• 치과방사선
• /
• 제29권2호
• /
• pp.549-559
• /
• 1999

Leiomyosarcoma is extremely rare in the oral cavity and especially in the mandible. At first. the case of this report was diagnosed as odontogenic fibroma but after approximately 3.5 years. it was diagnosed as leiomyosarcoma. Conventional radiograph of the first time showed an ill-defined radiolucent lesion in the mandible. After local recurrence. CT images showed a large irregular soft tissue mass with some necrotic areas. These findings were not specific for leiomyosarcoma, but they suggested that this lesion was a recurrent soft tissue sarcoma. Histopathological examinations using H & E staining, immunohistochemical staining and Masson's trichrome staining confirmed this case as leiomyosarcoma. Deciding its malignancy or benignancy, defining the tumor extent and its relationship to the surrounding anatomic structures, and evaluating the distant metastasis are more important roles of radiographic examination than finding out the name of disease.

• 대한세포병리학회지
• /
• 제11권1호
• /
• pp.59-63
• /
• 2000

Extraskeletal osteosarcoma is an uncommon tumor originated from soft tissue without evidence of skeletal involvement. It usually affects adults and its common locations are extremity, buttock, and retroperitoneum. Although the histologic feature of this tumor is well known, there have been few reports on the fine needle aspiration cytologic findings. We report the imprint cytologic feature of extraskeletal osteosarcoma. The patient was a 49-year-old man with a mass of the left anterior chest for 2 years. On the Imprint preparation, the smears showed malignant round, polygonal or spindle cells with coarsely clumped chromatin and occasionally prominent nucleoli. The malignant cells occur singly, in clusters, or associated with amorphous eosinophilic osteoid. Mitotic figures are also seen.

• Journal of Korean Neurosurgical Society
• /
• 제30권12호
• /
• pp.1422-1426
• /
• 2001

Neurenteric cysts are developmental cysts derived from embryonic endodermal layers. Fewer than 100 have been reported in which there were no associated bone or soft-tissue malformations and only six among those cases showed intramedullary location in the literatures. The authors report a 16-year-old young man with a thoracic intramedullary neurenteric cyst which presented with symptoms of axillary pain and paraparesis. The magnetic resonance imaging showed intramedullary mass extended from level of T3 to T7. There was no associated bone or soft-tissue anomaly. This cyst was partially excised and marupialized into subarachnoid space. The pathological findings were compatible with neurenteric cyst. Nine months later, the cyst recurred and at second operation, cyst wall was removed completely.

• Journal of Yeungnam Medical Science
• /
• 제24권2호
• /
• pp.315-321
• /
• 2007

혈관종성섬유조직구종은 드문 연조직 종양으로 소아와 청소년기에 주로 발생한다. 호발부위는 팔다리, 몸통, 머리와 목 등이다. 저자들은 등에 발생한 혈관종성섬유조직구종 1예를 경험하였기에 문헌 고찰과 함께 보고한다. 11세 남자가 등의 덩이를 주소로 내원하였다. 자기공명영상에서 등의 피하조직에 경계가 좋은 덩이가 관찰되었다. 덩이에 대한 절제가 시행되었다. 절제된 덩이는 $4.0{\times}3.6{\times}3.0cm$ 크기의 회백색을 띠었고, 장액과 혈액덩이로 차있는 낭성공간이 보였다. 조직학적으로 종괴는 섬유성 거짓피막으로 둘러 싸여 있었고 여기에 만성염증세포 침윤이 동반되어 있었다. 종양세포는 방추형 혹은 난원형이고 결절성 증식을 하고 있었고, 혈액으로 차여진 혈관성 공간이 관찰되었다.

• Journal of Korean Neurosurgical Society
• /
• 제29권3호
• /
• pp.430-433
• /
• 2000

Infantile myofibromatosis is a rare and benign myofibroblastic tumor that may occur in either solitary or multicentric form in the soft tissue of infants. A 13-month-old girl presented with a painless firm mass, measuring $2.5{\times}2.5cm$ in the right temporal area. Skull X-ray and CT scan revealed a well enhancing soft tissue tumor with a round skull defect and sclerotic margin. The tumor was totally excised with curettage of the skull defect followed by cranioplasty. Pathology was confirmed to be a solitary infantile myofibromatosis. We report this rare solitary infantile myofibromatosis of the temporal bone with review of the pertinent literature.

• Archives of Plastic Surgery
• /
• 제50권1호
• /
• pp.101-105
• /
• 2023

Benign cartilaginous tumors, known as chondrogenic tumors, show cartilage components in the microscopic diagnosis. We present two clinical cases with cartilaginous tumors of the toes showing distinctive clinical manifestations. Two juvenile patients visited our outpatient clinic due to tumors with toenail deformities. A 10-year-old girl presented with a palpable mass with a nail deformity on the left third toe. The initial pathology report was soft tissue chondroma until complete resection. Another 15-year-old male patient visited the dermatology department with a toenail deformity and underwent a punch biopsy. The pathology report was fibrosis with myxoid degeneration. Excisional biopsies were performed for both patients. In the operative field, we observed exophytic tumors connected to the distal phalangeal bones. The final pathology reports were subungual osteochondroma on both patients. The specimen exhibited mature bone trabeculae with a focal cartilaginous cap. Benign cartilaginous tumors have a slow, progressive course and do not show significant symptoms. However, tumors in subungual areas are accompanied by toenail deformities and they can cause pain. Their clinical characteristics lead to a delayed diagnosis. Surgeons can be confused between soft tissue and chondrogenic tumors. When they conduct physical examinations, these categories should be considered in the differential diagnosis.

