• Title/Summary/Keyword: Space Amplification

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Designing a Molecular Diagnostic Laboratory for Testing Highly Pathogenic Viruses (고병원성 바이러스 검사를 위한 분자진단검사실 구축)

  • Jung, Tae Won;Jung, Jaeyoung;Kim, Sunghyun;Kim, Young-Kwon
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.2
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    • pp.143-150
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    • 2021
  • The recent spread of novel and highly variant pathogenic viruses, including the coronavirus (SARS-CoV-2), has increased the demand for diagnostic testing for rapid confirmation. This has resulted in investigating the functional capability of each space, and preparing facility guidelines to secure the safety of medical technologists. During viral evaluations, there is a requirement of negative pressure facilities along with thread separation, during pre-treatment of samples and before nucleic acid amplification. Space composition therefore needs to be planned by considering unidirectional air flow. This classification of safety management facilities is designated as biosafety level 2, and personal protective equipment is placed accordingly. In case of handling dangerous materials, they need to be carried out of the biosafety cabinet, and sterilizers are required for suitable disposal of infectious agents. A common feature of domestic laboratories is maintenance of the sample pre-treatment space at a negative pressure of -2.5 Pa or less, and arranging separate pre-treatment and reagent preparation spaces during the test process. We believe that the data generated in this study is meaningful, and offers an efficient direction and detailed flow for separation of the inspection process and space functions. Moreover, this study introduces construction of the laboratory by applying the safety management standards.

Seismic performance evaluation of middle-slab vibration damping rubber bearings in multi-layer tunnel through full-scale shaking table (실대형 진동대 시험을 통한 복층터널 중간 슬래브 진동 감쇠 고무받침 내진성능 평가)

  • Jang, Dongin;Park, Innjoon
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.22 no.4
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    • pp.337-346
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    • 2020
  • Traffic jam and congestion in urban areas has caused the need to improve the utility of underground space. In response, research on underground structures is increasingly being conducted. Notably, a double-deck tunnel is one of the most widely used of all those underground structures. This double-deck tunnel is separated by the middle slab into the upper and lower roadways. Both vehicle load and earthquake load cause the middle slab to exhibit dynamic behavior. Earthquake-related response characteristics, in particular, are highly complex and difficult to interpret in a theoretical context, and thus experimental research is required. The aim of the present study is to assess the stability of a double-deck tunnel's middle slab of the Collapse Prevention Level and Seismic Category 1 with regard to the presence of vibration-damping Rubber Bearings. In vibration table tests, the ratio of similitude was set to 1/4. Linings and vibrating platforms were fixed during scaled model tests to represent the integrated behavior of the ground and the applied models. In doing so, it was possible to minimize relative behavior. The standard TBM cross-section for the virtual double-deck tunnel was selected as a test subject. The level of ground motion exerted on the bedrock was set to 0.154 g (artificial seismic wave, Collapse Prevention Level and Seismic Category 1). A seismic wave with the maximum acceleration of 0.154 g was applied to the vibration table input (bedrock) to analyze resultant amplification in the models. As a result, the seismic stability of the middle slab was evaluated and analyzed with respect to the presence of vibration-damping rubber bearings. It was confirmed that the presence of vibration-damping rubber bearings improved its earthquake acceleration damping performance by up to 40%.

Neurophysiology of Amplification and Mutation of Poetic Sense: Focusing on Hwang Jin-yi's Sijo "I do not untrustworthy"

  • Park, In-Kwa
    • International Journal of Advanced Culture Technology
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    • v.6 no.2
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    • pp.100-106
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    • 2018
  • Sometimes, literary therapy is to create an abscission layer at the mind and remove the signifier of love, by the abscission layer. The purpose of this study is to reveal the mechanism of literary therapy by mutation in human-created sentences and to activate literary therapy. In Gosijo, the abscission layer of Seo Gyeongdok's mind is present in the layer of the "falling leaf" of the his Sijo's last sentence, and the abscission layer of Hwang Jin-yi's mind exists in the layer of the "falling leaf" of the her Sijo's last sentence. The "falling leaf" created by the abscission layer of Seo Gyeongdok's sentence acts as an action potential to the nervous system of Hwang Jin-yi. In Hwang Jin-yi's Sijo, the abscission layer is also activated, forming a "leaf". Hwang Jin-yi's Sijo constructs a new sensory layer that is extended and mutated more than the meaning of space between lines of Seo Gyeongdok's Sijo. In her Sijo, Hwang Jin-yi twists and twists Seo Gyeongdok's sentences to squeeze the sound. She accepts the Seo Gyeongdok's sentences and twists in the first sentence and twists out of the second sentence once more to produce the mutation in the last sentence. As a result of her sentence twist, Seo Kyung-duk's visual sense of "falling leaf" is mutated into a "falling leaf's sound" of auditory sense. This mutation process works as a healing mechanism in the human body. If this study will continue in the future, it will be possible to activate literary therapy by Sijo.

