• Proceedings of the KSR Conference
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• 2003.10c
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• pp.236-246
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• 2003

This paper is implemented a control algorithm in order to be stable and minimized to entire train traffic system at delayed case. Signal ing system is described wi th algebraic equations given for train headway, Discrete-event simulation principles are reviewed and a demonstration block signaling model using the technique is implemented. Train congestion at station entrance for short headway operation is demonstrated and the propagation of delays along a platform of trains from any imposed delay to the leading train is also shown. A rail way signaling system is by nature a distributed operation with event triggered at discrete intervals. Although the train kinematic variables of position, velocity, and acceleration are continually changing, the changes are triggered when the trains pass over section boundaries and arrive at signals and route switches. This paper deals with linear-mode1ing, stability and optimal control for the traffic on such metro line of the model is reconstructed in order to adapt the circuits. This paper propose optimal control laws wi th state feedback ensuring the stability of the modeled system for circuits. Simulation results show the benefit to be expected from an efficient traffic control. The main results are summarized as follows: 1. In this paper we develop a linear model describing the traffic for both loop lines, two state space equations have been analyzed. The first one is adapted to the situation where a complete nominal time schedule is available while second one is adapted when only the nominal time interval between trains is known, in both cases we show the unstability of the traffic when the proceeding train is delayed following properties, - They are easily implemented at law cost on existing lines. - They ensure the exponetial stability of loop system. 2. These control laws have been tested on a traffic simulation software taking into the non-linearites and the physical constraints on a metro line. By means of simulation, the efficiency of the proposed optimal control laws are shown.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.38 no.1
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• pp.44-54
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• 2001

In this paper, a novel test method is proposed to detect the hard and soft fault in analog circuits. The proposed test method makes use of the offset voltage, which is one of the op-amps characteristics. During the test mode, CUT is modified to unit gain op-amps with feedback loop. When the input of the op-amp is grounded, a good circuit has a small offset voltage, but a faulty circuit has a large offset voltage. Faults in the op-amp which cause the offset voltage exceeding predefined range of tolerance can be detected. In the proposed method, no test vector is required to be applied. Therefore the test vector generation problem is eliminated and the test time and cost is reduced. In this note, the validity of the proposed test method has been verified through the example of the dual slope A/D converter. The HSPICE simulations results affirm that the presented method assures a high fault coverage.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.27 no.4
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• pp.255-263
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• 2014

In this paper, seismic fragility analysis of lightning arrester is performed using capacity spectrum method(CSM). Since seismic fragility analysis of structure with many structural members is required to calculate many inelastic responses for several tens or hundreds of ground motions, simple method such as CSM is more appropriate than response history analysis(RHA). In general, accuracy of seismic response evaluated by CSM is less than that by RHA. In order to increase accuracy of CSM, equivalent SDOF method and performance point calculation technique are applied to CSM. Seismic fragility method proposed by Shinozuka et al. is used. In order to evaluate site effect of ground motions on seismic fragility, 60 different site classification earthquakes are selected as input ground motions. From the seismic fragility curves of lightning arrester evaluated by CSM and RHA, it can be observed that the seismic fragility curves evaluated by CSM are very similar to those by RHA. Also, it can be observed that main seismic failure mode of lightning arrest is bushing breakage.

• Journal of Dental Rehabilitation and Applied Science
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• v.16 no.3
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• pp.237-245
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• 2000

The purpose of this study was to compare the fracture strength of the IPS Empress ceramic crown according to the incisal depth(2.0mm, 2.5mm, 3.0mm) and axial inclination($4^{\circ}$, $8^{\circ}$, $12^{\circ}$) of the upper central incisor. After 10 metal dies were made for each group, the IPS Empress ceramic crowns were fabricated and each crown was cemented on each metal die with resin cement. The cemented crowns mounted on the testing jig were inclined 30 degrees and a universal testing machine was used to measure the fracture strength. The results were : 1. The fracture strength of the ceramic crown with 2.5mm depth and $8^{\circ}$ inclination was the highest(965N). Crowns of 2.0mm depth and $4^{\circ}$ inclination had the lowest strength(713N). There were no significant differences of the fracture strength by axial inclination in same incisal depth group. 2. The fracture mode of the crowns was similar. Most of fracture lines began at the loading area and extended through proximal surface perpendicular to the margin irrespective of incisal depth. There had correlation between fracture strength and fractured surface area.

