition, it costs a lot of money continuously to maintain the patent rights regardless of their values. Thus, effective methodologies are required to create patents with high values. It is examined what kind of differences exist between high value patents and the others in the use of TRIZ methodologies. For the purpose, we analyzed the US granted patents of Samsung Electronics. The analysis shows that there is no significant difference in the use of inventive principles, but high value patents utilize 'separation by condition' the most where as the others 'separation by space' the most frequently in the use of separation principles. In the use of standard solutions, high value patents use the 'class 2' principles frequently than the others.