• Title/Summary/Keyword: Sodium effect

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Action of Aconite on Sodium-Potassium Activated ATPase in Rabbit Red Cell Membrane (토끼 적혈구막의 NaK ATPase의 활성도에 대한 aconite의 작용)

  • Koh, Il-Sup
    • The Korean Journal of Physiology
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    • v.10 no.1
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    • pp.15-24
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    • 1976
  • The action of aconite on the sodium plus potassium activated ATPase activity in the rabbit red cell membrane has been investigated and the experiments were also designed to determine the mechanism of action of aconite on the ATPase activity. The following results were observed. 1. The activity of the NaK ATPase from red cell membrane is stimulated by aconite, and the concentration of aconite for maximal activity is about 80 mg%. The pH optimum for the aconite sensitive component is 8.0. 2. The activating effect of aconite on the ATPase, with a given concentration of sodium in the medium, is increased by raising the potassium concentration but activity ratio is decreased. 3. The activating effect of aconite on the ATPase, with a given concentration of potassium in the medium, is increased by raising the sodium concentration but activity ratio is decreased. 4. The action of aconite on the ATPase activity is inhibited by calcium ions and the effect of inhibition is increased by small amounts of calcium but decreased by larger amounts. 5. The activating effect of aconite on the ATPase was not related to the sulfhydryl group of cysteine, the amino group of lysine, the hydroxyl group of threonine or the imidazole group of histidine. 6. The action of aconite on the ATPase activity is due to carboxyl group of the enzyme of NaK ATPase.

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Action of Ascorbic acid on Sodium-Potassium activated ATPase in Red Cell Membrane (적혈구막의 NaK ATPase의 활성도에 대한 ascorbic acid의 작용)

  • Koh, Il-Sup
    • The Korean Journal of Physiology
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    • v.12 no.1_2
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    • pp.15-23
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    • 1978
  • The action of ascorbic acid on the sodium Plus potassium activated ATPase activity in the rabbit red cell membrane has been investigated and the experiments were also designed to determine the mechanism of action if ascorbic acid on the ATPase activity The following results were observed. 1. The activity of the NaK ATPase from red cell membrane is stimulated by ascorbic acid and the concentration of ascorbic acid for maximal activity is about 8 mM. 2. The activating effect of ascorbic acid on the ATPase activaty, with a given concentration of sodium in the medium, is increased by raisins the potassium concentration but activity ratio is decreased. 3. The activating effect of ascorbic acid on the ATPase activity, with a given concentration of potassium in the medium, is increased by raising the sodium concentration but activity ratio is decreased. 4. The action of ascorbic acid on the ATPase activity is stimulated by calcium ions and activity ratio is increased by raising the calcium concentration. 5. The activating effect of ascorbic acid on the ATPase activity was not related to the sulfhydryl group of cysteine or the hydroxyl group of threonine. 6. The activating effect of ascorbic acid on the ATPase activity is due to amino group and carboxyl group of the enzyme of NaK ATPase.

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Action of Theobromine on Sodium-Potassium activated ATPase in Red Cell Membrane (Theobromine이 적혈구막의 NaK ATPase의 활성도에 대한 작용)

  • Koh, Il-Sup
    • The Korean Journal of Physiology
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    • v.12 no.1_2
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    • pp.25-34
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    • 1978
  • The action of theobromine on the sodium plus potassium activated ATPase activity In the rabbit red cell membrane has teen investigated and the experiments were also designed to determine the mechanism of action of theobromine on the ATPase activity. The following results were observed. 1. The activity of the NaK ATPase from red fell membrane is stimulated by theobromine, and the concentration of theobromine for maximal activity is about 3mM. 2. The activating effect of theobromine on the ATPase, with a given concentration of potassium in the medium, is increased by raising the sodium concentration but activity ratio is decreased. 3. The activating effect of theobromine on the ATPase, with a given concentration of sodium in the medium. is increased by the raising the potassium concentration but activity ratio is decreased. 4. The NaK ATPase activity is increased by small amounts of calcium but decreased by larger amounts. The activity of the enzyme by theobromine is increased by small amounts of calcium but decreased by larger amounts. 5. The activating effect of theobromine on the ATPase was not related to the hydroxyl group of threonine and imidazole group of histicline. 6. The activating effect of theobromine on the ATPase is due to sulfhydryl group, amino group and carboxyl group of the enzyme of NaK ATPase.

