• Computers and Concrete
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• 제13권1호
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• pp.117-133
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• 2014

This study presents a rapid method for determining the steady state migration coefficient of concrete by measuring the electric current. This study determines the steady state chloride migration coefficient using the accelerated chloride migration test (ACMT). There are two stages to obtain the chloride migration coefficient. The first stage, the steady-state condition was obtained from the initial electric current at the beginning of ACMT. The second stage, the average electrical current in the steady state condition was used to determine the steady state chloride migration coefficient. The chloride migration coefficient can be determined from the average steady state current to avoid sampling and analyzing chlorides during the ACMT.

• 대한지리학회지
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• 제49권5호
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• pp.728-746
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• 2014

이 연구는 젊은 연령집단의 선별적 이동 및 세대에 걸쳐 진행되는 단계적 이동이 농촌과 도시의 출산력 변화와 지역의 인구성장에 파급되는 과정을 시계열적으로 분석하는 것이 목적이며, 전라북도 14개 시군이 사례지역이다. 분석에 활용된 자료는 1970 1990 2010년 20-34세 연령집단의 지역 간 인구이동 O-D 행렬과 같은 기간의 20-34세 연령집단과 가임 여성인구 분포 및 출생 사망의 동태자료이다. 분석 결과, 첫째 각 시점의 젊은 연령집단은 큰 규모로 출생지에서 이출하는 선별적 이동을 했다. 둘째 세대별로는 앞선 세대는 과거 전라북도 농촌에서 도시로, 뒤따르는 세대는 현재 전라북도 도시들에서 수도권으로 이동하는 단계적 이동이 존재했다. 셋째 젊은 연령집단의 선별적 이출은 출산 가임인구 축소, 저출산과 고령화 그리고 자연적 인구감소라는 과정을 수반되는데, 단계적 이동에 따라 과거 농촌에서 이러한 과정이 진행되었고, 현재는 전라북도 도시지역에서도 진행되고 있다. 실제로 전라북도 대부분 군 지역은 1980년대 후반부터 연간 사망자수가 출생아수를 상회하는 자연적 인구감소가 나타났고, 2000년대 초반에는 도시 지역에서도 이 같은 현상이 확인된다. 따라서 단계적 이동은 비수도권 중소도시 인구성장을 결정짓는 주요한 원인이며, 결과적으로 정주계층을 따라 단계적 과소화로 이어지고 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.6929-6934
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• 2015

Background: Real life management of hepatocellular carcinoma occasionally deviates from guidelines for recommended therapy. Aims: To evaluate how frequent this deviation happens in our center and assess its impact on outcome. Materials and Methods: The treatment of 770 patients (87% males, mean age 57.8 years) was analyzed and the effect of deviation on outcome over 36 months was examined. Results: Of Barcelona Clinic liver cancer stages 0 and A patients, 65.8% received resection, ablation, liver transplantation or transarterial chemoembolisation for unresectable tumors more than 5 cm in diameter, and 34.2% received treatment recommended for later stages. Of stage B patients, 62.2% received recommended therapy, 34.3% of patients received supportive therapy or sorafenib and 3.5% received upward treatment stage migration. Among stage C patients, 7.6% received sorafenib, and most (79.2%) were given supportive care. Deviation from recommended therapy occurred in 34.2%, 37.7%, and 92.4% in stages 0-A, B and C. Survival of stage 0-A patients who received downwards treatment stage migration was lower than those who received recommended treatment (p <0.001). Upward treatment stage migration in stages B, C and D did not improve survival compared to those who received recommended treatment. Conclusions: Deviation from recommended therapy had a negative impact on survival in Barcelona Clinic liver cancer stage A patients.

• Animal cells and systems
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• 제1권2호
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• pp.329-335
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• 1997

The final pattern of the skeletal muscle of a vertebrate depends on the position-specific behavior of the muscle precursor cells during early developmental process and the abdominal muscle is made of cells which migrate a relatively long distance from their original tissue, myotome of dorsal mesoderm. We report the spatia-temporal migration pattern of abdominal muscle in Xenopus laevis by in situ hybridization and immunohistological studies. Shortly after hatching tadpole stage (stage 31/32), a group of myotomal cells detaches from the lower tip of the second somite and migrates ventrally to the lower position of abdomen. At stage 34/35, a second cell group migrates away from the third somite. Total 7 myotomal cell groups migrate ventrally one by one from the second to eighth myotome along their own pathways through the cell free space located between epidermis and subepidermal layer of the abdomen. During migration, the sizes of the cell groups (abdominal muscle anlagens) are increased to several tens fold. Around stage 40 all the abdominal muscle anlagens reaches their final positions and are interconnected side by side rostrocaudally. They are also connected to other types of muscles, forming a large multisegmented abdominal muscle. Heat shock study suggests that the disruption of segmentation of somites does not block the detachment of abdominal muscle anlagen, though the treatment gave stage- and dosagedependent effects on the migration speed.

