• 한국지반환경공학회 논문집
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• 제18권5호
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• pp.5-16
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• 2017

본 연구에서는 압밀을 고려한 고등 3차원 유한요소해석을 통하여 압밀이 진행중인 지반에 근입된 단독말뚝의 거동을 지배하는 주요인자에 대한 검토를 실시하였다. 일반적으로 실무에서 고려되는 최소 및 최대 범위의 성토고 및 연약지반의 탄성계수를 가정하여 단독말뚝을 고려하였다. 성토고가 높을수록 그리고 점토의 탄성계수가 작을수록 말뚝에 작용하는 부마찰은 증가하는 것으로 나타났으며, 부마찰력 및 침하는 성토고 보다는 점토의 탄성계수에 더 큰 영향을 받는 것으로 나타났다. 부마찰에 의한 말뚝의 부마찰력 및 침하는 압밀 초기 단계에서 비교적 빠르게 발생하는 것으로 분석되었다. 정마찰은 압밀 초기에는 발현되지 않았다가 압밀도 50% 이후부터 급격하게 증가하였다. 말뚝이 압밀이 상당히 진행된 압밀도 50% 이상인 지반에 설치되어도 비교적 큰 크기의 부마찰이 말뚝에 발생할 수 있는 것으로 분석되었다. 한편 부마찰이 발생 중인 말뚝에 하중을 작용시키면 그렇지 않은 경우에 비해 말뚝의 최종침하가 최대 약 95% 증가하는 것으로 나타났다. 부마찰이 작용하는 말뚝의 설계지지력은 부마찰이 작용하지 않는 말뚝에 비해 약 4-11% 감소하는 것으로 분석되었다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제23권3호
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• pp.263-269
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• 2001

하순 및 하악골 정중열은 매우 드문 선천성 기형으로 , 하순절흔에서부터 하악은 물론 경부, 흉부까지 연장되어 다양하게 나타날 수 있으며, 원인은 확실하지 않으나 정중부로의 중배엽의 침투 실패, 하악돌기의 유합부전 그리고 외부 요인들이 논의되고 있다. 치료방법 및 시기에 관해서는 임상소견이 다양하고 증례가 드물기 때문에 많은 논란이 있어왔다. 그러나 현재의 경향은 연조직 기형은 연하 및 발음의 기능적 장애를 예방하기 위하여 가능한 조기에 치료하며, 악골고정을 위한 강선 결찰 혹은 골이식술은 사춘기 후로 미루는 추세이다. 본 교실에서는 저작 장애를 주소로 내원한 8세 여자 환자의 임상소견에서 하악골 정중열과 하순의 수술로 인한 반흔조직 및 하순에서부터 치조골을 가로지르는 섬유성 소대 등을 발견할 수 있었으며, 하악의 정중열을 장골 이식을 이용 하여 양호한 결과를 얻을 수 있었으며, 추후 하순과 순. 설측 전정의 연조직 기형은 심미성과 기능 향상을 위해 부가적인 술식이 필요하리라 생각된다.

• Journal of Periodontal and Implant Science
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• 제25권3호
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• pp.539-556
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• 1995

Periodontal therapeutic modalities should be re-establishing and regenerating the periodontal tissue previously lost to the disease. To achieve periodontal regeneration, periodontal ligament cells must selective migrate to the deneded root surface, attached and proliferated it. Local pH concentration is one of the most factors that periodontal regeneration. The aims of this study were to examine on biological effects of pH to the human periodontal ligament cells in vitro, especially on the cell morphology, attachment, activity, vitality and viability. Human periodontal ligament cells were cultured from extracted tooth for non-periodontal reason. Immediately after extraction, any soft tissue adhering to the cervical parts of the roots was carefully removed with a sterile curette. To produce different pH levels in the media, Eagle's MEM was adjusted from pH 6.6 to 8.2 in 0.2 intervals with 1 M NaOH and 1 N HCl. After cultivation, Then, Periodontal ligament cells were cultured at pH ranging from 6.6-8.2. attachment assay was done at 1, 2 day incubation and activity assay was done at 1, 2, 3 day incubation. The experiments were evaluated by scaning electron microscopic techniques (HITACHIX-650 Scaning Electron Microanalyzer, Tokyo, Japan), MTT assay, and the cultured periodontal ligament cells were fixed in neutral formalin for 24 hours and immunohistochemically processed by PCNA for proliferating ability. The surviving cells in the medium showed slightly increased volume and widening intercellular distances at low concentration of pH than control group (pH 7.4), and apparently shrinkage at high concentration of pH than control group (pH 7.4). The results of the statistical analysis from the experiment on attachment, vitality and viability were as follows. Attachment of periodontal ligament cells at 1st and 2nd day, similar attachment rate of low concentration pH compared with control value (pH 7.4). But above pH 8.0, attachment rate were statistically significant decrease from control value(P<0.05). Periodontal ligament cell's activities were maximum at pH 7.6 by MTT assay. Similar with control value at low concentration of pH. But, the activities were statistically significant decrease at high concentraration of pH(P<0.05). Cellular proliferating rate (PCNA index) were statistically significant decrease from control value at low and high concentration of pH(p<0.05). This results suggested that hjgh concentration pH, in other words, alkali pH was cytotoxic effects on human periodontal ligament cells in vitro.