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Optimization of outer core to reduce end effect of annular linear induction electromagnetic pump in prototype Generation-IV sodium-cooled fast reactor

  • Kwak, Jaesik;Kim, Hee Reyoung
    • Nuclear Engineering and Technology
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    • v.52 no.7
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    • pp.1380-1385
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    • 2020
  • An annular linear induction electromagnetic pump (ALIP) which has a developed pressure of 0.76 bar and a flow rate of 100 L/min is designed to analysis end effect which is main problem to use ALIP in thermohydraulic system of the prototype generation-IV sodium-cooled fast reactor (PGSFR). Because there is no moving part which is directly in contact with the liquid, such as the impeller of a mechanical pump, an ALIP is one of the best options for transporting sodium, considering the high temperature and reactivity of liquid sodium. For the analysis of an ALIP, some of the most important characteristics are the electromagnetic properties such as the magnetic field, current density, and the Lorentz force. These electromagnetic properties not only affect the performance of an ALIP, but they additionally influence the end effect. The end effect is caused by distortion to the electromagnetic field at both ends of an ALIP, influencing both the flow stability and developed pressure. The electromagnetic field distribution in an ALIP is analyzed in this study by solving Maxwell's equations and using numerical analysis.

Action of Pilocarpine on Sodium-Potassium activated ATPase in Rabbit Red Cell Membrane (Pilocarpine이 토끼 적혈구막의 NaK ATPase의 활성도에 대한 작용)

  • Koh, Il-Sup
    • The Korean Journal of Physiology
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    • v.11 no.1
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    • pp.11-20
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    • 1977
  • The action of pilocarpine on the sodium plus potassium activated ATPase activity in the rabbit red cell membrane has been investigated and the experiments were also designed to determine the mechanism of action of pilocarpine on the ATPase activity. The following results were observed. 1. The activity of the NaK ATPase from red cell membrane is stimulated by pilocarpine, and the concentration of pilocarpine for maximal activity is about 3 mM. The pH optimum for the pilocarpine sensitive component is 8.0. 2. The activating effect of pilocarpine on the ATPase, with a given concentration of sodium .in the medium, is increased by raising the potassium concentration but activity ratio is decreased 3. The activating effect of pilocarpine on the ATPase, with a given concentration of Potassium in the medium, is increased by raising the sodium concentration but activity ratio is decreased 4. The NaK ATPase activity is increased by small amounts of calcium but decreased by 'larger amounts. The activity ratio of the enzyme by pilocarpine is decreased by small amounts .of calcium but decreased by larger amounts. 5. The activating effect of pilocarpine on the ATPase was not related to the sulfhydryl group of cysteine, the hydroxyl group of threonine or the imidazole group of histidine. 6. The activating effect of pilocarpine on the ATPase is due to amino group and carboxyl group of the enzyme of NaK ATPase

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Effect of Halothane vs. Pentobarbital Sodium Anaesthesia on Implantation and Foetal Development in Rabbits Ovariectomized on Day 2 after Insemination on Day 1 (토끼의 임신에 대한 Halothane 및 Pentobarbital Sodium 마취의 영향)

  • Kwun, Jong Kuk
    • Korean Journal of Veterinary Research
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    • v.15 no.1
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    • pp.1-3
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    • 1975
  • The effects of halothane and pentobarbital sodium anaesthesia in implantation and maintenance of pregnancy were compared in the rabbit ovariectomized the day after insemination and given steroid replacement therapy. The result has shown that halothane anaesthesia did not favour the overall process of implantation or foetal development, compared with pentobarbital sodium.

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The effect of sodium aluminate concentration of oxide layer coated at AZ31 magnesium alloy by plasma electrolytic oxidation (AZ31 마그네슘 합금의 PEO 처리시 Sodium Aluminate 전해질이 산화막 특성에 미치는 영향)

  • Lee, Jong-Seok;Baek, Hong-Gu;Kim, Seong-Wan
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2012.05a
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    • pp.311-312
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    • 2012
  • PEO(Plasma Electrolytic Oxidation) 방법으로 인한 마그네슘 합금의 산화막 코팅시 Sodium Aluminate의 역할을 알아보았다. 전해액 내에 Sodium Aluminate 의 농도가 증가할수록 Plasma arc 발생에 필요한 전압의 상승이 빨라졌으며 그 산화막이 치밀해짐을 알 수 있었다. 또한 치밀한 산화막의 기공률은 분석하여 이를 내식성 결과와 비교함으로써 산화막의 기공률이 내식성에 미치는 영향을 고찰해보았다.

