• Title/Summary/Keyword: Spec cPL

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A comparative analysis of canine pancreatic lipase tests for diagnosing pancreatitis in dogs

  • Jin-Kyung Kim;Sun Young Hwang;Se Eun Kim;Gahyun Lee;Soungjin Ji;Jungho Kim;Yongbaek Kim
    • Journal of Veterinary Science
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    • v.25 no.3
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    • pp.48.1-48.12
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    • 2024
  • Importance: Early diagnosis of canine pancreatitis is challenging due to non-specific clinical signs. Currently, abdominal ultrasonography and measurement of canine pancreatic lipase (cPL) have been employed for the diagnosis of pancreatitis. Objective: Many qualitative and quantitative commercial cPL tests have been developed and used in veterinary clinics. This study aimed to compare three different methodologies SNAP cPL, Spec cPL, and Vcheck cPL tests to assess the concordance of these assays. Methods: Fifty serum samples were collected from 36 dogs with or without pancreatitis and subjected to SNAP cPL, Spec cPL, and Vcheck cPL tests. Agreement and correlation coefficients were calculated between the test results, and correlations were determined during the management of the patients. Results: The results of the three cPL assays were strongly correlated in 47/50 serum samples (94%). Cohen's kappa analysis between the Spec cPL and Vcheck cPL showed near perfect agreement (κ = 0.960, p < 0.001), SNAP cPL and Vcheck cPL (κ = 0.920, p < 0.001), and Spec cPL and SNAP cPL (κ = 0.880, p < 0.001). The correlation coefficients (r) between data from Spec cPL and Vcheck cPL tests was calculated by Spearman's correlation test (r = 0.958, p < 0.001). Furthermore, the patterns of change in serum cPL concentrations determined using Spec cPL and Vcheck cPL were significantly consistent during the monitoring period in 11 patients. Conclusions and Relevance: Our data illustrated that Spec cPL and Vcheck cPL tests are compatible for clinical use in the diagnosis and monitoring of canine pancreatitis.

Correlating two-dimensional shear wave elastography of acute pancreatitis with Spec cPL in dogs

  • Cho, Hyun;Yang, Seungwhwa;Suh, Gukhyun;Choi, Jihye
    • Journal of Veterinary Science
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    • v.23 no.5
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    • pp.79.1-79.11
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    • 2022
  • Background: Pancreatitis is a common disease in which 37% of dogs had evidence of acute or chronic pancreatitis at necropsy. Although biopsy is still the gold standard to diagnose acute pancreatitis, clinical data including ultrasonographic findings and measurement of canine serum pancreatic lipase immunoreactivity (cPLI) are used in routine. However, it may be insufficient in the diagnostic approach to acute pancreatitis. Objectives: To evaluate the clinical diagnostic feasibility of two-dimensional shear wave elastography (2D SWE) on canine acute pancreatitis for enhanced diagnostic confidence. Methods: 2D SWE was used to assess pancreatic stiffness and determine the correlation between pancreatic shear wave velocity (SWV) and Spec cPL concentration in 31 dogs with healthy pancreas and 10 dogs with acute pancreatitis. Results: The pancreatic SWV was significantly higher in the acute pancreatitis group (2.67 ± 0.20 m/s) than in the healthy pancreas group (2.30 ± 0.26 m/s; p < 0.05). The moderate positive correlation was found between the pancreatic SWV and Spec cPL concentration (95% confidence interval, 0.214-0.693; r = 0.489; p < 0.05). Conclusions: These results indicated that 2D SWE was feasible for assessing pancreatic stiffness in acute pancreatitis, and that pancreatic SWV using 2D SWE correlated with Spec cPL concentration. SWE could provide a quantitative measure of pancreatic stiffness, which can increase the accuracy of diagnosing acute pancreatitis in dogs. The 2D SWE can be used as a complementary imaging modality for diagnosing acute pancreatitis in dogs.