• Archives of Reconstructive Microsurgery
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• 제19권1호
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• pp.37-45
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• 2010

Purpose: First introduced by Buncke and Rose in 1979, the neurovascular partial $2^{nd}$ toe pulp free tissue transfer has been attempted to reconstruct posttraumatic finger tip injuries. Although some surgeons prefer other reconstructive methods such as skin graft and local flap, we chose the partial $2^{nd}$ toe pulp flap owing to its many advantages. We report three successful surgical cases in which the patients had undergone this particular method of reconstruction. Methods: We retrospectively examined three cases of fingertip injury patients due to mechanical injury. Bone exposure was seen in all three cases, All had undergone partial toe pulp free flap for soft tissue defect coverage. Results: All flaps survived without any complications such as partial necrosis, hematoma or dehiscence. Although tingling sensation has returned in both cases, two-point discrimination has not returned yet. Currently no patient is complaining of any pain which gradually improved during their course of recuperation. All stitches were removed on postoperative 2 weeks. Patients are satisfied with the final surgical result and there are no signs of any edema or hematoma. Conclusion: The homodigital reconstruction of finger tip injury using the partial $2^{nd}$ toe pulp flap has numerous advantages compared to other reconstructive modalities such as its resistance to wear and tear and in that it provides a non-slip palmar digital surface. However it requires microsurgery which may not be preferred by surgeons. Advanced age of the patient can be a relative contraindication to this approach since atheromatous plaque from the donor toe can compromise flap circulation after surgery. We report three successful cases which patient age was considered appropriate. Further investigation with a larger number of cases and long term follow-up is deemed necessary.

• 한국지반공학회논문집
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• 제34권9호
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• pp.33-42
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• 2018

야지궤도차량 구동 시 무한궤도를 통해 전달된 엔진출력은 지반-궤도 접지면에서 지반을 전단시켜 슬립변위 및 지반추력을 발현시킨다. 이때 지반추력의 반력이 야지궤도차량의 구동력으로 작용하는데, 지반이 연약하여 구동에 필요한 지반추력을 확보하기 어려운 경우에는 무한궤도 표면에 그라우저를 부착하여 구동성능을 개선시킨다. 본 연구는 그라우저 효과를 적절히 고려하여 야지궤도차량의 지반추력을 평가하기 위한 기초연구로서 수행되었다. 우선 지반-궤도 접지면의 전단메커니즘을 바탕으로 그라우저가 부착된 야지궤도차량의 지반추력을 평가하기 위한 방법을 새로이 제안하였다. 이를 통해 그라우저가 야지궤도차량의 구동성능에 미치는 영향을 평가한 결과, 그라우저가 부착됨에 따라 야지궤도차량의 전체지반추력이 증가하여 구동성능이 개선되는 것을 확인하였다. 특히, 그라우저의 길이가 증가하고 간격이 가까울수록 전체지반추력 증가효과가 명확해지는 것으로 나타나, 그라우저 형상비(=간격/길이)가 작을수록 야지궤도차량의 구동성능을 더욱 크게 개선시킬 수 있을 것이라 판단된다.

