• 한국초지조사료학회지
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• 제19권4호
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• pp.309-316
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• 1999

풋베기용 콩의 개량을 목적으로 진품 I, II호, 검정 I, II호, 황금, 석량붓콩, 장엽, 검정올콩, 보광, 만리 등 10개의 대두 품종을 재배하여 품종별 특성과 생산수량을 호숙기를 기준으로 비교하였다. 10개 품종 중 초고가 큰 품정은 검정 I(118cm), 검정 II호(114cm)와 진품 I호(114cm)와 진품 I호(114cm)이었다. 또한 생초수량은 진품 I, II호, 검정콩 II호가 각각 ha당 23,841kg, 23,499kg, 22,815kg, 건물수량은 각각 ha당 5,531kg, 5,173kg, 5,236kg으로 다른 품종에 비해 많았다. 호숙기의 대두 식물체의 잎과 줄기의 구성비율은 검정올콩과 보광을 제외하고, 모든 품종에서 잎이 많았으며 엽경비율이 가장 큰 품종은 만리(2.1), 진품 I호(1.9), 황금(1.9)였다. 대두 식물체의 건물율은 호숙기에서 조생종인 석량붓콩과 검정올콩을 제외하면 22~23.4% 사이에 있었다. 이상의 결과를 종합할 때 키가 크고, 수량이 많으며, 잎이 풋베기용으로 적합한 품종은 진품 I, 검정 II이었다.

• 자원환경지질
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• 제27권3호
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• pp.219-229
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• 1994

The Sangra Pb-Zn deposit is located in the Gampo area. Most Cretaceous sedimentary rocks and Paleogene felsic intrusives in the study area have experienced intense propylitization. Such propylitization and Pb-Zn mineralization in ore veins are involved with the fluid having very low oxygen isotopic composition.Sulfurisotopic equilibrium temperature during the main Pb-Zn mineralization (late stage I) is calculated as $T=275^{\circ}{\sim}295^{\circ}C$. Oxygen and sulfur fugacity in late stage I fluid is estimated as $logfO_2=-34.4{\sim}-29.1$ and $logfS_2=-12.0{\sim}-8.2$ bars. It is inferred that the sulfur isotopic composition oflate stage I fluid was very high such as ${\delta}^{34}S_{{\Sigma}S}=+22.4{\sim}+22.5$‰ and the origin of sulfur was ocean water sulfate. Oxygen and hydrogen isotopic composition of water in ore-forming fluid was gradually increased and more abundantly affected by ocean water from early to late mineralization stage as follows; (late stage I) ${\delta}^{18}O_{H2O}=-7.2{\sim}-1.1$‰, ${\delta}D_{H2O}=-87{\sim}-84$‰, (stage II) ${\delta}^{18}O_{H2O}=-2.4{\sim}-0.8$‰, ${\delta}D_{H2O}=-39{\sim}-21$‰ (stage III) ${\delta}^{18}O_{H2O}=+0.7{\sim}+12.6$‰, ${\delta}D_{H_2O}=-49{\sim}-42$‰. The pH in ore-forming fluid was about 4.7 during late stage I and is thought to have been gradually decreased from late stage I to stage II mineralization.

• 자원환경지질
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• 제23권1호
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• pp.25-33
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• 1990

Gold-silver deposits of Deogheun and Beopjeon mines are composed of veins emplaced in Jurassic granite batholith. Based on ore structure and ore mineralogy, four distinct stages of mineral deposition are recognized in these ore deposits. Gold and silver minerals in Deogheun and Beopjeon-A ore deposits are precipitated in stage III and stage II, respectively. Mineral constituents of ores from these deposits are pyrite, sphalerite, arsenopyrite, pyrrhotite, chalcopyrite, galena, tetrahedrite, electrum, quartz and rhodochrosite. Cubanite, argentite and pyrargyrite occur only in Deogheun ore deposits. Ag content of electrum range from 42 to 66 atomic % in both ore deposits. Filling temperature of fluid inclusion from both ore deposits are as follows; stage I, $211-289^{\circ}$ ; stage II, $205-290^{\circ}$ ; stage III, $190-260^{\circ}$ ; stage IV, $136-222^{\circ}$ in Deogheun ore deposits. In Beopjeon-A ore deposits, stage I, $255-305^{\circ}$ ; stage II, $135-222^{\circ}$ ; stage III, $148-256^{\circ}$ ; stage IV, $103-134^{\circ}$. Salinities of fluid inclusions range from 1.6-8.5 wt. % equivalent NaCl in both ore deposits. Sulfur fugacities through stage II and III in Deogheun ore deposits inferred from data of mineral assemblage and fluid inclusion range from $10^{-11.0}-10^{-16.1}$1bars. Fluid pressure estimated from fluid inclusions which reveal boiling evidence range from 30-190 bars during mineralization in Deogheun ore deposits.

