• Korean Journal of Ophthalmology
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• 제32권6호
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• pp.506-516
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• 2018

Purpose: We measured the thicknesses of the ganglion cell and inner plexiform layer (GCIPL), the macula, and the retinal nerve fiber layer (RNFL) using spectral-domain optical coherence tomography in patients with idiopathic macula holes to analyze the repeatability of these measurements and compare them with those of the fellow eye. Methods: We evaluated 85 patients who visited our retinal clinic. The patients were divided into two groups according to their macular hole size: group A had a size of $<400{\mu}m$, while group B had a size of ${\geq}400{\mu}m$. Repeatability was determined by comparing the thicknesses of the GCIPL, macula, and RNFL with those of the normal fellow eye. Results: The average central macular thickness in patients with macular holes was significantly thicker than that in the normal fellow eye ($343.8{\pm}78.6$ vs. $252.6{\pm}62.3{\mu}m$, p < 0.001). The average thickness of the GCIPL in patients with macular holes was significantly thinner than that in the normal fellow eye ($56.1{\pm}23.4$ vs. $77.1{\pm}12.8{\mu}m$, p < 0.001). There was no significant difference in the average RNFL thickness between eyes with macular holes and fellow eyes ($92.4{\pm}10.0$ vs. $95.5{\pm}10.7{\mu}m$, p = 0.070). There were also no significant differences in the thicknesses of the GCIPL and RNFL among the two groups (p = 0.786 and p = 0.516). The intraclass correlation coefficients for the macula and RNFL were 0.994 and 0.974, respectively, in patients with macular holes, while that for the GCIPL was 0.700. Conclusions: Macular contour change with macular hole results in low repeatability and a tendency of thinner measurement regarding GCIPL thickness determined via spectral-domain optical coherence tomography. The impact of changes in the macular shape caused by macular holes should be taken into consideration when measuring the GCIPL thickness in patients with various eye diseases such as glaucoma and in those with neuro-ophthalmic disorders.

• 한국광학회:학술대회논문집
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• 한국광학회 2003년도 하계학술발표회
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• pp.254-255
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• 2003

OCT (Optical Coherence Tomography)는 여러 단층영상 촬영기법의 하나로써 절개 없이도 생체의 복잡한 내부구조를 고분해능으로 이미징할 수 있는 장점을 갖고 있다. 고분해능 OCT 이미지는 사용되는 광원에 의해서 결정되는데 가우시안 형태를 갖는 넓은 파장대역의 광원일수록 높은 분해능이 가능하게 된다. OCT에서 사용되는 광원의 종류는 SLD, EELED, ASE등이 사용되고 있다. 그 중에서 ASE광원은 높은 출력 파워를 갖고 넓은 파장대역을 포함하지만 스펙트럼의 형태가 가우시안이 아닌 단점을 가지고 있다. (중략)

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2521-2526
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• 2015

Objective: The purpose of this study was to evaluate computed tomography (CT) virtual non-contrast (VNC) spectral imaging for gastric carcinoma. Materials and Methods: Fifty-two patients with histologically proven gastric carcinomas underwent gemstone spectral imaging (GSI) including non-contrast and contrast-enhanced hepatic arterial, portal venous, and equilibrium phase acquisitions prior to surgery. VNC arterial phase (VNCa), VNC venous phase (VNCv), and VNC equilibrium phase (VNCe) images were obtained by subtracting iodine from iodine/water images. Images were analyzed with respect to image quality, gastric carcinoma-intragastric water contrast-to-noise ratio (CNR), gastric carcinoma-perigastric fat CNR, serosal invasion, and enlarged lymph nodes around the lesions. Results: Carcinoma-water CNR values were significantly higher in VNCa, VNCv, and VNCe images than in normal CT images (2.72, 2.60, 2.61, respectively, vs 2.35, $p{\leq}0.008$). Carcinoma-perigastric fat CNR values were significantly lower in VNCa, VNCv, and VNCe images than in normal CT images (7.63, 7.49, 7.32, respectively, vs 8.48, p< 0.001). There were no significant differences of carcinoma-water CNR and carcinoma-perigastric fat CNR among VNCa, VNCv, and VNCe images. There was no difference in the determination of invasion or enlarged lymph nodes between normal CT and VNCa images. Conclusions: VNC arterial phase images may be a surrogate for conventional non-contrast CT images in gastric carcinoma evaluation.

• 한국광학회:학술대회논문집
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• 한국광학회 2009년도 동계학술발표회 논문집
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• pp.171-172
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• 2009

• 한국광학회:학술대회논문집
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• 한국광학회 2009년도 창립 20주년기념 특별학술발표회
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• pp.117-118
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• 2009

• 한국광학회:학술대회논문집
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• 한국광학회 2007년도 동계학술발표회 논문집
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• pp.44-45
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• 2007

• 한국광학회:학술대회논문집
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• 한국광학회 2006년도 동계학술발표회 논문집
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• pp.187-188
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• 2006

• 한국광학회:학술대회논문집
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• 한국광학회 2008년도 하계학술발표회 논문집
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• pp.279-280
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• 2008

• 한국광학회:학술대회논문집
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• 한국광학회 2008년도 하계학술발표회 논문집
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• pp.281-282
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• 2008

• 한국광학회:학술대회논문집
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• 한국광학회 2008년도 하계학술발표회 논문집
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• pp.163-164
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• 2008