• Title/Summary/Keyword: Sodium phosphate

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Studies on Dosage Form Design of Anticancer Drug: Release of 5-Fluorouracil from Silicone Devices Containing Water Soluble Additives (항암제(然癌劑) 제형(劑形) 개발(開發)에 관(關)한 연구(硏究) : Silicone Rubber-수용성(水溶性) 첨가제(添加劑)의 Device에서 5-Fluorouracil의 용출(溶出))

  • Kim, Sung-Ho;Choi, Jun-Shik;Back, Chae-Sun;Yu, Young-Jong;Lee, Chi-Young
    • Journal of Pharmaceutical Investigation
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    • v.16 no.1
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    • pp.1-7
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    • 1986
  • The influences of sodium chloride, polyethylene glycol 4000 and 20000 on 5-fluorouracil release from disk type silicone polymer devices were examined in isotonic phosphate buffer. These water soluble cosolvent and sodium chloride caused devices to swell in aqueous media. Sodium chloride exerted the greatest influence on drug release. The addition of water soluble cosolvent or sodium chloride to silicone polymeric devices permitted controlled release of 5-fluorouracil, presumably due to the change of the physical microstructure of silicone network, and the solubility and diffusivity of 5-fluorouracil. It seemed that the water soluble drug was released through the hydrophilic pores or pathways formed in the device by the incorporation of a water soluble cosolvent or sodium chloride.

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Evaluation of Cooling Water Corrosion Inhibitors by the Electrical Resistance Method (전기저항법에 의한 공업용수 부식억제제의 성능시험)

  • W. K. Min
    • Journal of the Korean Chemical Society
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    • v.7 no.4
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    • pp.251-253
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    • 1963
  • Six corrosion inhibitors for cooling water use were evaluated by means of a corrosometer in a laboratory bench scale test. A steel probe (Alloy 1020) was exposed and checked for the extent of corrosion in a recirculating water system, changing inhibitors and their concentrations at $40^{\circ}C$. A 95% inhibition was provided at the following concentrations of inhibitors. 50 ppm sodium hexametaphosphate 50 ppm commercial inhibitor A 50 ppm commercial inhibitor B 100 ppm disodium phosphate 200 ppm sodium chromate Sodium silicate was found to be use-less in this test. It was also observed that some inhibitors worked less effectively on the acid-cleaned steel probe.

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The Study on Sound Absorption According to Content of Foaming Agent In Lightweight Concrete (경량화 콘크리트에서 기포제의 함량에 따른 흡음특성에 관한 연구)

  • Hong, D.K.;Ahn, C.W.;Kang, J.G.;Woo, B.C.;Choi, J.G.;Kang, H.C.
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2006.05a
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    • pp.955-958
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    • 2006
  • The purpose of this study is to find ways of recycling a great amount of gypsum as by-product from the manufacture of phosphate fertilizer. For the purpose, this researcher investigated physical properties of light weight Porous material using waste gypsum and a foaming agent, Sodium n-dodecyl Sulfate to utilize it as a interior material of construction. To determine such properties, the study examined pore size distribution and pore rate in accordance with contents of Sodium n-dodecyl Sulfate added. Then expanded vermiculite as light-weight aggregate was also added, when pore size distribution, pore rate and sound absorption rate were surveyed and measured.

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Enamel strengthening effect of the dental fluoride compound (수종의 치과용 불소화합물의 물리적 조건에 따른 치질강화에 미치는 영향)

  • Kim, Joo-Won;Lee, Jung-Ae;Lee, Ka-Yean
    • Journal of Korean society of Dental Hygiene
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    • v.10 no.4
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    • pp.757-764
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    • 2010
  • Objectives : The fluoride coating for caries prevention and strengthen enamel use NaF(sodium fluoride, Junsei Chemical Co., Ltd, Japan) 2% gel, SnF2(stannous fluoride, SIGMA-ALDRICH Gmbh, USA)8% gel and APF(acidulated phosphate fluoride, Sultan health care, USA) 1.23% gel. Methods : After put the enamel piece in these fluoride compound gel, we observed density level. And after measuring the vickers hardness, Got the following conclusions. Results : 1. After settling in the APF 1.23% during 6 days, we observed high density level of enamel surface using 250 magnification scanning microscope. The vacuum of surface packed (in) like sardines. 2. After settling in the APF 1.23% during 6 days, we observed reducing the space between the cluster of enamel surface using 50,000 magnification scanning microscope. 3. The vickers hardness change was very much on the all kinds of fluoride compound gel[2% NaF(sodium fluoride)gel, 8% SnF2(stannous fluoride) gel, 1.23% APF(acidulated phosphate fluoride)gel]. It's all because of reducing the space between the cluster of enamel surface(p<0.001). Conclusions : The vickers hardness change was very much on the all kinds of fluoride compound. It's all because of reducing the space between the cluster of enamel surface.

