• Clinical and Experimental Reproductive Medicine
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• v.26 no.3
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• pp.441-445
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• 1999

Objective: To analyze the methylenetetrahydrofolate reductase (MTHFR) mutation in recurrent spontaneous abortion associated with hyperhomocysteinemia. Material and Method: The blood sample of habitual aborter with high fasting homocysteine level was tested by PCR - RFLP method. Results: The patient was found to be a homozygosity for MTHFR gene mutation that was confirmed by the finding which is consistent with the mutation at the nucleotide 677 C to T, corresponding to Ala to Val. Conclusions: Hyperhomocysteinemia due to MTHFR mutation is a cause of recurrent spontaneous abortion. Therefore, the MTHFR mutation should be examined in the workup of recurrent spontaneous abortion showing hyperhomocysteinemia.

• Phonetics and Speech Sciences
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• v.10 no.4
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• pp.19-29
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• 2018

The present study investigated whether there are differences in articulation rate by gender, age, and individual speakers in a spontaneous speech corpus produced by 40 Seoul Korean speakers. This study measured their articulation rates using a second-per-syllable metric and a syllable-per-second metric. The findings are as follows. First, in spontaneous Seoul Korean speech, there was a gender difference in articulation rates only in age group 10-19, among whom men tended to speak faster than women. Second, individual speakers showed variability in their rates of articulation. The tendency for some speakers to speak faster than others was variable. Finally, there were metric differences in articulation rate. That is, regarding the coefficients of variation, the values of the second-per-syllable metric were much higher than those for the syllable-per-second metric. The articulation rate for the syllable-per-second metric tended to be more distinct among individual speakers. The present results imply that data gathered in a corpus of Seoul Korean spontaneous speech may reflect speaker-specific differences in articulatory movements.

• Korean Journal of Head & Neck Oncology
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• v.37 no.2
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• pp.101-104
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• 2021

Spontaneous cervical hematomas could lead to life-threatening complications, and aneurysms, retopharyngeal abscesses, parathyroid adenomas, laryngeal cysts, and neurogenic tumors should be distinguished as possible underlying causes. Symptoms accompanying spontaneous cervical hematoma include cervical swelling, ecchymosis, dysphagia, dyspnea and hoarseness. We recently experienced a case of spontaneous cervical hematoma in a 52-year-old woman, who initially presented with cervical swelling after severe coughing two days ago. Resultingly parathyroid adenoma was finally confirmed after mass excision. Therefore, we present this unique case with a review of the literature.

• Clinical and Experimental Reproductive Medicine
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• v.28 no.3
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• pp.209-213
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• 2001

Objective : To evaluate factor XII deficiency in patients with recurrent spontaneous abortion and its relation to aPTT. Material and Method: Factor XII was analyzed by clotting method. Results: Of 70 patients with recurrent spontaneous abortion, there were 35 cases of factor XII deficiency. Among them, there were only 3 cases of prolonged aPTT. Conclusions: It is still unclear whether factor XII deficiency is related to recurrent spontaneous abortion. Molecular approaches should be used to understand further the causal relationship. But based on this result, in the workup of patients with recurrent spontaneous abortion, factor XII should be included. aPTT is not likely to represent the abnormality of factor XII.

• Phonetics and Speech Sciences
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• v.1 no.4
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• pp.85-94
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• 2009

This paper investigates the intonation patterns of Korean spontaneous speech through an analysis of four dialogues in the domain of travel planning. The speech corpus, which is a subset of spontaneous speech database recorded and distributed by ETRI, is labeled in APs and IPs based on K-ToBI system using Momel, an intonation stylization algorithm. It was found that unlike in English, a significant number of APs and IPs include hesitation lengthening, which is known to be a disfluency phenomenon due to speech planning. This paper also claims that the hesitation lengthening is different from the IP-final lengthening and that it should be categorized as a new category, as it greatly affects the intonation patterns of the language. Except for the fact that 19.09% of APs show hesitation lengthening, the spontaneous speech shows the same AP patterns as in read speech with higher frequency of falling patterns such as LHL in comparison with read speech which show more LH and LHLH patterns. The IP boundary tones of spontaneous speech, showing the same five patterns such as L%, HL%, LHL%, H%, LH% as in read speech, show higher frequency of rising patterns (H% and LH%) and contour tones (HL%, LH%, LHL%) while read speech on the contrary shows higher frequency of falling patterns and simple tones at the end of IPs.

• The Korean Journal of Pain
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• v.13 no.1
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• pp.79-83
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• 2000

Background: Spontaneous intracranial hypotension is a syndrome characterized by postural headache without trauma, spinal anesthesia or other medical history. The purpose of this study is to analyze the effect of epidural blood patch in spontaneous intracranial hypotension. Methods: The spontaneous intracranial hypotension patients treated with epidural blood patch were analyzed on the symptoms, radiologic images and methods of epidural blood patch retrospectively by the medical records. Results: Patients had postural headache (15 patients) including nausea/vomiting (10 patients), tinnitus (2 patients), neck stiffness (13 patients), vertigo (3 patients) and occular pain (1 patient). Brain CT and MRI showed diffuse enhancement of the pachymeninges (9 patients) and radionuclide cisternography demonstrated direct evidence of leakage (11 patients). With epidural blood patch, the symptoms were promptly relieved in 11 patients. Conclusions: We concluded that epidural blood patch is a good treatment of method in spontaneous intracranial hypotension patients.