• Journal of Periodontal and Implant Science
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• 제27권2호
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• pp.317-328
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• 1997

Since laser therapy has been applied to dentistry, many dental practitioners are very interested in laser therapy on various intraoral soft tissue lesions including gingival hyperplasia and aphthous ulcer. The purpose of the present study was to determine the therapeutic effect and the harmful effect of a pulsed-Nd:YAG laser irradiation on human gingival tissue. In twenty periodontal patients with gingival enlargement, the facial gingival surface of maxillary anterior teeth was randomly irradiated at various power of 1.0W(100mJ, 10Hz), 3.0W(100mJ, 30Hz) and 6.0W(l50mJ, 40Hz) for 60 seconds by contact delivery of a pulsed-Nd:YAG laser(EN.EL.EN060, Italy). Immediately after laser irradiation, the gingival tissues were surgically excised and prepared in size of 1mm3. Subsequently the specimens were processed for prefixation and postfixation, embedded with epon mixture, sectioned in $1{\mu}$ thickness, stained with uranyl acetate and lead citrate, and observed under transmission electron microscope(JEM 100 CXII). Following findings were observed; l. In the gingival specimens irradiated with l.OW power, widening of intercelluar space and minute vesicle formation along the widened intercellular space were noted at the epithelial cells adjacent to irradiated area. 2. In the gingival specimens irradiated with 3.0W power, the disruption of cellular membrane, aggregation of cytoplasm, and loss of intercellular space were observed at the epithelial cells adjacent to irradiated area. 3. In the gingival specimens irradiated with 6.0W power, the disruption of nuclear and cellular membrane was observed at the epithelial cells adjacent to irradiated area. The ultrastructural findings of this study suggest that surgical application of a pulsed-Nd:YAG laser on human gingival tissue may lead somewhat delayed wound healing due to damage of epithelial cells adjacent to irradiated area.

• Journal of Periodontal and Implant Science
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• 제26권1호
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• pp.27-46
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• 1996

The purpose of this study was designed to compare with the effects of 4 different surface active bioceramics on the healing process of alveolar bone defects in dogs. Artificial alveolar bone defects depth 4-6mm, width 3-4mm) were created with # 6 round bur at interproximal areas of maxillary canine, maxillary 2nd premolar, mandibular canine, and mandibular 3rd premolar. porous hydroxyapatite(Interpore $200^R$) , 45S5 bioglass, CJ4/lOC crystalline glass, and JJ crystalline glass were implanted in intrabony defects randomly. Experimental groups were divided into 4 categories according to its implant material. After implantation, all groups were examined postoperatively 4 weeks to 12 weeks. 3 dogs was selected randomly and sacrificed after vascular perfusion with 2.5% glutaraldehyde at every 4 weeks. Tissue blocks with surroundig alveolar bone and soft tissues were removed and immersed in formaldehyde/glutaraldehyde fixative. After 20 weeks decalcification with EDTA and formic acid, sections were made and observed under light microscope and transmission electron microscope. In all experimental groups, the encapsulation of inactive connective tissue was observed around graft particles in 4 weeks. As time elapsed, the thickness of surrounding connective tissue was decreased. Osteoconductive bone growth pattern was seen apparently in all groups. CJ4/lOC crystalline glass showed the most active bone formation until 8 weeks. 45S5 bioglass was, however, the most active in new bone formation at 12 weeks. Though there was difference in resorption rate among grafting materials, the size of graft particles was decreased gradually. 45S5 bioglass was resorbed faster than the others. On the other hand, porous hydroxyapatite was degraded most slowly. Phagocytosed particulate matters was observed in the cytoplasm of multinuclear multinuclear giant cell and macrophage under transmission electron microscope. The results suggested suggested that 45S5 bioglass and CJ4/lOC crystalline glass may have some enhanced reparative potential when compared to porous hydroxapatite in the treatment of periodontal defeds. JJ crystalline glass reguires a further investigation of the safety of its use.

• 대한소아치과학회지
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• 제29권4호
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• pp.581-585
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• 2002

Focal epithelial hyperplasia(FEH)는 구강편평상피의 국소적인 증식으로 사람유두종바이러스(Human papilloma virus)에 의해 유발되는 것으로 알려져 있다. 보통 어린 나이에 호발하며 종종 젊은 성인에서 발생하기도 한다. 협,순측 및 설측 점막에 호발하지만 치은이나 혀의 병소(lesions of tongue)도 보고된 바 있다. 이 병소는 전형적으로 다발성인 부드럽고 촉진 시 압통이 없는 편평한 구진이나 반의 형태를 갖는다. 종종 유두상의 표면을 보이기도 한다. 각각의 병소는 비교적 작고 분리되어 있으며 잘 경계지어진다. FEH의 조직학적 특징은 구강 상피의 유극세포증(acanthosis)이다. 그 밖에 바이러스에 의한 세포병리학적 변화를 나타내는 구멍세포(koilocyte)나 유사분열상 세포(mitosoid cell)가 관찰되기도 한다. 본 증례의 5세 여자환아는 치은의 돌기성 병소를 주소로 연세대학교 치과대학병원 소아치과에 내원하였다. 임상구강검사 결과 무경형의 유두상 구진(sessile papillary papules)이 상악 좌우측 제 2 유구치 협측 치은에서 관찰되었다. 촉진 시 동통은 없었다. 조직학적 검사를 위해 조직생검을 시행하였으며, 유극세포증이 관찰되었다. 이에 FEH로 진단되어 보고하는 바이다. FEH는 몇 달이나 몇 년 이내에 자발적으로 소멸하므로 일반적으로 치료는 불필요하다. 다만 진단적인 이유나 심미적인 이유로 보존적인 절제술을 시행하기도 한다. 이러한 치료 후 재발의 위험은 최소한이며, 악성 전이 가능성 역시 거의 없다.

