• 대한기관식도과학회지
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• 제8권1호
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• pp.87-91
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• 2002

Solitary fibous tumor of pleura is a rare and slow vowing neoplasm. The histogenesis of this tumor is thought as mesenchymal origin by immunohistochemical and ultrastructural bases. This case report is of a 69-year-old female who presented severe dyspnea and orthopnea with long-term history. Preoperative chest X-ray an chest CT revealed huge and hemithorax-occupying heterogenous mass and cardiomegaly. She underwent surgical resection and a 22 X 18 X 10 cm sized visceral pleural based mass was evacuated. Histologic findings of tumor showed patternless proliferation in a fibrocollagenous and well vasculized stroma. Immnohistochemical staining revealed strong positive in CD34, that are compatible with solitary fibrous tumor of pleura. The patient was discharged without any complications and no evidence of recurrence was found after 2 years.

• 대한세포병리학회지
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• 제2권2호
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• pp.134-141
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• 1991

Localized or solitary fibrous tumor (SFT) of the pleura has been classified as a type of mesothelioma, arising from the submesothelial connective tissue cells. The preoperative diagnosis of the tumor at the cytologic or histologic level is very important for the proper handling of the lesion. This preoperative diagnosis is now possible by means of the advance in the transthoracic fine needle aspiration biopsy (FNA) techniques and in the very experience of the cytopathologists. We describe FNA cytologic feature of two cases of SFT arising from the pleura. Cytologic, histologic, immunohistochemical, and electron microscopic characteristics of pleural SFT are discussed. The tumor cells of SFT are spindle or oval in shape with a variable amount of cytoplasm. They are arranged in irregular trabeculae intimately associated with capillaries. A unique cytologic feature observed in this tumor is that thick, eosinophilic, amorphous collagen bundles are scattered between tumor cells.

• 대한세포병리학회지
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• 제12권2호
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• pp.111-115
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• 2001

Solitary fibrous tumor on the pleura is rare but should be included in the differential diagnosis on a peripheral pulmonary nodule. Cytologic features of solitary fibrous tumor of the pleura is not familar to the pathologist and may be misdiagnosed as malignancy. We report fine needle aspiration cytologic(FNAC) findings of a case of solitary fibrous tumor misdiagnosed as adenocarcinoma in a 48-year-old woman. The FNAC displayed a mixture of bland-looking spindle cells and clusters of epithelioid cells, which have hyperchromatic nuclei with prominent nucleoli. The helpful finding to distinguish It from other circumscribed benign and malignant lesions is the presence of fibromyxoid matrix admixed with blood vessels and thin collagen fibers. Familiarity with these features is essential to avoid misdiagnosis and overtreatment.

• Journal of Chest Surgery
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• 제27권1호
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• pp.76-80
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• 1994

A solitary fibrous tumor in the pleura has been reported occasionally, but extremely rare in themediastinum. The histogenesis of this tumor has been still in controverse, but recent studies paid attention to it a mesenchymal origin by the immunohistochemical and ultrastructural bases. A few cases, reported in the literature, suggest that the mediastinal solitary fibrous tumor occurs more commonly in adult and shows slightly higher incidence in women. Its aggressive behavior such as recurrence rate and distant metastasis, is more prominant than reported in solitary fibrous tumor of the pleura. No single histologic feature allows an assumption definite prognosis. Surgical resection of this tumor is usually curative although the recurrence or distant metastasis are reported in about half of the patients. This report is a case of solitary fibrous tumor in the mediastinum in a 16-year-old female patient.She underwent surgical resection and her postoperative result was satisfactory.

• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.338-344
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• 2021

Solitary fibrous tumors (SFT) are rare mesenchymal tumors that most commonly develop in the pleura; they rarely involve the diaphragm. MRI has not been widely used to evaluate SFTs of the thoracic cavity, though it may be highly useful in assessing local invasion, predicting malignant potential, and helping in the differential diagnosis. However, MRI findings of malignant SFTs of the diaphragmatic pleura have been described in only two cases. We report a rare case of a malignant solitary fibrous tumor of the diaphragmatic pleura in an 82-year-old man. We describe the clinical and characteristic imaging features, including computed tomography, conventional MRI, and diffusion-weighted imaging. Contrast-enhanced MRI is more accurate than is CT in identifying the origin of SFTs, predicting whether they ae benign or malignant, and assessing local invasion. This imaging modality proved helpful in deciding on the treatment strategy for these rare tumors.