• Journal of Chest Surgery
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• 제24권1호
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• pp.72-82
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• 1991

From May 1978 to Sep. 1990, 106 patients who had been diagnosed as primary lung cancer and operated on at the Department of Thoracic & Cardiovascular Surgery, Han Yang University, were clinically evaluated. 1. The peak incidence of age was 5th decade of life[37.7%] and 6th decade[29.2%]. Male to female ratio was 3.8: l. 2. Most of symptoms were respiratory, which were cough, chest pain, hemoptysis, and asymptomatic cases were 2.9%. 3. Histopathologic classifications were squamous cell carcinoma[53.7%], adenocarcinoma [23.8%], bronchioloalveolar cell carcinoma[6.6%], undifferentiated large cell carcinoma[6.6%], small cell carcinoma[3.8%], adenosquamous carcinoma[3.8%] and others[1.8%]. 4. Methods of operation were pneumonectomy 49.1%[52cases], lobectomy 21%[22cases] bilobectomy[6cases], lobectomy with wedge resection[3cases], exploration 21.9%[23cases], and resectability was 78.3%. 5. Staging classifications were Stage I [22.6%], Stage II [11.3%], Stage IIIa[42.6%], Stage IIIb[21.7%] and Stage lV[1.6%]. Resectability by Stage; Stage I was 100%, II 100%, IIIa 84.4% and IIIb 30.4%. 6. Causes of most of inoperable cases were invasion of mediastinal structures and diffuse chest wall, and others were contralateral lymph node invasion and malignant pleural effusion. 7. Operative mortality was 6.7% which caused by arrhythmia, sepsis, pulmonary edema, and radiation pneumonitis. 8. On the long term follow up of the resectable cases, overall 1 year survival rate was 58.5 %, 2 year 39%, and 5 year 19.5%. Five year survival rate was 40% in Stage I, 25% in Stage II and 11.7% in Stage Illa. As for the method of operation, the higher 5 year survival rate was observed in lobectomies[33.3%] than in pneumonectomies[10.3%].

• Journal of Chest Surgery
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• 제29권1호
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• pp.43-51
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• 1996

인제대학교의과대학 부산 백병원 흉부외과학 교실에서는 1989년 3월 부터 1993년 10월까지 4년 7개월간 원발성 비소세포성 폐암으로 확진되고 수술받은 57례를 대상으로 관찰하였다. 성별은 남자 45명, 여자 12명 (M:F=3.8:1)이었고, 호발연령군은 50~59세 (45.6%), 60~69세 (35.1%)이였다. 대부분의 증상은 호흡기 계통으로 기침 59.6%, 흉통 42.1%, 혈담과 객혈 28.1% 그리고 무증상이 7%였다. 술전 진단상 양성율은 객담 세포진 검사 11%, 기관지 세척 세포검사와 생검은 각각 50%, 73% 였고 컴퓨터 단층 촬영술하 경피천자 생검은 836% 였다. 병리 조직학적 분류로 편평상피세포암이 56.1%, 선암이 22.8%, 기관지폐포암 7%, 혼합형 10.5%, 미분화 거대세포암 1.8%, 기타 1.8%이였다. 수술 방법은 일측전폐 절제술이 35.1%, 엽절제술 38.6%, 이 엽절제술 3.5%, 부분 절제술 7%, 개흥술 15.8%로 절제율은 84.2%였다. 병기별 분류는 병기 I이 28.1%, II가 22.8%, IIIa가 31.6%, IIIb가 17.5%였고, 절제율은 병기 I과 II가 100%, IIIa가 88.9%, 그리고 IIIb가 30%였다. 술후 합병증은 11례 (19.3%)에서 발생하였으며 수술로 인한 조기 사망은 없었다. 절제술을 시\ulcorner한 례에서 생존율은 1년, 2년, 5년에서 각각 87.0%, 61.6%, 44.9% 이었고, 병기별 3년 생존율은 병기 I이 75.8%, II가 16.9%, IIIa가 60.9%, IIIb가 50%였다.

