• 제목/요약/키워드: Soft Surface

검색결과 971건 처리시간 0.03초

Polymer brush: a promising grafting approach to scaffolds for tissue engineering

  • Kim, Woonjung;Jung, Jongjin
    • BMB Reports
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    • 제49권12호
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    • pp.655-661
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    • 2016
  • Polymer brush is a soft material unit tethered covalently on the surface of scaffolds. It can induce functional and structural modification of a substrate's properties. Such surface coating approach has attracted special attentions in the fields of stem cell biology, tissue engineering, and regenerative medicine due to facile fabrication, usability of various polymers, extracellular matrix (ECM)-like structural features, and in vivo stability. Here, we summarized polymer brush-based grafting approaches comparing self-assembled monolayer (SAM)-based coating method, in addition to physico-chemical characterization techniques for surfaces such as wettability, stiffness/elasticity, roughness, and chemical composition that can affect cell adhesion, differentiation, and proliferation. We also reviewed recent advancements in cell biological applications of polymer brushes by focusing on stem cell differentiation and 3D supports/implants for tissue formation. Understanding cell behaviors on polymer brushes in the scale of nanometer length can contribute to systematic understandings of cellular responses at the interface of polymers and scaffolds and their simultaneous effects on cell behaviors for promising platform designs.

구형 인덴테이션 평가에 의한 비대칭적 층상형 세라믹 부품의 설계연구 (The Optimum Design Study of Asymmetric Layered Ceramic Component by Spherical Indentation)

  • 이기성;김태우;김철
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 추계학술대회
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    • pp.297-301
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    • 2004
  • The optimum design against contact crack initiation is investigated to find major parameters in designing desirable surface-coated asymmetric layered components. Hard ceramic coated soft materials with various elastic modulus mismatch are prepared for the analysis. Spherical indentation is conducted for producing contact cracks from the surface or interface between the coating and the substrate layer. A finite element analysis of the stress fields in the loaded layer components enables a direct correlation between the damage patterns and the stress distributions. Implications concerning the design of asymmetric layered components indicate that the coating thickness and the elastic modulus mismatch are important parameters for designing layered component to prevent the initiation of contact cracks.

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휴대전화기 신제품 개발을 위한 컨조인트분석 (Conjoint Analysis for the Development of New Cellular Phone)

  • 김부용
    • 품질경영학회지
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    • 제33권4호
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    • pp.103-110
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    • 2005
  • Advanced function has been considered to be the most important aspect of the cellular phone. However, leading companies are now implementing the fashion branding strategy which stresses both high technology and appealing design. By means of the conjoint analysis, this research focuses on identifying the preferred design profile related to style of the key cover, color and texture of the case, and presence or absence of the noctilucent material coated on the part of surface. We also evaluate the relative importance of factors to determine the design concept of new cellular phone. Results indicate that consumers most prefer the silver-colored, sliding key cover phone with soft and noctilucent surface.

늑간신경에 발생한 신경초종 1예 (A Case of Neurilemmoma of Intercostal Nerve)

  • 이두연;계기식;송계용
    • Journal of Chest Surgery
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    • 제11권3호
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    • pp.239-245
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    • 1978
  • Recently, we experienced a case of rare neurilemmoma originated from intercostal nerve [9th] in the right chest wall in a 25 year old male officer. The tumor was incidentally found in the routine chest X ray, where the round well circumscribed mass tumor the ninth rib with notching and sclerotic margin, suggesting slowly growing benign benign of chest wall was revealed and the tumor mass was easily extirpated in the exploratory thoracotomy, with uneventful recovery. Grossly, the tumor was firm, partly soft and well circumscribed, measuring 4.5X3.0X 3.0 cm with yellowish smooth outer surface, attached with intercostal nerve trunk. Cut surface exhibits partly grayish white and largely hemorrhagic areas. Microscopically, the characteristic palisading arrangement of schwann cells and Verocay bodies are seen but dominant features are cystic degeneration and hemorrhage with organization and fibrosis. The sheath of intercostal nerve and capsule of neurilemmoma were con joined. There is no evidence of malignancy. The tumor was confirmed as neurilemmoma of intercostal nerve, Antony type B.

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유효강성을 줄인 새로운 형상의 건식부착물 제작 (Fabrication of a novel dry adhesive structure with reduced effective stiffness)

  • 조영삼;정대환;한혁섭;김완두
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2007년도 춘계학술대회A
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    • pp.421-425
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    • 2007
  • In the fabrication of dry adhesive structure, increasing contact-points or contact-area is the primary goal because the adhesive force grows in proportion to the contact-area. The simplest way to extend the contact surface is the fabrication by using soft materials. However, the column-array structure could confront the matting phenomenon which columns are stuck together. Therefore, we need a novel design to reduce the effective stiffness with adequate stiff materials like a gecko's setae. In this study, we propose a novel design for the dry adhesive structure. Moreover, we analyzed whether the adhesive structure conforms the rough surface sufficiently through finite element method adopted the non-bonding interaction as the body force. Also, we fabricated the novel structures via UV lithography and some techniques. In addition, we examined the adhesive force of the novel structures.