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Customers' Perceptions of Operational Status of and Needs for Sodium Reduction in the Industry Foodservice in Seoul (서울지역 산업체 급식소 고객의 급식 나트륨 저감화 운영 및 필요성에 대한 인식)

  • Yi, Na-Young
    • Korean Journal of Community Nutrition
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    • v.25 no.1
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    • pp.21-31
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    • 2020
  • Objectives: This study aimed to compare customers' perceptions of the need for a low-sodium diet and sodium-reduced operations in the industry foodservice by age. The relationships between health concerns and perceptions of the need for sodium-reduced operations and low-sodium diets in the industry foodservice were analyzed. Methods: A survey was conducted among 340 industry foodservice customers aged 20-50 years and residing in Seoul, Korea. This study investigated the respondents' health concerns, their perception of the need for sodium-reduced foodservice operations, their perception of a sodium-reduced diet, and the general details of the foodservices they used. A cross-tabulation analysis and ANOVA were performed to identify differences in measurement items by age, and a simple regression analysis was performed to examine relationships between measurement items. Results: For the customers' perception of the need for a sodium-reduced foodservice operation, the item "it is necessary to provide separate spices and sauces to reduce sodium intake" achieved the highest score (3.88 points out of a possible 5 points). For the perception of a sodium-reduced diet, the item "I think it is helpful for one's health" obtained the highest score (4.13 points). Respondents' health concerns had a positive effect on increasing the level of perception of the need for sodium-reduced foodservice operations and that of a sodium-reduced diet. Conclusions: Foodservice nutritionists could help enhance their customers' perceptions of the needs for sodium-reduced foodservice operations and sodium-reduced diets by frequently providing them with sodium-related health information.

The Effect of Sodium Lactate and Sodium Chloride on Water Activity of Water-Sorbitol System (Water-Sorbitol System의 수분활성도에 미치는 Sodium Lactate 및 Sodium Chloride의 영향)

  • Park, Jang-Woo;Rhee, Chul
    • Korean Journal of Food Science and Technology
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    • v.23 no.3
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    • pp.330-335
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    • 1991
  • The values of water activity in the different concentrations of NaCl and sodium lactate were measured by hygrometer in the water-sorbitol systems. Interaction of NaCl and sodium lactate was evaluated by Raoult's law. The discrepancy between experimental and theoretical value by the Raoult's law was defined as interaction between water-sorbitol and added solutes in the systems. The changes of interacted water and solutes were observed in whole range of water activity. The value of interacted water (water: sorbitol=1 : 1.1241) obtained by added sodium lactate was found to be higher than sodium chloride. The amount of interacted solute reached maximum about Aw 0.87, while the interactions between added solute and sorbitol showed an increasing tendency below Aw 0.87.

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The Improving Effect of Paeoniae Radix on Dextran Sulfate Sodium-induced Colitis in Mice (Dextran Sulfate Sodium으로 유도된 궤양성 대장염에 대한 작약의 개선 효과)

  • Myung, Noh Yil
    • Korean Journal of Plant Resources
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    • v.31 no.4
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    • pp.275-282
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    • 2018
  • Paeoniae Radix has been used as a traditional medicine for various diseases including hepatic disease. However, the inhibitory effect of Paeoniae Radix on intestinal inflammation has not been fully understood yet. The aim of this study was to evaluate the effect of Paeoniae Radix on colitis induced by dextran sulfate sodium in mice. To investigate the protective effects of Paeoniae Radix, the colitis mice were induced by drinking water containing 5% dextran sulfate sodium for 7 days. Mice were randomized into groups receiving Paeoniae Radix (100 mg/kg), sulfasalazine (150 mg/kg) as a positive control, or water as a negative control. We evaluated the effects of Paeoniae Radix on clinical signs induced by dextran sulfate sodium, measuring weight loss, colon length, and disease activity index. Additionally, to find a possible explanation for the anti-inflammatory effects of Paeoniae Radix, we evaluated the effects of Paeoniae Radix on the interleukin-6 and cyclooxygenase-2 levels in colitis tissue. The results indicated that mice treated with dextran sulfate sodium showed measurable clinical signs, including weight loss and reduced colon length. However, Paeoniae Radix treatment significantly improved the weight loss and disease activity index as clinical symptoms. Moreover, Paeoniae Radix inhibited the interleukin-6 and cyclooxygenase-2 expression levels in colon tissues treated with dextran sulfate sodium. Taken together, the findings of this study suggest that Paeoniae Radix may be useful for treating intestinal inflammation, including ulcerative colitis.