• 동의생리병리학회지
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• 제26권6호
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• pp.980-982
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• 2012

Metastasis to the pancreas from extra-pancreatic primary cancers are rare; they commonly present as a manifestation of widespread disease and rarely as an isolated mass of the pancreas. Examinations showed a pancreatic tumor infiltrating the pancreas tail portion and an endoscopic ultrasound guided percutaneous biopsy proved that the lesion was metastatic from the lung carcinoma. Most metastatic cases of the pancreas tend to be discovered in patients with widely disseminated malignant disease. In addition, patients with pancreatic metastasis are often asymptomatic, the metastatic lesions are found incidentally, and are misdiagnosed as primary pancreatic tumors. This report that patient undergoing chemotherapy for a small cell lung cancer, who 1 year and 3 months later, accidentally diagnosed of solitary pancreas metastasis and confirmed histology by needle biopsy using endoscopic ultrasound.

• Tuberculosis and Respiratory Diseases
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• 제67권1호
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• pp.42-46
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• 2009

저자들은 복통으로 내원한 환자에서 발견된 췌장 결절이 수술을 통하여 비소세포폐암의 단일성 췌장전이로 확진 되었던 드문 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Investigative Magnetic Resonance Imaging
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• 제18권1호
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• pp.64-69
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• 2014

췌장에 생기는 종양 중에 adenosquamous carcinoma는 드물지만, 예후가 좋지 않으며 더 흔한 adenocarcinoma보다 다른 곳으로 전이할 확률이 높다. 이 증례 보고는 pancreas에 생긴 adenosquamous cell carcinoma와 liver로 전이한 병변이 서로 다른 영상소견을 보이는 드문 예로, 기존의 문헌들을 참고해 pancreas에 생기는 드문 질병인 adenosquamous cell carcinoma에 대한 이해를 돕기 위함이다.

• Journal of Digestive Cancer Research
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• 제6권2호
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• pp.73-77
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• 2018

췌장암으로 진단된 70세 여자 환자가 유문보존 췌십이지장 절제술 및 5-fluorouracil 동시항암화학요법으로 치료받았다. 수술 후 병리학적으로 pT3N0 (stage IIA)의 췌장선암이 확진되었다. 14개월 뒤 복부 전산화단층촬영에서 10 mm 크기의 단일 간 재발 병소가 간 3번 분엽에서 발견되었다. Gemcitabine 12주기 및 capecitabine plus oxaliplatin 9주기 항암치료를 시행했으나 전이병소는 27mm로 크기가 증가하였다. 이에 간 3번 분엽의 종양절제술을 시행하였다. 종양절제술 시행 25개월 뒤 흉부 전산화단층촬영에서 23 mm 크기의 단일 공동성 폐결절이 발견되었고, 조직검사에서 전이성 선암으로 확인되었다. 환자는 두 차례의 정위적 체부 방사선 치료 후 질병의 진행 없이 진단 후 6년 이상 장기 생존 중이다. 본 증례를 통해 수술 후 단일 간 전이 혹은 폐 전이가 발견된 일부 환자들에서 수술적 절제를 비롯한 국소 치료가 장기생존에 도움이 될 것으로 사료된다.

• Journal of Gastric Cancer
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• 제13권3호
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• pp.185-187
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• 2013

Neurofibromas are benign tumors that originate from the peripheral nerves, including neurites and fibroblasts. Generally, a solitary neurofibroma is located in the skin and rarely in other places. A 72-year-old female suffered from epigastric discomfort for 2 months. Endoscopic findings showed an early gastric cancer type IIc at the antrum. Abdominal computed tomography revealed early gastric cancer with a 1.6 cm-sized metastatic node posterior to the duodenum. Laparoscopic assisted distal gastrectomy and retro-pancreatic dissection were performed uneventfully. Histological examination revealed gastric adenocarcinoma, invading the mucosa without nodal metastasis, and a neurofibroma. Herein, we present a case of a gastric cancer patient with a solitary retroperitoneal neurofibroma which mimicked a distant metastatic node.

• 한국간담췌외과학회지
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• 제27권2호
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• pp.180-188
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• 2023

Backgrounds/Aims: The present study looked at the role of radical surgery in gallbladder cancers (GBC) with limited metastatic disease. Methods: The retrospective observational study was conducted to screen the database from 1st January 2010 to 31st December 2019. Patients of GBC found to have low-volume metastatic disease upon surgical exploration were included. Results: Of the 1,040 patients operated for GBC, 234 patients had low-volume metastatic disease (microscopic disease in station 16b1 node or N2 disease isolated port-site metastases, or low burden peritoneal disease with deposits less than 1 cm, in adjacent omentum or adjacent diaphragm or Morrison's pouch or a solitary discontinuous liver metastasis in adjacent liver parenchyma) detected intraoperative. Of these, 62 patients underwent radical surgery for R-0 metastatic disease followed by systemic therapy, while the remaining 172 patients did not undergo radical surgery and were given palliative systemic chemotherapy. Patients who underwent radical surgery had significantly superior overall survival (19 months versus 12 months, p < 0.01) and superior progression-free survival (10 months versus 5 months, p < 0.01) when compared to the rest. This difference in survival was more significant amongst patients when operated on after neoadjuvant chemotherapy. Regression analysis showed that a sub-group of patients with incidental GBC with limited metastases showed more favorable outcomes with radical surgery. Conclusions: Authors suggest a possible role for radical treatment of advanced GBC with a limited metastatic burden. Neoadjuvant chemotherapy can be used for preferentially selecting patients of favorable disease biology for curative treatment.