• 한국패류학회지
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• 제30권4호
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• pp.311-319
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• 2014

본 연구의 결과인 수온조절에 의한 큰가리비의 생식소 발달을 조사한 결과, 암컷 샌식소지수 (GSI) 경우 1월에 실험구 I가 $9.12{\pm}2.9$, 2월에 $14.89{\pm}2.9$, 3월에 $21.3{\pm}1.4$로 지속적으로 상승하였다. 2월에 실험구 I, II, III과는 유의차가 없었으나 (P > 0.05), 실험구와 대조구와는 유의가 있었다 (P < 0.05). 실험구 I은 지속적으로 성숙하여 산란 가능한 범위로 성성숙 및 산란하여 가장 좋은 결과를 보였으며 타 시험구와 유의하게 높았다 (P < 0.05). 조직학적 관찰을 통해 생식소 발달을 조사한 결과, 1월에는 모든 실험구의 큰가리비 난소가 성장기 (growing stage) 단계로 확인되었다. 2월의 대조규 난소는 성장후기 단계였으며, 실험구 I, II 및 III은 모두 성숙기(mature stage)로 확인되었다. 어미의 실내 성성숙 유도를 위하여 수온 $12^{\circ}C$를 유지한 결과, 11월에 생식소 지수 및 생식소 중량은 각각 $4.4{\pm}0.88$, 2.8 g 이였으나 1월에 $15.1{\pm}2.8$, 11.7 g, 2월에 $21.7{\pm}5.4$, 19.4 g으로 급격히 생식소지수가 증가되어 2월에 방란, 방정이 가능하여 자연 산란군보다 2-3개월의 조기 산란 유도가 가능하였다. 수온 약 $16^{\circ}C$에서 수정란은 나선상 난할 (spiral cleavage)을 시작하여 낭배기(gastrula stage)를 거쳐 약 1.5일 후에는 담륜자 (trochophore) 유생이 되어 부상하여 유영하였다. 약 10일 후에는 초기원각 (prodissoconch shell)을 형성하여 각정기 유생기 (umbo stage larva)가 시작되며 각정 (umbones)이 형성되었다. 이후 각정기 유생은 성숙하여 수정 후 20-23일 후에는 팜사나 경심망 등의 기질에 부착하여 부착치패가 되어 조기 종묘 생산이 가능하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제45권2호
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• pp.83-90
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• 2019

Objectives: This study evaluated the predictive factors for survival of patients with oral squamous cell carcinoma (OSCC) and investigated the overall and disease-specific survival (DSS) outcomes. Materials and Methods: A total of 67 consecutive patients who underwent surgery for OSCC from January 2006 to November 2014 were included in this study. Patients were classified according to age, sex, pTNM stages, primary sites, smoking and alcohol drinking habits, depth of invasion, perineural and lymphovascular invasion, cell differentiation and postoperative radiotherapy. Kaplan-Meier methods were used to estimate the survival categorized by patient groups. Cox regression methods were used to investigate the main independent predictors of survival. Results: Nineteen patients died of OSCC during follow-up periods. Another five patients died of other diseases including lung adenocarcinoma (n=1), cerebral infarction (n=1), general weakness (n=2), and pneumonia (n=1). The tongue (n=16) was the most common site for primary origin, followed by buccal mucosa (n=15), mandibular gingiva (n=15), maxillary gingiva (n=9), floor of mouth (n=9), retromolar trigone (n=2), and palate (n=1). Eleven patients had pTNM stage I disease, followed by stage II (n=22) and stage IV (n=34). No patients had pTNM stage III disease in this study. The overall survival of all patients was 64.2% and the DSS was 71.6%. DSS of patients with stage I and II disease was 100%. Stepwise Cox regression showed the two predictors for DSS were pTNM stage (P<0.0001, odds ratio=19.633) and presence of metastatic lymph nodes (P=0.0004, odds ratio=0.1039). Conclusion: OSCC has been associated with poor prognosis; however, there were improved survival outcomes compared with past studies. Advanced-stage disease and presence of metastatic lymph nodes were associated with poorer survival compared with early-stage OSCC and absence of neck node metastasis. Stage I and II OSCC were associated with excellent survival results in this study.

