• Title/Summary/Keyword: Soft tissue attenuation

Search Result 36, Processing Time 0.026 seconds

Digital Spectrum 분석방법을 이용한 조직특성 변수에 관한 연구 (Ultrasonic Tissue Characterization by Digital Spectrum Analysis Technique)

  • 곽철은;민병구
    • 대한의용생체공학회:의공학회지
    • /
    • 제5권1호
    • /
    • pp.55-62
    • /
    • 1984
  • A digital spectrum analysis technique was used to estimate the tissue characteristic parameters (transmission velocity and attenuation coefficient) in the phantom study and the human liver's ultrasound scanning. The soft tissue equivalent phantom was made with the combination materials of agar, water, powdered graphite, and n-propyl alcohol. In the human study, twenty five normal subjects and three patients with liver diseases were studied using the ultrasonic reflection signals and the spectrum analysis method The following results were obtained; 1. The soft tissue-equivalent materical could be produced with various acoustic parameters by changing the composition amount of the powdered graphite and n-propyl alcohol. 2. Attenuation coefficients of normal human liver tissue were estimated to be 0. 36 dB/cm MHz$\pm$0.11. In patients with liver disese, tile attenuation coefficients were shown to be different from the above normal values.

  • PDF

3-D High Resolution Ultrasonic Transmission Tomography and Soft Tissue Differentiation

  • Kim Tae-Seong
    • 대한의용생체공학회:의공학회지
    • /
    • 제26권1호
    • /
    • pp.55-63
    • /
    • 2005
  • A novel imaging system for High-resolution Ultrasonic Transmission Tomography (HUTT) and soft tissue differentiation methodology for the HUTT system are presented. The critical innovation of the HUTT system includes the use of sub-millimeter transducer elements for both transmitter and receiver arrays and multi-band analysis of the first-arrival pulse. The first-arrival pulse is detected and extracted from the received signal (i.e., snippet) at each azimuthal and angular location of a mechanical tomographic scanner in transmission mode. Each extracted snippet is processed to yield a multi-spectral vector of attenuation values at multiple frequency bands. These vectors form a 3-D sinogram representing a multi-spectral augmentation of the conventional 2-D sinogram. A filtered backprojection algorithm is used to reconstruct a stack of multi-spectral images for each 2-D tomographic slice that allow tissue characterization. A novel methodology for soft tissue differentiation using spectral target detection is presented. The representative 2-D and 3-D HUTT images formed at various frequency bands demonstrate the high-resolution capability of the system. It is shown that spherical objects with diameter down to 0.3㎜ can be detected. In addition, the results of soft tissue differentiation and characterization demonstrate the feasibility of quantitative soft tissue analysis for possible detection of lesions or cancerous tissue.

초음파 영상용 플라스틱 기반의 팬텀제작 및 특성 분석 (Analysis of Properties and Phantom Design Based on Plastic Hardener and Softener for Ultrasonic Imaging)

  • 이균정;박동희;신태민;서종범
    • 대한의용생체공학회:의공학회지
    • /
    • 제29권4호
    • /
    • pp.302-306
    • /
    • 2008
  • Plastic hardener and softener based ultrasound phantoms were made in various constitutions and their acoustic properties were measured. Speed of sound is approximately $1.4\;mm/{\mu}sec$ in all the phantoms, which is about 7% less than that of in soft tissue. Attenuation coefficient is strongly dependent on the ratio between hardener and softener. In order to achieve the tissue level attenuation (0.5 dB/cm/MHz), 60% of hardener or less is required. The synthesized phantoms can be preserved for more than 6 months without structural degradation.

