• The Journal of Internal Korean Medicine
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• v.40 no.3
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• pp.557-565
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• 2019

Objectives: This study investigated the effect of local acupuncture point stimulation and the application of a topical herbal mixed heating cream in a chronic cough patient who had not responded to various medications for more than a few months. Methods: An 81 year-old female patient who was suspected to be suffered from Upper Airway Cough Syndrome (UACS) was examined. The patient was treated with local acupuncture point stimulation and the application of a topical herbal mixed heating cream. We used the Leicester Cough Questionnaire, Cough-Specific Quality-of-Life Questionnaire, and Verbal Numerical Rating Scale to assess the patient's respiratory symptoms. Results: Local acupuncture point stimulation and the application of a topical herbal mixed heating cream resulted in the improvement of cough symptoms. The quality of life due to the alleviation of symptoms also significantly improved. Adverse effects were not observed. Conclusions: This study suggests that local acupuncture point stimulation and the application of a topical herbal mixed heating cream may be an effective therapy for the treatment of chronic cough in patients with UACS.

• Journal of Astronomy and Space Sciences
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• v.38 no.2
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• pp.145-155
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• 2021

In this work, preliminary launch opportunities from NARO Space Center to the Sun-Earth Lagrange point are analyzed. Among five different Sun-Earth Lagrange points, L1 and L2 points are selected as suitable candidates for, respectively, solar and astrophysics missions. With high fidelity dynamics models, the L1 and L2 point targeting problem is formulated regarding the location of NARO Space Center and relevant Target Interface Point (TIP) for each different launch date is derived including launch injection energy per unit mass (C3), Right ascension of the injection orbit Apoapsis Vector (RAV) and Declination of the injection orbit Apoapsis Vector (DAV). Potential launch periods to achieve L1 and L2 transfer trajectory are also investigated regarding coasting characteristics from NARO Space Center. The magnitude of the Lagrange Orbit Insertion (LOI) burn, as well as the Orbit Maintenance (OM) maneuver to maintain more than one year of mission orbit around the Lagrange points, is also derived as an example. Even the current work has been made under many assumptions as there are no specific mission goals currently defined yet, so results from the current work could be a good starting point to extend diversities of future Korean deep-space missions.

• Communications for Statistical Applications and Methods
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• v.30 no.4
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• pp.369-388
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• 2023

In this paper, we develop the two-step procedure that detects and estimates the position of structural changes for multivariate nonstationary time series, either on mean parameters or second-order structures. We first investigate the presence of mean structural change by monitoring data through the aggregated cumulative sum (CUSUM) type statistic, a sequential procedure identifying the likely position of the change point on its trend. If no mean change point is detected, the proposed method proceeds to scan the second-order structural change by modeling the multivariate nonstationary time series with a multivariate locally stationary Wavelet process, allowing the time-localized auto-correlation and cross-dependence. Under this framework, the estimated dynamic spectral matrices derived from the local wavelet periodogram capture the time-evolving scale-specific auto- and cross-dependence features of data. We then monitor the change point from the lower-dimensional approximated space of the spectral matrices over time by applying the dynamic principal component analysis. Different from existing methods requiring prior information on the type of changes between mean and covariance structures as an input for the implementation, the proposed algorithm provides the output indicating the type of change and the estimated location of its occurrence. The performance of the proposed method is demonstrated in simulations and the analysis of two real finance datasets.

• International Journal of Korean Welding Society
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• v.2 no.2
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• pp.14-18
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• 2002

Titanium and titanium alloy are excellent in corrosion resistance and specific intensity, and also in the biocompatibility. On the other hand, the brazing is bonding method of which productivity and reliability are high, when the complicated and precise structure of the thin plate is constructed. However, though conventional titanium-based brazing filler metal was excellent in bond strength and corrosion resistance, it was disadvantageous that metal structure and mechanical property of the base metal deteriorated, since the brazing temperature ( about $1000^{\circ}C$ ) is considerably high. Authors developed new brazing filler metal which added Zr to Ti-Cu (-Ni) alloy which can be brazed at $900^{\circ}C$ or less about 15 years ago. In this paper, the development of more low-melting-point brazing filler metal was tried by the addition of the fourth elements such as Ni, Co, Cr for the Ti-Zr-Cu alloy. As a method for finding the low-melting-point composition, eutectic composition exploration method was used in order to reduce the experiment point. As the result, several kinds of new brazing filler metal such as 37.5Ti-37.5-Zr-25Cu alloy (melting point: $825^{\circ}C$) and 30Ti-43Zr-25Cu-2Cr alloy (melting point: $825^{\circ}C$) was developed. Then, the brazing joint showed the characteristics which were almost equal to the base metal from the result of obtaining metallic structure and strength of joint of brazing joint. However, the brazing filler metal composition of the melting point of $820^{\circ}C$ or less could not be found. Consequentially, it was clarified that the brazing filler metal developed in this study could be practically sufficiently used from results such as metal structure of brazing joint and tensile test of the joint.

