• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.31 no.8
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• pp.19-26
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• 2003

A steady prediction method of dynamic stability derivatives is presented in the unified framework of the unsteady Euler equations. New approach does not require any modification of the governing equations except addition of non-inertial force terms. The present methods are applied to compute the pitch-damping coefficients using the lunar coning and the lunar helical motions in the Cartesian coordinate frame. The results for the ANSR and the Basic Finner are in good agreement with the PNS data, range data, and the results using the unsteady prediction method. The results show that the steady approach using the unified governing equations in the Cartesian coordinate frame can be successfully applied to predict the pitch-damping coefficients.

• Microbiology and Biotechnology Letters
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• v.23 no.2
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• pp.164-169
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• 1995

An endogenous cryptic plasmid, pBL1, which has been used to construct plasmid vectors for coryneform bacteria producing amino acids, was eliminated from Brevibacterium lactofermentum. The pBL1 was partially digested with Sau3AI and the resulting DNA fragments were subcloned into a suicide vector pEM1 which contains a kanamycin-resistant (km$^{r}$) gene. KM$^{r}$ B. lactofermentum transconjugants were obtained by conjugal transfer of the pEM1 derivatives containing pBL1 DNA fragments from Escherichia coli into B. lactofermentum. A km$^{r}$ transconjugant was analyzed to contain a plasmid pEB14, which occurred in vivo by homologous recombination between pBL1 and the conjugal-transferred plasmid. The pEB14 including the pEM1-derived km$^{r}$ gene was found to be lost concomitantly with km$^{r}$ phenotype, resulting in the construction of a pBL1-free strain of B lactofermentum. Based on transformation efficiencies and plasmid stability, the resultant pBL1- free strain is more useful than wild strain as a host cell for genetic manipulation. It could be concluded that foreign plasmid DNAs are efficiently isolated and analyzed from the pBL1-free strain because of the absence of endogenous pBL1 plasmid.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.4 no.1
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• pp.3-10
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• 2018

The folate receptor (FR) is a promising cell membrane-associated target for nuclear imaging of various cancers (via imaging $FR-{\alpha}$) and potentially also inflammatory diseases (via imaging $FR-{\beta}$), through the use of folic acid-based radioconjugates. However, there have been several drawbacks of previously reported radioconjugates, such as a short half-life of the radiolabel ($^{68}Ga\;t_{1/2}$ 68 min), a complex and time-consuming multistep radiosynthesis, and a high renal uptake of radiolabeled folate derivatives. The goal of this study was to develop an imaging probe by directly labeling folate with radioactive iodine without using an extra prosthetic group. The radiolabeling of folate was optimized using various labeling conditions and the labeled tracers were isolated by high-performance liquid chromatography. The in vitro stability of labeled folate was checked in phosphate-buffered saline and serum. The tumor-targeting efficacy of the probe was also evaluated by biodistribution studies using a murine 4T1 tumor model.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.04b
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• pp.124-127
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• 2002

In this study, The cathode interface layer (CIL) was investigated using aromatic diamine derivatives. Cz-TPD (4,4'-biscarbazolyl(9)-biphenyl) used in the cathode interface layers is investigated emition charcaracteristics at the green organic electroluminescent devices. TPD (N,N' -dyphenyl -N -N'-bis (3-methy phenyl)-1,1' -biphenyl-4,4' -diamine) as the hole transformer layer and $Alq_{3}:tris$ (8-hyd-roxyquinoline) aluminium) as the electron transport layer and emiting layer maded use of the organic electroluminescent device. The Organic Electroluminescent Device with Ag cathode and CIL of Cz-TPD(4,4'-biscarbazolyl(9)-biphenyl) showed good EL characteristics compare to a conventional Mg:Ag device and also an improved storage stability. [1] As the change in MgAg, Cz-TPD/Ag, Ag at the chthode, the electrical and optical charcaracteriseics were investigated.

• 한국전산유체공학회:학술대회논문집
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• 1995.10a
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• pp.55-63
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• 1995

The flow field around a high-speed train including cross-wind effects has been simulated. This study solves 3-D unsteady incompressible Navier-Stokes equations in the inertial frame using the iterative time marching scheme. The governing equations are differenced with 1st-order accurate backward difference scheme for the time derivatives, 3th-order accurate QUICK scheme for the convective terms and 2nd-order accurate central difference scheme for the viscous terms. The Marker-and-Cell concept was applied to efficiently solve continuity equation, which is differenced with 2nd-order accurate central difference scheme. The 4th-order artificial damping is added to the continuity equation for numerical stability. A C-H type of elliptic grid system is generated around a high-speed train including ground. The Baldwin-Lomax turbulent model was implemented to simulate the turbulent flows. To validate the present procedure, the flow around a high speed train at constant yaw angle of $45^{\circ}\;and\;90^{\circ}$ has been simulated. The simulation shows 3-D vortex generation in the lee corner. The flow separation is also observed around the rear of the train. It has concluded that the results of present study properly agree with physical flow phenomena.