• 대한지리학회지
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• 제49권4호
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• pp.525-545
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• 2014

이 연구는 전라북도를 사례로 부모-자녀 세대에 걸쳐 진행되는 단계적 이동이 비수도권 중소도시 인구 성장에 미치는 영향을 탐색하는 것이다. 이를 위해 부모 세대를 베이비 부머, 자녀 세대는 에코 부머로 설정하였고, 거시자료를 이용하여 이들의 출생, 분포 변화와 선별적 이동과정을 추적하였다. 그리고 단계적 이동을 분석하기 위해 전라북도 시부, 군부 및 타 시도를 각각 출발지와 도착지로 설정하였다. 연구의 주요 결과는 다음과 같다. 첫째, 베이비 부머 세대는 전라북도 시부보다 군부에서 출생아수가 약 7배 이상 많았던 것으로 추정된다. 둘째, 부모 세대가 성장하여 선별적 이동을 진행할 때, 전라북도 시부와 군부 모두에서 타 시도로, 특히 수도권과 대도시로 이출이 탁월하게 나타났다. 하지만 전라북도 군부 출생자 상당수는 시부로도 이동하였고, 그 이동량은 전라북도 시부에서 타 시도로 이출한 양을 채워주는 수준이었다. 셋째, 자녀 세대에서는 전라북도 군부보다 시부에서의 출생아수가 더 많은데, 이것은 부모 세대가 농촌에서 도시로 단계적 이동을 했던 것에 기인한다. 넷째, 자녀 세대의 20대 연령 선별적 이동에서도 부모 세대와 유사하게 수도권과 대도시 등으로 이출이 압도적인 비율을 차지하였다. 그러나 전라북도 군부에서 시부로 이입되는 이동량이 부모 세대에 비해 현저하게 줄어들었고, 결과적으로 전라북도 도시들에서 음(-)의 순이동자 수가 해마다 누적되고 있다. 마지막으로 단계적 이동은 인구의 사회적 성장요인이자 동시에 이동자 생애경로의 결혼, 출산, 양육 등과 결부되어 자연적 성장요인에도 영향을 주었다. 따라서 부모-자녀 세대에 걸쳐 진행되는 단계적 이동은 비수도권 중소도시 인구의 증가와 감소를 결정짓는 주요한 요인이라고 할 수 있을 것이다.

• 한국인구학
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• 제12권1호
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• pp.30-42
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• 1989

This study develops a model of migration decision-making process, with identifying macrolevel and microlevel factors affecting the process. The model includes some sequential stages : to be dissatisfied with current residential area, intend to move, collect information about alternative destinations, select destination, decide to move, and make actual migration. The macrolevel factors included in the model are environmental, socioeconomic, cultural, and demographic characteristics of the current residence and alternative destinations. The microlevel factors are psychological, socioeconomic, and demographic characteristics of the individual. The effects of the macrolevel and microlevel factors on each stage of migration decision-making process are identified from the previous studies on migration. This study has both theoretical and practical implications. The theoretical contribution will be in the area of integrating the ecological and the individual level perspectives of migration by identifying the macrolevel and microlevel effects on migration decision-making process. This study also has implications for theoretical frameworks guiding empirical analysis of migration behavior of the individuals, and for policies aimed at redistributing population.

• Advances in concrete construction
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• 제1권3호
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• pp.239-252
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• 2013