• Journal of Environmental Science International
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• v.24 no.8
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• pp.1045-1053
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• 2015

This study evaluated the effect of water level of water resources on water quality in Ulsan. Two reservoirs, Sayeon Dam and Hoeya Dam, were selected and water quality of chemical oxygen demand (COD), total nitrogen (TN) and total phosphorus (TP) were analyzed from 2012 to 2014. And the characteristics of precipitation were also analyzed for 70 years (1945~2014) because runoff of non-point pollutant was strongly affected by precipitation. As a result, water deterioration of Sayeon Dam and Hoeya Dam were affected in accordance with lowering water level. For example, the concentrations of COD and TN was negatively correlated with the water level when the water level of Sayeon Dam was gradually decreased in 2013. The TN concentration was increased to 1.432 mg/L from 0.875 mg/L while the lowest water level of Sayeon Dam was recorded 45 m in 2014. Additionally the concentration of COD and TN was sensitively increased with 0.213 mg/L/m and 0.058 mg/L/m on account of non-point pollutant runoff. It is indicated that hereafter a control of non-point pollutant runoff is the critical factors to maintain water resources because the contribution of non-point pollutant is expected to increase due to the frequent heavy rain events. Therefore, it is necessary to map out a specific plan for non-point pollutant control based on analyses of runoff characteristics, water pollution sources and reduction plans in water pollutants and to establish a water modelling and database system as a preventive action plan.

• Journal of Korean Society for Atmospheric Environment
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• v.25 no.3
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• pp.219-236
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• 2009

Particle-phase organic tracers (molecular markers) have been shown to be an effective method to assess and quantify the impact of sources of carbonaceous aerosols. These molecular markers have been used in chemical mass balance (CMB) models to apportion primary sources of organic aerosols in regions where the major organic aerosol source categories have been identified. As in the case of all CMB models, all important sources of the tracer compounds must be included in a Molecular Marker CMB (MM-CMB) model or the MMCMB model can be subject to biases. To this end, the application of the MM-CMB models to locations where reasonably accurate emissions inventory of organic aerosols are not available, should be performed with extreme caution. Of great concern is the potential presence of industrial point sources that emit carbonaceous aerosols and have not been well characterized or inventoried. The current study demonstrates that emissions from industrial point sources in the St. Louis, Missouri area can greatly bias molecular marker CMB models if their emissions are not correctly addressed. At a sampling site in the greater St. Louis Area, carbonaceous aerosols from industrial point sources were found to be important source of carbonaceous aerosols during specific time periods in addition to common urban sources (i.e. mobile sources, wood burning, and road dust). Since source profiles for these industrial sources have not been properly characterized, method to identify time periods when point sources are impacting a sampling site, needs to avoid obtaining biases source apportionment results. The use of real time air pollution measurements, along with molecular marker measurements, as a screening tool to identify when point sources are impacting a receptor site is presented.

• Proceedings of the KWS Conference
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• 2002.10a
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• pp.539-544
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• 2002

Titanium and titanium alloy are excellent in corrosion resistance and specific intensity, and also in the biocompatibility. On the other hand, the brazing is bonding method of which productivity and reliability are high, when the complicated and precise structure of the thin plate is constructed. However, though conventional titanium-based brazing filler metal was excellent in bond strength and corrosion resistance, it was disadvantageous that metal structure and mechanical property of the base metal deteriorated, since the brazing temperature (about 1000 C) is considerably high. Authors developed new brazing filler metal which added Zr to Ti-Cu (-Ni) alloy which can be brazed at 900 C or less about 15 years ago. In this paper, the development of more low-melting-point brazing filler metal was tried by the addition of the fourth elements such as Ni, Co, Cr for the Ti-Zr-Cu alloy. As a method for finding the low-melting-point composition, eutectic composition exploration method was used in order to reduce the experiment point. As the result, several kinds of new brazing filler metal such as 37.5Ti-37.5-Zr-25Cu alloy (melting point 825 C) and 30Ti-43Zr-25Cu-2Cr alloy (melting point: 825 C) was developed. Then, the brazing joint showed the characteristics which were almost equal to the base metal from the result of obtaining metallic structure and strength of joint of brazing joint. However, the brazing filler metal composition of the melting point of 820 C or less could not be found. Consequentially, it was clarified that the brazing filler metal developed in this study could be practically sufficiently used from results such as metal structure of brazing joint and tensile test of the joint.