Effects of Na3PO4 Concentration on the Porosity of Plasma Electrolytic Oxidation Coatings Surface on the 6061 Al Alloy, and Subsequent-NaAlO2 Sealing (6061 알루미늄 합금의 플라즈마 전해산화 피막의 표면기공율 및 부식특성에 미치는 Na3PO4 농도 및 NaAlO2 봉공처리의 영향)

  • Song, Euiseok;Kim, Yong-Tae;Choi, Jinsub
    • Journal of the Korean institute of surface engineering
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    • v.52 no.3
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    • pp.117-122
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    • 2019
  • In this study, surface porosity and corrosion resistance of PEO coatings prepared on the 6061 Al alloy were investigated in terms of sodium phosphate ($Na_3PO_4$) concentrations in an alkaline solution and $NaAlO_2$ sealing. The surface morphologies of the PEO coatings clearly show that the coatings film formed in $9g\;L^{-1}$ had the lowest porosity. The $NaAlO_2$ sealing was found to remove micropores and cracks existing on the surface of PEO coatings. As a result, the $NaAlO_2$ sealing resulted in the movement of corrosion potential toward more positive value and lower corrosion current density.

Effect of sodium hexa-meta phosphate as pore-sealing agent on the corrosion performance of Al-Zn coating deposited by twin-wire arc thermal spray process in 3.5 wt.% NaCl solution (3.5 중량% NaCl 용액에서 쌍선 아크 용사 공정으로 증착된 Al-Zn 코팅의 부식 성능에 대한 기공 밀봉제로서의 헥사메타인산나트륨의 영향)

  • Singh, Jitendra Kumar;Adnin, Raihana Jannat;Lee, Han-Seung
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2022.11a
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    • pp.81-82
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    • 2022
  • Al and Zn are used to protect the steel structures from corrosion. In the present studies, 15Al-85Zn alloy wires has been used for the deposition of coating by arc thermal spray process. Moreover, this process of coating exhibited severe defects formation, therefore, this coating was post-treated with different concentrations i.e. 0.05, 0.1 and 0.5M sodium hexa meta phosphate (Na6[(PO3)6]: SHMP) to fill to defects of deposited coatings and assessed their corrosion resistance in 3.5 wt.% NaCl solution with exposure periods. After the treatment, the porosity of the coating reduced significantly by formation of composite oxide films onto the coating surface. Initially, 0.5 M SHMP treated coating exhibited highest in total impedance due to significant reduction of porosity but once the exposure periods are extended, the composite oxides are dissolved, thus, total impedance is decreased.

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Immunogenic characterization of AlPO4 adsorbed Td vaccine and liposome-mediated Td vaccine

  • Remees Shuhsadhe;Junise Vazhayil;Heyam Saad Ali;Hiba Orsud;Ahmed Elmontaser Omer Mergani
    • Clinical and Experimental Vaccine Research
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    • v.12 no.3
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    • pp.232-239
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    • 2023
  • Purpose: The purpose of this study was to compare the antigenic potency and stability of tetanus and diphtheria (Td) vaccines when combined with aluminum phosphate (AlPO4) and liposome adjuvants. Materials and Methods: In vitro and in vivo analyses were conducted using the single radial immunodiffusion method and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The Td vaccines were prepared with AlPO4 adsorption and liposome-mediated delivery, and protein antigens were characterized using these methods. Results: The results revealed that the liposome-mediated Td vaccines exhibited higher immunogenicity compared to the AlPO4-adsorbed Td vaccines. Additionally, the liposome-mediated Td vaccines demonstrated higher stability as native antigens. Conclusion: This study highlights the importance of utilizing liposome adjuvants in vaccine development. The liposome-mediated Td vaccines showed enhanced immunogenicity and stability, making them a promising approach for improving vaccine efficacy. Understanding and optimizing adjuvant strategies can contribute to the development of effective vaccines against various diseases.