Mortar microstructure is considered as a three-phase composite material, which is cement paste, fine aggregate and interfacial transition zone. Interfacial transition zone is the weakest link between the cement paste and fine aggregate, so it has a significant role to determine the properties of cementitious composites. In this study, specimens (w/c = 0.35, 0.45, 0.55) with various volume fractions of fine aggregate ($V_f$ = 0, 0.1, 0.2, 0.3 and 0.4) were cast and tested. To predict the equivalent migration coefficient ($M_e$) and migration coefficient of interfacial transition zone ($M_{itz}$), double-inclusion method and Mori-Tanaka theory were used to estimate. There are two stages to estimate and calculate the thickness of interfacial transition zone (h) and migration coefficient of interfacial transition zone ($M_{itz}$). The first stage, the data of experimental chloride ion migration coefficient ($M_s$) was used to calculate the equivalent migration coefficient of fine aggregate with interfacial transition zone ($M_e$) by Mori-Tanaka theory. The second stage, the thickness of interfacial transition zone (h) and migration coefficient of interfacial transition zone ($M_{itz}$) was calculated by Hori and Nemat-Nasser's double inclusion model. Between the theoretical and experimental data a comparison was conducted to investigate the behavior of interfacial transition zone in mortar and the effect of interfacial transition zone on the chloride migration coefficient, the results indicated that the numerical simulations is derived to the $M_{itz}/M_m$ ratio is 2.11~8.28. Additionally, thickness of interfacial transition zone is predicted from $10{\mu}m$, 60 to $80{\mu}m$, 70 to $100{\mu}m$ and 90 to $130{\mu}m$ for SM30, M35, M45 and M55, respectively.

• 대한종양외과학회지
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• 제14권2호
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• pp.120-127
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• 2018

Purpose: The purpose of this study was to determine the immunologic role of lymph node (LN) and stage migration by assessing LN count and metastatic LN count. Methods: A total of 2,117 patients with gastric adenocarcinoma located in the body and antrum who underwent distal/subtotal gastrectomy with D2 LN dissection between January 1, 1998 and December 31, 2008 were enrolled. LN count and number of metastases were determined in the N1 tier (area of D1 dissection) and N2 tier (area of D2 dissection). The lower and upper quartiles of LN counts in the same pN stage were grouped to compare the prognosis and LN positivity according to the LN tier. Results: Stage migration from N1 tier to N2 tier occurred in 3.2% of cases. The 5-year disease-specific survival rates of the upper and lower LN count groups within the N1 tier were 91.0% and 86.7% (P=0.01), respectively. LN positivity in the N2 tier of the lower LN count group was higher than that of the upper LN count group (14.1% vs. 8.2%, P<0.01). Stage migration in the N2 tier of the lower LN count group was also higher than that of the upper LN count group (4.6% vs. 1.8%, P<0.01). Conclusion: The lower LN count group had a decreased survival rate compared to that of the upper LN count group, suggesting that perigastric LN has an immunological defense role in weakening the disseminating power of metastatic tumor cells, as indicated by the LN count.

• 생태와환경
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• 제38권spc호
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• pp.27-30
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• 2005

Diel vertical migration (DVM) and horizontal distribution of Chaoborus flavicans larvae were studied in Lake Fukami-ike (maximum depth 7.75 m, Central Japan). The larvae showed a clear migration in the 4 ${\sim}$ 7 m layer during the day and throughout the water column at night. It should be noted that, while old instar distributed throughout the column during the night. Young instar was found only in the 1 ${\sim}$ 4 m layer. An examination of horizontal distribution revealed that larval stage was clearly related with the depth. It suggests that Chaoborus appear to exist in the deeper area during the larval stage.

• 한국발생생물학회지:발생과생식
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• 제2권1호
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• pp.45-52
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• 1998

강화인자 검출법을 이용 X염색체에 P[1ArB]이 형질전환되어 극세포 및 경게세포에서 표시유전자 lacZ를 발현하는 노랑초파리 (EDL 149)를 이용하여 난자형성과정 동안의 경계새포의 분화 및 이동을 조사하였다. 경계세포는 9기 난포의 선단에 위치한 난포 세포로부터 분화하여 9기와 10기에 이동하는 것을 확인하였다. 난소내 \beta -galactosidase의 활성은 우화 후 처음 4일간 급격히 증가하는 것을 확인하였으며 이 시기는 난포 내에서 경계세포가 분화하는 시기와 일치하였다. EDL149의 P[1ArB]삽입의 동형접합체의 난포 내에서 일부 경계세포의 불완전한 이동 또는 지연이 관찰되었다. 감수분열을 진행중인 정소내 세포 및 더듬이에서 확인된 lacZ 유전자의 발현양상은 P[1ArB]의 삽입부위가 난소특이 유전자부위가 아니지만 경계세포 이동의 조절에 역할을 하는 유전자임을 암시한다. 이 형질전환초파리 및 삽입위치 부근의 유전자는 발생중 진행되는 세포이동의 연구에 좋은 모델로 생각된다.