• Journal of Chest Surgery
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• 제29권7호
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• pp.798-801
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• 1996

흉막에 발생한 고릴성 섬유종은 비교적 회귀한 질환으로 알려져 있으며, 대부분 장측 흉막에서 발생하고 벽측 홍막에서 발생되는 경우는 매우 드물다. 저자들은 48세 여자환자에서 우흉곽내 벽측 흉막에서 발생한 거대 고립성 섬유종 1례를 수술 치험하였다. 환자는 10개월전 부터 발생한 호흡곤란이 주증상이었고, 술전 흉부전산화 단층될영상 우측 폐실질을 주변으로 밀어내는 이종의 종괴형태를 보였다. 수술 소견상 종괴는 피낭에 싸여 있었고, 벽측 흉막에서 기 시하였다. 절제된 종괴의 크기는 20cmX15cmX11cm였고, 무게는 2200gm에 이르렀다. 환자는 합병증없이 퇴원하였으며 술후 6개월 간 추적 관찰하였으나 재발의 소견없이 양호한 상태를 보이고 있다.

• Journal of Chest Surgery
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• 제29권12호
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• pp.1385-1391
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• 1996

흉막의 고립성 섬유성 종양은 과거 중피종의 한 형태로 알려져 있으며 중피종과 흔돈하여 쓰여 왔으나 최근에는 중피하에 존재하는 미분화 중배엽성 기원의 섬유세포에서 기원하고 있는 종양으로 해석된다. 환자는 65세 여자로 우측흉통과기침 및 호흡곤란을 주소로 본원에 입원하여 흉부 방사선 및 전산화 단층 촬영상 우측 흉강내에 고형성 종괴가 발견되었다. 수술소견상 종괴의 크기와 무게는 12$\times$12$\times$6mm, 400mm 이었으며, 폐 실질내로 침윤하였고 세기관지 내강을 따라 성장한 부분이 관찰되었다. 또한 종괴는 횡경막과 벽측 흉막 및 폐실질에 다발성으로 전이 되어 있었다. 병리학적으로, 종괴는 세포밀도가 높았고, 판상배열을 보이는 등글거나 난원형 또는 짧은 방추형의 세포로 이루어졌으며, 10배의 고배율 시야에서 3개의 유사분열이 관찰되었다. 면역조직화학 염색상 vimentin과 actin에 미만성 강양성 반응을 보였고 전자현미경적으로 조면 세포질내세망이 풍부하며 세포접합부나 미세응모는 관찰되지 않아서 악성 고립성 섬유성 종양에 합당하였다. 본 교실에서는 흉막에 발생한 악성 고립성 섬유성 종양을 경험하였기에 문헌 고찰과 함께 보고한다.

• 대한두경부종양학회지
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• 제15권2호
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• pp.243-245
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• 1999

Solitary fibrous tumors are commonly arise in the pleura and less commonly in extrapleural sites. In head and neck area, solitary fibrous tumors can occur in nose, paranasal sinus, soft palate, epiglottis, thyroid, parotid and submandibular gland. To our knowledge, this is the 5th case of solitary fibrous tumor arising from the parotid gland in English literature. We report a case of solitary fibrous tumor occurred in the superficial lobe of right parotid gland which was successfully treated by superficial parotidectomy with preservation of the facial nerve.

• 대한두개안면성형외과학회지
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• 제18권3호
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• pp.218-221
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• 2017

A solitary fibrous tumor is a relatively uncommon neoplasm that usually occurs in the pleura but occurs extremely rarely in the oral cavity. Reported herein is a rare case of a solitary fibrous tumor in the buccal cheek mucosa. A 50-year-old man visited the authors' hospital due to a buccal cheek mass whose size had increased. Excisional biopsy was done under local anesthesia. After the excisional biopsy, the patient was diagnosed to have a solitary fibrous tumor. In immunohistochemistry, the patient's solitary fibrous tumor was characterized by the expression of CD34 and CD99 on the neoplastic cells, and negativity for Bcl-2 and S-100. No recurrence or complication occurred for a period of 5 years. The growth of a primary solitary fibrous tumor in the buccal cheek mucosa is extremely rare and has been rarely reported in the South Korean medical literature. A solitary fibrous tumor must be distinguished from other spindle cell tumors. Presented herein is a case of primary solitary fibrous tumor in the buccal cheek mucosa. The relevant literature is briefly reviewed.

• Journal of Chest Surgery
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• 제35권7호
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• pp.568-572
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• 2002

우리는 단순 흉부 방사선 촬영에서 우연히 발견한 47세 여자의 횡격흉막에서 발생한 양성 고립성 섬유성 종양 1례를 보고한다. 단순 흉부 방사선 촬영, 복부 초음파 검사, 전산화 단층 촬영과 자기공명영상으로 주변과 경계가 분명한 다엽성의 흉막 섬유성 종양으로 진단하였다. 우측 개흉 수술시 종괴는 대부분 유착이 없었으나 $5{\times}4$cm 정도의 횡격막 중앙부와 유경으로 붙어 있었다. 붙어 있는 횡격막과 함께 종괴를 완전히 절제하였다. 종양은 $23.5{\times}13.5{\times}8.0$cm 크기였으며, 병리조직학 진단은 양성 섬유성 종양이었고 함께 절제된 횡격막에는 종양세포가 없었다.