• 한국산림과학회지
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• 제88권2호
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• pp.240-248
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• 1999

본(本) 연구(硏究)는 집중호우로 인하여 임도재해가 발생된 강원도(江原道) 춘천지역(春川地域)의 5개 임도(林道)를 대상으로 임도구조요인 4항목과 입지요인 4항목을 이용하여 수량화(數量化)II류(類)에 의한 임도성토사면(林道盛土斜面)의 붕괴요인(崩壞要因) 평가(評價) 및 예측(豫測)을 실시하였다. 그 결과는 다음과 같다. 임도구조요인(林道構造要因)인 종단(縱斷)물매는 $2^{\circ}$ 이하 및 $4^{\circ}$ 이상, 유하거리(流下距離)는 80m 이상, 성토사면(盛土斜面)길이는 6m 이상, 성토사면경사(盛土斜面傾斜)는 $35^{\circ}$ 이상에서 성토사면의 붕괴위험도가 높은 것으로 나타났으며, 임도입지요인(林道立地要因)인 임도노선위치(林道路線位置)는 능선부, 사면구성물질(斜面構成物質)은 풍화암과 연암, 산지경사(山地傾斜)는 $35{\sim}45^{\circ}$, 사면종단면형(斜面縱斷面形)은 철(凸)형과 요(凹)형 사면에서 붕괴위험도가 높은 것으로 나타났다. 또한 사면붕괴에 영향을 미치는 인자는 성토사면길이, 사면구성물질, 임도노선위치 등의 순으로 나타났으며, 판별적중율(判別的中率)은 86.5%로서 높은 적중률을 나타냈다.

• 대한치과보철학회지
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• 제31권2호
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• pp.249-270
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• 1993

For understanding of anatomy, physiology, and diseases of human TMJ, it is required to evaluate quantitatively the movement of the disc and condyle head of mandible. The histologic section of cadaver TMJ were examined, and the magnification of the MR image and its details of anatomy were evaluated. And then a quantitative analytic method, by comparing the Sectograph and the MR image of vital human TMJ, was proposed. For this study, 15 subjects(Male, 24~35years) were selected from a prosthodontic examination randomly, and each subject’s five interocclusal rubber registration records were made on the ICP, and 5, 10, 15, and 20mmjaw opening positions. All subjects were radiographed with a Denar Quint Sectograph Image System(Denar Corp., USA), and imaged with a MRP-20EX MR Image System(0.2T, Permanent Magnet Type, Hitachi Medical Corp., Japan) using an 100mm diameter bilateral type surface coil. These images were traced on the acetate tracing paper, and analyzed In this study, the findings led to the following conclusions. 1. In comparison of the histologic section of autopsy specimen with the MR image at the same section, the size(dimension) of MR image was 70% of the real one. It was possible to recognize the shape of articular disc, anterior and posterior attachments, and adjacent soft tissues, because of the excellent reproducibility of anatomical structure. 2. When we compared the amount of joint space on MR image with that of joint space on sectograph, the amount of joint space on sectograph was significantly greater than that of joint space on MR image, except at the top of condylar head. 3. The position of minimum joint space on sectograph at intercuspal position didn't coincide with the middle position of articular disc on MR image, and was approximately in the anterior third of posterior band of articular disc. 4. The amount of condylar movement on MR image at opening movement was greater than that of articular disc movement. From Intercuspal position to 5mm jaw-opening movement, the condylar movement showed hinge one, and over the range 5mm jaw-opening it suggested hinge & translatory one. 5. In terms of area variation of articular disc measured on MR image in sagittal plane, the area of posterior band increased with increasing the amount of Jaw opening, but the area of anterior band decreased conversely.