• Title/Summary/Keyword: Stage I and II

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Physiological and Biochemical Studies on the Adult Hemolymph proteins in Lepidoptera. 1. Appearance of Adult Specific Proteins in the Hemolymph of the Silkworm, Bombyx mori. (인시목 곤충의 성충체액단자질에 관한 생리성화학적 연구 1. 가잠의 성충특이체액단자질의 검출)

  • 성주일;문재유
    • Journal of Sericultural and Entomological Science
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    • v.30 no.1
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    • pp.20-24
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    • 1988
  • Adult specific proteins, referred to as ASP-I(adult specific protein of slow mobility) and ASP-II(adult specific protein of slow mobility) at the pharate adult stage of the silkworm, Bombyx mori, were detected by polyacrylamide gel electrophoresis. The adult specific proteins (ASP-I and ASP-II) were defined as a kind of adult hemolymph proteins without sex specificity, and the was no variation in the respective electrophoretic mobility of ASP-I and of ASP-II among the forty-one silkworm varieties. tested.

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Genetic Environment of the Samsung Gold-Silver Deposit, Republic of Korea: Ore Minerals, Fluid Inclusion and Stable Isotope Studies (삼성 금-은광상의 생성환경: 광석광물, 유체포유물 및 안정동위원소 연구)

  • Yoo, Bong-Chul;Lee, Gill-Jae;Koh, Sang-Mo;You, Byoung-Woon
    • Economic and Environmental Geology
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    • v.43 no.5
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    • pp.443-453
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    • 2010
  • The Samsung gold-silver deposit consists of quartz veins that fill along the fault zone within Cretaceous shale and sandstone. Mineralization is occurred within fault-breccia zones and can be divided into two stages. Stage I is main ore mineralization and stage II is barren. Stage I is associated with wall-rock alteration minerals(sericite, pyrite, chlorite, quartz), rutile, base-metal sulfides(pyrrhotite, pyrite, sphalerite, chalcopyrite, galena), and electrum. Stage II occur quartz, calcite and pyrite. Fluid inclusion data indicate that homogenization temperatures and salinities of stage I range from 145 to $309^{\circ}C$ and from 0.4 to 12.4 wt.% NaCl, respectively. It suggests that hydrothermal fluids were cooled and diluted with the mixing of meteoric water. The main deposition of base-metal sulfides and electrum occurred as a result of cooling and dilution at temperature between $200^{\circ}C$ and $300^{\circ}C$. Sulfur(9.3~10.8‰) isotope composition indicates that ore sulfur was mainly derived from a magmatic source as well as the host rocks. The calculated oxygen[-2.3~0.9‰(quartz: 0.3‰, 0.9‰, calcite: -2.3‰)] and hydrogen[-86~-76‰(quartz: -86‰, -82‰, calcite: -76‰)] isotope compositions indicate that hydrothermal fluids may be meteoric origin with some degree of mixing of another meteoric water for paragenetic time.

A STUDY ON THE EXPRESSION OF TYPE I AND TYPE II COLLAGEN GENES AND PROTEINS IN THE DEVELOPING HUMAN MANDIBLE

  • Kook, Yoon-Ah;Kim, Sang-Cheol;Kim, Eun-Cheol
    • The korean journal of orthodontics
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    • v.25 no.6 s.53
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    • pp.723-731
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    • 1995
  • Type I and type II collagens are considered the major collagens of bone and cartilage respectively. Monitoring the patterns of those gene and protein expressions during development will provide a basis for the understanding of the normal and abnormal growths. This study was undertaken to investigate the expression of collagen genes and proteins involved in the developing human mandible. Fifty embryos and fetuses were studied with Alcian blue-PAS, Masson's Trichrome, reverse transcription polymerase chain reaction (RT-PCR), Western blot analysis, and Southern blot analysis. Our results showed that $pro-{\alpha}1(II)$ collagen gene expression begins in the 5th week. Type II collagen is synthesized in mesenchymal cells in advance: of overt chondrogenesis. The gene expression for type II collagen was highest during the appearance of Meckel's cartilage. There was a switch in collagen protein expression from type I to type II during the appearance stage of Meckel's cartilage. The distribution of the mRNA for type II collagen corresponded well with the pattern of type II collagen protein. The endochondral ossification was observed where there was direct replacement of cartilage by bone.

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Changes of Peroxidsse Isozyme Pattern and Formation of Cell Wall of Hairy Root Irlduced by Agrohacterium rhisogenes from Potato Tuber (감자(Solanum tuberosum. L) 괴경에 있어서 Agrobacterium rhizogenes에 의해 형질전환된 조직세포의 세포벽 형성과 peroxidase isozyme 양상의 변화)

  • 정현숙;김영희
    • KSBB Journal
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    • v.6 no.1
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    • pp.27-33
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    • 1991
  • Hairy root induced by A. rhizogenes from potato tuber (Solanm tuberosum L.) synthesized the agropine and mannopine which were demonstrated with paper electrophoresis. And the starch contents in hairy root were increased gradually following the developmental stage. But protein contents were decreased. The activity of ${\beta}-glucan$ synthetase II(GSII) which is related to the cell wall biosynthesis was stimulated in hairy root on the developmental stage. And chloropromazine did not influence the activity of GS II while verapamil inhibited about 60% of the activity GS II. Therefore, these results showed $Ca^{2+}$ to be effective factor in the cell wall formation. Isozyme pattern of peroxidase was investigated in the callus and hairy root induced from potato tuber.