신소재를 사용한 인체조직모사물질의 합성과 초음파 물리적 특성에 관한 연구 (The Study on Ultrasound Physical Characteristic and Synthesis of Tissue Mimicking Materials Used New Materials)

  • 마상철;김화선;안영만
    • 대한방사선기술학회지:방사선기술과학
    • /
    • 제33권3호
    • /
    • pp.245-252
    • /
    • 2010
  • 본 연구는 주제인 폴리우레탄(polyurethane, PU)과 새로운 형태의 n-type 산란재를 사용하여 합성한 조직모사물질(tissue mimicking materials : TMM)에 대해 국제표준규격 IEC 60601-2-37(2007)의 Annex D.D가 권고한 인체 연조직(soft tissue)의 음향학적 특성 기준에 준해, 전파속도, 임피던스, 감쇠계수 특성 등을 분석하였으며, 영상특성은 SONOACE 9900C PRIME(MEDESON Co.), 3.5 MHz 컨벡스 프로브(2.5-5.0 MHz)로 초음파 휘도와 최대투과심도를 분석 평가하여 다음과 같은 결론을 얻었다. 주제인 prepolymer와 polyol mixture를 혼합하고 n-type 산란재를 0~8%로 점차 증가하여 합성하였을 때, 1. 조직모사물질의 전파속도는 산란재가 증가할수록 연조직에 더 가깝게 수렴(convergence)하였다. 2. 음향임피던스는 산란재가 감소할수록 연조직에 더 가깝게 수렴하였다. 3. 감쇠계수는 산란재가 증가할수록 증가하였다. 4. 영상 평균휘도는 산란재가 증가할수록 증가하였으나 역치가 있었다. 5. 최대투과심도는 산란재 6% 조직모사물질에서 연조직에 가깝게 수렴하였다.

PET-CT에서 감쇠보정 영상과 비감쇠보정 영상을 통한 Metal Artifact 보정에 대한 고찰 (Metal artifact SUV estimation by using attenuation correction image and non attenuation correction image in PET-CT)

  • 김준;김재일;이홍재;김진의
    • 핵의학기술
    • /
    • 제20권2호
    • /
    • pp.21-26
    • /
    • 2016
  • 최근엔 대부분의 PET-CT영상의 감쇠보정은 많은 강점을 가지고 있는 CT를 기반으로 사용하고 있다. 하지만 CT 검사때 metal artifact가 발생하게 된다면, PET 영상에서 영향을 주게 된다. 이에 본 논문에서는 감쇠보정 영상의 count와 비감쇠보정 영상의 count의 비를 통하여 보정계수($e^{-{\mu}x}$)을 구하였고 이를 통해 측정 SUV에 대입하여 실제 SUV를 추정하는 방법에 대하여 고찰해보았다. 실험장비로는 본원에서 사용하고 있는 Biograph mCT S(40)_SIMENS을 촬영 장비로 이용하였고, phantom은 micro phantom을 사용하였다. 팬텀 실험방법은 micro phantom에 metal artifact를 발생시켜 촬영한 뒤 감쇠보정 영상과 비 감쇠보정 영상으로 재구성하였다. 그리고 SIMENS 사의 Sygo.via VA11A 프로그램을 이용 감쇠보정 영상과 비 감쇠보정 영상의 count를 측정하고 이를 통해 보정계수를 구하여 Metal artifact 발생 부위와 Metal artifact 발생 직전 부위의 보정계수를 비교 분석해 보았다. 임상영상에서는 본원에 내원한 환자 10명($66{\pm}15$세)의 데이터를 이용하여 여러 장기의 평균 보정계수를 계산하였고, Metal artifact가 발생한 연부조직의 보정계수와 metal artifact가 발생하기 직전의 연부조직의 보정계수를 비교 분석하였다. 분석결과 phantom 실험에서는 밝은 artifact 부분에서의 보정 계수는 Metal artifact가 발생하지 않은 부분에서의 보정계수보다 평균 12%증가 되게 나타났다. 어두운 artifact 부분에서의 보정계수는 발생하지 않은 부분에서의 보정계수보다 6% 감소 되게 나타났다. 또한 phantom 실험결과 본 논문에서 사용한 식을 이용한 추정 SUV가 실제 SUV와 유의미한 차이가 없다는 것을 확인 할 수 있었다. 임상영상에서는 normal 장기의 보정계수를 계산 하였고, 이를 이용한 각 장기의 평균 보정계수를 계산하여 그래프를 작성하였다. 그리고 이 결과 값을 통해 CT number가 큰 조직 일수록 보정계수도 커지는 상호 비례 관계를 확인 할 수 있었다. 또한 metal artifact시 밝은 artifact 부분의 연부조직 보정계수는 metal artifact가 발생 하지 않은 연부조직 보정계수에 비해 평균 20% 증가, 그리고 어두운 artifact 부분은 10% 감소된 것으로 나타났다. 그래프로 작성한 soft tissue 평균값과 비교 하였을 때는 metal artifact가 발생 하지 않은 연부조직에 비해 밝은 artifact 부위는 평균 19% 증가 어두운 artifact 부위는 평균 9% 감소 된 것으로 나타났다. 즉 경우에 따라 각 개인의 보정계수를 계산 할 필요 없이 그래프로 작성한 평균값을 간편하게 활용 할 수 있을 것으로 사료된다. 이와 같이 실험결과로 보아 본 논문에서 제시하였던 감쇠보정 영상과 비 감쇠보정 영상에서의 count의 비를 통해 metal artifact가 발생하지 않는 부위의 보정계수와 발생한 부위의 보정계수를 구하고, 이를 활용하여 측정 SUV에 대입하여 실제 SUV를 추정하는 방법 역시 metal artifact 발생 부위의 더 정확한 정량분석 위하여 고려 해볼 수 있는 대안이 될 수 있을 것이라 사료 된다.