STUDY ON THE PROPERTIES OF GYPSUM-BONDED DENTAL INVESTMENTS (치과용 석고계 매몰재의 특성에 관한 연구)

  • Kim, Kyoung-Sun;Woo, Yi-Hyung;Choi, Boo-Byung
    • The Journal of Korean Academy of Prosthodontics
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    • v.28 no.1
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    • pp.137-163
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    • 1990
  • The properties of a investment material can be described by the consistency at the slurry state, the setting time, the compressive strength and the thermal expansion during the casting. In this study the effect of the production parameters which are included the ratio of quartz and cristobalite, the content of binder, the water powder ratio and the content and concentration of additives on the Properties of the gypsum-bonded investments has been investigated with help of the consistency test, the vicat needle test, the compressive strength test, the thermal expansion test, x-ray diffraction and DTA thermal differential test. The experimental results showed that the constitution of a investment with W/P ratio of 0.34, 30% of gypsum, 0.8% aluminium sulfate, 2% magnesium sulfate, 0.6% sodium phosphate was adapted for the properties of the KDA Spec. No. 13 type I investment. The important experimental results are summarized as follows. 1. The consistency of the investment decreased with increasing amount of aluminium sulfate and decreasing amount of sodium phosphate. An addition of magnesium sulfate up to 2% an increase of the consistency was shown. But 3% magnesium sulfate in investment showed a decrease of the consistency. The consistency did not vary significantly with a variation of the content of gypsum and cristobalite and the W/P ratio. 2. Aluminium sulfate and the magnesium sulfate promoted the hardening and the aluminium phosphate delayed the hardening. The setting time increased with amount of gypsum. The effect of the matrix on the setting time was insignificant. With the W/P ratio of 0.34 the setting time was 14 min. 3. The compressive strength decreased with the amount of aluminium sulfate up to 0.25% and increased with the amount of aluminium sulfate greater than 3%. The compressive strength decreased as decreasing the amount of magnesium sulfate and gypsum and as increasing the W/P ratio. The effect of the refractory on the compressive strength was also not significant. With the W/P ratio of 0.34 the compressive strength was $34Kg/mm^2$. 4. The 1st thermal expansion was found at the temperature near and the steady state or the contraction stage was found at the temperature between $250^{\circ}C$ and $500^{\circ}C$. After this stage the 2nd thermal expansion took place at the temperature near $500^{\circ}C$. The amount of thermal expansion increased with decreasing the content of magnesium sulfate, aluminium sulfate and gypsum and the W/P ratio. And the amount of thermal expansion increased as the content of sodium phosphate and cristobalite. With the W/P ratio of 0.34 the amount of total expansion was 1.2%.

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Long-term Variations of Chemical Properties in Controlled Horticultural Soils of Gyeongnam Province

  • Lee, Young-Han;Lee, Seong-Tae;Hong, Kang-Pyo;Lee, Sang-Dae;Kim, Je-Hong;Ok, Yong-Sik;Kim, Min-Keun;Kim, HyeRan
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.5
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    • pp.308-312
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    • 2013
  • The monitoring of chemical dynamic changes in controlled horticultural lands is very important for agricultural sustainability. Field monitoring was performed to evaluate the soil chemical properties of 200 controlled horticultural soil samples in Gyeongnam province every 4 years from 2000 to 2012. Soil chemical properties such as pH, amount of organic matter, available phosphate, nitrate nitrogen, and exchangeable potassium, calcium, magnesium, and sodium were analyzed. The amount of exchangeable calcium and soil pH were significantly higher in 2012 than in 2000. In 2012, the frequency distribution for values of pH, organic matter, available phosphate, and exchangeable potassium, calcium, and magnesium that were within the optimum range was 16.0%, 22.5%, 11.5%, 3.5%, 2.5%, and 5.0%, respectively. Especially, available phosphate and exchangeable calcium were excess level with portions of 76.0% and 96.5%, respectively. These results indicated that a balanced management of soil chemical properties can reduce the amount of fertilizer applied for sustainable agriculture in controlled horticultural lands.

Chemical Treatment of Low-level Radioactive Liquid Waste (I)

  • Lee, Sang-Hoon;Choe, Jong-In;Kim, Yong-Eak
    • Nuclear Engineering and Technology
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    • v.8 no.2
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    • pp.69-76
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    • 1976
  • This experiment has been carried out for the removal of long-lived radioactive-nuclides (Sr-90, Ru-106, Cs-137 and Ce-144) contained in the low-level radioactive effluents from the spent fuel reprocessing plant and nuclear power plant, in order to determine the decontaminability of various chemical coagulants and domestic clay mineral (montmorillonite). Phosphate process showed prominent efficiency for the removal of Ce-144, and lime-soda process did good removal efficiency for Sr-90. About Cs-137 copper-ferrocyanide process is much desirable. In phosphate or lime-soda process, most favorable removal efficiency was obtained at more than pH 11. The montmorillonite treated with sodium chloride showed a considerable improvement in the removal of the radioactive-nuclides. By a combined chemicals-montmorillionite process, the radioactive-nuclides could be more effectively removed than by the only chemicals process.

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