An Automatic Measuring System of the Electric Fields Produced by Lightning Strokes (뇌방전에 의하여 발생하는 전장의 자동측정시스템)

  • Lee, Bok-Hee;Ahn, Chang-Hwan;Kil, Gyung-Suk
    • Journal of Sensor Science and Technology
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    • v.5 no.2
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    • pp.47-54
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    • 1996
  • This paper deals with the electric field sensor and automatic measuring system of the time-varying space electric field produced by lightning discharges. The theoretical principle and the design rule of the measuring devices are investigated, and the semisphere-type electric field sensor and the signal process system are fabricated. From the calibration experiments, the frequency bandwidth of the measuring system ranges from 200 [Hz] to 1.56 [MHz] and the sensitivity is 0.96 [m V/V/m] as the amplification gain is 10. In addition, the electric field waveforms produced by lightning discharges are observed by the proposed electric field measuring system from June to August in 1995. The data is sampled with the time interval of 200 [ns] and is automatically recorded by transient signal analyzer(Necolet Pro 30), the resolution of which is 12 bit. And it is registered at personal computer. The electric field waveforms produced by intracloud discharge tend to be bipolar, with two or three narrow and fast rising pulses superimposed on the initial half-cycle.

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Simplified Static Analysis of Superstructure on Very Large Floating Structures subjected to Wave Loads (파랑하중을 받는 초대형 부유식 구조물 상부구조체의 실용정적해석법)

  • Song, Hwa-Cheol;Park, Hyo-Seon;Seo, Ji-Hyun
    • Journal of Navigation and Port Research
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    • v.27 no.5
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    • pp.519-526
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    • 2003
  • For preliminary structural analysis of superstructures on very large floating structures(VLFS), superstructures are analyzed considering elastic deformations of barge type lower-structures subjected to wave loads. In this case, to consider the effect of wave loads on the superstructure, initial displacements at the support points of superstructures are evaluated as input data for the analysis. However, the evaluation and application of displacement loads are tedious and very time-consuming processes. Therefore, this paper proposes a simplified static analysis method to analyze the structural behaviors of superstructures on very large floating structures subjected to wave loads. In this study, the member forces due to the variation of beam span and the amplitude and period of wave load are analyzed by using an example 4 span -3 story structure and the amplification factors for beam moments are represented by the specific regression equation.

Outbreak of carprine arthritis-encephalitis in dairy goat flocks (유산양에서 관절염.뇌염 발생)

  • Son So-Yeon;Son Hyeon-Soo;Ryu Dae-Yeol;Kang Sin-Seok;Park Jae-Myoung;Byeon Hyeon-Seop;Choi Hae-Yeon
    • Korean Journal of Veterinary Service
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    • v.29 no.3
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    • pp.309-316
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    • 2006
  • This is a case report on the occurrence of caprine arthritis-encephalitis (CAE) disease among dairy goats in a local farm located in Yeongdong-gun, Chungbuk. Previously, it was reported that the farm experienced intermittent deaths numbering 15 of the 97 goats raised for 5 months. Most of the goats less than 6 months of age were suffering from ataxia and posterior paresis, body tremor and abnormal head posterior. Affected animals frequently had stunted growth and had a rough coat. Goats more than 6 months of age were affected with an insidious, chronic arthritis characterized by articular swelling ('big knee') of the carpal, hock, and stifle joints. Necropsy revealed severely swollen mesenteric lymph nodes, under- flow of 2-3ml synovial fluid in the articular space and fibrous proliferation of synovial membrane. Histopathological examination showed perivascular accumulations of mononuclear inflammatory cells in the white matter of the brain, proliferative synovitis characterized by villous hypertrophy, synovial cell hyperplasia and infiltration by mononuclear inflammatory cells. Pulmonary lesions consists of patchy interstitial pneumonia with hyperplasia of lymphoid tissues and an extensive mononuclear inflammatory cell infiltration into the alveolar septa. Confirmation by nested PCR involves amplification of a 296 bp (lst PCR) and 184 bp (2nd PCR) fragments corresponding to the gag region of the CAE virus. This is the first time CAE has been reported in a local farm in Korea and emphasizes the importances of developing preventive measures against CAE.