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Seminiferous Epithelium Cycle and Developmental Stages of Spermatids in the Clethrionomys rufocanus

  • Lee, Jung-Hun
    • Development and Reproduction
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    • v.17 no.2
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    • pp.87-97
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    • 2013
  • The seminiferous epithelium cycle and developmental stages of spermatids in Clethrionomys rufocanus were observed under a light microscope. The seminiferous epithelium cycle was divided into 8 stages. Type Ad spermatogonia appeared through all stages. Type Ap, In, and B spermatogonia appeared in stages I, II, III, and IV. In the first meiosis prophase, the leptotene spermatocytes appeared from stage V, the zygotene spermatocytes in stages I, VI, VII, VIII, the pachytene spermatocytes from stages II to VI, the diplotene spermatocytes in stage VII. The meiotic figures and interkinesis spermatocytes were observed in stage VIII. Developing spermatids were subdivided into 10 steps, based on the morphological characteristics such as the acrosome formation changes in spermatozoa, nucleus, cytoplasm, and spermiation changes. The C. rufocanus spermatocytogenesis and spermiogenesis results displayed similar results with Apodemus agrarius coreae and A. speciosus peninsulae. Considering all the results, the spermatogenesis may be useful information to analyze the differentiation of spermatogenic cells and the breeding season.

The value of prophylactic cranial irradiation in limited-stage small cell lung cancer: should it always be recommended?

  • Koh, Minji;Song, Si Yeol;Jo, Ji Hwan;Park, Geumju;Park, Jae Won;Kim, Su Ssan;Choi, Eun Kyung
    • Radiation Oncology Journal
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    • v.37 no.3
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    • pp.156-165
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    • 2019
  • Purpose: Prophylactic cranial irradiation (PCI) is a standard treatment for limited-stage small cell lung cancer (LS-SCLC) showing a response to initial treatment, but many patients do not receive PCI due to comorbidities or refusal. This study aims to define the patient group for whom PCI can be omitted with minimal risk. Materials and Methods: Patients with LS-SCLC who underwent radiotherapy with curative aim at our institution between January 2004 and December 2015 were retrospectively reviewed. Patients who did not receive PCI were evaluated for brain metastasis-free survival (BMFS), progression-free survival (PFS), overall survival (OS), and prognostic factors for survival, and treatment outcomes were compared with a patient cohort who received PCI. Results: A total of 350 patients achieved a response following thoracic radiotherapy, and 190 of these patients did not receive PCI. Stage I-II and a complete response (CR) to initial therapy were good prognostic factors for BMFS and OS on univariate analysis. Patients with both stage I-II and a CR who declined PCI showed comparable 2-year BMFS to those who received PCI (92% vs. 89%). In patients who achieved CR, PCI did not significantly improve OS or PFS. Conclusion: There should be less concern about omitting PCI in patients with comorbidities if they have stage I-II or a CR, with brain metastasis control being comparable to those patients who receive PCI.

Gold-Silver Mineralizations in the Imgye District (임계지역(臨溪地域)의 금(金)-은(銀) 광화작용(鑛化作用))

  • Park, Hee-In;Hwang, Jeong;Huh, Soon-Do
    • Economic and Environmental Geology
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    • v.25 no.4
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    • pp.379-395
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    • 1992
  • The gold ore deposits of Nakcheon, Gongyeong and Dongmyeong mine in the Imgye district are E-W trending fissure filling veins emplaced in Precambrian Jungbongsan granite and sedimentary rocks of Cambrian Yangdeog group. The K-Ar age for vein alteration sericite and vein laced muscovite are 73 and 93 Ma, respectively. Vein structure and mineralogy indicate the three distinct depositional stages: I) basemetal sulfides and tin minerals, II) gold-basemeatl sulfides, III) gold-silver-basemetal sulfides. Major gold and silver ore minerals are electrum, native silver, pyrargyrite and argentite. Fluid inclusion data indicate that filling temperatures were from $350^{\circ}C$ to $190^{\circ}C$ through stage I, II and III. Salinities were in the range of 0.0~9.5 NaCl eq.wt.% and do not reveal any systematic trend. Intermittent boiling of ore fluid during stage I is indicated by fluid inclusions in quartz. Fluid pressure during stage I which is estimated from fluid inclusions showing boiling evidence range from 50 to 100 bars. Gold ore deposits of the Imgye district were formed under higher temperatures and lower sulfur fugacities compared with the Eunchi silver ore deposits about 8 Km apart from the Imgye district.