• Wind and Structures
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• v.25 no.4
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• pp.397-413
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• 2017

When bridges are constructed with lower heights from the ground, the formed channel between the deck and the ground will inevitably hinder or accelerate the air flow. This in turn will have an impact on the aerodynamic forces on the deck, which may result in unexpected wind-induced responses of bridges. This phenomenon can be referred to "ground effects." So far, no systematic studies into ground effects on the wind-induced responses of closed box girders have been performed. In this paper, wind tunnel tests have been adopted to study the ground effects on the aerodynamic force coefficients and the wind-induced responses of a closed box girder. In correlation with the heights from the ground in two ground roughness, the aerodynamic force coefficients, the Strouhal number ($S_t$), the vortex-induced vibration (VIV) lock-in phenomena over a range of wind velocities, the VIV maximum amplitudes, the system torsional damping ratio, the flutter derivatives, the critical flutter wind speeds and their variation laws correlated with the heights from the ground of a closed box girder have been presented through wind tunnel tests. The outcomes show that the ground effects make the vortex-induced phenomena occur in advance and adversely affect the flutter stability.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.10
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• pp.178-184
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• 2007

A new adaptive alternating-direction-implicit finite-difference time-domain (ADI-FDTD) method is proposed to obtain isotropic wave propagation for all directional angles. We add the square terms of time-step multiplied by the spatial derivatives of x and y as a perturbed term to the conventional ADI-FDTD and can find the optimization coefficient of square terms of time-step to generate the minimum anisotropy. The new ADI-FDTD is also stable, even when its time-step is greater than the Courant-Friedrich-Levy (CFL) limit. The characteristic equation of the dispersion relation governing the new method is derived and compared with the theoretical and numerical results for the conventional ADI-FDTD and perturbed ADI-FDTD methods.

• 한국전산유체공학회:학술대회논문집
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• 1996.05a
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• pp.99-104
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• 1996

The jet pump is being used in many fields for several purposes because of its simple construction and easy operation. The characteristics of the geometrical variables, pressure gradient and velocity distribution of the jet pump are studied using the CFD technique. The flow calculations through a bended nozzle. a mixing chamber and a venturi are presented and phenomenological aspects are discussed. This study solve 3-D steady incompressible Navier-Stokes equations using the Iterative time marching scheme. The governing equations are differenced with 1st-order accurate backward difference scheme for the time derivatives and 3rd-order accurate QUICK scheme for the convective terms. The Mark-and-cell concept was applied efficiently to solve continuity equation, which is differenced 2nd-order accurate central differenced scheme. The 4th-order artificial damping is added to the continuity equation for numerical stability. A O-type of grid system is generated inside a nozzle and venturi of the jet pump. It has concluded that the results of present study properly agree with physical flow phenomena.

• Journal of the Korean Applied Science and Technology
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• v.11 no.2
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• pp.121-127
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• 1994

1-(2-hydroxyethyl)-2-undecyl-2-imidazoline[I] was converted into various types of sulfonated or sulfated amphoteric surfactants as following. 1-(2-hydroxyethyl)-1-(3-sulfonatedpropyl)-2-undecyl-2-imidazolium[III] 1-(2-sulfatedethyl)-1-methyl-2-undecyl-2-imidazolium[IV] 1-dioxylethylene methyl sulfonated-1-methyl-2-undecyl-2-imidazoliun[V] N-[N'-(2-hydroxyethyl)-N-(3-sulfonatedpropylammonio]ethyl dodecanoyl amide[VI] Mono sodium N-[N'-(2-hydroxyethyl)-N'-disulfonatedpropylammonio]ethyl dodecanoyl amide[VII] N-[N'-(2-hydroxyethyl-N'-(2-hydroxypropl-N'(3-sulfonatedpropyl)ammonio] ethyl dodecanoyl amide[VIII] The alkylimidazolines could be readily hydrolyzed to give amidoamines, but by quaternerization, hydrolysis stability of imidazoline and amide type amphoteric surfactantes were increased in the alkali and acid conditions. Also, at least three carbon chains introduce to the main group, water solubility was sparingly increased.

• Journal of the Korean Applied Science and Technology
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• v.3 no.1
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• pp.65-71
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• 1986

Four amphoteric surfactants, 1-(N-alkyl-N,N-dimethyl ammonio)-4-naphthalene sulfonates, were prepared by the alkylation of 1-(N,N-dimethylamino)-4,naphthalene sulfonic acid with chloroalkanes such as 1-decylchloride, 1-tetradecyl chloride and 1-hexadecyl chloride. These quaternary ammonium compounds such as 1-(N-decyl-N, N-dimethylammonio)-4-naphthalene sulfonate, 1-(N-dodecyl-N,N-dimethylammonio)-4-naphthalene sulfonate, 1-(N-tetradecyl-N,N-dimethylammonio)-4-naphthalene sulfonate and 1-(N-hexadecyl-N,N-dimethylammonio)-4-naphthalene sulfonate could be separated by means of thin layes chromatography and column chromatography. The surface chemical properties such as surface tension, foaming power, foam stability, wetting efficiency and solubilizing effect for these four compounds were measured. Also critical micelle concentration and hydrophilic-lipophilic balance(HLB) were evaluated. These compounds showed good surface as O/W type emulsifying agent and detergent.