• Asian Pacific Journal of Cancer Prevention
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• v.16 no.12
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• pp.4825-4832
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• 2015

Incidence rates of nasopharyngeal carcinoma are high in Indonesia, Singapore and South-Eastern China. Chemoradiotherapy has been the standard regimen for locally advanced nasopharyngeal carcinoma according to guidelines from the National Comprehensive Cancer Network. Recently, advances in the management of nasopharyngeal carcinoma have transferred into better treatment outcomes. Most phase III clinical trials support the addition of concurrent chemotherapy to radiotherapy for the initial treatment of these patients. Studies evaluating effects and toxicity of concurrent chemotherapy with different regimens have been reported. However, the status of adding adjuvant chemotherapy or induction chemotherapy remains controversial. Recent studies have shown that adjuvant chemotherapy with two or three cycles may improve survival for nasopharyngeal carcinoma with stage N2-3 disease or with persistently detectable plasma EBV DNA after radiotherapy. This review examines the pertinent issues and latest studies concerning the management of loco-regionally advanced NPC, regarding concurrent chemotherapy, adjuvant chemotherapy, and induction chemotherapy in decades.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.12
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• pp.4821-4824
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• 2015

Gastric cancer is the 2nd most common cause of death among all cancers and is the 4th most common cancer in the world. The number of deaths due to gastric cancer is about 800,000 annually. Gastric cancer is more common in men as compared to women and is 3rd most common cancer after colorectal and breast cancers in women. A progressive rise in the incidence rate has been observed in females over the last 5 years. The highest incidence of stomach cancer is in China, South America and Eastern Europe. The incidence of gastric cancer has 20 fold variation worldwide. Global variation is linked by two factors which play important role in developing gastric cancer. One is infection with Helicobacter pylori and the $2^{nd}$ is diet. South Asia is a region with low risk, despite a high prevalence of H.pylori. Gastric carcinoma is common in southern region of India. Gastric cancer is more readily treated if diagnosed early. This study aims to provide awareness about gastric cancer as well as an updated knowledge about risk factors and epidemiology of gastric cancer in Pakistan.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.625-630
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• 2013

Background: Hardcore smoking is represented by a subset of daily smokers with high nicotine dependence, inability to quit and unwillingness to quit. Estimating the related burden could help us in identifying a high risk population prone to tobacco induced diseases and improve cessation planning for them. This study assessed the prevalence and associated factors of hardcore smoking in three South-East Asian countries and discussed its implication for smoking cessation intervention in this region. Materials and Methods: Global Adult Tobacco Survey (GATS) data of India, Bangladesh and Thailand were analyzed to quantify the hardcore smoking prevalence in the region. On the basis of review, an operational definition of hardcore smoking was adopted that includes (1) current daily smoker, (2) no quit attempt in the past 12 months of survey or last quit attempt of less than 24 hours duration, (3) no intention to quit in next 12 months or not interested in quitting, (4) time to first smoke within 30 minutes of waking up, and (5) knowledge of smoking hazards. Logistic regression analysis was carried out using hardcore smoking status as response variable and gender, type of residence, occupation, education, wealth index and age-group as possible predictors. Results: There were 31.3 million hardcore smokers in the three Asian countries. The adult prevalence of hardcore smoking in these countries ranges between 3.1% in India to 6% in Thailand. These hardcore smokers constitute 18.3-29.7% of daily smokers. The logistic regression model indicated that age, gender, occupation and wealth index are the major predictors of hardcore smoking with varied influence across countries. Conclusions: Presence of a higher number of hardcore smoking populations in Asia is a major public health challenge for tobacco control and cancer prevention. There is need of intensive cessation interventions with due consideration of contextual predictors.

• Strategy21
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• s.38
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• pp.250-286
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• 2015