  • PDF

A Basic Study on the Variation of Temperature Characteristics for Attenuation Coefficient and Sound Velocity in Biological Tissues

  • Park, Heung-Ho
    • 대한의용생체공학회:의공학회지
    • /
    • 제14권3호
    • /
    • pp.273-282
    • /
    • 1993
  • This study is concerned with the temperature dependence characteristics of ultrasound parameters in biological tissues, which are basic on the noninvasive deep body temperature estimation. Used parameters are ultrasonic attenuation coefficient and sound velocity In order to accomplishment our purpose, several signal processing methods were used. Attenua4iorl coefficient was estimated by spectral difference method and sound velocity was estimated by P-P method. And we also examined these methods through a series of IN VITRO experi mentis that used tissue-mimicking phantom samples and biological tissue samples. In order to imitate the biological soft tissue two kinds of phantom samples are used, one is agar phantom sample which is composed of agar, graphite, N-propyl alcohol and distilled water, and the other is fat phantom sample which is composed of pure animal fat. And the ultrasound transmission mode and reflection mode experiments are performed on the pig's spleen, kidney and fat. As a result, it is found that the temperature characteristics are uniform in case of phan- tom samples but not in biological tissues because of complicate wave propagation within them. Consequently, the possibility of temperature measurement using ultrasound on biological tissue is confirmed and its results may contribute to the establishment of reference values of internal temperature measurement of biological tissues.

  • PDF

구멍갈파래(Ulva pertusa Kjellman)의 생태생리에 대한 생육기질의 효과 (The Effect of Substrate on Ecophysiological Characteristics of Green Macroalga Ulva pertusa Kjellman (Chlorophyta))

  • 최태섭;김광용
    • ALGAE
    • /
    • 제20권4호
    • /
    • pp.369-377
    • /
    • 2005
  • Seashore joining with land and sea, which is typical habitat for marine macroalgae, is classified two types of shore as soft- and hard-bottom shore according to topographical (geological) and ecological features. We compared two of Ulva pertusa Kjellman from two contrasting habitats, sandy (soft-bottom, Haenam) and rocky shore (hard-bottom, Hadong) in terms of chlorophyll-a fluorescence and its parameters, and various photosynthetic pigment and nutrient content in the tissue of those. Both of habitats were different in the light environment such as light attenuation coefficient and even in nutrient concentration of ambient seawater. Electron transport rate (ETR) of Ulva from sandy shore was higher than from rocky shore. The range of photosynthetic pigment content in the tissue of U. pertusa was significantly much more in from sandy shore, and also nitrogen and phosphorus content were significantly higher except for carbon content. However, there were no significant differences in the ratio of among photosynthetic pigments, and N:P ratio was similar between each other, even though significantly different. Our result implied on the reason of why most of green tides in the worldwide concentrated and frequently occurred at sites with sandy, muddy and silty bottoms, being classified as soft-bottom shore.

