• Maxillofacial Plastic and Reconstructive Surgery
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• v.22 no.2
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• pp.123-132
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• 2000

$TGF-{\beta}_1$ is a potent chemotactic factor for inflammatory cells and fibroblasts. It also stimulates the celluar source and components of extracellular matrix and the production of proteinase inhibitors. Collectively, these biologic activities lead to the accumulation and stabilization of the nascent matrix, which is vital to infection control. The objective of this study is to investigate production of $TGF-{\beta}$ in vitro fibroblast culture in the presence of Staphylococcus enterotoxin B(SEB) and/or lipopolysaccharide(LPS) and to elucidate the role of $TGF-{\beta}_1$ which may be responsible for infection control. The fibroblasts were originated from gingiva and facial dermis in 26 year-old male patient. In the presence of LPS($0.01{\mu}g$, $0.1{\mu}g$, $1.0{\mu}g$), SEB($0.01{\mu}g$, $0.l{\mu}g$, $1.0{\mu}g$) respectively, $cells(5{\times}10^3ml)$ were cultivated in vitro. At 1, 3, and 5 days after incubation, cells were counted. Also, $cells(2.5{\times}10^5ml)$ were cultivated in EMEM with LPS(0.01, 0.1 and $1.0{\mu}g$), SEB(0.01, 0.1 and $1.0{\mu}g$) respectively and $LPS(0.1{\mu}g)$ and $SEB(0.1{\mu}g)$ in combination for 24, 48, and 72 hours respectively. Culture supernatants were harvested at 1, 2, and 3 days after incubation period and triplicate culture supernatants were pooled and $TGF-{\beta}_1$ was assayed in duplicate. The results were as follows. 1. In gingival fibroblast induced with SEB and LPS respectively or in combination, the suppression of cell Proliferation occurred very significantly since 3 days after incubation, compared with the control and the production of $TGF-{\beta}_1$ occurred very significantly at 1 day after incubation, compared with the control. 2. In facial dermal fibroblast induced with SEB and LPS respectively or in combination, the suppression of cell proliferation occurred very significantly at 1 day after incubation, compared with the control. In SEB exposure, the production of $TGF-{\beta}_1$ was decreased very significantly at 1 day after incubation, compared with the control. However, in LPS, SEB and LPS exposure, the production of $TGF-{\beta}_1$ was increased very significantly at 1 day after incubation, compared with the control. In conclusion, the concentration of bacterial toxins and the incubation period correlated with cell proliferation and production of $TGF-{\beta}_1$ very significantly. The gingival and facial dermal fibroblasts have different phenotype each other The orchestrated understanding of fibroblast proliferation and $TGF-{\beta}_1$ production play an important part in host defense against the bacterial Infection and may prevent tissue necrosis such as necrotizing fasciitis and life-threatening syndrome such as multiple organ failure.

• Journal of Bio-Environment Control
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• v.31 no.4
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• pp.444-451
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• 2022

Recently, long-term cultivation is becoming more common with the increase in tomato hydroponics. In hydroponics, it is very important to supply an appropriate nutrient solution considering the nutrient and moisture requirements of crops, in terms of productivity, resource use, and environmental conservation. Since seasonal environmental changes appear severely in long-term cultivation, it is so critical to manage irrigation control considering these changes. Therefore, this study was carried out to investigate the effect of irrigation volume on growth and yield in tomato long-term cultivation using coir substrate. The irrigation volume was adjusted at 4 levels (high, medium high, medium low and low) by different irrigation frequency. Irrigation scheduling (frequency) was controlled based on solar radiation which measured by radiation sensor installed outside the greenhouse and performed whenever accumulated solar radiation energy reached set value. Set value of integrated solar radiation was changed by the growing season. The results revealed that the higher irrigation volume caused the higher drainage rate, which could prevent the EC of drainage from rising excessively. As the cultivation period elapsed, the EC of the drainage increased. And the lower irrigation volume supplied, the more the increase in EC of the drainage. Plant length was shorter in the low irrigation volume treatment compared to the other treatments. But irrigation volume did not affect the number of nodes and fruit clusters. The number of fruit settings was not significantly affected by the irrigation volume in general, but high irrigation volume significantly decreased fruit setting and yield of the 12-15th cluster developed during low temperature period. Blossom-end rot occurred early with a high incidence rate in the low irrigation volume treatment group. The highest weight fruits was obtained from the high irrigation treatment group, while the medium high treatment group had the highest total yield. As a result of the experiment, it could be confirmed the effect of irrigation amount on the nutrient and moisture stabilization in the root zone and yield, in addition to the importance of proper irrigation control when cultivating tomato plants hydroponically using coir substrate. Therefore, it is necessary to continue the research on this topic, as it is judged that the precise irrigation control algorithm based on root zone-information applied to the integrated environmental control system, will contribute to the improvement of crop productivity as well as the development of hydroponics control techniques.