• Molecules and Cells
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• v.41 no.6
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• pp.545-552
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• 2018

Spleen tyrosine kinase (SYK) is a cytosolic non-receptor protein tyrosine kinase. Because SYK mediates key receptor signaling pathways involving the B cell receptor and Fc receptors, SYK is an attractive target for autoimmune disease and cancer treatments. To date, representative oral SYK inhibitors, including fostamatinib (R406 or R788), entospletinib (GS-9973), cerdulatinib (PRT062070), and TAK-659, have been assessed in clinical trials. Here, we report the crystal structures of SYK in complex with two newly developed inhibitors possessing 4-aminopyrido[4,3-D]pyrimidine moieties (SKI-G-618 and SKI-O-85). One SYK inhibitor (SKI-G-618) exhibited moderate inhibitory activity against SYK, whereas the other inhibitor (SKI-O-85) exhibited a low inhibitory profile against SYK. Binding mode analysis indicates that a highly potent SYK inhibitor might be developed by modifying and optimizing the functional groups that interact with Leu377, Gly378, and Val385 in the G-loop and the nearby region in SYK. In agreement with our structural analysis, one of our SYK inhibitor (SKI-G-618) shows strong inhibitory activities on the ${\beta}$-hexosaminidase release and phosphorylation of SYK/Vav in RBL-2H3 cells. Taken together, our findings have important implications for the design of high affinity SYK inhibitors.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2007.11a
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• pp.277-282
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• 2007

Construction process works in sequence order and there are many different software for managing project and activity. So, there are many limitations such as in the stage of activity data loss can occur, in each stage concurrent cannot operate in construction industry. In order to solve these problem, agents have to cooperate each other and they need to share of data. Therefore, the purpose of this paper is to develop a process model and the process model will be use in the future to make Construction Project Life-Cycle Management based on concept of PLM(Product Life cycle Management) in the manufacturing industry, CE(Concurrent Engineering) and BlM(Building Information Modeling)

• Environmental Mutagens and Carcinogens
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• v.25 no.4
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• pp.157-160
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• 2005

Antibiotic resistance of bacteria in the biofilm mode of growth contributes to the chronicity of infection and disease. The penetration of antibiotic, through biofilm developed in an itt vitro model system was investigated. Antibiotic resistant bacteria (E. coli) were obtained from Culture Collection of Antibiotic Resistant Microbes. Ca-alginate bead used as simulated biofilm and a cell entrapment test using compressed air were experiment for the improvement cell viability. Antibiotic susceptibilities though biofilms was measured by assaying the concentration of antibiotic that diffused through the biofilm to minimal inhibition concentration (MIC). Survival of immobilized cells were reduced as compared to free cells. In case of antibiotic susceptible E. coli reduced continuously, but antibiotic resistant E. coli kept up survival rate constantly. Survival was showed after exposed to the antibiotics that the more treated antibiotic resistant E. coli and low concentration of antibiotics) the more survived.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.2
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• pp.959-962
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• 2005

Recently, business integration and interoperability of between the heterogeneous applications are requested by rapid growth of web. Web Services that self-contained for platform and programming language is appeared used to XML of standard data format. Such amid Fast Web Services attract attention at fields necessary to bring rapid communication like Mobile and RFID. In this paper, we inquired about ASN.1 of ITU-T and IS0/IEC standard that a central role of data transform. And we studied encoding process of between ASN.1 and XML for transform SOAP massage of a massage transfer mode of Web Services to binary data.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.50 no.12
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• pp.639-647
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• 2001

We present an integrated optical microswitch, composed of silicon waveguides, gold-coaled silicon micromirrors, and electrostatic contact actuators, for applications to the optical signal transceivers. For a low switching voltage, we modify the conventional curled electrode microactuator into a electrostatic microactuator with touch-down beams. We fabricate the silicon waveguides and the electrostatically actuated micromirrors using the ICP etching process of SOI wafers. We observe the single mode wave propagation through the silicon waveguide with the measured micromirror loss of $4.18\pm0.25dB$. We analyze major source of the micromirror loss, thereby presenting guidelines for low-loss micromirror designs. From the fabricated microswitch, we measure the switching voltage of 31.74V at the resonant frequency of 6.89kHz. Compared to the conventional microactuator, the present contact microactuator achieves 77.4% reduction of the switching voltage. We also discuss a feasible method to reduce the switching voltage to 10V level by using the electrode insulation layers having the residual stress less than 30MPa.

• Journal of the Korean Society of Combustion
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• v.18 no.2
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• pp.32-41
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• 2013

This study presents both experimental and numerical investigation of ignition delay time of n-heptane and n-butanol binary fuel. The $O_2$ concentration in the mixture was set to 9-10% to make high exhaust gas recirculation( EGR) rate condition which leads low NOx and soot emission. Experiments were performed using a rapid compression machine(RCM) at compressed pressure 20bar, several compressed temperature and three equivalence ratios(0.4, 1.0, 1.5). In addition, a numerical study on the ignition delay time was performed using CHEMKIN codes to validate experimental results and predict chemical species in the combustion process. The results showed that the ignition delay time increased with increasing the n-butanol fraction due to a decrease of oxidation of n-heptane at the low temperature. Moreover, all of the binary fuel mixtures showed the combustion characteristics of n-heptane such as cool flame mode at low temperature and negative-temperature-coefficient(NTC) behavior. Due to the effect of high EGR rate condition, the operating region is reduced at lean condition and the ignition delay time sharply increased compared with no EGR condition.