• YAKHAK HOEJI
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• v.47 no.5
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• pp.325-330
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• 2003

Solanum melongena L. (Solanaceae) has anti-oxidant, analgesic, and hypolipidemic effects. We previously showed that Solanum melongena (SM) aqueous extract inhibits mast cell-mediated allergic reactions. The activation of protease-activated receptor-2 (PAR-2) induces acute inflammation in rat hindpaw. In the present study, we investigated the effects of the SM aqueous extract on mouse paw edema induced by PAR2 agonists. Trypsin or trans-cinnamoyl-LIGRLO-NH$_2$ (tc-NH$_2$), PAR-2 agonists, was injected into the hind paw of mice to induce paw edema. SM aqueous extract (1, 5, 10, and 100 mg/kg) was orally administered 1 hr before induction of paw edema. SM aqueous extract (5, 10, and 100 mg/kg) significantly inhibited both paw edema and vascular permeability in the dose-dependent manner. Furthermore, SM aqueous extract (10 mg/kg) significantly inhibited PAR-2 agonist-induced myeloperoxidase (MPO) activity and tumor necrosis factor (TNF)-$\alpha$ expression in paw tissue compared to that of saline. These results suggest that SM aqueous extract may be useful for treatment of PAR-2-mediated inflammation.

• Korean Journal of Pharmacognosy
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• v.41 no.2
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• pp.89-93
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• 2010

Korean folk medicine 'GaJi' has been used to treat a boil, cough, mushroom poisoning and stomach cancer. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'GaJi', the morphological and anatomical characteristics of the stems of Solanum species growing in Korea, i.e. S. japonense Nakai, S. lyratum Thunb., S. melongena L., S. nigrum L. were compared. As a result, it was determined that GaJi was the stem of Solanum melongena L.

• Archives of Pharmacal Research
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• v.28 no.6
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• pp.657-659
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• 2005

A new biflavonol glycoside named as solanoflavone (1) was isolated from aerial part of Solanum melongena. The chemical structure was elucidated as isorhamnetin-3-O-$\beta$-D-glucopyranoside-(4'$\to$O$\to$4"')-galangin-3"-O-$\to$-D-glucopyranoside on the basis of physicochemical and spectroscopic methods, including 2D NMR spectral techniques.

• Journal of Applied Biological Chemistry
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• v.59 no.2
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• pp.103-106
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• 2016

The leaves of eggplant (Solanum melongena L.) were extracted with 80 % aqueous MeOH, and the concentrated extract was partitioned with n-hexane, EtOAc, n-BuOH, and water fractions. From the n-BuOH fraction, five compounds were isolated through the repeated silica gel, octadecyl silica gel, and Sephadex LH-20 column chromatographies. On the basis of physic-chemical and spectroscopic data including mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance, they were identified to be caffeic acid (1), chlorogenic acid (2), cryptochlorogenic acid (3), panasenoside (4), and (6R,7E,9R)-4,7-megastigmadien-3-one-9-${\beta}$-${\small{D}}$-glucopyranoside (5). Compounds 3 and 4 were isolated for the first time from the leaves of S. melongena L. in this study.

• Mycobiology
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• v.33 no.3
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• pp.163-165
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• 2005

In April 2002 and 2003, soft rot on fruit of eggplant (Solanum melongena) caused by Choanephora cucurbitarum was observed in the experimental fields at Gyeongnam Agricultural Research and Extension Services in Korea. The disease began with water-soaking and dark-green lesions, and then the infected tissues were rapidly rotten. Sporangium was subglobose in shape and sized $40{\sim}130\;{\mu}m$. Monosporous sporangiola were elliptic, fusiform or ovoid, brown in color, and measured as $12{\sim}20\;{\times}\;6{\sim}14\;{\mu}m$. Sporangiospores having three or more appendages were elliptic, fusiform or ovoid in shape, dark brown or brown in color, and sized $14{\sim}20\;{\times}7{\sim}16\;{\mu}m$. The fungus grew well on potato dextrose agar between 15 and $40^{\circ}C$ and its optimum growth temperature was $30^{\circ}C$. Based on morphological characteristics, the causal fungus of the fruit soft rot of eggplant was identified as C. cucurbitarum. This is the first report on the soft rot of S. melongena caused by C. cucurbitarum in Korea.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.1
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• pp.133-137
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• 2001

The antioxidant activitiesof methanol extracts of twenty one vegetables were tested using the method of 1,1-diphenyl-2-picryl hydrazyl (DPPH) reactivity and TBARS substance assay in vitro. The methanol extracts of the leaves from three plants such as Aster scaber, Chrysanthemum coronarium, Petasites japonicus were found to be th most effective on DPPH radical scavenging activity. The next effective ones were the leaves of Capsicum annuum, the peels of Ipomoea batatas and Solanum tuberosum, the stems and leaves of Ipomoea batatas, the levels of Solanum melongena, the fruits of Solanum melongena, the green fruits (seed) of Capsicum ammuum in order, and the others did not show a considerable activity. When tested on lipid peroxidation using a lipid peroxidation generation system mediated by $H_{2}O_{2}/Fe^{2+}$ in rat liver homogenates. the peels of Cucumis melo, the leaves and the fruits of Solanum melongena, of Solanum melongena, The levels of Aster scaber and Chrysanthemum coronarium, the stems and leaves of Ipomoea batatas and the peels of Ipomoea batatas were found to exhibit a good protective activity against lipid peroxidatian in the order of effectiveness.

