• Title/Summary/Keyword: Sophora Japonica Linne Seed Extract (SE)

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Genotoxicity studies of Sophora Japonica Linne Seed Extract(SE)

  • Min, Soo-Jin;Zheng, Mei-Shu;Kim, Su-Hyon;Kang, Jong-Koo;Kim, Kuk-Hwan;Sik Hwangbo;Kwon, Suk-Hyung
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.10b
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    • pp.119-119
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    • 2003
  • The objective of this study was to determine genotoxic potential of Sophora Japonica Linne Seed Extract(SE). The bacterial reverse mutation test set the treatment levels of SE at 0, 312.5, 625, 1250, 2500, 5000 $\mu\textrm{g}$/plate using Salmonella typhimurium strains (TA1535, TA1537, TA98, TA100) and Escherichia coli WP2uvrA(pKM101). (omitted)

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13-Week Oral Gavage Toxicity with Sophora Japonica Linne Seed Extract in Sd Rats

  • Lee, Hye-yeong;Kim, Sun-hee;Park, Sun-hee;Kang, Seong-kwi;Lee, Jong-sung;Kwon, Suk-hyung;Sik Hwangbo;Kim, Kuk-hwan;Kang, Jong-koo
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.10b
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    • pp.132-132
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    • 2003
  • In this GLP study, 4 study groups of 12 Sprague-Dawley (SD) rats/sex were given vehicle, or 1,000, 1,500, or 2,000 mg/kg/day Sophora Japonica Linne Seed Extract (SE) for 13 weeks. Standard endpoints in this study included mortality, clinical observations, body weight, food and water consumption, ophthalmoscopic examination, urinalysis, hematology, serum biochemistry, organ weights, gross anatomic pathology and histopathology.(omitted)

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