• Composites Research
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• v.30 no.2
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• pp.102-107
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• 2017

The preceramic polymer can realize a variety of complex ceramic structures that can not be obtained by conventional ceramic processes. Polycarbosilane, which is a typical preceramic polymer, can control the molecular structure, molecular weight and molecular weight distribution for preparing complex morphology and microstructure of SiC ceramics, including SiC fiber. In this paper, synthesis and molecular structure control technique of polycarbosilane is explained. The silicon carbide fiber prepared by melt spinning, stabilization and heat treatment, and ceramic fiber composites technology made by PIP process are also discussed. In addition, we introduce an example of the development of a complex silicon carbide material such as a silicon carbide hollow fiber having a nanoporous structure.

• Journal of Bio-Environment Control
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• v.4 no.2
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• pp.188-194
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• 1995

This study was carried out to investigate the effect of NH$_4$H$_2$PO$_4$ on pH stabilization in deep flow culture system using tap water, and to determine the optimum range of NH$_4$H$_2$PO$_4$ in culture solution. The pH of tap water is 7.5. The higher the concentration of NH$_4$H$_2$PO$_4$ was, the more the pH of nutrient solution was decreased. In NH$_4$H$_2$PO$_4$ 4/3-5/3 me/$\ell$, the pH of nutrient solution was 6-7.5 during the experiment. The highest brix(%) was obtained in NH$_4$H$_2$PO$_4$ 5/3-6/3 me/$\ell$. Leaf length, leaf width and stem-base diameter were highest in NH$_4$H$_2$PO$_4$ 2/3 me/$\ell$. The L and b＊ values were highest and the a＊ value was lowest in NH$_4$H$_2$PO$_4$ 8/3 me/$\ell$. Toxicity symptom of ammonium appeared in NH$_4$H$_2$PO$_4$ 8/3 me/$\ell$. It suggests that there was the relationship between leaf color and growth condition. It was concluded that NH$_4$H$_2$PO$_4$ 2/3 me/$\ell$ was good before harvest stage and NH$_4$H$_2$PO$_4$ 5/3-6/3 me/$\ell$ at harvest stage.

• Journal of Navigation and Port Research
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• v.37 no.3
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• pp.257-262
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• 2013

A ship operating in rough sea may suffer from an undesirable motion which may severely degrade the performance of equipment onboard and give a person an uncomfortable feeling. Hence, roll stabilization received a considerable attention and various devices including bilge keels, stabilizing fins, gyroscopic, anti-rolling tanks, rudders and flaps have been conceived and utilized for the purpose. The Coanda effect is evident when a jet stream is applied tangential to a curved surface of a hydrofoil since then the jet increases the circulation around the foil and consequently the lift. Model tests and numerical simulation have been conducted to examine the practicality of a fixed type fin stabilizer augmented by the Coanda jet. The results show that the lift coefficient of the modified Coanda fin at the zero angle of attack identically coincides with that of the original fin at ${\alpha}=\26^{\circ}$ when Coanda jet is supplied at the rate of $C_j$ = 0.25. It is also shown that fixed type fin stabilizers for active control of the motions of ships and the other mobile units without rotation can be put to practical use if the Coanda effect is applied.

• Journal of Astronomy and Space Sciences
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• v.20 no.4
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• pp.339-350
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• 2003

Engineering qualification model payload for a communications and broadcasting satellite(CBS) was developed by ETRI from May, 2000 to April, 2003. For. the purpose of functional test and verification of the payload, a real-time hardware-in-the-loop(HITL) CBS simulator(CBSSIM) was also developed. We assumed that the spacecraft platform for the CBSSIM is a geostationary communication satellite using momentum bias three-axis stabilization control technique based on Koreasat. The payload hardware is combined with CBSSIM via Power, Command and Telemetry System(PCTS) of Electrical Ground Support Equipment(EGSE). CBSSIM is connected with PCTS by TCP/IP and the payload is combined with PCTS by MIL-STD-1553B protocol and DC harness. This simulator runs under the PC-based simulation environment with Windows 2000 operating system. The satellite commands from the operators are transferred to the payload or bus subsystem models through the real-time process block in the simulator. Design requirements of the CBSSIM are to operate in real-time and generate telemetry. CBSSIM provides various graphic monitoring interfaces and control functions and supports both pre-launch and after-launch of a communication satellite system. In this paper, the HITL simulator system including CBSSIM, communications payload and PCTS as the medium of interface between CBSSIM and communications payload will be described in aspects of the system architecture, spacecraft models, and simulator operation environment.

• Korean Chemical Engineering Research
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• v.58 no.4
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• pp.565-572
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• 2020

This study developed a software platform using machine learning of artificial intelligence to optimize the distillation column system. The distillation column is representative and core process in the petrochemical industry. Process stabilization is difficult due to various operating conditions and continuous process characteristics, and differences in process efficiency occur depending on operator skill. The process control based on the theoretical simulation was used to overcome this problem, but it has a limitation which it can't apply to complex processes and real-time systems. This study aims to develop an empirical simulation model based on machine learning and to suggest an optimal process operation method. The development of empirical simulations involves collecting big data from the actual process, feature extraction through data mining, and representative algorithm for the chemical process. Finally, the platform for the distillation column was developed with verification through a developed model and field tests. Through the developed platform, it is possible to predict the operating parameters and provided optimal operating conditions to achieve efficient process control. This study is the basic study applying the artificial intelligence machine learning technique for the chemical process. After application on a wide variety of processes and it can be utilized to the cornerstone of the smart factory of the industry 4.0.