• Journal of Chest Surgery
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• 제20권2호
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• pp.328-341
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• 1987

We reviewed 147 cases of primary carcinoma of the lung between January 1975 and December 1986 at the Thoracic and Cardiovascular Department, Yonsei university College of Medicine, Seoul, Korea. There were 116 males and 31 females with 93.72% ranging in age from 40 to 69 years. The mean age was 61.01 years. To 69 years of age with 61.01 years of mean age. There were 92 [62.59%] cases of squamous cell carcinoma, 29 [19.73%] cases of adenocarcinoma, 8 [5.44%] cases of undifferentiated large cell carcinoma, 8 [5.44%] cases of undifferentiated small cell carcinoma and 10 [6.8%] cases of bronchoalveolar cell carcinoma. 50 [34.01%] patients in stage I and 49 [33.26%] patients in stage II underwent pneumonectomies and lobectomies with a 67.27% rate of resection, where as only 49.12% of stage III patients were resected. Also 7 [30.43%] of the 23 stage IV cases were surgically resected and confirmed stage IV after surgical resection. The actuarial survival rate according to classification are as follows. The one and 3 year survival rate of the patients in stage I were 96% and 84% respectively. The one and `3 year survival rate of the patients in stage II were 100% and 66.6%, whereas the one and 3 year survival rate of the patients in stage III, T3 were 78.57% and 69.84%. The survival rates of patients in stage I, II, III T3 were better than those of the other stages. There were significant differences in observed survival for patients with stage II as compared with the patients with stage Ill, T3. [p=0.0005]. An aggressive surgical approach still offered the greatest chance for long-term survival even in stage Ill, T3. The survival rate in patients with resectable cases including stage III, T3 might be improved with an aggressive surgical approach. The one and 3 year survival rates of patients in stage III, N2 were 56.67% and 43.7 I%. The one and 3 year survival rates of patients in stage IV were 21.43% and 3.57%. Patients in stage III, N2 or IV had markedly decreased survival rates. When the carcinoma cell type was the basis for the determination of rate of survival, the result were as follows; The one, 3 and 5 year survival rates of squamous cell carcinoma were 78.33%, 60.19%, and 57.32%, and the one and 3 year survival rates of adenocarcinoma were 55.56% and 44.49%. The survival rates of large cell carcinoma were 66.67%, and 44.45%, at one, three and five years respectively. The one and 3 year survival rates of bronchoalveolar cell carcinoma were 71.43% and 47.62%, the one, 3 and 5 year survival rates of small cell carcinoma were 40%, 20% and 20%. The survival rate of squamous cell carcinoma was better than that of other cell carcinomas, the survival rate of small cell carcinoma was the worst. The operative mortality rate was 1.36%. There were 10 cases of post-operative complications including 2 cases of bleeding which required further surgery, 2 cases of wound infection, and 4 cases of empyema thoracis. The length of survival of three of the empyema thoracis cases was 16, 98 and 108 months respectively, Four male patients all older than 47 years survived more than 9 years, post surgery, although one developed empyema thoracis. These four cases were initially classified as 2 cases of stage I and one each of stage II and stage III, T3. We have concluded that the survival rates of patients in stages I, II and III, T3 were improved after complete surgical resection.