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X-ray Computed Tomography를 이용한 콘크리트의 손상파라미터 정량화 (Introduction to Qunatification of Damage Parameters for Concrete Using X-ray Computed Tomography)

  • 박대효;박재민;안태송
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2003년도 가을 학술발표회 논문집
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    • pp.501-504
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    • 2003
  • The purpose of this work is to introduce some fundamental stereological concepts to quantify damage parameters using X-ray CT(Computed Tomography) in the scope of CDM(Continuum Damage Mechanics). X-ray CT is a completely nondestructive technique for visualizing features in the interior of opaque solid objects, and for obtaining digital information on their 3D geometries and properties. Many researchers have introduced lots of damage parameters to model the mechanical behavior of deteriorated materials. Those damage parameters can be represented in many forms such as specific void or crack surfaces, the spacing between cracks, the specific damaged surface area, the specific damaged surface area tensor, the mean solid path among the damaged surfaces and the mean solid path tensor. Despite of many accomplishments in CDM since there is no the systematic experiment, it have limitations in application. In this situation, X-ray computed tomography is highlited by many researchers and applied in a wide range of materials including rock, bone, ceramic, metal, soft tissue and concrete.

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서해안 지역 실트샌드의 매립직후 공학적 특성에 관한 연구 (Study on Engineering Properties after Reclamation in Silty Sand Soil Layers of Western Ocean)

  • 양태선;심민보;양태규;김주현
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2006년도 춘계 학술발표회 논문집
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    • pp.1054-1059
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    • 2006
  • For reclamaing fill materials, hydraulic fill is needed in domestic parts of the reclamation sites every year. Engineering properties of soils after reclamation is calculated by laboratory. But before or after reclamation, reclamation quatities depend on the depth from the ground surface when hydraulic fill is dumped. In this paper, the engineering properties on the depth from ground surface are assumed by cone penetration test where fine grained soft soil is formed is proposed through several sites.

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Optimal Guidance and Nonlinear Tracking Control for a Lunar Lander

  • Hwang, Myung-Shin;Kim, Jin-Ho
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2001년도 ICCAS
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    • pp.167.2-167
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    • 2001
  • This paper presents guidance and control laws which guarantee a minimum fuel consumption and have obustness against various disturbances during a terminal-landing phase on the lunar surface. The nonlinear robust tracking control system is designed to track the reference profiles, which are expressed by exponential functions. An adjustment law in the tracking controller is given in the form of the differential equations with respect to the controller´s variable gains. Computer simulations are performed to examine the tracking accuracy, the robustness in a thrust failure mode, and the vertical soft landing at a pre-assigned point on the lunar surface. The results of numerical simulation show the effectiveness of the present control law.

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플라즈마 질화처리한 중, 고탄소저합금강의 내식성에 관한 연구 (Characteristics on Corrosion Resistance of Medium High Carbon Low Alloy Steels using Plasma Nitriding Process)

  • 이병찬
    • Journal of Advanced Marine Engineering and Technology
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    • 제22권5호
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    • pp.702-711
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    • 1998
  • The characteristics of corrosion resistance for the surface of medium high carbon steels and low alloy steels utilizing as manufacturing the machinery structures and machining tools and treating by plasma/ion nitriding process have been studied in terms of electrochemical polarization behav-iors including corrosion potential(Ecorr) anodic polarization trends and polarization resistance(Rp) The seven base materials showed a clear passivation behavior for the polarization tests in the ASTM standard solution 1N ${H_2){SO_4}$ Although the treated surface by plasma nitriding for the seven test materials showed a significant increase in hardness the treatment gave a detri-mental effect in corrosion resistance. The various characteristics including corrosion potential polarization curves microstructures corrosion current polarization resistance among non-treat-ed nitriding and/or soft-nitriding treated specimens have been investigated and some of the mechanisms discussed.

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Fe-Hf-N 연자성 박막의 자기적 특성에 미치는 박막 두께의 영향 (The Effect of Thicknesses on Magnetic Properties of Fe-Hf-N Soft Magnetic Thin Films)

  • 최종운;강계명
    • 한국표면공학회지
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    • 제44권6호
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    • pp.255-259
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    • 2011
  • The thickness dependence of magnetic properties was experimentally investigated in nanocrystalline Fe-Hf-N thin films fabricated by a RF magnetron sputtering method. In order to investigate the thickness effect on their magnetic properties, the films are prepared with different thickness ranges from 90 nm to 330 nm. It was revealed that the coercivity of the thin film increased with film thickness. On the contrary, the saturation magnetization decreased with film thickness. On the basis of the SEM and TEM, an amorphous phase forms during initial growth stage and it changes to crystalline structure after heat treatment at $550^{\circ}C$. Nanocrystalline Fe-Hf-N particles are also generated.