$CH_4$$N_2$ 가스 혼합비에 따른 a-C:H:N 박막의 물성 연구

  • 유영조;김효근;오재석
    • Proceedings of the Korean Vacuum Society Conference
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    • 1998.02a
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    • pp.94-94
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    • 1998
  • 최근 a-CH:N (hydrogenated amorphous carbon nitride)가 a-CH 보다 팡학적, 기계객성 질이 우수하므로 이에 대한 연구가 활발하게 진행되고 있다. 본 실험에선 원료 가스의 유량 은 5 sccm으로 고정시킨 채 원료가스내의 질소 대 메탄 혼합비 (N2ICHa)훌 O 에서 4 까지 변 화시 키 띤서 DC saddle-field PECVD (plasma enhanced chemical vapour d야Xlsition)훌 이 용하여 a-CH:N 박막융 제작하여, 가스 혼합비가 박막의 미세구조와 광학척 성질에 미치는 영향올 연구하였다. 박막 성장시 진공조 내의 압력온 throttle valve롤 사용하여 90 mTorr로 일정하게 유지하였으며 양극 전압과 기판전업은 각각 500 V, 200 V로 고청하고 상온에서 중 착하였다. a a -step으로 측정 한 a-C:H:N 박막의 두께는 혼합가스내의 질소의 양이 증가할수륙 4800 A에서 2000 A로 두께가 감소하였지만 표면 rot핑비less는 혼합가스내의 질소의 양이 중가할 수록 중가함을 AFM (atomic force mi$\alpha$'0 scopy) 으로 관찰하였다. 박막내의 C와 N의 정량 분석은 RES (Rutherford back scattering s야ctroscopy) 핵공명법을 이용하여 분석하였다. X XPS (X -ray photoelectron spec$\sigma$oscopy) 와 FT-IR (Fo삐er transform-infrared s spectrometry)로 미세구조률 측정한 결과 혼합가스내의 질소의 양이 충가할수록 C-H기는 감 소하였지 만 C르N, N-H기 는 늘어 났다. 또한 PL (photoluminescence) 측정 결과 웬료가스 내 메탄과 질소의 비율이 1:1일 때 최대의 발광올 보였고 UVS (비없 vi이et spec$\sigma$orne$\sigma$y)으 로 측정한 광학쩍 에너지 캡은 혼합비내의 질소의 양이 증가할수록 2.53 eV에서 2.3 eV로 감 소하였다. 이를 결과로부터 원료가스내의 N2ICHa의 중가에 따른 박막의 미세구조 변화와 광학척 생 질의 상관 관계가 고찰될 것이다.

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Performance Analysis of the Multi-User Detector Employing a Hybrid Interference Cancellation Scheme in a WCDMA System (WCDMA 시스템에서 Hybrid Interference Cancellation 기법을 적용한 다중사용자 검파기의 성능분석)

  • 서정욱;오창헌;장은영;조성준
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.6 no.2
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    • pp.221-227
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    • 2002
  • In this paper, in order to know the effect of the interference, we have analyzed the BER (Bit Error Rate) performance of the MUD(Multi-User Detector) employing HIC(Hybrid Interference Cancellation) scheme for the asynchronous WCDMA system based on 3GPP(3rd Generation Partnership Project) Spec. through the In this paper, in order to know the effect of the interference, we have analyzed the BER (Bit Error Rate) performance of the MUD(Multi-User Detector) employing HIC(Hybrid Interference Cancellation) scheme for the asynchronous WCDMA system based on 3GPP(3rd Generation Partnership Project) Spec. through the computer simulation. we have assumed Rayleigh fading channel. And we have compared its BER performance with SIC's(Successive Interference Cancellation) and with PIC's(Parallel Interference Cancellation), which are the representative schemes in the subtractive interference cancellation. From the results, it is shown that PlC or HIC is effective for high data-rate users and SIC of HIC for low data-rate users to eliminate the interference. Regardless of the data rate, it is reasonable to use the HIC structure for WCDMA system to satisfy all of users' services. The reason is that the SIC scheme in front of HIC can guarantee the performance of low power users to cancel the serious interference caused by the high power users, while PIC in the rear of it can guarantee the performance of high power users to cancel the interference caused by the low power users.