• 자원환경지질
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• 제30권3호
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• pp.197-207
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• 1997

Rocks in the Cheongsong mine area consist of Precambrian gneiss, Cretaceous sedimentry rocks and late Cretaceous quartz porphyry. The Cheongsong deposit is composed of many hydrothermal quartz veins of strikes $N30^{\circ}{\sim}60^{\circ}W$, dips $60{\sim}85^{\circ}E$ which fill WNW fault system. Pyrite and hematite occur within transparent quartz near margins of early stage II, and milky quartz of middle stage II coexists with sphalerite, chalcopyrite and galena coexisting with Cu-Pb-Bi minerals in center part of stage II quartz veins. Stage III calcite vein filled cracks or fractures of earlier quartz veins contains native copper and chalcopyrite. Supergene minerals are chalcocite, covellite, malanchite and chrysocolla. Alteration minerals are sericite, chlorite, argillite, epitode and pyrite. Ranges of salinities and homogenization temperatures for fluid inclusions in the individual periods of stage II are: 3.7 to 7.8 wt.% eq. NaCl and 200 to $380^{\circ}C$ in transparent quartz of early stage II; 0.7 to 6.4 wt.% eq. NaCl and 200 to $320^{\circ}C$ in milky quartz of middle stage II; 0.0 to 0.9 wt.% eq. NaCl and 250 to $320^{\circ}C$ in calcite of late stage II. Those of stage III calcite range about 0 wt.% eq. NaCl, and from 140 to $260^{\circ}C$, respectively. The relationship between salinities and temperatures shows decrease tendency with paragenetic time from stage II to III. The ${\delta}^{18}O_{H_2O}$ value is 0.5‰ in stage I, range from 0.5 to -0.4‰ in stage II, and from -3.2 to -3.7‰ in stage III. Calcite in the stage II and stage III has ${\delta}^{13}C$ values of -5.0‰ and -4.5 to -4.9‰, respectively. There is a decrease in sulfur fugacity values with paragenetic time of stage II, from $10^{-6.3}$ atm for early mineralization, to $10^{-6.5}$ atm for middle stage, to $10^{-8.0}$ atm for late mineralization of stage II. The results of stable isotope and fluid inclusion indicate that ore fluids reacted with meteoric water and wall rock in the Cheongsong hydrothermal system.

• Radiation Oncology Journal
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• 제15권2호
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• pp.129-136
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• 1997

목적 : 본병원에서 방사선 단독치료를 받은 자궁경부암 환자의 생존율 및 재발 양상을 분석 하고 이에대한 결과를 비교 분석함으로서 치료방법에 대한 평가를 하고자 하였다. 대상 및 방법 : 1987년 5월부터 1991년 12월까지 자궁경부암병기(FIGO) IB, II A, II B 로 근치목적의 방사선치료를 완료한 220명의 환자를 대상으로 후향적 분석을 시행하였다. 이중 병기 IB환자는 1995년에 개정된 FIGO 분류법에 의해서 분석당시 IB1과 IB2로 재분류를 시행하였다. 방사선치료는 외부방사선치료와 강내조사를 병용하였으며 방사선치료 후 6개월에서 국소종양의 치유여부를 판정하였다. 추적기간은 3개월에서 115개월까지 였으며 평균 62개월이었고 추적율은 $93.6\%$(206/220) 였다. 결과 : 병기별 5년 생존율은 IB1(N=50), IB2(N=15), II A(N=58), II B(N=97)에서 각각 $94\%,\;87\%,\;69\%,\;56\%$였다. 생존과 관계있는 예후인자로는 병기(p=0.00), 진단시 혈색소치(p=0.00), 진단시 종양표지자 수치(p=0.02), 종양의 크기(0.00), 골반단층촬영에서의 임파선전이(p=0.04) 등이 통계적인 유의수준을 보였으나 다요인 분석에서는 병기만이 유일하게 통계적인 유의수준의 차이를 보였다. 판정이 가능한 214명의 방사선치료에 따른 국소종양제어율은 $81\%$였으며, 병기별로보면, IBI, IB2, II A, II B 각각 $100\%,\;86.7\%,\;84.5\%,\;68.1\%$의 결과를 보였다. 치료 후 재발율은 $15.5\%$(27/174)였으며, 병기별로 보면 IBI, IB2, II A, II B 각각 $8\%,\;0\%,\;22.4\%,\;19.4\%$였다. 결론 :촌기 자궁경부암 환자의 치료결과는 이미 보고되어 있는 다른 결과와 비교시 비슷한 수준을 보이나 진행된 II B 환자에서는 낮은 생존율의 결과를 보이고 있으며 이에대한 원인분석과 치료방법의 개선이 필요하다 하겠다.