• Archives of Craniofacial Surgery
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• v.10 no.1
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• pp.14-18
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• 2009

Purpose: Nasal packing materials are almost inserted at the end stage of closed reduction of nasal bone for postoperative bleeding control and stabilization of nasal bone. Conventionally, vaseline gauze was used for packing of nasal cavity. These days, Surgeons have tried to apply $Merocel^{(R)}$ into the nasal cavity more easily. It is difficult for patients to continue keeping the nasal packs for more than a week due to breathing difficulty. Moreover, nasal packing itself can also cause headache, dry mouth, stuffiness, etc. Methods: We performed a prospective study from March 1, 2008 to July 31, 2008. One hundred patients were divided into "$Merocel^{(R)}$ packing group" and "$Merocel^{(R)}$ and Airway Tube $Merocel^{(R)}$ packing group". Using two kinds of materials to each group after closed reduction, we observed and compared the amount of bleeding between two groups. We recorded patient's uncomfortable symptoms which were divided into four groups each 6, 24, 48 hours after nasal packing. Results: The result of the bleeding amount of Air Tube $Merocel^{(R)}$ group after 6 hours of nasal packing is that 3 people belong to mild group, 38 people moderate group, and 9 people severe group. After 6 hours of nasal packing, 11 patients have no complains. 16 patients were mild, 21 patients were moderate, 2 patients were severe. After 24 hours of nasal packing, no complain(18 patients), mild(24 patients), moderate(6 patients), severe(0 patient). After 48 hours of nasal packing, no complain(25 patients), mild(20 patients), moderate(5 patients), severe(0 patient). Conclusion: Regarding the amount of bleeding, there are no difference between two groups. In case of Air Tube $Merocel^{(R)}$ group, patient's discomfort is gradually improved after 24 hours of nasal packing, After 48 hours of nasal packing, most of the patients do not experience headache, dry mouth, stuffiness, etc. Therefore, Air Tube $Merocel^{(R)}$ can be useful for bleeding control. Moreover, it helps patients to breathe through nose more easily and reduce discomfort.

• Journal of Plant Biology
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• v.35 no.2
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• pp.117-123
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• 1992

The effect of benzyladenine (BA) on lipid peroxidation and compositions of total insoluble proteins and chloroplast thylakoid protein from wheat primary leaves during senescence in the dark was studied. BA ($10^{-5}\;M$) treatment prevented conspicuously the loss of chlorophyll content and soluble and insoluble leaf protein contents in senescing wheat leaf segments during 4-day dark incubation. Under the BA treatment, especially, the level of insoluble protein was highly maintained than that of soluble protein. Also, the increase of malondialdehyde (MDA: the peroxidation product of membrane lipids) content was inhibited in the BA treated leaves. Three major polypeptide bands in quantity corresponding to 57, 26 and 12 KD molecular weight were clearly resolved with other minor bands by SDS-polyacrylamide gel electrophoresis (SDS-PAGE) in the insoluble protein fraction. The insoluble protein profiles of the control leaves showed a remarkable decrease in the intensity of the 57 and 12 KD band except for 26 KD band in the 72 h dark incubation. This loss during dark incubation was reduced by BA treatment. More than 20 polypeptides were resolved in the chloroplast thylakoid membrane fraction with the most prominent bands which are 59 and 57 KD ($\alpha\;and\;\beta$ subunit of coupling factor: CF) and 26 KD (apoprotein of LHCP). The changes in thylakoid protein profile during 72 h dark incubation showed the rapid degradation in control, but this degradation was prevented in quantity by BA treatment. The above results suggested that BA would inhibit the peroxidation of membrane lipids, thereby preventing the loss of membrane proteins which led to the maintenance of the membrane integrity including chloroplast thylakoid.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.643-651
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• 2020

A capsule train runs inside a sub-vacuum tube and can reach very high speed due to the low air resistance. A capsule train uses a superconducting electrodynamic suspension (SC-EDS) method for levitation, which allows for a large levitation gap and does not require gap control. However, SC-EDS has inherent characteristics such as the large gap variation and a small damping effect in the levitation force, which can degrade the running stability and ride comfort. To overcome this, a stability improvement device should be designed and applied based on dynamic analysis. In this study, a 1/10 small-scale testbed was developed to replicate the dynamic characteristics of a capsule train and investigate the performance of stability improvement devices. The testbed is composed of a 6-degree-of-freedom Stewart platform for the realization of bogie motion, a secondary suspension with a running stabilization device, and a carbody. Based on the dynamic similarity law proposed by Jaschinski, the small-scale testbed was manufactured, and a bogie motion algorithm was applied with the consideration of guideway irregularity and levitation stiffness. The experimental results from the testbed were compared with simulation results to investigate the performance of the testbed.