• Current Research on Agriculture and Life Sciences
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• v.5
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• pp.19-26
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• 1987

The experiments were conducted to identify several factors affecting isolation and culture of mesophyll protoplasts in Solanum melongena var. fructualbo. Higher viable plotoplasts were obtained, when isolated in 1.5% macerozyme, 0.2% macerozyme, 0.6M mannitol, 0.01M MES, 0.2% BSA containing solution adjusted to pH 6.3 for 4 hours. One hour plasmolysis of the material before digestion of leaf tissue was effective for protoplast yield and viability. The method of washing and purification of crude protoplasts, ESS process with 0.7M mannitol and 0.6M sucrose solution. was the best way to get purified protoplasts with viability. As isolated protoplasts were cultured in 8P-KM medium at a density of $2.5{\times}10^4/ml$, the cells were enlarged after 3 to 5 days from culture, subsequently the cells were divided and resulted in colonies.

• BMB Reports
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• v.30 no.2
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• pp.150-156
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• 1997

Tyrosinase was purified from Solanum melongena by ammonium sulfate precipitation, Sephadex G-150 and DEAE-Sephacel column chromatography. The molecular weight of the purified tyrosinase was approximately 88,600 daltons with 805 amino acid residues. The amino acid composition showed the characteristic high contents of glycine, glutamic acid and serine residues. The enzyme had high substrate specificity towards (+)-catechin. The $K_m$, value for L-DOPA was 20.8 mM. L-ascorbic acid, ${\beta}-mercapto-ethanol$, sodium diethyldithiocabamate, KCN and $NaN_3$ had strong inhibitory effects on enzyme activity. Sodium diethyldithiocabamate was a competitive inhibitor of the enzyme with a $K_i$ value of $5.2{\times}10^{-2}\;mM$. The optimum pH of the enzyme was 9.0 and the optimum temperature was $65^{\circ}C$ with L-DOPA as a substrate. In addition, the activity was enhanced by addition of $Ca^{+2}$ or $Cu^{+2}$, but decreased in the presence of $Fe^{2+},Fe^{3+}$ and $Zn^{2+}$ ions.

• Korean Journal of Agricultural Science
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• v.38 no.4
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• pp.625-629
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• 2011

To investigate the protective effect of eggplant (Solanum melongena L.) and its active compound, delphinidin, we used in vitro and cellular system. The active fraction from eggplant, BuOH fraction, showed protective effect from hydrogen peroxide-induced oxidative stress in WI-38 fibroblast cells. It suggests that eggplant would have the protective activity from radical-induced oxidative damage and its BuOH fraction would play the crucial role with antioxidative activity. In addition, delphinidin, the active compound from eggplant, exerted the strong 1,1-diphenyl-2-picrylhydrazyl scavenging effect with $IC_{50}$ value of 6.59 ${\mu}g/mL$. Furthermore, the cellular oxidative stress was induced by 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH) in LLC-$PK_1$ cells, while treatment of delphinidin atteunated AAPH-induced oxidative stress as dose-dependent manner. The present study suggests the antioxidative activity of eggplant and delphinidin against free radical-induced oxidative stress.

• Journal of Environmental Science International
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• v.33 no.6
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• pp.417-425
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• 2024

This study investigated the effects of various planting models on the joint cultivation of eggplant (Solanum melongena) and marigold (Tagetes erecta)to enhance sustainable rooftop urban farming. Rooftop agriculture is increasingly valued to boost the food supply and benefit the environment. Integrating such practices into urban planning is viewed as a way to sustainably manage resources and improve the food-energy-water cycle in cities. The experiment was conducted on a rooftop in Chungju, South Korea from May to August. Four different planting setups were used: central eggplant with peripheral marigold (SET), eggplant with a protective net (SIC), central marigold with peripheral eggplant (TES), and control with only eggplant (CON S). These models tested the effects of companion planting versus monoculture using a lightweight soil mix ideal for rooftops made from cocopeat and perlite and enriched with organic fertilizer. Measurements focused on soil conditions and plant health and assessed soil temperature, moisture, conductivity, plant height, width, and leaf size. The results indicated that the SET modelyielded the best growth. This setup benefited from marigold pest control properties and its ability to improve soil conditions by enhancing moisture and nutrient levels and aiding eggplant growth. These findings underscore the potential of mixed planting on rooftops and suggest that such approaches can be effectively incorporated into urban agriculture to boost yield and environmental sustainability. This study supports the idea that diverse planting methods can significantly affect plant growth and promote urban greening and food security.