Characterization of the Resonant Caustic Perturbation

  • Chung, Sun-Ju
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.1
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    • pp.48.1-48.1
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    • 2010
  • Four of nine exoplanets found by microlensing were detected by the resonant caustic, which represents the merging of the planetary and central caustics at the position when the projected separation of a host star and a bounded planet is s~1. One of the resonant caustic lensing events, OGLE-2005-BLG-169, was a caustic-crossing high-magnification event with A_max ~800 and the source star was much smaller than the caustic, nevertheless the perturbation was not obviously apparent on the light curve of the event. In this paper, we investigate the perturbation pattern of the resonant caustic to understand why the perturbations induced by the caustic do not leave strong traces on the light curves of high-magnification events despite a small source/caustic size ratio. From this study, we find that the regions with small magnification excess around the center of the resonant caustic are rather widely formed, and the event passing the small-excess region produces a high-magnification event with a weak perturbation that is small relative to the amplification caused by the star and thus does not noticeably appear on the light curve of the event. We also find that the positive excess of the inside edge of the resonant caustic and the negative excess inside the caustic become stronger and wider as q increases, and thus the resonant caustic-crossing high-magnification events with the weak perturbation occur in the range of q $\leq$ 10-4. We determine the probability of the occurrence of events with the small excess $|\varepsilon|{\leq}3%$ in high-magnification events induced by a resonant caustic. As a result, we find that for the Earth-mass planets with a separation of ~2.5 AU the resonant caustic high-magnification events with the weak perturbation can occur with a significant frequen.

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Seismic Response Analysis of a Floating Bridge with Discrete Pontoons (이산폰툰형 부유식교량의 지진응답해석)

  • Kwon, Jang-Sup
    • Journal of the Earthquake Engineering Society of Korea
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    • v.9 no.2 s.42
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    • pp.47-58
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    • 2005
  • Dynamic response analysis in time dimain is conducted for floating bridges with discrete pontoons subject to spatial variation of ground motions. The Spatial variation of ground motions is considered with the coherency function model which represents wave passage, incoherence and local site effects. The superstructure of the bridge is represented by space frame and elastic catenary cable elements, the abutment us modelde with the spring element of FHWA guideline for considering soil structure interaction and the concept of retardation function is utilized to consider the frequency dependency of the hydrodynamic coefficients which are obtainde by boundary element method. multiple support excitations considering the spatial variation. The noticeable amplification of the response can be shown when the spatial variation of ground motions is incorporated in the anallysis of floating bridges.

Compressible Simulation of Rotor-Stator Interaction in Pump-Turbines

  • Yan, Jianping;Koutnik, Jiri;Seidel, Ulrich;Hubner, Bjorn
    • International Journal of Fluid Machinery and Systems
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    • v.3 no.4
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    • pp.315-323
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    • 2010
  • This work investigates the influence of water compressibility on pressure pulsations induced by rotor-stator interaction (RSI) in hydraulic machinery, using the commercial CFD solver ANSYS-CFX. A pipe flow example with harmonic velocity excitation at the inlet plane is simulated using different grid densities and time step sizes. Results are compared with a validated code for hydraulic networks (SIMSEN). Subsequently, the solution procedure is applied to a simplified 2.5-dimensional pump-turbine configuration in prototype with different speeds of sound as well as in model scale with an adapted speed of sound. Pressure fluctuations are compared with numerical and experimental data based on prototype scale. The good agreement indicates that the scaling of acoustic effects with an adapted speed of sound works well. With respect to pressure fluctuation amplitudes along the centerline of runner channels, incompressible solutions exhibit a linear decrease while compressible solutions exhibit sinusoidal distributions with maximum values at half the channel length, coinciding with analytical solutions of one-dimensional acoustics. Furthermore, in compressible simulation the amplification of pressure fluctuations is observed from the inlet of stay vane channels to the spiral case wall. Finally, the procedure is applied to a three-dimensional pump configuration in model scale with adapted speed of sound. Normalized Pressure fluctuations are compared with results from prototype measurements. Compared to incompressible computations, compressible simulations provide similar pressure fluctuations in vaneless space, but pressure fluctuations in spiral case and penstock may be much higher.

A Study on the Sensor Module System for Real-Time Risk Environment Management (실시간 위험환경 관리를 위한 센서 모듈시스템 연구)

  • Cho, Young Chang;Kwon, Ki Jin;Jeong, Jong Hyeong;Kim, Min Soo
    • Journal of IKEEE
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    • v.22 no.4
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    • pp.953-958
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    • 2018
  • In this study, a portable detection system was developed that can detect harmful gas and signals simultaneously in an enclosed space of industrial sites and underground facilities. The developed system is a sensor module for gas detection, a patch type 1 channel small ECG sensor, a module for three-axial acceleration detection sensor, and a system for statistics. In order to verify the performance of the system modules, the digital resolution, signal frequency, output voltage, and ultra-small modules were evaluated. As a result of the performance of the developed system, the digital resolution was 300 (rps) and the signal amplification gain was 500 dB or more, and the ECG module was manufactured with $50mm{\times}10mm{\times}10mm$ to increase patch utilization. It is believed that the product of this research will be valuable if it is used as an IoT-based management system for real-time monitoring of industrial workers.