• Clinical and Experimental Reproductive Medicine
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• v.41 no.3
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• pp.140-145
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• 2014

This article reports a case of spontaneous ovarian hyperstimulation syndrome (OHSS) following a thawed embryo transfer cycle. OHSS, a potentially life-threatening condition, is an iatrogenic complication of controlled ovarian stimulation; therefore, it is very important to prevent and treat OHSS during treatment with ovulation-inducing agents. Despite our efforts to prevent OHSS, in this case, severe spontaneous OHSS occurred, which resulted in uncontrolled preterm labor and a preterm delivery and also persisted for 6 weeks after delivery. Freezing all embryos cannot entirely prevent the development of OHSS because OHSS can occur spontaneously. Although spontaneous OHSS remains a rare event, females with a history of OHSS may have an elevated risk for spontaneous OHSS. We suggest closely monitoring cases of pregnancy following thawed embryo transfer for early diagnosis of spontaneous OHSS and the use of conservative management.

• Korean Journal of Biological Psychiatry
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• v.19 no.1
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• pp.17-28
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• 2012

The primary purpose of this review is to present an overview of relationship between human spontaneous eyeblinking and internal cognitive processes. The second purpose is to address the neural substrates of human eyeblinking based on recent studies focusing on the central dopaminergic system and to explore the significance of spontaneous eyeblinks in neuropsychiatric disorders. We reviewed recent and previous studies on eyeblink patterns under various cognitive tasks. We also reviewed neural substrates of eyeblinking, particularly based on the central dopaminergic system. This paper suggests that spontaneous eyeblinks are highly correlated with various cognitive processes and the activity of central dopaminergic system. Various neuropsychiatric disorders are related to the alteration of the occurrence of eyeblinking. Spontaneous eyeblinking is the unique human behavior that occurs regularly without conscious effort. It is known that the rate of eyeblinking is modulated by internal cognitive processes and dopamine-related neuropsychiatric disorders. Further research is required to how the temporal dynamics of spontaneous eyeblinking is correlated with the disease activity and progression.

• Journal of Chest Surgery
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• v.27 no.4
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• pp.292-296
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• 1994

From March, 1985, to June, 1993, 244 patients with 345 episodes of spontaneous pneumothorax treated at Koryo General Hospital were reviewed. Most of the patients were male, and the ratio of male to female was 8:1. The average age of the patients with spontaneous pneumothorax was 32.8 years old. The site of pneumothorax was revealed left side in 53.3%, right side in 42.6%, and bilateral in 4.1%. The cause of pneumothorax were shown primary spontaneous pneumothorax in 73.4%, and secondary spontaneous pneumothorax in 26.6%. The underlying pathologic lesion in secondary spontaneous pneumothorax showed pulmonary tuberculosis in 56patients[86.1%], COPD in 4patients[6.2%], bronchial asthma in 2patients[3.1%], lung cancer in 2patients[3.1%], and pneumoconiosis in a patient[1.5%]. The usual clinical symptomes were dyspnea, chest pain and chest discomfort. Recurrence rate was as follow; 2nd episode 33.6%, 3rd episode in 26.8%, and above in 4th episode in 18.2%. All the patient of pneumothorax was treated as following; Closed thoracostomy tube drainage in 127patients, bullectomy in 88patients, lobectomy in 5patients, wedge resection in 2patients, conservative treatment with oxygen therapy in 21patients, and video assisted thoracoscopic bullectomy in a patient. The course of treatment of all of the patients were smooth and uneventful.

• Journal of the Korean Society of Safety
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• v.31 no.1
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• pp.61-65
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• 2016

In this study, we considered the ignition possibility for the shredded thermoplastic elastomer at the fire ground loaded the waste TPE. The average moisture content of the TPE sample was almost 0.33 wt.% at $110^{\circ}C$ and the range of ignition point was $461.9{\sim}491.9^{\circ}C$ approximately. In addition, we analyzed the change of weight and calorie the TPE sample according to temperature variations using the TG-DTA analyzer. As a result, the weight loss occurred twice in $250{\sim}420^{\circ}C$ and $420{\sim}473^{\circ}C$, and we found the second weight loss temperature range was the ignition point of TPE. Also, we conducted the spontaneous ignition tests of TPE for the wet and dry samples and we confirmed that the possibility of spontaneous ignition of TPE was very low. The elapsed time and humidity had little influence on the spontaneous ignition of TPE in this experimental conditions. In conclusion, the spontaneous of the shredded waste TPE in this study.