• Journal of Acupuncture Research
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• v.20 no.2
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• pp.195-203
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• 2003

Objective : In this thesis we researched ${\ll}$Huangdimingtangjing(黃帝明堂經)${\gg}$ Methods : We refered to ${\ll}$Mingtangkongxuezhenjiuzhiyao(明堂孔穴鍼灸治要)${\gg}$ in ${\ll}$Huangdijiayijing(黃帝甲乙經)${\gg}$ and ${\ll}$Huangdineijingmingtang(黃帝內徑明堂)${\gg}$ Results and Conclusions : ${\ll}$Huangdimingtangjing(黃帝明堂經)${\gg}$ was written between West-Han(西漢) dynasty and East-Han(東漢) dynasty which was a summarized book about acupuncture point before Han(漢) dynasty. 1. "MIngtang(明堂)" means originally the hall where the emperor carried out politics but became a pronoun of acupuncture point in the field of Oriental medicine. 2. ${\ll}$Huangdimingtangjing(黃帝明堂經)${\gg}$ contains Five-elements theory which is specific property of Han(漢) dynasty. A many same named acupuncture point gathered not until Wu(武) emperor. The acupuncture point named "Jimen(期門)" which is the name of a military officer in Wu(武) emperor and cannot be found in ${\ll}$Huangdineijing(黃帝內徑)${\gg}$, I contains "long(隆)" which is the name of Shang(傷) emperor. As such it was written between West Han(漢) dynasty and Esst Han(漢) dynasty. 3. ${\ll}$Huangdimingtangjing(黃帝明堂經)${\gg}$ can be assumed the original edition by ${\ll}$Migtangkongxuezhenjiuzhiyao(明堂孔穴鍼灸治要)${\gg}$ in ${\ll}$Huangdijiayijing(黃帝甲乙經)${\gg}$ and ${\ll}$Huangdineijingmingtang(黃帝內徑明堂)${\gg}$ 4. The scholarship value of ${\ll}$Huangdimingtangjing(黃帝明堂經)${\gg}$ is rich in acupuncture point which described in detail futher more made possible of wide treatment. And also it referred a subordination of five shu(兪) acupuncture point ${\ll}$Huangdineijing(黃帝內徑)${\gg}$.

• Korean Journal of Acupuncture
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• v.22 no.1
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• pp.7-21
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• 2005

Objectives : In the present study, the effect of electroacupuncture (EA) applied to SI6 and won-rak point on the ankle sprain model was examined. A common source of persistent pain in humans is the lateral ankle sprain. Methods : To model this condition, the rat's right ankle was bent repeatedly, overextending lateral ligaments, for 4 min under enflurane anesthesia. The rat subsequently showed swelling of the ankle and a reduced stepping force of the affected limb for the next several days. The reduced stepping force of the limb was presumably due to a painful ankle. EA was applied to the several acupuncture point on the contralateral forelimb for 30 min under gaseous anesthesia. After the termination of EA, behavioral tests measuring stepping force and Paw volume were Periodically conducted during the next 4 h and 18 h respectively. Results : EA applied to $SI_6$ with won-rak point produced more powerful improvement of stepping force of the sprained foot than to $SI_6$ alone lasting for at least 4 h. However, neigher $KI_4$ point nor $BL_{64}$ point produced any significant increase of weight bearing force. The improvement of stepping pressure was interpreted as an analgesic effect. The analgesic effect was specific to the acupuncture point since the analgesic effort on the ankle sprain pain model could not be mimicked by EA applied to $KI_4$ or $BL_{64}$. In addition, EA applied to $SI_6$ with won-rak combination point showed inhibitory effect on the paw edema induced by ankle sprain. Also, COX-2 protein expression increased by ankle sprain were suppressed by the EA stimulation. Conclusion : These data suggest that EA with won-rak combination point produces a more potent analgesic effect on the ankle sprain pain model in the rat and that EA with won-rak combination point induced anti-inflammatory effect through the suppression of COX-2 protein expression.

• Korean Journal of Acupuncture
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• v.21 no.3
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• pp.59-76
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• 2004

Objectives : The usage of acupuncture has gained popularity for certain chronic pain conditions. However, the efficacy of acupuncture in various diseases has not been fully established and the underlying mechanism is not clearly understood. In the present study, the effect of electroacupuncture (EA) applied to yangno$(SI_6)$ on the neuropathic pain was examined. Methods : A common source of persistent pain in human is a neuropathic pain. Neuropathic pain was induced by tight ligation of L5 spinal nerve. When rats developed pain behaviors, EA was applied for 30 min. under enflurane anesthesia with repeated train stimuli at the intensity of 10X of muscle twitch threshold. The foot withdraw latency of the hind limb was measured for an indicator of pain level after each manipulation. Results : EA increased the mechanical threshold of the foot in the rat model of neuropathic pain significantly for the duration of 1 hr. suggesting a partial alleviation of pain. EA applied to SI6 point produced a significant improvement of mechanical sensitivity of the foot lasting for at least 1 h. However, $ST_{36}$ point did not produce any significant increase of mechanical sensitivity. The improvement of mechanical threshold was interpreted as an analgesic effect. The analgesic effort was specific to the acupuncture point since the analgesic effect on the neuropathic pain model could not be mimicked by EA applied to a point, $ST_{36}$. In addition, this analgesic effect of EA is mediated by a adrenergic mechanism of descending control of spinal cord from the brain. Conclusions : The data suggest that EA produces a potent analgesic effect on the neuropathic pain model in the rat; and 2) that EA-induced analgesia is mediated by a adrenergic mechanism of descending control in a point specific manner.