• 대한세포병리학회지
• /
• 제9권2호
• /
• pp.187-191
• /
• 1998

Alveolar soft part sarcoma(ASPS) is a rare malignant neoplasm with a distinct clinicopathologic entity of which fine needle aspiration(FNA) cytologic findings have been described in only a few reports. Although patients usually present with an isolated soft-tissue mass in the extremity, metastasis can occur in about 13 % of total cases and the most frequent metastatic site is the lung. We have recently experienced a FNA cytologic case of ASPS in the lung. A 23-year-old female patient was admitted to this hospital due to 2-month-history of cough She had been good in health before the visit. Chest computed tomography revealed multiple, variable sized, bilateral pulmonary nodules. Physical examination and other staging work up revealed no other lesions except for pulmonary nodules. A percutaneous transthoracic FNA was performed from the pulmonary nodules. The smear was cellular and most cells were arranged singly. In addition, a few clusters lined by thin-walled vasculature with a pseudoalveolar pattern were present. Some of the tumor cells were large and polygonal lo oval with abundant granular or vacuolated cytoplasm. Most cells were naked nuclei showing finely granular chromatin pattern with prominent central nucleoli.

• Archives of Plastic Surgery
• /
• 제34권4호
• /
• pp.495-497
• /
• 2007

Purpose: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms, usually arising from somatic soft tissues or peripheral nerves. Primary MPNST of the scalp is extremely rare. The case is being reported for its rarity. Methods: A 53-year-old female was presented with a scalp mass on vertex area. The tumor was localized in scalp skin and did not invade underlying periosteum or skull and treated with complete surgical excision followed by adjuvant chemotherapy and radiotherapy. Results: Histologically, the tumor showed malignant spindle cells with focal S-100 positivity on immunohistochemistry and a diagnosis of MPNST was made. Conclusion: Authors experienced a rare case of primary scalp MPNST and report the case.

• 한국임상수의학회지
• /
• 제27권4호
• /
• pp.474-482
• /
• 2010

Hepatocellular carcinoma (HCC) is a primary hepatic neoplasms in dogs. Three types of HCC such as massive, nodular and diffuse form were reported. Massive HCC is most common and has relatively better prognosis than other forms because this type of HCC can be removed surgically and has low frequency of relapse or metastasis. Diagnostic image can provide useful information for shape and internal structure of the hepatic mass as well as the location and adhesion or invasiveness of the mass to establish surgical plan to remove the mass safely. In this study, we investigated diagnostic features of massive HCC in 5 dogs. Radiography showed soft tissue mass in cranial abdomen in 3 dogs. On ultrasonography, all dogs had a solitary hepatic mass with mixed echo pattern with anechoic cysts, which represented necrosis and hemorrhage. The radiographic and ultrasonographic findings of affected hepatic lobe were compared with the macroscopic findings through laparotomy. Computed tomography was performed to check metastasis and figure out the origin of the mass in two dogs. Ultrasonography is useful and relatively sensitive examination for diagnosis and planning for surgery in canine massive HCC.

• 대한골관절종양학회지
• /
• 제20권2호
• /
• pp.54-59
• /
• 2014

목적: 사지에 발생한 연부 조직 악성 근상피종의 진단, 치료 및 예후에 대하여 알아보고자 하였다. 대상 및 방법: 2008년 1월부터 2014년 10월까지 연부 조직 악성 근상피종으로 진단받고 본원에서 치료받은 6명의 환자를 대상으로 하였다. 2명의 환자는 타원에서 조직 검사 없이 무계획 절제술(unplanned excision)을 시행받은 이후 본원으로 전원되었으며, 나머지 4명의 환자는 모두 본원에서 조직 검사 및 광범위 절제술을 시행받았다. 결과: 평균 연령은 41세(33-54)였고, 남자가 3예, 여자가 3예였으며 평균 추시 기간은 28개월(9-45)이었다. 1명의 환자에서만 술 후 항암요법을 시행하였다. 연구 대상 환자 중 4명만이 악성 연부 조직 종양 의심하에 조직 검사 후 광범위 절제술을 시행하였다. 본원에서 광범위 절제술을 시행한 환자 4명은 모두 절제연에 종양 세포가 관찰되지 않았다. 무계획 절제술 이후 전원된 환자 2명 모두 본원에서 재절제술 시행받았으며, 이중 한명은 재절제술 병리 조직에서 잔존하는 종양 세포는 관찰되지 않았다. 6명의 환자 모두에게서 수술 후 평균 6개월(3-29)에 국소 재발 소견이 관찰되었고 4명의 환자에서는 수술 후 평균 7개월(3-14)에 원격 전이도 관찰되었다. 원격 전이가 발생한 4명의 환자는 모두 질병으로 인하여 사망하였고, 국소 재발만 발생한 2명의 환자중 1명은 환자는 재발하여 추시 관찰 중이며 나머지 1명의 환자는 재수술후 2년간 재발이나 전이 없이 경과 관찰 중이다. 결론: 연부 조직 악성 근상피종은 극히 드물게 발병하는 질환으로 재발과 전이를 잘 하는 공격적인 악성 연부 조직 종양으로 적절한 치료법으로는 광범위 절제술이 권장되며, 국소 재발을 줄이기 위해서는 악성 연부 조직 종양일 가능성을 염두에 두고 반드시 술 전 조직 검사를 하여 악성임을 확인하고 이후 계획된 광범위 절제술을 시행하는 것이 중요하다고 생각된다.