The main purpose of this article is to provide an understanding on current maritime issues in the Northeast Asia, and thereby help formulating the right strategy for our national security. The article summarizes core arguments in the recently published 『The 21^st Century Maritime Strategies in the Northeast Asia: Dilemma between Competition and Cooperation』. It will help readers to comprehend historical backgrounds as well as recent updates related to maritime issues and strategies in the region. Also, readers may find guidance to conceive their own maritime strategies for the Republic of Korea. Currently, the U.S. is shifting its focus from Atlantic to Pacific, and increasing its naval presence in Asia-Pacific region. Meanwhile, the 21^st century China views the maritime interests as the top priority in its national security and prosperity. PLA Navy's offensive maritime strategies and naval building such as aircraft carriers and nuclear submarines are unprecedented. Japan is another naval power in the region. During the Cold War JMSDF faithfully fulfilled the mission of deterring Soviet navy, and now it is doing its job against China. Lastly, Putin has been emphasizing to build the strong Russia since 2000, and putting further efforts to reinforce current naval capabilities of Pacific Fleet. The keyword in the naval and maritime relations among these powers can be summarized with "competition and cooperation." The recent security developments in the South China Sea(SCS) clearly represent each state's strategic motivations and movements. China shows clear and strong intention to nationalize the islands in SCS by building artificial facilities - possibly military purpose. Obviously, the U.S. strongly opposes China by insisting the freedom of navigation(FON) in international waters as recent USS-Lassen's FON operation indicate. The conflict between China and the U.S. surrounding the SCS seems to be heading towards climax as Russia and Japan are searching for their own national interests within the conflict. Also, the neighboring small and middle powers are calculating their own economic and security interests. This is no exception for us in establishing timely strategies to maximize our own national security. Hopefully, this article leads the readers to the right direction.

• ALGAE
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• v.36 no.1
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• pp.13-24
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• 2021

The present-day genetic structure of macroalgal species reflects both geographical history and oceanic circulation patterns as well as anthropogenic introduction across native ranges. To precisely understand the genetic diversity and how the factors shape the current population structure of Gloiopeltis furcata sensu lato, we determined the mitochondrial 5' end of cytochrome c oxidase subunit I (COI-5P) sequences for 677 individuals sampled from 67 sites spanning almost the entire distribution range in Korea and Japan. Results from the phylogenetic analysis and haplotype distribution revealed eleven distinct lineages within G. furcata s.l. along the Korea-Japan coastal areas and displayed divergent phylogeographic patterns among lineages. Despite the closely related lineages distributed in same habitats as high rocky intertidal zone, they display different phylogeographic patterns among lineages. The populations from the south of Korea-Japan harbored the highest genetic diversity and unique endemism in comparison with other populations in the distribution range. This could be the evidence of southern refugia for G. furcata s.l. in the Northwest (NW) Pacific and the recent migration from native to introduced region. The reason is that an exceptional distribution pattern was found high genetic diversity in Hakodate of Japan where is the northern location in the NW Pacific. Our results imply the contemporary influence on the distribution due to current circulation pattern and anthropogenic effects. These phylogeographic findings provide the important insight into cryptic species diversity and the detailed distribution pattern of Gloiopeltis in the NW Pacific.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.3
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• pp.316-320
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• 2001

Sixteen growing crossbred Anglo-Nubian goats, 10-12 months old, pre-experimental average body weights of $18.3{\pm}0.28kg$ were randomly allotted to four diets to investigate the efficiency of utilisation of diets containing increasing levels of desiccated coconut waste meal (DCWM) in the tropical environment of Samoa, South Pacific region. The four diets were designated as 1, 2, 3 and 4. Diet 1 that has no DCWM served as the control, while diets 2, 3 and contained different levels of DCWM. Voluntary concentrate intake, growth rate, feed efficiency and nutrient digestibility coefficients were measured. Gross energy (GE) and organic matter (OM) values of the diets increased linearly with increase in the levels of DCWM in the diets. Voluntary concentrate intake decreased with increasing proportion of DCWM in the diets. Forage intake increased with increase in the levels of DCWM diets offered to the growing goats. Total voluntary feed intakes were statistical significant (p<0.05) and the goats on diet 4 had the least intake followed by those on diet 3. Goats an diets 1 and 2 were different in total feed intake but not at a significant level (p>0.05). Feed efficiency (FE) followed the trend of voluntary concentrate intake and daily live weight gains. Dry matter digestibility (DMD) was significantly different (p<0.05) among the goats offered the different diets. DMD improved with increasing levels of DCWM. The goats accepted all, the diets that were compounded with the different levels of dried DCWM and this seems to suggest that DCWM have no deleterious effects. However, the best level at which dried DCWM could replace brewers dried grains in the diets of growing goats is at 38.5% (diet II). Based on voluntary feed intake, live-weight gain and apparent nutrient digestibility coefficients of the goats it could be concluded that DCWM based diets merits further attention as a locally available feed source in ruminants nutrition in the Pacific Island countries where feed availability is seasonal.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.295-297
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• 2003