스펙클 패턴의 통계적 평균과 엔트로피 방식에 의한 초음파 감쇄계수 추정방법 (Attenuation Estimation of Soft Tissue by the Entropy Method and Statistical Averaging of Speckle Patterns)

  • 송태경;박종철;박송배
    • 대한의용생체공학회:의공학회지
    • /
    • 제10권3호
    • /
    • pp.253-260
    • /
    • 1989
  • 시간 영역에서의 초음파 강쇄계수 추정방법은 일반적으로 감쇄매절을 통과하면서 반사된 초음파 신호의 통계적인 특성의 해석을 기초로 한다. 따라서 선뢰할 수 있는 추정결과를 얻기 위해셔는 대게 충분히 많은 초음파 신호의 샘플을 펼요로 하게 된다. 감쇄계수를 추정하는 문제에 있어서, 이것은 감쇄계수 영상의 공간 해상도 체적내에서 통계적으로 다른 특성을 갖는 많은 스렉클 패턴이 필요하다는 것을 의마한다. 이 논문에서는 스펙클 패턴이 초음파 빔의 정확산함수에 따라 다른 통계적인 특성을 갖는다는 성질을 이용하여 초음파 선행변환자플 회전시키면서 각 회전각도에서 측방향 스캔을 함으로써 통계적 상관이 적은 다수의 샘플틀을 얻는 방법을 제안하였다. 이 방법은 최근에 우리가 제안한초음파 감쇄계수의 추정을 위한 엔트로피 방법과 결합되어 감쇄계수추정의 정확성을 증가시카고 공간해상도를 줄얼 수 있다. 인체의 연조직과 유사한 특성을 갖는 팬텀을 제작한 후 실험을 통하여 제안한 방법의 타당성을 검증하도록 하겠다.

  • PDF

6 MV 광자선조사면내 투과성필터에 의한 조직선량 (Scatter Dose in soft tissue using the partial attenuation filter for 6 MV X-ray of linear accelerator)

  • 최태진;김옥배
    • 한국의학물리학회지:의학물리
    • /
    • 제4권1호
    • /
    • pp.55-71
    • /
    • 1993
  • Measured and calculated the TMR and SMR factors from percent depth dose underpartial attenuators which cover the whole part of the radiation beam with variousfilter thickness from 0 to 50 mm. This study was performed for x-ray beams generated with a 6 MV linear acceleratorat source to surface distance of 100cm in a water phantom for Lipowitz metal. TMR(0,d,t) was derived from non-linear polynomial regression with field sizedifferencies and a given filter thickness. In this experiments, the TMR(0,10,50) of 50mm of filter thickness was showed13.6 % higher than that of open field and SMR(5,10,50) was 38.5% smaller than thatof open field in same depth.

  • PDF

Investigation of the suitability of new developed epoxy based-phantom for child's tissue equivalency in paediatric radiology

  • Yucel, Haluk;Safi, Aziz
    • Nuclear Engineering and Technology
    • /
    • 제53권12호
    • /
    • pp.4158-4165
    • /
    • 2021
  • In this study, tissue equivalency (TE) of a newly developed epoxy-based phantom to 3-5 years child's tissue was investigated in paediatric energy range. Epoxy-based TE-phantoms were produced at different glandular/adipose (G/A) ratios of 17/83%, 31/69%, 36/64% and 10/90%. A procedure was developed in which specific amounts of boron, calcium, magnesium, sulphur compounds are mixed with epoxy resin, together with other minor substitutes. In paediatric energy range of 40-60 kVp half-value layer (HVL) values were measured and then Hounsfield Units (HU) were determined from Computed Tomography(CT) scans taken in the X-ray energy range of 80-120kVp. It is found that radiation absorption properties of these phantoms in terms of the measured HVL values related to linear attenuation coefficients (µ) are very well mimicking a 3 years child's soft tissue in case a ratio of 10/90%G/A. Additionally, the HU values of phantoms were determined from the CT scans. The HU = 47.8 ± 4.8 value was found for the epoxy-based phantom produced at a ratio of 10/90%G/A. The obtained HVL and HU values also support the suitability of the new epoxy based-phantom produced at a ratio of 10/90%G/A for a satisfactory mimicking a 3 years child's soft tissue by 5%. Thus they can have a potential use to perform the quality controls of medical X-ray systems and dose optimization studies.