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Mineral Paragenesis and Chemical Composition of Sangeun Au-Ag Ore Vein, Korea (상은광산(常隱鑛山)의 Au-Ag 광맥(鑛脈)의 광물(鑛物) 공생(共生) 및 화학조성(化學組成))

  • Kim, Moon Young;Shin, Hong Ja;Kim, Jong Hwan
    • Economic and Environmental Geology
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    • v.24 no.4
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    • pp.347-361
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    • 1991
  • The Sangeun ore deposit is located in a volcanic belt within the Gyeongsang Basin in south western Korea. The ore deposit is of representative epithermal Au-Ag quartz vein type developed in lapilli tuff. This paper presents the mineralization with special emphasis on mineral zoning of the deposits. Principal points are summarized as follows: (1) Four stages of mineralization are recognized based on macrostructures. From ealier to later they are stage I(arsenopyrite-pyrite-quartz), stage II(Au-Ag bearing Pb-Zn-quartz), stage III(barren quartz), and stage IV(dickite-quartz). (2) Electrum principally occurs with arsenopyrite and galena in stage II, and has chemical compositions of 72.9-67.1 Ag atom %, and has Ag/Au ratio of 2.69-2.04. (3) Sphalerite varies in its FeS content according to the mineralization stages; 22.03-18.60 mole % FeS and 1.33-0.23 mole % MnS in stage IB, 16.11-8.64 mole % FeS and 1.33-0.23 mole % MnS in stage II. (4) Alteration zones of mineral assemblage, from the vein to the wall-rock, consist of sericite - quartz - pyrite, sericite - quartz - dickite, sericite - chlorite plagioclase respectively.

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Alteration of Biosynthesis and Secretion of Adrenal Catecholamines in Cycling Rat (발정주기 중 흰쥐 부신에서의 카테콜아민 합성과 분비 변화)

  • 이성호
    • Development and Reproduction
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    • v.6 no.2
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    • pp.105-110
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    • 2002
  • Numerous hormones are involved in the regulation of reproduction. Among them, estrogen and progesterone are the most important ovarian steroid hormones regulating female fertility. On the other hand, diverse stressors impede female receptivity and fertility. Since norepinephrine(NE) and epinephrine(E) are released from the adrenal during stress, it might play a role in stress-induced disruptions of fEmale reproductive parameters. The present study was performed to analyze the changes in adrenal catecholaminergic activities in cycling rats. The tissue content and secretion level of catecholamines were determined by high performance liquid chromatography coupled with electrochemical detector(HPLC-ECD). Adrenomedullary content of norepinephrine(NE) was increased on proestrus stage (59.47 $\pm$ 6.86 ug/gland), peaked on diestrus I stage(65.22 $\pm$ 5.99 ug/gland), and was nadir on diestrus II stage(41.63 $\pm$ 1.33 ug/gland). The highest E content was observed on proestrus stage(361.86 $\pm$ 15.58 ug/gland) while the lowest level was on diestrus II stage(285.58 $\pm$ 12.25 ug/gland). In addition to these observations, a significant reduction of the NE : E ratio was observed (1 : 4.81 on diestrus I vs 1 : 6.13~7.02 on other stages). In vitro secretion of adrenal NE and E was increased on proestrus stage, peaked on estrus stage, and decreased on diestrus II stage. Interestingly, the NE : E ratio in conditioned media was significantly increased on estrus stage (1 : 3.32 vs 1 : 2.34~2.65 on other stages. The biosynthesis of NE and E is mediated by tyrosine hydroxylase(TH) and phenylethanolamine-N-methyltransferase(PNMT) which acts conversion of tyrosine into DOPA and NE into E, respectively. These finding demonstrated that sex steroids, during setrous cycle, seem to be able to modify the adrenal catecholamines biosynthesis and secretion with stage-specific manner by modulation of the enzyme activities.

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Arthroscopic Debridement of the Knee Joint (슬관절의 관절경적 변연절제술)

  • Suh, Jeung Tak;Park, Byung Guk;Song, Jin Heon
    • Journal of the Korean Arthroscopy Society
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    • v.2 no.2
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    • pp.159-163
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    • 1998
  • We reviewed the cases of 35 knees of 34 patients who had arthroscopic debridement for degenerative osteoarthritis of the knee. The patients were followed up for an average of 29 months (range: 13 months to 45 months). The mean age of the patients at operation was 54 years (range: 44 years to 75 years). At the time of follow up, the patients were evaluated using the nine-point scale by Baumgaertner et al. We divided the knee into 4 stages according to the classification system by Jackson et al. Satisfactory results were achieved in 80%(stage I), 75%(stage II), 55.6%(stage III) and 25%(stage IV) of the patients. Arthroscopic debridement is of significant value in the earlier stages of degenerative osteoarthritis (stage I and II) for the symptom relief as a simple procedure with rare complication as well as in the later stages(stage III and IV) as a time buying procedure before the total knee arthroplasty.

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