The coastal provinces of South China have been uniquely shaped by various tectonic events. During the midlate Mesozoic tectono-thermal event, the oblique subduction of the Paleo Kula-Pacific plate beneath the Eurasian plate has created a complicated tectonic setting for the whole region. However, the mechanism of this event is not completely understood. In this paper, we discuss the advantages of using LANDSAT TM satellite imagery over a small part of the region - the Mirs Bay Basin which is largely covered by dense vegetation and where limited outcrops is seen. The use of satellite imagery complements field mapping and the result shows a prominent sinistral offset along the eastern margin of the Mirs Bay Basin, which was not previously recognized on the ground.

• Journal of Environmental Science International
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• v.3 no.3
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• pp.229-239
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• 1994

By laying emphasis on the intermediate layer, water property distribution in the Northwest Pacific is studied using the hydrographic data obtained by Japan Meteorologica] Agency in the period from 1960 to 1986. The scattering of water type in T-S diagram is relatively small in the Kuroshio Region. Both the envelopes of saline side and of fresh side of the scattered data points shifts gradually from saline side to fresh side as the observation line moves from southwest to northeast. In the Mixed Water Region, the scattering of water type increases rapidly as the observation line moves north; The envelope of fresh cold side moves towards fresh cold side much faster than that of same side. The thermosteric anomaly value at the salinity minimum decreases as the observation line moves from north to south or southwest. This suggests that the water does not advect along the salinity minimum layer, but that the salinity minimun layer is understood as a boundary of two different waters aligned vertically. We defined the typical water masses for the Oyashio Water and the Kuroshio Water. The water mass below the salinity minimum layer may be created by isopycnal mixing of these two water masses with a fixed mixing rate. While, the water mass above the salinity minimum cannot be created simply by isopycnal mixing. The salinity minimum layer may be eroded from upper side due to active mixing processes in the surface layer, while the water of the salinity minimum layer moves gradually southward. This appears to give an explanation why the thermosteric anomaly value at salinity minimum decreases towards south.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6965-6969
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• 2013

Background: Tobacco consumption has been identified as the single biggest cause of inequality in morbidity and mortality. Understanding pattern of socioeconomic equalities in tobacco consumption in India will help in designing targeted public health control measures. Materials and Methods: Nationally representative data from the India Global Adult Tobacco Survey (GATS) conducted in 2009-2010 was analyzed. The survey provided information on 69,030 respondents aged 15 years and above. Data were analyzed according to regions for estimating prevalence of current tobacco consumption (both smoking and smokeless) across wealth quintiles. Multiple logistic regression analysis predicted the impact of socioeconomic determinants on both forms of current tobacco consumption adjusting for other socio-demographic variables. Results: Trends of smoking and smokeless tobacco consumption across wealth quintiles were significant in different regions of India. Higher prevalence of smoking and smokeless tobacco consumption was observed in the medium wealth quintiles. Risk of tobacco consumption among the poorest compared to the richest quintile was 1.6 times higher for smoking and 3.1 times higher for smokeless forms. Declining odds ratios of both forms of tobacco consumption with rising education were visible across regions. Poverty was a strong predictor in north and south Indian region for smoking and in all regions for smokeless tobacco use. Conclusions: Poverty and poor education are strong risk factors for both forms of tobacco consumption in India. Public health policies, therefore, need to be targeted towards the poor and uneducated.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.23 no.4
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• pp.12-21
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• 2015

Due to the influence of Han-la Mountain which is located at the center of Jeju Island, a radar blind sector has been appearing in the south-east, low-altitude area of Jeju Island. Thus, the region is perilous for aircraft using surveillance in this area with the existing radar equipment that is currently available. In addition, as the popularity for domestic leisure aviation is on the rise, the safety in low-altitude area should be guaranteed. Where not only IFR flights but also VFR flights are mainly used. Therefore, immediate measures to the present state of radar blind sector in Jeju Island should be taken into serious account. Regarding the circumstances, this study's purpose is to help secure the aviation safety in Jeju region by analyzing the current air traffic surveillance system in Jeju Island and comprehending its vulnerable factors. Moreover, this study compares secondary radar surveillance system, ADS-B and MLAT(Multilateration) system with factors based on the guidance materials from ICAO Asia and Pacific region office to suggests an adequate surveillance technology considering the regional characteristics of Jeju.